Published in Nature on February 20, 1985
Analysis of cDNA clones specific for human T cells and the alpha and beta chains of the T-cell receptor heterodimer from a human T-cell line. Proc Natl Acad Sci U S A (1985) 3.41
Evolutionarily conserved amino acids that control TCR-MHC interaction. Annu Rev Immunol (2008) 2.79
Expression of T3 in association with a molecule distinct from the T-cell antigen receptor heterodimer. Proc Natl Acad Sci U S A (1986) 2.73
A T-cell-specific transcriptional enhancer element 3' of C alpha in the human T-cell receptor alpha locus. Proc Natl Acad Sci U S A (1989) 2.51
Complex rearrangements within the human J delta-C delta/J alpha-C alpha locus and aberrant recombination between J alpha segments. EMBO J (1988) 2.05
Endocytosis and recycling of the T3-T cell receptor complex. The role of T3 phosphorylation. J Exp Med (1987) 1.80
Sequences and repertoire of human T cell receptor alpha chain variable region genes in mature T lymphocytes. J Exp Med (1986) 1.75
Cloning of the gene encoding the delta subunit of the human T-cell receptor reveals its physical organization within the alpha-subunit locus and its involvement in chromosome translocations in T-cell malignancy. Proc Natl Acad Sci U S A (1988) 1.74
Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody. EMBO J (1998) 1.74
Diversity and structure of human T-cell receptor alpha-chain variable region genes. Proc Natl Acad Sci U S A (1987) 1.69
The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia. EMBO J (1985) 1.64
Sequences and diversity of human T cell receptor beta chain variable region genes. J Exp Med (1986) 1.62
Rearrangement and expression of the alpha, beta, and gamma chain T cell receptor genes in human thymic leukemia cells and functional T cells. J Exp Med (1986) 1.62
Constitutive endocytosis of HLA class I antigens requires a specific portion of the intracytoplasmic tail that shares structural features with other endocytosed molecules. Proc Natl Acad Sci U S A (1989) 1.54
Sequence and organization of the diversity, joining, and constant region genes of the human T-cell delta-chain locus. Proc Natl Acad Sci U S A (1988) 1.53
Generation of diversity in T cell receptor repertoire specific for pigeon cytochrome c. J Exp Med (1987) 1.52
Sequence and evolution of the human T-cell antigen receptor beta-chain genes. Proc Natl Acad Sci U S A (1985) 1.50
T-cell receptor V alpha and C alpha alleles associated with multiple and myasthenia gravis. Proc Natl Acad Sci U S A (1989) 1.47
Genes encoding the T-cell receptor alpha and beta subunits are transcribed in an ordered manner during intrathymic ontogeny. Proc Natl Acad Sci U S A (1985) 1.47
Preferential T-cell receptor beta-chain variable gene use in myelin basic protein-reactive T-cell clones from patients with multiple sclerosis. Proc Natl Acad Sci U S A (1991) 1.47
Human T cell receptor V beta gene polymorphism. J Exp Med (1987) 1.46
Genomic organization of the human T-cell antigen-receptor alpha/delta locus. Proc Natl Acad Sci U S A (1988) 1.41
Hybrid hybridoma producing a bispecific monoclonal antibody that can focus effector T-cell activity. Proc Natl Acad Sci U S A (1986) 1.40
Generation of diversity of the beta chain of the human T-lymphocyte receptor for antigen. Proc Natl Acad Sci U S A (1986) 1.37
Increased frequency of T cell receptor V alpha 12.1 expression on CD8+ T cells: evidence that V alpha participates in shaping the peripheral T cell repertoire. J Exp Med (1991) 1.33
Double-negative (CD4-CD8-) lymphocytes bearing T-cell receptor alpha and beta chains in normal human skin. Proc Natl Acad Sci U S A (1989) 1.27
Diversity and structure of human T cell receptor delta chain genes in peripheral blood gamma/delta-bearing T lymphocytes. J Exp Med (1989) 1.22
Exon/intron organization of the genes coding for the delta chains of the human and murine T-cell receptor/T3 complex. Proc Natl Acad Sci U S A (1986) 1.18
Tissue-specific expression of cell-surface Qa-2 antigen from a transfected Q7b gene of C57BL/10 mice. J Exp Med (1987) 1.18
Rearrangement and expression of T-cell antigen receptor genes in human T-lymphocyte tumor lines and normal human T-cell clones: evidence for allelic exclusion of Ti beta gene expression and preferential use of a J beta 2 gene segment. Mol Cell Biol (1986) 1.14
