The Trade-Off between Dietary Salt and Cardiovascular Disease; A Role for Na/K-ATPase Signaling?

PubWeight™: 0.80‹?›

🔗 View Article (PMC 4101451)

Published in Front Endocrinol (Lausanne) on July 17, 2014

Authors

Joe X Xie1, Anna Pearl Shapiro2, Joseph Isaac Shapiro3

Author Affiliations

1: Department of Medicine, University of Colorado School of Medicine , Aurora, CO , USA.
2: Department of Medicine, University of Toledo College of Medicine , Toledo, OH , USA.
3: Department of Medicine, Joan C. Edwards School of Medicine, Marshall University , Huntington, WV , USA.

Articles cited by this

(truncated to the top 100)

A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N Engl J Med (1997) 19.93

The influence of some cations on an adenosine triphosphatase from peripheral nerves. Biochim Biophys Acta (1957) 9.54

A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats. Life Sci (1981) 6.39

Studies on the efferent mechanism of the sodium diuresis which follows the administration of intravenous saline in the dog. Clin Sci (1961) 5.00

Circulation: overall regulation. Annu Rev Physiol (1972) 3.25

Central role for the cardiotonic steroid marinobufagenin in the pathogenesis of experimental uremic cardiomyopathy. Hypertension (2006) 2.64

Na(+)/K(+)-ATPase as a signal transducer. Eur J Biochem (2002) 2.39

Chromosomal localization of human Na+, K+-ATPase alpha- and beta-subunit genes. Genomics (1988) 2.20

Identification and characterization of a ouabain-like compound from human plasma. Proc Natl Acad Sci U S A (1991) 2.20

Cardiac glycoside downregulates NHE3 activity and expression in LLC-PK1 cells. Am J Physiol Renal Physiol (2005) 2.18

Endogenous cardiotonic steroids: physiology, pharmacology, and novel therapeutic targets. Pharmacol Rev (2009) 2.17

No endogenous ouabain is detectable in human plasma by ultra-sensitive UPLC-MS/MS. Clin Chim Acta (2014) 2.16

Endogenous digitalis-like substance in plasma of volume-expanded dogs. Nature (1980) 2.02

Binding of Src to Na+/K+-ATPase forms a functional signaling complex. Mol Biol Cell (2005) 1.92

Fli-1 inhibits collagen type I production in dermal fibroblasts via an Sp1-dependent pathway. J Biol Chem (2001) 1.80

Investigations on the effect of some local anaesthetics and other amines on the active transport of sodium through the isolated short-circuited frog skin. Biochim Biophys Acta (1959) 1.78

Ouabain assembles signaling cascades through the caveolar Na+/K+-ATPase. J Biol Chem (2004) 1.71

The Na,K-ATPase. J Bioenerg Biomembr (1992) 1.70

Identification of a pool of non-pumping Na/K-ATPase. J Biol Chem (2007) 1.69

Ouabain-Sensitive alpha1 Na,K-ATPase enhances natriuretic response to saline load. J Am Soc Nephrol (2008) 1.68

Ouabain triggers preconditioning through activation of the Na+,K+-ATPase signaling cascade in rat hearts. Cardiovasc Res (2006) 1.67

Involvement of Src and epidermal growth factor receptor in the signal-transducing function of Na+/K+-ATPase. J Biol Chem (2000) 1.63

Ouabain interaction with cardiac Na+/K+-ATPase initiates signal cascades independent of changes in intracellular Na+ and Ca2+ concentrations. J Biol Chem (2000) 1.60

Physiological roles of endogenous ouabain in normal rats. Am J Physiol Heart Circ Physiol (2009) 1.58

Intracellular reactive oxygen species mediate the linkage of Na+/K+-ATPase to hypertrophy and its marker genes in cardiac myocytes. J Biol Chem (1999) 1.52

Src-mediated inter-receptor cross-talk between the Na+/K+-ATPase and the epidermal growth factor receptor relays the signal from ouabain to mitogen-activated protein kinases. J Biol Chem (2002) 1.51

The alpha 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca exchanger in heart. J Biol Chem (2004) 1.43

Digitalis. Circulation (1999) 1.43

Marinobufagenin stimulates fibroblast collagen production and causes fibrosis in experimental uremic cardiomyopathy. Hypertension (2006) 1.42

Do putative endogenous digitalis-like factors have a physiological role? Hypertension (1994) 1.42

Ouabain induces endocytosis of plasmalemmal Na/K-ATPase in LLC-PK1 cells by a clathrin-dependent mechanism. Kidney Int (2004) 1.37

Na/K-ATPase tethers phospholipase C and IP3 receptor into a calcium-regulatory complex. Mol Biol Cell (2005) 1.36

