Published in Biomolecules on February 25, 2014
Heavy Metals and Human Health: Mechanistic Insight into Toxicity and Counter Defense System of Antioxidants. Int J Mol Sci (2015) 0.84
Fungal and Prokaryotic Activities in the Marine Subsurface Biosphere at Peru Margin and Canterbury Basin Inferred from RNA-Based Analyses and Microscopy. Front Microbiol (2016) 0.78
Global analysis of protein aggregation in yeast during physiological conditions and arsenite stress. Biol Open (2014) 0.78
Distinct stress conditions result in aggregation of proteins with similar properties. Sci Rep (2016) 0.76
Global Fitness Profiling Identifies Arsenic and Cadmium Tolerance Mechanisms in Fission Yeast. G3 (Bethesda) (2016) 0.75
Arsenate reductase from Thermus thermophilus conjugated to polyethylene glycol-stabilized gold nanospheres allow trace sensing and speciation of arsenic ions. J R Soc Interface (2016) 0.75
Gene expression profiling of microbial activities and interactions in sediments under haloclines of E. Mediterranean deep hypersaline anoxic basins. ISME J (2016) 0.75
Study of conformational changes and protein aggregation of bovine serum albumin in presence of Sb(III) and Sb(V). PLoS One (2017) 0.75
Exposure to selenomethionine causes selenocysteine misincorporation and protein aggregation in Saccharomyces cerevisiae. Sci Rep (2017) 0.75
ER stress causes widespread protein aggregation and prion formation. J Cell Biol (2017) 0.75
Cadmium causes misfolding and aggregation of cytosolic proteins in yeast. Mol Cell Biol (2017) 0.75
Responses of Plant Proteins to Heavy Metal Stress-A Review. Front Plant Sci (2017) 0.75
Drosophila melanogaster Models of Metal-Related Human Diseases and Metal Toxicity. Int J Mol Sci (2017) 0.75
Principles that govern the folding of protein chains. Science (1973) 23.40
Protein degradation and protection against misfolded or damaged proteins. Nature (2003) 10.19
Molecular chaperones in protein folding and proteostasis. Nature (2011) 8.63
HSP104 required for induced thermotolerance. Science (1990) 5.42
Complex formation between metallic cations and proteins, peptides and amino acids. Adv Protein Chem (1956) 5.24
Biological and chemical approaches to diseases of proteostasis deficiency. Annu Rev Biochem (2009) 5.23
Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution. J Mol Med (Berl) (2003) 5.15
Transition metal speciation in the cell: insights from the chemistry of metal ion receptors. Science (2003) 5.12
Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB. Cell (2004) 4.90
Misfolded proteins partition between two distinct quality control compartments. Nature (2008) 4.75
Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway. Nat Cell Biol (2008) 4.68
Intracellular signaling by the unfolded protein response. Annu Rev Cell Dev Biol (2006) 4.55
Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML. Science (2010) 4.52
Biochemical effects of mercury, cadmium, and lead. Annu Rev Biochem (1972) 4.35
Metalloproteins and metal sensing. Nature (2009) 3.97
Hsp104 is required for tolerance to many forms of stress. EMBO J (1992) 3.72
Cellular strategies for controlling protein aggregation. Nat Rev Mol Cell Biol (2010) 3.54
Protein Structure and the Energetics of Protein Stability. Chem Rev (1997) 3.40
Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms. Mol Cell (2010) 3.23
Induction of four proteins in chick embryo cells by sodium arsenite. J Biol Chem (1980) 3.07
Cadmium is a mutagen that acts by inhibiting mismatch repair. Nat Genet (2003) 2.88
Transition series metals and sulfhydryl reagents induce the synthesis of four proteins in eukaryotic cells. Biochim Biophys Acta (1980) 2.75
Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms. Arch Toxicol (2008) 2.75
Sulfur sparing in the yeast proteome in response to sulfur demand. Mol Cell (2002) 2.27
Differential rate of ribosomal protein synthesis in Escherichia coli B/r. J Mol Biol (1974) 2.15
Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide. Proc Natl Acad Sci U S A (2007) 2.11
Glutathione synthesis. Biochim Biophys Acta (2012) 2.11
Antimicrobial activity of metals: mechanisms, molecular targets and applications. Nat Rev Microbiol (2013) 2.04
Essential role of calcineurin in response to endoplasmic reticulum stress. EMBO J (2002) 2.01
Integrating phenotypic and expression profiles to map arsenic-response networks. Genome Biol (2004) 1.90
Life on the edge: a link between gene expression levels and aggregation rates of human proteins. Trends Biochem Sci (2007) 1.88
The native 3D organization of bacterial polysomes. Cell (2009) 1.88
Ribosome and transcript copy numbers, polysome occupancy and enzyme dynamics in Arabidopsis. Mol Syst Biol (2009) 1.86
Untangling amyloid-β, tau, and metals in Alzheimer's disease. ACS Chem Biol (2013) 1.82
Acute cadmium exposure inactivates thioltransferase (Glutaredoxin), inhibits intracellular reduction of protein-glutathionyl-mixed disulfides, and initiates apoptosis. J Biol Chem (2000) 1.76
Proline cis-trans isomerization and protein folding. Biochemistry (2002) 1.76
Heat shock and oxygen radicals stimulate ubiquitin-dependent degradation mainly of newly synthesized proteins. J Cell Biol (2008) 1.71
A proteome analysis of the cadmium response in Saccharomyces cerevisiae. J Biol Chem (2000) 1.68
