Published in J Genet Couns on May 01, 2014
Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote. PLoS Biol (2006) 5.44
Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres. Cell (2006) 4.13
Risk stratification for primary implantation of a cardioverter-defibrillator in patients with ischemic left ventricular dysfunction. J Am Coll Cardiol (2008) 3.73
Targeted enrichment beyond the consensus coding DNA sequence exome reveals exons with higher variant densities. Genome Biol (2011) 3.09
Free radicals, antioxidants in disease and health. Int J Biomed Sci (2008) 2.89
Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis. EMBO J (2007) 2.61
Genetic predictors and remodeling of dilated cardiomyopathy in muscular dystrophy. Circulation (2005) 2.58
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Starvation-induced cleavage of the tRNA anticodon loop in Tetrahymena thermophila. J Biol Chem (2005) 2.26
Telomerase RNA level limits telomere maintenance in X-linked dyskeratosis congenita. Genes Dev (2006) 2.20
Subnuclear shuttling of human telomerase induced by transformation and DNA damage. Nat Cell Biol (2002) 2.10
Two classes of endogenous small RNAs in Tetrahymena thermophila. Genes Dev (2005) 2.08
Distinct biogenesis pathways for human telomerase RNA and H/ACA small nucleolar RNAs. Mol Cell (2003) 2.07
Stepwise protein-mediated RNA folding directs assembly of telomerase ribonucleoprotein. Nature (2007) 2.05
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses. Proc Natl Acad Sci U S A (2005) 2.01
Ocular demodicosis as a risk factor of pterygium recurrence. Ophthalmology (2013) 2.00
Template boundary definition in Tetrahymena telomerase. Genes Dev (2002) 1.96
Clinical spectrum, morbidity, and mortality in 113 pediatric patients with mitochondrial disease. Pediatrics (2004) 1.95
Disorders of left-right asymmetry: heterotaxy and situs inversus. Am J Med Genet C Semin Med Genet (2009) 1.89
Human telomerase domain interactions capture DNA for TEN domain-dependent processive elongation. Mol Cell (2011) 1.87
Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation. Mol Cell (2007) 1.87
Roles for RNA in telomerase nucleotide and repeat addition processivity. Mol Cell (2003) 1.86
Holoenzyme proteins required for the physiological assembly and activity of telomerase. Genes Dev (2004) 1.86
The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres. EMBO J (2010) 1.83
Physical and functional coupling of RNA-dependent RNA polymerase and Dicer in the biogenesis of endogenous siRNAs. Nat Struct Mol Biol (2007) 1.80
RNA-based affinity purification reveals 7SK RNPs with distinct composition and regulation. RNA (2007) 1.77
Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis. J Allergy Clin Immunol (2010) 1.74
Rare copy number variations in congenital heart disease patients identify unique genes in left-right patterning. Proc Natl Acad Sci U S A (2011) 1.71
Genetic testing practices in infants with congenital heart disease. Congenit Heart Dis (2013) 1.65
A Tetrahymena Piwi bound to mature tRNA 3' fragments activates the exonuclease Xrn2 for RNA processing in the nucleus. Mol Cell (2012) 1.65
Congenital heart surgery in infants: effects of acute kidney injury on outcomes. J Thorac Cardiovasc Surg (2011) 1.62
Telomerase recognizes its template by using an adjacent RNA motif. Proc Natl Acad Sci U S A (2002) 1.61
Genetics of human heterotaxias. Eur J Hum Genet (2006) 1.59
Two purified domains of telomerase reverse transcriptase reconstitute sequence-specific interactions with RNA. J Biol Chem (2005) 1.58
Coffin-Lowry syndrome and left ventricular noncompaction cardiomyopathy with a restrictive pattern. Am J Med Genet A (2011) 1.54
How does amniotic membrane work? Ocul Surf (2004) 1.51
Depression among older adults in the United States and England. Am J Geriatr Psychiatry (2010) 1.48
Biogenesis of telomerase ribonucleoproteins. RNA (2012) 1.47
