Published in Cell Rep on June 19, 2014
ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol (2015) 0.96
β2-spectrin depletion impairs DNA damage repair. Oncotarget (2016) 0.87
ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to Adaptor. Biomolecules (2015) 0.86
BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation. EMBO J (2015) 0.85
Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes. Nat Commun (2016) 0.83
The Functional Analysis of Histone Acetyltransferase MOF in Tumorigenesis. Int J Mol Sci (2016) 0.83
MOF maintains transcriptional programs regulating cellular stress response. Oncogene (2015) 0.82
A Perspective on Chromosomal Double Strand Break Markers in Mammalian Cells. Jacobs J Radiat Oncol (2015) 0.82
Single-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangs. Cancer Res (2015) 0.79
The many faces of histone H3K79 methylation. Mutat Res Rev Mutat Res (2016) 0.79
Acetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and Cancer. PLoS Genet (2016) 0.79
Arsenic Trioxide Reduces Global Histone H4 Acetylation at Lysine 16 through Direct Binding to Histone Acetyltransferase hMOF in Human Cells. PLoS One (2015) 0.78
Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitment. Nucleic Acids Res (2016) 0.78
Role of the Exocyst Complex Component Sec6/8 in Genomic Stability. Mol Cell Biol (2015) 0.77
Scaffold attachment factor A (SAF-A) and Ku temporally regulate repair of radiation-induced clustered genome lesions. Oncotarget (2016) 0.76
HOXC10 Expression Supports the Development of Chemotherapy Resistance by Fine Tuning DNA Repair in Breast Cancer Cells. Cancer Res (2016) 0.76
Targeted inhibition of histone deacetylases and hedgehog signaling suppress tumor growth and homologous recombination in aerodigestive cancers. Am J Cancer Res (2015) 0.76
MCL-1 depletion impairs DNA DSB repair and re-initiation of stalled DNA replication forks. Mol Cell Biol (2016) 0.76
TET1 modulates H4K16 acetylation by controlling auto-acetylation of hMOF to affect gene regulation and DNA repair function. Nucleic Acids Res (2016) 0.75
Detecting ATM-dependent chromatin modification in DNA damage response. Methods Mol Biol (2015) 0.75
Structure and function of histone acetyltransferase MOF. AIMS Biophys (2015) 0.75
A multifaceted role for MOF histone modifying factor in genome maintenance. Mech Ageing Dev (2016) 0.75
Torin2 Suppresses Ionizing Radiation-Induced DNA Damage Repair. Radiat Res (2016) 0.75
Histone acetyltransferase activity of MOF is required for adult, but not early fetal hematopoiesis in mice. Blood (2016) 0.75
Pluripotent Stem Cells and DNA Damage Response to Ionizing Radiations. Radiat Res (2016) 0.75
Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1. Oncotarget (2016) 0.75
USP7 saves RIDDLE for the end. Cell Cycle (2015) 0.75
Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells. Oncotarget (2016) 0.75
miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin. Sci Rep (2017) 0.75
Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis. Cancer Res (2017) 0.75
Histone acetyltransferase KAT8 is essential for mouse oocyte development by regulating reactive oxygen species levels. Development (2017) 0.75
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science (2007) 20.11
Human CtIP promotes DNA end resection. Nature (2007) 10.63
XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev (1999) 9.50
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell (2010) 8.70
Double-strand break end resection and repair pathway choice. Annu Rev Genet (2011) 7.31
Molecular views of recombination proteins and their control. Nat Rev Mol Cell Biol (2003) 6.96
Protein detection using proximity-dependent DNA ligation assays. Nat Biotechnol (2002) 6.05
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nat Struct Mol Biol (2010) 5.59
Playing the end game: DNA double-strand break repair pathway choice. Mol Cell (2012) 5.42
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more. Nat Rev Mol Cell Biol (2013) 5.33
Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex. Science (2004) 4.58
p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice. Mol Cell Biol (2003) 4.36
53BP1 regulates DSB repair using Rif1 to control 5' end resection. Science (2013) 4.00
Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination. Nat Struct Mol Biol (2013) 3.18
Exploiting heterogeneous sequence properties improves prediction of protein disorder. Proteins (2005) 3.14
RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection. Mol Cell (2013) 3.05
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching. Science (2013) 3.02
53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination. J Exp Med (2010) 2.81
hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells. Mol Cell Biol (2005) 2.69
Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1. Mol Cell (2011) 2.46
Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair. Cell Cycle (2009) 2.31
Involvement of human MOF in ATM function. Mol Cell Biol (2005) 2.30
Interplay between human DNA repair proteins at a unique double-strand break in vivo. EMBO J (2006) 2.09
The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis. Mol Cell Biol (2007) 2.07
53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions. Cell (2013) 2.05
MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair. Mol Cell Biol (2010) 2.03
Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability. J Biol Chem (2003) 2.03
RIF1 counteracts BRCA1-mediated end resection during DNA repair. J Biol Chem (2013) 1.86
Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair. Mol Cell Biol (2006) 1.84
