Published in Infect Immun on May 19, 2014
Plasmid-encoded Pgp3 is a major virulence factor for Chlamydia muridarum to induce hydrosalpinx in mice. Infect Immun (2014) 1.00
In vitro passage selects for Chlamydia muridarum with enhanced infectivity in cultured cells but attenuated pathogenicity in mouse upper genital tract. Infect Immun (2015) 0.93
Intrauterine infection with plasmid-free Chlamydia muridarum reveals a critical role of the plasmid in chlamydial ascension and establishes a model for evaluating plasmid-independent pathogenicity. Infect Immun (2015) 0.84
Antigen specific immune response in Chlamydia muridarum genital infection is dependent on murine microRNAs-155 and -182. Oncotarget (2016) 0.79
A re-evaluation of the role of B cells in protective immunity to Chlamydia infection. Immunol Lett (2015) 0.78
The Chlamydia-Secreted Protease CPAF Promotes Chlamydial Survival in the Mouse Lower Genital Tract. Infect Immun (2016) 0.78
Plasmid-Encoded Pgp5 Is a Significant Contributor to Chlamydia muridarum Induction of Hydrosalpinx. PLoS One (2015) 0.78
Chlamydial Plasmid-Dependent Pathogenicity. Trends Microbiol (2016) 0.77
Intravenous Inoculation with Chlamydia muridarum Leads to a Long-Lasting Infection Restricted to the Gastrointestinal Tract. Infect Immun (2016) 0.75
Chlamydia muridarum induction of glandular duct dilation in mice. Infect Immun (2015) 0.75
Uterotubal junction prevents chlamydial ascension via innate immunity. PLoS One (2017) 0.75
Chlamydia muridarum with mutations in chromosomal genes tc0237 and/or tc0668 are deficient in colonizing mouse gastrointestinal tract. Infect Immun (2017) 0.75
Generation of C5a in the absence of C3: a new complement activation pathway. Nat Med (2006) 5.26
Immunity to murine chlamydial genital infection. Infect Immun (2002) 4.64
Identification of a chlamydial protease-like activity factor responsible for the degradation of host transcription factors. J Exp Med (2001) 4.27
Prevention of Chlamydia-induced infertility by inhibition of local caspase activity. J Infect Dis (2013) 2.79
Protective efficacy of major outer membrane protein-specific immunoglobulin A (IgA) and IgG monoclonal antibodies in a murine model of Chlamydia trachomatis genital tract infection. Infect Immun (1995) 2.55
Toll-like receptor-2, but not Toll-like receptor-4, is essential for development of oviduct pathology in chlamydial genital tract infection. J Immunol (2003) 2.44
A predominant role for antibody in acquired immunity to chlamydial genital tract reinfection. J Immunol (2005) 2.26
Function, structure and therapeutic potential of complement C5a receptors. Br J Pharmacol (2007) 2.25
Vaccination with the Chlamydia trachomatis major outer membrane protein can elicit an immune response as protective as that resulting from inoculation with live bacteria. Infect Immun (2005) 2.13
Production, specificity, and functionality of monoclonal antibodies to specific peptide-major histocompatibility complex class II complexes formed by processing of exogenous protein. Proc Natl Acad Sci U S A (1997) 2.13
Molecular intercommunication between the complement and coagulation systems. J Immunol (2010) 2.12
Histopathologic changes related to fibrotic oviduct occlusion after genital tract infection of mice with Chlamydia muridarum. Sex Transm Dis (2005) 1.96
The complement system. Cell Tissue Res (2010) 1.86
Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection. Infect Immun (2007) 1.85
Sexually transmitted diseases and tubal pregnancy. Sex Transm Dis (1991) 1.69
Human antibody responses to a Chlamydia-secreted protease factor. Infect Immun (2004) 1.59
Mice deficient in MyD88 Develop a Th2-dominant response and severe pathology in the upper genital tract following Chlamydia muridarum infection. J Immunol (2010) 1.49
Tumor necrosis factor alpha production from CD8+ T cells mediates oviduct pathological sequelae following primary genital Chlamydia muridarum infection. Infect Immun (2011) 1.48
Antibody in host defense against mouse pneumonitis agent (murine Chlamydia trachomatis). Infect Immun (1984) 1.47
The hypothetical protein CT813 is localized in the Chlamydia trachomatis inclusion membrane and is immunogenic in women urogenitally infected with C. trachomatis. Infect Immun (2006) 1.47
C5a receptor (CD88) blockade protects against MPO-ANCA GN. J Am Soc Nephrol (2013) 1.38
Interleukin-12 production is required for chlamydial antigen-pulsed dendritic cells to induce protection against live Chlamydia trachomatis infection. Infect Immun (1999) 1.35
Chlamydia trachomatis pulmonary infection induces greater inflammatory pathology in immunoglobulin A deficient mice. Cell Immunol (2004) 1.34
Immunogenicity evaluation of a lipidic amino acid-based synthetic peptide vaccine for Chlamydia trachomatis. J Immunol (1993) 1.32
C5a mutants are potent antagonists of the C5a receptor (CD88) and of C5L2: position 69 is the locus that determines agonism or antagonism. J Biol Chem (2003) 1.22
International Union of Basic and Clinical Pharmacology. [corrected]. LXXXVII. Complement peptide C5a, C4a, and C3a receptors. Pharmacol Rev (2013) 1.22
Complement activation and stimulation of chemotaxis by Chlamydia trachomatis. Infect Immun (1985) 1.20
