Published in Clin Drug Investig on November 01, 2014
Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med (2009) 39.97
Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med (2008) 28.42
Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med (2011) 23.50
A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee. Lancet (1996) 16.32
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med (2013) 8.76
Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack. Lancet (2007) 7.27
Short-term prognosis after emergency department diagnosis of TIA. JAMA (2000) 5.00
Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial. Lancet Neurol (2007) 3.72
Prevention and treatment of thromboembolic and ischemic complications associated with endovascular procedures: Part II--Clinical aspects and recommendations. Neurosurgery (2000) 1.54
Recent advances in management of transient ischaemic attacks and minor ischaemic strokes. Lancet Neurol (2006) 1.33
Improving the quality of consent to randomised controlled trials by using continuous consent and clinician training in the consent process. J Med Ethics (2006) 1.30
Intravenous heparin started within the first 3 hours after onset of symptoms as a treatment for acute nonlacunar hemispheric cerebral infarctions. Stroke (2005) 1.19
Importance of pharmacokinetic profile and variability as determinants of dose and response to dabigatran, rivaroxaban, and apixaban. Can J Cardiol (2013) 0.89
EMAN2: an extensible image processing suite for electron microscopy. J Struct Biol (2006) 14.70
Nanoparticle-mediated cellular response is size-dependent. Nat Nanotechnol (2008) 8.23
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome. Cell Metab (2006) 4.64
Outcome of the first electron microscopy validation task force meeting. Structure (2012) 4.35
Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra. Nature (2008) 3.92
Multistage nanoparticle delivery system for deep penetration into tumor tissue. Proc Natl Acad Sci U S A (2011) 3.34
A comparative anatomic study of a modified temporal-occipital transtentorial transpetrosal-ridge approach and a transpetrosal presigmoid approach. World Neurosurg (2011) 3.30
Direct charging of tRNA(CUA) with pyrrolysine in vitro and in vivo. Nature (2004) 2.69
Common ancestry of herpesviruses and tailed DNA bacteriophages. J Virol (2005) 2.60
Cryo-EM asymmetric reconstruction of bacteriophage P22 reveals organization of its DNA packaging and infecting machinery. Structure (2006) 2.26
Electron cryomicroscopy of biological machines at subnanometer resolution. Structure (2005) 2.15
The prevalence and burden of primary headaches in China: a population-based door-to-door survey. Headache (2012) 2.04
Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus. Proc Natl Acad Sci U S A (2011) 2.03
Averaging tens to hundreds of icosahedral particle images to resolve protein secondary structure elements using a Multi-Path Simulated Annealing optimization algorithm. J Struct Biol (2007) 1.90
Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse. Nat Med (2006) 1.82
Noroviral P particle: structure, function and applications in virus-host interaction. Virology (2008) 1.75
A 9 angstroms single particle reconstruction from CCD captured images on a 200 kV electron cryomicroscope. J Struct Biol (2004) 1.70
The burden of headache in China: validation of diagnostic questionnaire for a population-based survey. J Headache Pain (2011) 1.67
Biodegradable quantum dot nanocomposites enable live cell labeling and imaging of cytoplasmic targets. Nano Lett (2008) 1.64
The mRNA expression of SATB1 and SATB2 in human breast cancer. Cancer Cell Int (2009) 1.62
Compact biocompatible quantum dots via RAFT-mediated synthesis of imidazole-based random copolymer ligand. J Am Chem Soc (2010) 1.60
Conformational flexibility facilitates self-assembly of complex DNA nanostructures. Proc Natl Acad Sci U S A (2008) 1.60
A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties. J Pharmacol Exp Ther (2004) 1.58
Rosuvastatin attenuates the elevation in blood pressure induced by overexpression of human C-reactive protein. Hypertens Res (2011) 1.50
Sevoflurane preconditioning improves mitochondrial function and long-term neurologic sequelae after transient cerebral ischemia: role of mitochondrial permeability transition. Crit Care Med (2012) 1.48