Regulation of T-cell receptor gene expression in human T-cell development. Proc Natl Acad Sci U S A (1985) 1.14
Expression of T cell receptor genes in human B cells. J Exp Med (1986) 1.10
Molecular mechanisms used by tumors to escape immune recognition: immunogenetherapy and the cell biology of major histocompatibility complex class I. J Immunother Emphasis Tumor Immunol (1993) 1.06
Comparison of T cell receptor alpha, beta, and gamma gene rearrangement and expression in T cell acute lymphoblastic leukemia. J Clin Invest (1988) 1.04
A new HLA-linked T cell membrane molecule, related to the beta chain of the clonotypic receptor, is associated with T3. J Exp Med (1986) 1.00
Gamma gene rearrangement and expression in autoreactive helper T cells. J Exp Med (1986) 0.98
Two distinct T-cell receptor alpha-chain transcripts in a rabbit T-cell line: implications for allelic exclusion in T cells. Proc Natl Acad Sci U S A (1986) 0.98
Restriction fragment length polymorphism of the gene encoding the alpha chain of the human T cell receptor. J Exp Med (1985) 0.96
T cell receptor beta gene has two downstream DNase I hypersensitive regions. Possible mechanisms of tissue- and stage-specific gene regulation. J Exp Med (1989) 0.90
Association between a T cell receptor restriction fragment length polymorphism and systemic lupus erythematosus. J Clin Invest (1990) 0.89
Rearrangement and expression of the alpha- and beta-chain genes of the T-cell antigen receptor in functional murine suppressor T-cell clones. Proc Natl Acad Sci U S A (1985) 0.88
Recombinant interferon alpha can induce rearrangement of T-cell antigen receptor alpha-chain genes and maturation to cytotoxicity in T-lymphocyte clones in vitro. Proc Natl Acad Sci U S A (1986) 0.88
Maturation or differentiation of human thymocyte precursors in vitro? Proc Natl Acad Sci U S A (1990) 0.87
Use of a variable alpha region to create a functional T-cell receptor delta chain. Proc Natl Acad Sci U S A (1988) 0.87
T cell receptor delta gene rearrangements in acute lymphoblastic leukemia. J Clin Invest (1988) 0.86
Biology of the human histocompatibility leukocyte antigen (HLA) system and a hypothesis regarding the generation of autoimmune diseases. J Clin Invest (1986) 0.86
Gene correction in the evolution of the T cell receptor beta chain. J Exp Med (1986) 0.85
Rearrangement and expression of the antigen receptor alpha, beta and gamma genes in suppressor antigen-specific T cell lines. EMBO J (1985) 0.83
Genetic recombination within the human T-cell receptor alpha-chain gene complex. Proc Natl Acad Sci U S A (1987) 0.83
The T cell antigen receptor. Biochem J (1985) 0.80
Identification of tissue specific nuclear proteins: DNA sequence and protein binding regions in the T cell receptor beta J-C intron. Nucleic Acids Res (1990) 0.80
Identification of genes for the constant region of rabbit T-cell receptor beta chains. Proc Natl Acad Sci U S A (1985) 0.77
TRAC variants associate with IgA nephropathy. J Am Soc Nephrol (2009) 0.76
Complete cDNA sequence coding for the human T cell receptor alpha chain HPB-ALL. Nucleic Acids Res (1988) 0.75
Detection of T cell receptor alpha chain locus rearrangements in human antigen-specific T lymphocyte clones using a DNA probe specific for chromosome region 14q11. J Exp Med (1986) 0.75
Missing: a diagnostic technique to enumerate antigen-specific T cells. Crit Rev Oncol Hematol (2011) 0.75
The isolation of structural genes from libraries of eucaryotic DNA. Cell (1978) 37.13
Transformation of mammalian cells with genes from procaryotes and eucaryotes. Cell (1979) 21.15
T cell tolerance by clonal elimination in the thymus. Cell (1987) 13.83
Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition. J Exp Med (1981) 12.03
The staphylococcal enterotoxins and their relatives. Science (1990) 11.99
Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors. J Immunol (1989) 8.19
Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. Science (1990) 8.17
The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J Exp Med (1983) 7.55
Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci U S A (1989) 7.48
The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice. Cell (1989) 7.02
Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing. J Exp Med (1983) 6.97
Control of homeostasis of CD8+ memory T cells by opposing cytokines. Science (2000) 6.22
