Published in J Immunol on May 01, 1989
Structure of the T cell antigen receptor (TCR): two CD3 epsilon subunits in a functional TCR/CD3 complex. J Exp Med (1991) 1.47
Surface expression of a T cell receptor beta (TCR-beta) chain in the absence of TCR-alpha, -delta, and -gamma proteins. J Exp Med (1991) 1.39
Stoichiometry of the T cell antigen receptor (TCR) complex: each TCR/CD3 complex contains one TCR alpha, one TCR beta, and two CD3 epsilon chains. J Exp Med (1994) 1.28
Interleukin 4 expressed in situ selectively alters thymocyte development. J Exp Med (1991) 1.25
Abnormal T cell responses to bacterial superantigens in Behçet's disease (BD). Clin Exp Immunol (1998) 1.14
Functional cleavage of the common cytokine receptor gamma chain (gammac) by calpain. Proc Natl Acad Sci U S A (1997) 1.09
Priming of immature thymocytes to CD3-mediated apoptosis by infection with murine cytomegalovirus. J Virol (1994) 1.07
Developmental regulation of thymocyte susceptibility to deletion by "self"-peptide. J Exp Med (1992) 0.97
Physical dissociation of the TCR-CD3 complex accompanies receptor ligation. J Exp Med (1995) 0.95
Interleukin 2-mediated uncoupling of T cell receptor alpha/beta from CD3 signaling. J Exp Med (1998) 0.86
Development and function of T cells in T cell antigen receptor/CD3 zeta knockout mice reconstituted with Fc epsilon RI gamma. Proc Natl Acad Sci U S A (1997) 0.85
T-cell receptor-bearing cells from athymic nude rats respond to alloantigen in vitro but are defective in vivo. Immunology (1991) 0.82
Differential effect on TCR:CD3 stimulation of a 90-kD glycoprotein (gp90/Mac-2BP), a member of the scavenger receptor cysteine-rich domain protein family. Clin Exp Immunol (1998) 0.79
Modulation of murine host-versus-graft disease by anti-CD3 monoclonal antibody. Clin Exp Immunol (1991) 0.75
Evidence for aberrant regulation of MAP kinase signal transduction pathway in peripheral blood mononuclear cells in patients with active celiac disease. Dig Dis Sci (2008) 0.75
T cell tolerance by clonal elimination in the thymus. Cell (1987) 13.83
Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition. J Exp Med (1981) 12.03
Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors. J Immunol (1989) 8.19
Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. Science (1990) 8.17
The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J Exp Med (1983) 7.55
Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci U S A (1989) 7.48
The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice. Cell (1989) 7.02
Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing. J Exp Med (1983) 6.97
Control of homeostasis of CD8+ memory T cells by opposing cytokines. Science (2000) 6.22
Superantigens: mechanism of T-cell stimulation and role in immune responses. Annu Rev Immunol (1991) 5.71
V beta-specific stimulation of human T cells by staphylococcal toxins. Science (1989) 5.34
The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens. Nature (1988) 4.43
The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes. J Immunol (1994) 4.37
The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J Exp Med (1984) 4.29
T cells compete for access to antigen-bearing antigen-presenting cells. J Exp Med (2000) 4.16
Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes. Immunity (1998) 4.15
Interleukin-induced increase in Ia expression by normal mouse B cells. J Exp Med (1984) 4.14
A T cell receptor V beta segment that imparts reactivity to a class II major histocompatibility complex product. Cell (1987) 4.09
Several common HLA-DR types share largely overlapping peptide binding repertoires. J Immunol (1998) 3.95
Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo. Cell Immunol (2001) 3.91
Superantigens and their potential role in human disease. Adv Immunol (1993) 3.88
Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules. Cell (1993) 3.80
Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen. J Immunol (1984) 3.72
Evidence for the effects of a superantigen in rheumatoid arthritis. Science (1991) 3.71
The role of the T cell receptor in positive and negative selection of developing T cells. Science (1990) 3.64
The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product. J Exp Med (1983) 3.54
A superantigen encoded in the open reading frame of the 3' long terminal repeat of mouse mammary tumour virus. Nature (1991) 3.47
Antigen presentation by Ia+ B cell hybridomas to H-2-restricted T cell hybridomas. Proc Natl Acad Sci U S A (1982) 3.41
B cell helper factors. I. Requirement for both interleukin 2 and another 40,000 mol wt factor. J Exp Med (1981) 3.40
Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gamma RIIB1. Science (1995) 3.24
Superantigens interact with MHC class II molecules outside of the antigen groove. Cell (1990) 3.20