Rotavirus architecture at subnanometer resolution. J Virol (2008) 1.48
Mediation of multiple pathways regulating cell proliferation, migration, and apoptosis in the human malignant glioma cell line U87MG via unphosphorylated STAT1: laboratory investigation. J Neurosurg (2013) 1.44
Blockade of constitutively activated Janus kinase/signal transducer and activator of transcription-3 pathway inhibits growth of human pancreatic cancer. Cancer Lett (2003) 1.42
Expression of snail in pancreatic cancer promotes metastasis and chemoresistance. J Surg Res (2007) 1.40
Value of myocardial regional perfusion on long-term function in collateral-dependent myocardium. South Med J (2008) 1.40
Norovirus P particle, a novel platform for vaccine development and antibody production. J Virol (2010) 1.39
Genome sequence, structural proteins, and capsid organization of the cyanophage Syn5: a "horned" bacteriophage of marine synechococcus. J Mol Biol (2007) 1.37
Superparamagnetic iron oxide nanoparticles as MRI contrast agents for non-invasive stem cell labeling and tracking. Theranostics (2013) 1.33
Zinc biofortification of cereals: rice differs from wheat and barley. Trends Plant Sci (2009) 1.30
Obstructive sleep apnea and risk of cardiovascular disease and all-cause mortality: a meta-analysis of prospective cohort studies. Int J Cardiol (2013) 1.29
The first potent and selective non-imidazole human histamine H4 receptor antagonists. J Med Chem (2003) 1.28
Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN. J Neurosci (2004) 1.28
Deriving folds of macromolecular complexes through electron cryomicroscopy and bioinformatics approaches. Curr Opin Struct Biol (2002) 1.27
The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor. Proc Natl Acad Sci U S A (2006) 1.26
Overexpression of high-mobility group box 1 correlates with tumor progression and poor prognosis in human colorectal carcinoma. J Cancer Res Clin Oncol (2009) 1.26
Cryo-EM structure of a novel calicivirus, Tulane virus. PLoS One (2013) 1.26
Terminal modifications of norovirus P domain resulted in a new type of subviral particles, the small P particles. Virology (2010) 1.25
Single particle cryo-electron microscopy and 3-D reconstruction of viruses. Methods Mol Biol (2014) 1.23
Neuroprotective effects of ginsenoside Rd against oxygen-glucose deprivation in cultured hippocampal neurons. Neurosci Res (2009) 1.23
Reactivity and chemical synthesis of L-pyrrolysine- the 22(nd) genetically encoded amino acid. Chem Biol (2004) 1.19
Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells. Proc Natl Acad Sci U S A (2013) 1.19
Breast cancer resistance protein (ABCG2) determines distribution of genistein phase II metabolites: reevaluation of the roles of ABCG2 in the disposition of genistein. Drug Metab Dispos (2012) 1.19
Visualization of uncorrelated, tandem symmetry mismatches in the internal genome packaging apparatus of bacteriophage T7. Proc Natl Acad Sci U S A (2013) 1.19
Persistence of side population cells with high drug efflux capacity in pancreatic cancer. World J Gastroenterol (2008) 1.18
Surface-plasmon-coupled emission of quantum dots. J Phys Chem B (2005) 1.17
'First-in-man': characterising the mechanosensitivity of human colonic afferents. Gut (2010) 1.17
A meta-analysis of gemcitabine containing chemotherapy for locally advanced and metastatic pancreatic adenocarcinoma. J Hematol Oncol (2011) 1.15
Diagnostic value of multislice computed tomography angiography in coronary artery disease: a meta-analysis. Eur J Radiol (2006) 1.13
Ginsenoside Rd attenuates early oxidative damage and sequential inflammatory response after transient focal ischemia in rats. Neurochem Int (2010) 1.11
Asymmetric [3+2] cycloadditions of allenoates and dual activated olefins catalyzed by simple bifunctional N-acyl aminophosphines. Angew Chem Int Ed Engl (2010) 1.10
Validated near-atomic resolution structure of bacteriophage epsilon15 derived from cryo-EM and modeling. Proc Natl Acad Sci U S A (2013) 1.10
Specificity of pyrrolysyl-tRNA synthetase for pyrrolysine and pyrrolysine analogs. J Mol Biol (2008) 1.08
Ab initio modeling of the herpesvirus VP26 core domain assessed by CryoEM density. PLoS Comput Biol (2006) 1.08
Molecular cloning and promoter analysis of downregulated in adenoma (DRA). Am J Physiol Gastrointest Liver Physiol (2007) 1.07