Specificity requirements for human telomere protein interaction with telomerase holoenzyme. J Biol Chem (2012) 1.47
Initiation of Primary Care-Mental Health Integration programs in the VA Health System: associations with psychiatric diagnoses in primary care. Med Care (2010) 1.46
The evolving role of the total artificial heart in the management of end-stage congenital heart disease and adolescents. ASAIO J (2014) 1.45
Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers have no beneficial effect on ablation outcome in chronic persistent atrial fibrillation. Acta Cardiol (2009) 1.42
Refined annotation and assembly of the Tetrahymena thermophila genome sequence through EST analysis, comparative genomic hybridization, and targeted gap closure. BMC Genomics (2008) 1.40
The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo. Development (2006) 1.40
An RPA-related sequence-specific DNA-binding subunit of telomerase holoenzyme is required for elongation processivity and telomere maintenance. Mol Cell (2009) 1.39
Electrocardiographic abnormalities and arrhythmias are strongly associated with the development of cardiomyopathy in muscular dystrophy. Heart Rhythm (2010) 1.37
High prevalence of eosinophilic esophagitis in patients with inherited connective tissue disorders. J Allergy Clin Immunol (2013) 1.35
A telomerase holoenzyme protein enhances telomerase RNA assembly with telomerase reverse transcriptase. Nat Struct Mol Biol (2005) 1.35
A complex syndrome of left-right axis, central nervous system and axial skeleton defects in Zic3 mutant mice. Development (2002) 1.35
Validation of serum markers for blood-brain barrier disruption in traumatic brain injury. J Neurotrauma (2009) 1.34
Sequence, biogenesis, and function of diverse small RNA classes bound to the Piwi family proteins of Tetrahymena thermophila. Genes Dev (2009) 1.34
The architecture of Tetrahymena telomerase holoenzyme. Nature (2013) 1.32
Chiral drugs: an overview. Int J Biomed Sci (2006) 1.31
A growth-essential Tetrahymena Piwi protein carries tRNA fragment cargo. Genes Dev (2010) 1.30
Effectiveness of mechanical circulatory support in children with acute fulminant and persistent myocarditis. J Card Fail (2011) 1.29
Human Y5 RNA specializes a Ro ribonucleoprotein for 5S ribosomal RNA quality control. Genes Dev (2007) 1.27
On the impact of parametric assumptions and robust alternatives for longitudinal data analysis. Biom J (2009) 1.24
A novel method of isolation, preservation, and expansion of human corneal endothelial cells. Invest Ophthalmol Vis Sci (2007) 1.24
Telomerase RNA deficiency in peripheral blood mononuclear cells in X-linked dyskeratosis congenita. Hum Genet (2004) 1.22
Specificity and stoichiometry of subunit interactions in the human telomerase holoenzyme assembled in vivo. Mol Cell Biol (2010) 1.22
Biological and biochemical functions of RNA in the tetrahymena telomerase holoenzyme. Mol Cell Biol (2005) 1.22
High-resolution physical and functional mapping of the template adjacent DNA binding site in catalytically active telomerase. Proc Natl Acad Sci U S A (2007) 1.21
Human telomerase and Cajal body ribonucleoproteins share a unique specificity of Sm protein association. Genes Dev (2006) 1.21
Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. Gastroenterology (2006) 1.20
Use of ventricular assist devices in children across the United States: analysis of 7.5 million pediatric hospitalizations. Ann Thorac Surg (2010) 1.19
Multiple mechanisms for elongation processivity within the reconstituted tetrahymena telomerase holoenzyme. J Biol Chem (2010) 1.19
Identification of nitrogen starvation-responsive microRNAs in Arabidopsis thaliana. PLoS One (2012) 1.18
Sex differences in outcome after mild traumatic brain injury. J Neurotrauma (2010) 1.18
Prevalence and distribution of late gadolinium enhancement in a large population of patients with Duchenne muscular dystrophy: effect of age and left ventricular systolic function. J Cardiovasc Magn Reson (2013) 1.18
Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function. RNA (2006) 1.17
Investigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants. J Biol Chem (2009) 1.17
Genome-Scale Analysis of Programmed DNA Elimination Sites in Tetrahymena thermophila. G3 (Bethesda) (2011) 1.16
Kawasaki disease in the adult: a case report and review of the literature. Tex Heart Inst J (2004) 1.16
A novel RNA binding domain in tetrahymena telomerase p65 initiates hierarchical assembly of telomerase holoenzyme. Mol Cell Biol (2006) 1.16
Calcium-induced abnormal epidermal-like differentiation in cultures of mouse corneal-limbal epithelial cells. Invest Ophthalmol Vis Sci (2004) 1.14
Identification and functional characterization of NODAL rare variants in heterotaxy and isolated cardiovascular malformations. Hum Mol Genet (2008) 1.14
Human telomerase reverse transcriptase motifs required for elongation of a telomeric substrate. J Biol Chem (2003) 1.14
Human amniotic epithelial cells as novel feeder layers for promoting ex vivo expansion of limbal epithelial progenitor cells. Stem Cells (2007) 1.13
Amniotic membrane induces apoptosis of interferon-gamma activated macrophages in vitro. Exp Eye Res (2005) 1.13
Prevalence, morbidity, and mortality of heart failure-related hospitalizations in children in the United States: a population-based study. J Card Fail (2012) 1.13
Characterization and comparison of intercellular adherent junctions expressed by human corneal endothelial cells in vivo and in vitro. Invest Ophthalmol Vis Sci (2008) 1.12
Functional variant in the autophagy-related 5 gene promotor is associated with childhood asthma. PLoS One (2012) 1.12
An enhanced H/ACA RNP assembly mechanism for human telomerase RNA. Mol Cell Biol (2012) 1.11
Human keratocytes cultured on amniotic membrane stroma preserve morphology and express keratocan. Invest Ophthalmol Vis Sci (2003) 1.11
Ventricular remodeling and survival are more favorable for myocarditis than for idiopathic dilated cardiomyopathy in childhood: an outcomes study from the Pediatric Cardiomyopathy Registry. Circ Heart Fail (2010) 1.10
Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences. PLoS One (2011) 1.10
Human telomerase specialization for repeat synthesis by unique handling of primer-template duplex. EMBO J (2014) 1.09
Ginsenoside-Rd from panax notoginseng blocks Ca2+ influx through receptor- and store-operated Ca2+ channels in vascular smooth muscle cells. Eur J Pharmacol (2006) 1.09
Differences in candidate gene association between European ancestry and African American asthmatic children. PLoS One (2011) 1.09
Intrastromal invasion by limbal epithelial cells is mediated by epithelial-mesenchymal transition activated by air exposure. Am J Pathol (2005) 1.08
Characterization of corneal pannus removed from patients with total limbal stem cell deficiency. Invest Ophthalmol Vis Sci (2004) 1.07
Synthesis, crystallographic and theoretical studies of the new Zintl phases Ba2Cd2Pn3 (Pn = As, Sb), and the solid solutions (Ba(1-x)Sr(x))2Cd2Sb3 and Ba2Cd2(Sb(1-x)As(x))3. Dalton Trans (2009) 1.07
Development and validation of a 6-day standard for the identification of frequent mental distress. Soc Psychiatry Psychiatr Epidemiol (2010) 1.07
Structural basis for telomerase RNA recognition and RNP assembly by the holoenzyme La family protein p65. Mol Cell (2012) 1.06
The fate of limbal epithelial progenitor cells during explant culture on intact amniotic membrane. Invest Ophthalmol Vis Sci (2007) 1.05
Preservation and expansion of the primate keratocyte phenotype by downregulating TGF-beta signaling in a low-calcium, serum-free medium. Invest Ophthalmol Vis Sci (2006) 1.04
The 5' guanosine tracts of human telomerase RNA are recognized by the G-quadruplex binding domain of the RNA helicase DHX36 and function to increase RNA accumulation. Mol Cell Biol (2010) 1.04