Endogenous and exogenous cardiac glycosides and their mechanisms of action. Am J Cardiovasc Drugs (2007) 1.36

Endogenous digitalis: pathophysiologic roles and therapeutic applications. Nat Clin Pract Nephrol (2008) 1.35

The effect of dialysates and ultrafiltrates of plasma of saline-loaded dogs on toad bladder sodium transport. J Clin Invest (1970) 1.33

The Na,K-ATPase receptor complex: its organization and membership. Cell Biochem Biophys (2006) 1.32

Partial nephrectomy as a model for uremic cardiomyopathy in the mouse. Am J Physiol Renal Physiol (2007) 1.31

The presence of a natriuretic factor in urine of patients with chronic uremia. The absence of the factor in nephrotic uremic patients. J Clin Invest (1974) 1.31

Physiological role of the alpha1- and alpha2-isoforms of the Na+-K+-ATPase and biological significance of their cardiac glycoside binding site. Am J Physiol Regul Integr Comp Physiol (2006) 1.30

Marinobufagenin induces increases in procollagen expression in a process involving protein kinase C and Fli-1: implications for uremic cardiomyopathy. Am J Physiol Renal Physiol (2009) 1.23

On the pathogenesis of the uremic state. An exposition of the "trade-off hypothesis". N Engl J Med (1972) 1.20

Ouabain-induced endocytosis of the plasmalemmal Na/K-ATPase in LLC-PK1 cells requires caveolin-1. Kidney Int (2005) 1.19

The INTERSALT study: an addition to the evidence on salt and blood pressure, and some implications. J Hum Hypertens (1989) 1.14

Salt loading induces redistribution of the plasmalemmal Na/K-ATPase in proximal tubule cells. Kidney Int (2005) 1.14

A novel endogenous digitalis, telocinobufagin, exhibits elevated plasma levels in patients with terminal renal failure. Clin Biochem (2005) 1.13

Nobel Lecture. The identification of the sodium pump. Biosci Rep (1998) 1.12

The Na-K-ATPase and calcium-signaling microdomains. Physiology (Bethesda) (2008) 1.11

Monoclonal antibody against marinobufagenin reverses cardiac fibrosis in rats with chronic renal failure. Am J Hypertens (2012) 1.11

Involvement of mitogen-activated protein kinases and reactive oxygen species in the inotropic action of ouabain on cardiac myocytes. A potential role for mitochondrial K(ATP) channels. Mol Cell Biochem (2003) 1.10

The interrelationships of the cardiovascular, renal and electrolyte effects of intravenous digoxin in congestive heart failure. J Clin Invest (1951) 1.05

Circulating inhibitor of sodium-potassium-activated adenosine triphosphatase after expansion of extracellular fluid volume in rats. Clin Sci Mol Med (1977) 1.04

Rostafuroxin: an ouabain antagonist that corrects renal and vascular Na+-K+- ATPase alterations in ouabain and adducin-dependent hypertension. Am J Physiol Regul Integr Comp Physiol (2006) 1.03

The cardiotonic steroid hormone marinobufagenin induces renal fibrosis: implication of epithelial-to-mesenchymal transition. Am J Physiol Renal Physiol (2009) 1.02

Canrenone as a partial agonist at the digitalis receptor site of sodium-potassium-activated adenosine triphosphatase. J Pharmacol Exp Ther (1981) 1.00

In vitro and in vivo protective effect of atriopeptin III on ischemic acute renal failure. J Clin Invest (1987) 1.00

Effects of cardiac glycosides on sodium pump expression and function in LLC-PK1 and MDCK cells. Kidney Int (2002) 1.00

Spironolactone attenuates experimental uremic cardiomyopathy by antagonizing marinobufagenin. Hypertension (2009) 0.99

Regulation of apical NHE3 trafficking by ouabain-induced activation of the basolateral Na+-K+-ATPase receptor complex. Am J Physiol Cell Physiol (2007) 0.99

Effect of green tea extract on cardiac hypertrophy following 5/6 nephrectomy in the rat. Kidney Int (2003) 0.98

A digoxin-like immunoreactive substance in preeclampsia. Am J Obstet Gynecol (1984) 0.98

Cardionatrin I - a novel heart peptide with potent diuretic and natriuretic properties. Life Sci (1983) 0.98

Impairment of Na/K-ATPase signaling in renal proximal tubule contributes to Dahl salt-sensitive hypertension. J Biol Chem (2011) 0.98

Na/K-ATPase mimetic pNaKtide peptide inhibits the growth of human cancer cells. J Biol Chem (2011) 0.97

The Na/K-ATPase-mediated signal transduction as a target for new drug development. Front Biosci (2005) 0.97

Determination of total (Na+ + K+)-ATPase activity of isolated or cultured cells. Anal Biochem (1989) 0.97