hTERT associates with human telomeres and enhances genomic stability and DNA repair. Oncogene (2003) 1.78
Unrepaired clustered DNA lesions induce chromosome breakage in human cells. Proc Natl Acad Sci U S A (2011) 1.64
Ionizing radiation activates the ATM kinase throughout the cell cycle. Oncogene (2000) 1.60
MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1. Mol Cell Biol (2010) 1.57
Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status. Cancer Res (2007) 1.47
Genetic dissection of vertebrate 53BP1: a major role in non-homologous end joining of DNA double strand breaks. DNA Repair (Amst) (2006) 1.46
Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation. Mol Cell Biol (2003) 1.44
The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy. Nature (2013) 1.43
Shelterin-like proteins and Yku inhibit nucleolytic processing of Saccharomyces cerevisiae telomeres. PLoS Genet (2010) 1.42
Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis. J Cell Biol (2008) 1.38
Rif1 supports the function of the CST complex in yeast telomere capping. PLoS Genet (2011) 1.30
The contribution of DNA and chromosome repair deficiencies to the radiosensitivity of ataxia-telangiectasia. Radiat Res (1992) 1.25
Atm inactivation results in aberrant telomere clustering during meiotic prophase. Mol Cell Biol (1999) 1.22
Initial chromosome damage but not DNA damage is greater in ataxia telangiectasia cells. Radiat Res (1992) 1.22
A multifaceted role for ATM in genome maintenance. Expert Rev Mol Med (2003) 1.10
Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice. Proc Natl Acad Sci U S A (2011) 1.03
Functional redundancy between repair factor XLF and damage response mediator 53BP1 in V(D)J recombination and DNA repair. Proc Natl Acad Sci U S A (2012) 1.03
Role of 53BP1 in the regulation of DNA double-strand break repair pathway choice. Radiat Res (2013) 1.00
Opposing roles for 53BP1 during homologous recombination. Nucleic Acids Res (2013) 0.99
Inhibition of telomerase activity enhances hyperthermia-mediated radiosensitization. Cancer Res (2008) 0.97
The role of MOF in the ionizing radiation response is conserved in Drosophila melanogaster. Chromosoma (2011) 0.95
Role of mammalian Rad9 in genomic stability and ionizing radiation response. Cell Cycle (2006) 0.95
Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest. Mol Cell Biol (2013) 0.94
Enhancement of NEIL1 protein-initiated oxidized DNA base excision repair by heterogeneous nuclear ribonucleoprotein U (hnRNP-U) via direct interaction. J Biol Chem (2012) 0.92
Nucleosome dynamics as modular systems that integrate DNA damage and repair. Cold Spring Harb Perspect Biol (2013) 0.89
DNA repair pathway choice--a PTIP of the hat to 53BP1. EMBO Rep (2013) 0.85
Megaprimer-based methodology for deletion of a large fragment within a repetitive polypyrimidine-rich DNA. Mol Biotechnol (2006) 0.76
Interaction of the human DNA glycosylase NEIL1 with proliferating cell nuclear antigen. The potential for replication-associated repair of oxidized bases in mammalian genomes. J Biol Chem (2007) 1.63
MG53-mediated cell membrane repair protects against acute kidney injury. Sci Transl Med (2015) 1.53
The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1. J Biol Chem (2007) 1.38
Activation of ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine. J Biol Chem (2012) 1.30
Preferential repair of oxidized base damage in the transcribed genes of mammalian cells. J Biol Chem (2010) 1.22
Activation of cellular signaling by 8-oxoguanine DNA glycosylase-1-initiated DNA base excision repair. DNA Repair (Amst) (2013) 1.08
Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathways. J Mol Biol (2007) 1.05
RPA physically interacts with the human DNA glycosylase NEIL1 to regulate excision of oxidative DNA base damage in primer-template structures. DNA Repair (Amst) (2010) 1.00
Fen1 mutations that specifically disrupt its interaction with PCNA cause aneuploidy-associated cancer. Cell Res (2011) 0.98
Role of human DNA glycosylase Nei-like 2 (NEIL2) and single strand break repair protein polynucleotide kinase 3'-phosphatase in maintenance of mitochondrial genome. J Biol Chem (2011) 0.98
Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2. DNA Repair (Amst) (2012) 0.92
Antagonism of tumoral prolactin receptor promotes autophagy-related cell death. Cell Rep (2014) 0.86
The interaction between polynucleotide kinase phosphatase and the DNA repair protein XRCC1 is critical for repair of DNA alkylation damage and stable association at DNA damage sites. J Biol Chem (2012) 0.85
New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins. Cell Mol Life Sci (2015) 0.83
A Perspective on Chromosomal Double Strand Break Markers in Mammalian Cells. Jacobs J Radiat Oncol (2015) 0.82
New evidence on α-synuclein and Tau binding to conformation and sequence specific GC* rich DNA: Relevance to neurological disorders. J Pharm Bioallied Sci (2012) 0.81
Recent advances in α-synuclein functions, advanced glycation, and toxicity: implications for Parkinson's disease. Mol Neurobiol (2012) 0.79
Chloride Homeostasis Critically Regulates Synaptic NMDA Receptor Activity in Neuropathic Pain. Cell Rep (2016) 0.79
Role of protein conformational dynamics and DNA integrity in relevance to neuronal cell death in neurodegeneration. Curr Alzheimer Res (2006) 0.76
Evidence of altered DNA integrity in the brain regions of suicidal victims of Bipolar Depression. Indian J Psychiatry (2010) 0.76
Identification and characterization of a basic thaumatin-like protein (TLP 2) as an allergen in sapodilla plum (Manilkara zapota). Mol Nutr Food Res (2013) 0.76