Published in Proc Natl Acad Sci U S A on June 02, 2014
Targeting non-coding RNAs with the CRISPR/Cas9 system in human cell lines. Nucleic Acids Res (2014) 1.26
Radiation-sensitive severe combined immunodeficiency: The arguments for and against conditioning before hematopoietic cell transplantation-what to do? J Allergy Clin Immunol (2015) 0.83
Stem cells: the pursuit of genomic stability. Int J Mol Sci (2014) 0.77
Ligase-4 Deficiency Causes Distinctive Immune Abnormalities in Asymptomatic Individuals. J Clin Immunol (2016) 0.76
Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks. Oncotarget (2017) 0.75
Loss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome. PLoS One (2016) 0.75
Gene Editing Approaches against Viral Infections and Strategy to Prevent Occurrence of Viral Escape. PLoS Pathog (2016) 0.75
LIG4 mediates Wnt signalling-induced radioresistance. Nat Commun (2016) 0.75
CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism. Nat Commun (2016) 0.75
Rad51 Regulates Reprogramming Efficiency through DNA Repair Pathway. Balsaenggwa Saengsig (2016) 0.75
Induced Pluripotent Stem Cells: Advances in the Quest for Genetic Stability during Reprogramming Process. Int J Mol Sci (2017) 0.75
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu Rev Biochem (2010) 9.80
Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature (2009) 8.70
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature (2009) 7.96
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell (2002) 6.34
IgH class switching and translocations use a robust non-classical end-joining pathway. Nature (2007) 6.05
Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature (2009) 5.37
Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly. Cell (2006) 5.33
DNA repair is limiting for haematopoietic stem cells during ageing. Nature (2007) 4.71
Senescence impairs successful reprogramming to pluripotent stem cells. Genes Dev (2009) 4.69
Living on a break: cellular senescence as a DNA-damage response. Nat Rev Cancer (2008) 4.63
A molecular roadmap of reprogramming somatic cells into iPS cells. Cell (2012) 4.41
Regulation of homologous recombination in eukaryotes. Annu Rev Genet (2010) 4.33
Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations. Cell (2002) 4.29
DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway. Mol Cell (2000) 3.82
ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2. EMBO J (2009) 2.94
DNA ligase IV mutations identified in patients exhibiting developmental delay and immunodeficiency. Mol Cell (2001) 2.69
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Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: the molecular choreography. Mutat Res (2012) 2.28
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A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining. J Clin Invest (2008) 1.82
DNA damage responses in human induced pluripotent stem cells and embryonic stem cells. PLoS One (2010) 1.75
Lentiviral vector design and imaging approaches to visualize the early stages of cellular reprogramming. Mol Ther (2011) 1.69
Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cells. Stem Cells (2009) 1.68
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The impact of heterochromatin on DSB repair. Biochem Soc Trans (2009) 1.65
DNA-PKcs is critical for telomere capping. Proc Natl Acad Sci U S A (2001) 1.64
Retroviral DNA integration and the DNA damage response. Cell Death Differ (2005) 1.63
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Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells. Proc Natl Acad Sci U S A (2004) 1.53
Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state. Cell Rep (2013) 1.07
PRKDC mutations in a SCID patient with profound neurological abnormalities. J Clin Invest (2013) 1.06
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Human induced pluripotent cells resemble embryonic stem cells demonstrating enhanced levels of DNA repair and efficacy of nonhomologous end-joining. Mutat Res (2011) 1.01
Ataxia-telangiectasia mutated (ATM) deficiency decreases reprogramming efficiency and leads to genomic instability in iPS cells. Biochem Biophys Res Commun (2011) 1.01
Human embryonic stem cells are capable of executing G1/S checkpoint activation. Stem Cells (2010) 1.01
A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors. Cell Death Differ (2013) 0.99
Radiation-induced delayed cell death in a hypomorphic Artemis cell line. Hum Mol Genet (2006) 0.90
Brief report: a human induced pluripotent stem cell model of cernunnos deficiency reveals an important role for XLF in the survival of the primitive hematopoietic progenitors. Stem Cells (2013) 0.85
Reprogramming and the pluripotent stem cell cycle. Curr Top Dev Biol (2013) 0.81
N-acetylcysteine protects induced pluripotent stem cells from in vitro stress: impact on differentiation outcome. Int J Dev Biol (2012) 0.79