Ginsenoside Rd attenuates redox imbalance and improves stroke outcome after focal cerebral ischemia in aged mice. Neuropharmacology (2011) 1.07
Local delivery of anti-monocyte chemoattractant protein-1 by gene-eluting stents attenuates in-stent stenosis in rabbits and monkeys. Arterioscler Thromb Vasc Biol (2007) 1.07
Body mass index and migraine: a survey of the Chinese adult population. J Headache Pain (2012) 1.06
microRNA-181a represses ox-LDL-stimulated inflammatory response in dendritic cell by targeting c-Fos. J Lipid Res (2012) 1.05
Osteopontin expression profiles predict pathological and clinical outcome in breast cancer. Anticancer Res (2009) 1.05
Architecture of the herpes simplex virus major capsid protein derived from structural bioinformatics. J Mol Biol (2003) 1.05
The skeletal muscle Ca2+ release channel has an oxidoreductase-like domain. Proc Natl Acad Sci U S A (2002) 1.04
Headache yesterday in China: a new approach to estimating the burden of headache, applied in a general-population survey in China. Cephalalgia (2013) 1.04
Meta-modeling soil organic carbon sequestration potential and its application at regional scale. Ecol Appl (2013) 1.03
Nonlinear optical microscopy for histology of fresh normal and cancerous pancreatic tissues. PLoS One (2012) 1.02
The accuracy of survival time prediction for patients with glioma is improved by measuring mitotic spindle checkpoint gene expression. PLoS One (2011) 1.02
Localization of orexin-1 receptors to vagal afferent neurons in the rat and humans. Gastroenterology (2003) 1.02
Symmetry controls the face geometry of DNA polyhedra. J Am Chem Soc (2009) 1.02
Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway. Toxicology (2012) 1.01
Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module. Proc Natl Acad Sci U S A (2006) 1.01
Pharmacokinetics and tissue distribution of PGG-paclitaxel, a novel macromolecular formulation of paclitaxel, in nu/nu mice bearing NCI-460 lung cancer xenografts. Cancer Chemother Pharmacol (2009) 1.01
Cancer stem-like cells enriched in Panc-1 spheres possess increased migration ability and resistance to gemcitabine. Int J Mol Sci (2011) 1.00
Inhibition of RIP and c-FLIP enhances TRAIL-induced apoptosis in pancreatic cancer cells. Cell Signal (2007) 1.00
Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel. J Control Release (2009) 0.99
Preclinical efficacy studies of a novel nanoparticle-based formulation of paclitaxel that out-performs Abraxane. Cancer Chemother Pharmacol (2009) 0.99
Interprotomer motion-transmission mechanism for the hexameric AAA ATPase p97. Proc Natl Acad Sci U S A (2012) 0.99
Magnetic responsive hydroxyapatite composite scaffolds construction for bone defect reparation. Int J Nanomedicine (2012) 0.98
The serotonin transporter gene polymorphism (5-HTTLPR) and irritable bowel syndrome: a meta-analysis of 25 studies. BMC Gastroenterol (2014) 0.98
Sodium tanshinone IIA sulfonate mediates electron transfer reaction in rat heart mitochondria. Biochem Pharmacol (2003) 0.98
Stimulation of proteinase-activated receptor 2 excites jejunal afferent nerves in anaesthetised rats. J Physiol (2003) 0.97
Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. J Am Chem Soc (2006) 0.97
Fast rotational matching of single-particle images. J Struct Biol (2005) 0.96
Wnt5a as an effector of TGFβ in mammary development and cancer. J Mammary Gland Biol Neoplasia (2011) 0.96
Effects of berberine on potassium currents in acutely isolated CA1 pyramidal neurons of rat hippocampus. Brain Res (2004) 0.96
A novel calcium phosphate ceramic-magnetic nanoparticle composite as a potential bone substitute. Biomed Mater (2010) 0.96
The neuroprotection of liraglutide on Alzheimer-like learning and memory impairment by modulating the hyperphosphorylation of tau and neurofilament proteins and insulin signaling pathways in mice. J Alzheimers Dis (2013) 0.96
Hepatocyte caspase-8 is an essential modulator of steatohepatitis in rodents. Hepatology (2013) 0.95
Catheter-based adenovirus-mediated anti-monocyte chemoattractant gene therapy attenuates in-stent neointima formation in cynomolgus monkeys. Atherosclerosis (2006) 0.95
Ginsenoside rd in experimental stroke: superior neuroprotective efficacy with a wide therapeutic window. Neurotherapeutics (2011) 0.95