Systems analysis of transcriptome and proteome in retinoic acid/arsenic trioxide-induced cell differentiation/apoptosis of promyelocytic leukemia. Proc Natl Acad Sci U S A (2005) 1.67
Industrial toxicants and Parkinson's disease. Neurotoxicology (2012) 1.65
The kinetic parameters and energy cost of the Hsp70 chaperone as a polypeptide unfoldase. Nat Chem Biol (2010) 1.59
Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2008) 1.54
Zinc finger proteins as potential targets for toxic metal ions: differential effects on structure and function. Antioxid Redox Signal (2001) 1.48
An arsenite-inducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity. Mol Cell (2006) 1.46
Metal dyshomeostasis and oxidative stress in Alzheimer's disease. Neurochem Int (2012) 1.29
Bioassay of cadmium using a DNA microarray: genome-wide expression patterns of Saccharomyces cerevisiae response to cadmium. Environ Toxicol Chem (2001) 1.29
Arsenic binding to proteins. Chem Rev (2013) 1.28
Global transcriptome and deletome profiles of yeast exposed to transition metals. PLoS Genet (2008) 1.23
Metalloregulatory proteins: metal selectivity and allosteric switching. Biophys Chem (2011) 1.19
How Saccharomyces cerevisiae copes with toxic metals and metalloids. FEMS Microbiol Rev (2010) 1.18
Transition metal homeostasis: from yeast to human disease. Biometals (2011) 1.18
Quantitative transcriptome, proteome, and sulfur metabolite profiling of the Saccharomyces cerevisiae response to arsenite. Physiol Genomics (2007) 1.12
Arsenic(III) species inhibit oxidative protein folding in vitro. Biochemistry (2009) 1.11
Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosis. Cell Calcium (2007) 1.11
Low-level arsenite causes accumulation of ubiquitinated proteins in rabbit renal cortical slices and HEK293 cells. Toxicol Appl Pharmacol (2003) 1.10
Cellular strategies for regulating functional and nonfunctional protein aggregation. Cell Rep (2012) 1.08
Genetic basis of arsenite and cadmium tolerance in Saccharomyces cerevisiae. BMC Genomics (2009) 1.07
Arsenite interferes with protein folding and triggers formation of protein aggregates in yeast. J Cell Sci (2012) 1.06
Heavy metal ions are potent inhibitors of protein folding. Biochem Biophys Res Commun (2008) 1.05
Atypical, bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response. Cell Death Differ (2007) 1.03
Endoplasmic reticulum is a major target of cadmium toxicity in yeast. Mol Microbiol (2010) 1.03
Reactive oxygen species are involved in arsenic trioxide inhibition of pyruvate dehydrogenase activity. Chem Res Toxicol (2003) 1.03
Identification of arsenic-binding proteins in human breast cancer cells. Cancer Lett (2007) 1.01
Cadmium inhibits mismatch repair by blocking the ATPase activity of the MSH2-MSH6 complex. Nucleic Acids Res (2005) 1.00
Rapid, transient induction of ER stress in the liver and kidney after acute exposure to heavy metal: evidence from transgenic sensor mice. FEBS Lett (2007) 0.99
Induction of stress proteins in human endothelial cells by heavy metal ions and heat shock. Am J Physiol (1999) 0.96
Oxidative protein damage causes chromium toxicity in yeast. Microbiology (2005) 0.96
Trivalent arsenic inhibits the functions of chaperonin complex. Genetics (2010) 0.95
Application of the comprehensive set of heterozygous yeast deletion mutants to elucidate the molecular basis of cellular chromium toxicity. Genome Biol (2007) 0.94
Mechanism of Cd2+ toxicity: Cd2+ inhibits photoactivation of Photosystem II by competitive binding to the essential Ca2+ site. Biochim Biophys Acta (2005) 0.94
Mechanisms pertaining to arsenic toxicity. Toxicol Int (2011) 0.94
Role of metal ions in aggregation of intrinsically disordered proteins in neurodegenerative diseases. Metallomics (2011) 0.93
Metal imaging in neurodegenerative diseases. Metallomics (2012) 0.93
Cadmium induces the expression of Grp78, an endoplasmic reticulum molecular chaperone, in LLC-PK1 renal epithelial cells. Environ Health Perspect (2006) 0.92
Characterization of surface-exposed reactive cysteine residues in Saccharomyces cerevisiae. Biochemistry (2010) 0.92
The arsenic exposure hypothesis for Alzheimer disease. Alzheimer Dis Assoc Disord (2014) 0.90
Effect of zinc(II) on the refolding and reactivation of liver alcohol dehydrogenase. Eur J Biochem (1978) 0.89
Changes of heavy metal, metallothionein and heat shock proteins in Sertoli cells induced by cadmium exposure. Toxicol In Vitro (2008) 0.85
Regulation of the arsenic-responsive transcription factor Yap8p involves the ubiquitin-proteasome pathway. J Cell Sci (2007) 0.85
Molecular chaperones and associated cellular clearance mechanisms against toxic protein conformers in Parkinson's disease. Neurodegener Dis (2011) 0.84
Glutathione serves an extracellular defence function to decrease arsenite accumulation and toxicity in yeast. Mol Microbiol (2012) 0.82
The role of metal ions in amyloid formation: general principles from model peptides. Metallomics (2013) 0.81
GFAT as a target molecule of methylmercury toxicity in Saccharomyces cerevisiae. FASEB J (2000) 0.79
Mathematical modelling of arsenic transport, distribution and detoxification processes in yeast. Mol Microbiol (2014) 0.78
Global analysis of protein aggregation in yeast during physiological conditions and arsenite stress. Biol Open (2014) 0.78