Immunoaccessible peptide sequences of the major outer membrane protein from Chlamydia trachomatis serovar C. Infect Immun (1990) 1.19
Inhibition of matrix metalloproteinases protects mice from ascending infection and chronic disease manifestations resulting from urogenital Chlamydia muridarum infection. Infect Immun (2006) 1.17
C5a promotes development of experimental lupus nephritis which can be blocked with a specific receptor antagonist. Eur J Immunol (2005) 1.16
Role for inducible nitric oxide synthase in protection from chronic Chlamydia trachomatis urogenital disease in mice and its regulation by oxygen free radicals. Infect Immun (2001) 1.15
Reduced live organism recovery and lack of hydrosalpinx in mice infected with plasmid-free Chlamydia muridarum. Infect Immun (2013) 1.10
Oviduct infection and hydrosalpinx in DBA1/j mice is induced by intracervical but not intravaginal inoculation with Chlamydia muridarum. PLoS One (2013) 1.06
Chlamydial induction of hydrosalpinx in 11 strains of mice reveals multiple host mechanisms for preventing upper genital tract pathology. PLoS One (2014) 1.04
Lack of long-lasting hydrosalpinx in A/J mice correlates with rapid but transient chlamydial ascension and neutrophil recruitment in the oviduct following intravaginal inoculation with Chlamydia muridarum. Infect Immun (2014) 1.01
Significant role of IL-1 signaling, but limited role of inflammasome activation, in oviduct pathology during Chlamydia muridarum genital infection. J Immunol (2012) 0.97
Signaling via tumor necrosis factor receptor 1 but not Toll-like receptor 2 contributes significantly to hydrosalpinx development following Chlamydia muridarum infection. Infect Immun (2014) 0.94
Functional roles for C5a and C5aR but not C5L2 in the pathogenesis of human and experimental cerebral malaria. Infect Immun (2013) 0.93
Innate immunity is sufficient for the clearance of Chlamydia trachomatis from the female mouse genital tract. Pathog Dis (2014) 0.93
Complement activation in malaria: friend or foe? Trends Mol Med (2014) 0.92
A new role of the complement system: C3 provides protection in a mouse model of lung infection with intracellular Chlamydia psittaci. PLoS One (2012) 0.92
Induction of protective immunity against Chlamydia muridarum intravaginal infection with a chlamydial glycogen phosphorylase. PLoS One (2012) 0.91
A role for CXC chemokine receptor-2 in the pathogenesis of urogenital Chlamydia muridarum infection in mice. FEMS Immunol Med Microbiol (2010) 0.90
Novel roles for complement receptors in T cell regulation and beyond. Mol Immunol (2013) 0.89
Distinct roles of CD28- and CD40 ligand-mediated costimulation in the development of protective immunity and pathology during Chlamydia muridarum urogenital infection in mice. Infect Immun (2009) 0.89
Early complement components enhance neutralization of Chlamydia trachomatis infectivity by human sera. Infect Immun (1992) 0.88
Characterization of kinetics and target proteins for binding of human complement component C3 to the surface-exposed outer membrane of Chlamydia trachomatis serovar L2. Infect Immun (1993) 0.88
Influence of TRAF1/C5 and STAT4 genes polymorphisms on susceptibility and severity of rheumatoid arthritis in Egyptian population. Cell Immunol (2011) 0.87
Structure, function and control of complement C5 and its proteolytic fragments. Curr Mol Med (2012) 0.86
Complement 5a stimulates hepatic stellate cells in vitro, and is increased in the plasma of patients with chronic hepatitis B. Immunology (2013) 0.85
The complement anaphylatoxin C3a receptor (C3aR) contributes to the inflammatory response in dextran sulfate sodium (DSS)-induced colitis in mice. PLoS One (2013) 0.84
Sublytic C5b-9 induces IL-6 and TGF-β1 production by glomerular mesangial cells in rat Thy-1 nephritis through p300-mediated C/EBPβ acetylation. FASEB J (2013) 0.84
Complement-mediated cellular injury. Semin Nephrol (2013) 0.83
The complement C3a receptor is critical in defense against Chlamydia psittaci in mouse lung infection and required for antibody and optimal T cell response. J Infect Dis (2013) 0.79
Inactivation of C5a anaphylatoxin by a peptide that is complementary to a region of C5a. J Immunol (2004) 0.79
C5aR and C5L2 act in concert to balance immunometabolism in adipose tissue. Mol Cell Endocrinol (2013) 0.77
A complement a day keeps the Fox(p3) away. Nat Immunol (2013) 0.77
Lack of long-lasting hydrosalpinx in A/J mice correlates with rapid but transient chlamydial ascension and neutrophil recruitment in the oviduct following intravaginal inoculation with Chlamydia muridarum. Infect Immun (2014) 1.01
In vitro passage selects for Chlamydia muridarum with enhanced infectivity in cultured cells but attenuated pathogenicity in mouse upper genital tract. Infect Immun (2015) 0.93
In Vivo and Ex Vivo Imaging Reveals a Long-Lasting Chlamydial Infection in the Mouse Gastrointestinal Tract following Genital Tract Inoculation. Infect Immun (2015) 0.85
The Chromosome-Encoded Hypothetical Protein TC0668 Is an Upper Genital Tract Pathogenicity Factor of Chlamydia muridarum. Infect Immun (2015) 0.82
Characterization of CPAF critical residues and secretion during Chlamydia trachomatis infection. Infect Immun (2015) 0.79
Chlamydia muridarum induction of glandular duct dilation in mice. Infect Immun (2015) 0.75