An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proc Natl Acad Sci U S A (1999) 3.15
The repertoire of T cells shaped by a single MHC/peptide ligand. Cell (1996) 3.04
Concanavalin A-inducible, interleukin-2-producing T cell hybridoma. J Exp Med (1980) 3.02
Production of soluble MHC class II proteins with covalently bound single peptides. Nature (1994) 2.98
Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit. Science (1994) 2.98
Primary structure of human T-cell receptor alpha-chain. Nature (1985) 2.93
Development of high potency universal DR-restricted helper epitopes by modification of high affinity DR-blocking peptides. Immunity (1994) 2.90
Antigen presentation by supported planar membranes containing affinity-purified I-Ad. Proc Natl Acad Sci U S A (1984) 2.80
Two better cell lines for making hybridomas expressing specific T cell receptors. J Immunol (1989) 2.78
Immunological adjuvants promote activated T cell survival via induction of Bcl-3. Nat Immunol (2001) 2.76
Cytokine-induced survival of activated T cells in vitro and in vivo. Proc Natl Acad Sci U S A (1998) 2.71
Selective expansion of T cells expressing V beta 2 in toxic shock syndrome. J Exp Med (1990) 2.71
The small subunit of HL-A antigens is beta 2-microglobulin. J Exp Med (1973) 2.68
The major histocompatibility complex-restricted antigen receptor on T cells: distribution on thymus and peripheral T cells. Cell (1984) 2.64
Residues of the variable region of the T-cell-receptor beta-chain that interact with S. aureus toxin superantigens. Nature (1990) 2.60
The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas. Cell (1983) 2.58
Structures of an MHC class II molecule with covalently bound single peptides. Science (1996) 2.58
Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med (1983) 2.56
Identification of the region of T cell receptor beta chain that interacts with the self-superantigen MIs-1a. Cell (1990) 2.42
The B cell antigen receptor complex: association of Ig-alpha and Ig-beta with distinct cytoplasmic effectors. Science (1992) 2.41
Mutations defining functional regions of the superantigen staphylococcal enterotoxin B. J Exp Med (1992) 2.38
Thymus-derived (T) cell immunoglobulins. Presence of a receptor site for IgG and absence of large amounts of "buried" Ig determinants on T cells. J Exp Med (1972) 2.35
HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells. J Exp Med (1990) 2.30
Lipopolysaccharide interferes with the induction of peripheral T cell death. Immunity (1995) 2.29
Antigen-specific and nonspecific mediators of T cell/B cell cooperation. I. Evidence for their production by different T cells. J Immunol (1975) 2.26
Antigen-specific. I region-restricted interactions in vitro between tumor cell lines and T cell hybridomas. J Immunol (1982) 2.26
Superantigens: bacterial and viral proteins that manipulate the immune system. Annu Rev Cell Biol (1993) 2.26
B lymphocyte antigen receptors (mIg) are non-covalently associated with a disulfide linked, inducibly phosphorylated glycoprotein complex. EMBO J (1990) 2.24
Molecular mechanisms of transmembrane signaling in B lymphocytes. Annu Rev Immunol (1987) 2.22
Use of I region-restricted, antigen-specific T cell hybridomas to produce idiotypically specific anti-receptor antibodies. J Immunol (1983) 2.19
Resident pulmonary lymphocytes expressing the gamma/delta T-cell receptor. Nature (1989) 2.16
Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4. J Exp Med (1997) 2.15
The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma. J Exp Med (1984) 2.13
Rearrangement of T-cell receptor beta-chain genes during T-cell development. Proc Natl Acad Sci U S A (1985) 2.13
Gene transfer of H-2 class II genes: antigen presentation by mouse fibroblast and hamster B-cell lines. Cell (1984) 2.12
Compartmentalization of MHC class II gene expression in transgenic mice. Cell (1988) 2.08
Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus type 16 E6 and E7 proteins. J Immunol (1994) 2.07
CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection. J Exp Med (1999) 2.04
The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. Cell (1983) 2.04
The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity. J Exp Med (1983) 2.03
In vivo administration of monoclonal antibodies to the CD3 T cell receptor complex induces cell death (apoptosis) in immature thymocytes. J Immunol (1991) 2.00
The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression. J Exp Med (1978) 2.00
Unexpected expansions of CD8-bearing cells in old mice. J Immunol (1993) 1.98
The T cell receptor: the alpha and beta chains define idiotype, and antigen and MHC specificity. Cell (1985) 1.96
Ia binding ligands and cAMP stimulate nuclear translocation of PKC in B lymphocytes. Nature (1987) 1.93