On the biology of sodium excretion: The search for a natriuretic hormone. Yale J Biol Med (1975) 0.95

Endogenous cardiotonic steroids in chronic renal failure. Nephrol Dial Transplant (2011) 0.95

Regulation of sodium pump endocytosis by cardiotonic steroids: Molecular mechanisms and physiological implications. Pathophysiology (2007) 0.95

Ouabain interaction with cardiac Na/K-ATPase reveals that the enzyme can act as a pump and as a signal transducer. Cell Mol Biol (Noisy-le-grand) (2001) 0.95

Endogenous cardiotonic steroids and salt-sensitive hypertension. Biochim Biophys Acta (2010) 0.94

Characterization of digitalis-like factors in human plasma. Interactions with NaK-ATPase and cross-reactivity with cardiac glycoside-specific antibodies. J Biol Chem (1985) 0.94

Regulation of inositol 1,4,5-trisphosphate receptor-mediated calcium release by the Na/K-ATPase in cultured renal epithelial cells. J Biol Chem (2007) 0.91

Rostafuroxin: an ouabain-inhibitor counteracting specific forms of hypertension. Biochim Biophys Acta (2010) 0.91

Absence of natriuretic response to acute hypotonic intravascular volume expansion in dogs. Clin Sci (1968) 0.90

Involvement of reactive oxygen species in a feed-forward mechanism of Na/K-ATPase-mediated signaling transduction. J Biol Chem (2013) 0.89

Effects of rat atrial extract on sodium transport and blood pressure in the rat. Proc Soc Exp Biol Med (1984) 0.87

Digoxin- and digitoxin-like immunoreactive substances in amniotic fluid, cord blood, and serum of neonates. Pediatr Res (1986) 0.84

The identification of the sodium pump. Biosci Rep (2005) 0.84

Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive alpha1 Na+-K+-ATPase. Am J Physiol Heart Circ Physiol (2009) 0.84

Passive immunization against marinobufagenin attenuates renal fibrosis and improves renal function in experimental renal disease. Am J Hypertens (2013) 0.84

Body fluid volume regulation in health and disease. Adv Intern Med (1994) 0.83

Effects of oxytocin antagonists on the saluresis accompanying carotid occlusion. Am J Physiol (1966) 0.82

Salt and hypertension. Nephrology (Carlton) (2010) 0.82

Progress in isolation and purification of an inhibitor of sodium transport obtained from dog urine. Kidney Int (1982) 0.81

Sodium intake and essential hypertension. Hypertension (1982) 0.80

Effects of uremic serum on isolated cardiac myocyte calcium cycling and contractile function. Kidney Int (2001) 0.79

Physiologic rationale for multiple sodium pump isoforms. Differential regulation of alpha 1 vs alpha 2 by ionic stimuli. Ann N Y Acad Sci (1992) 0.79

Identification of hydroxyxanthones as Na/K-ATPase ligands. Mol Pharmacol (2010) 0.78

Molecular insights into uremic cardiomyopathy: cardiotonic steroids and Na/K ATPase signaling. Cell Mol Biol (Noisy-le-grand) (2006) 0.78

Interference of digoxin-like immunoreactive substances with three digoxin immunoassays in patients with various degrees of renal function. Clin Pharm (1986) 0.77

Atrial natriuretic factor. Adv Intern Med (1987) 0.77

Evidence for a hormone other than aldosterone which controls urinary sodium excretion. Adv Nephrol Necker Hosp (1971) 0.77

Activation of Na+/K(+)-ATPase by fatty acids, acylglycerols, and related amphiphiles: structure-activity relationship. Biochim Biophys Acta (1996) 0.77

Inter and intra laboratory variation of digoxin radioimmunoassay in Sweden. Acta Pharmacol Toxicol (Copenh) (1979) 0.76

Is endogenous ouabain a physiological regulator of cardiovascular and renal function? Am J Physiol Heart Circ Physiol (2009) 0.76

Precision of digoxin radioimmunoassays and matrix effects: four kits compared. Clin Biochem (1981) 0.76

The effect of acute extracellular fluid volume expansion and acute haemorrhage on plasma antidiuretic hormone and oxytocin levels in dogs. J Physiol (1968) 0.76

Excretion of artifactual endogenous digitalis-like factors. Am J Physiol (1986) 0.76

The problems of digitalis therapy from the viewpoint of serum concentration with special reference to the sampling time, to the overlapping range of serum concentration where intoxicated and non-intoxicated patients are located and to atrial fibrillation. Jpn Circ J (1986) 0.76

Hormonal changes and transport adaptation in chronic renal failure: the possible role of a natriuretic hormone. Biochem Soc Trans (1978) 0.75