The autopsy as a measure of accuracy of the death certificate. N Engl J Med (1985) 5.78
Superantigens: mechanism of T-cell stimulation and role in immune responses. Annu Rev Immunol (1991) 5.71
V beta-specific stimulation of human T cells by staphylococcal toxins. Science (1989) 5.34
Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Nature (1999) 5.03
Stimulation of a major subset of lymphocytes expressing T cell receptor gamma delta by an antigen derived from Mycobacterium tuberculosis. Cell (1989) 4.53
The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens. Nature (1988) 4.43
Vitamin A supplementation and increased prevalence of childhood diarrhoea and acute respiratory infections. Lancet (1993) 4.35
The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J Exp Med (1984) 4.29
T cells compete for access to antigen-bearing antigen-presenting cells. J Exp Med (2000) 4.16
Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes. Immunity (1998) 4.15
Interleukin-induced increase in Ia expression by normal mouse B cells. J Exp Med (1984) 4.14
A T cell receptor V beta segment that imparts reactivity to a class II major histocompatibility complex product. Cell (1987) 4.09
The T cell receptor. Science (1987) 4.00
Report of the Conference on Low Blood Cholesterol: Mortality Associations. Circulation (1992) 3.98
Type I interferons keep activated T cells alive. J Exp Med (1999) 3.98
Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo. Cell Immunol (2001) 3.91
Streptococcal anti-desoxyribonuclease B: microtechnique determination. J Lab Clin Med (1968) 3.88
Superantigens and their potential role in human disease. Adv Immunol (1993) 3.88
Altering genotype and phenotype by DNA-mediated gene transfer. Science (1980) 3.82
Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen. J Immunol (1984) 3.72
Evidence for the effects of a superantigen in rheumatoid arthritis. Science (1991) 3.71
The role of the T cell receptor in positive and negative selection of developing T cells. Science (1990) 3.64
The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product. J Exp Med (1983) 3.54
A superantigen encoded in the open reading frame of the 3' long terminal repeat of mouse mammary tumour virus. Nature (1991) 3.47
Antigen presentation by Ia+ B cell hybridomas to H-2-restricted T cell hybridomas. Proc Natl Acad Sci U S A (1982) 3.41
B cell helper factors. I. Requirement for both interleukin 2 and another 40,000 mol wt factor. J Exp Med (1981) 3.40
Development of the nursing section of the community health team. Br Med J (1968) 3.40
The toxicity of staphylococcal enterotoxin B in mice is mediated by T cells. J Exp Med (1990) 3.31
The MHC molecule I-E is necessary but not sufficient for the clonal deletion of V beta 11-bearing T cells. J Exp Med (1989) 3.30
Superantigens interact with MHC class II molecules outside of the antigen groove. Cell (1990) 3.20
Experimental lepromatous leprosy. Nature (1967) 3.18
An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proc Natl Acad Sci U S A (1999) 3.15
Autoimmune disease: why and where it occurs. Nat Med (2001) 3.04
The repertoire of T cells shaped by a single MHC/peptide ligand. Cell (1996) 3.04
Concanavalin A-inducible, interleukin-2-producing T cell hybridoma. J Exp Med (1980) 3.02
Production of soluble MHC class II proteins with covalently bound single peptides. Nature (1994) 2.98
Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question. J Immunol (2001) 2.93
A maternally inherited superantigen encoded by a mammary tumour virus. Nature (1991) 2.92
Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen. Nature (1987) 2.89
Reactive oxygen species regulate activation-induced T cell apoptosis. Immunity (1999) 2.84
Antigen presentation by supported planar membranes containing affinity-purified I-Ad. Proc Natl Acad Sci U S A (1984) 2.80
Two better cell lines for making hybridomas expressing specific T cell receptors. J Immunol (1989) 2.78
Immunological adjuvants promote activated T cell survival via induction of Bcl-3. Nat Immunol (2001) 2.76
Isolation of transforming DNA: cloning the hamster aprt gene. Cell (1980) 2.73
Cytokine-induced survival of activated T cells in vitro and in vivo. Proc Natl Acad Sci U S A (1998) 2.71
Selective expansion of T cells expressing V beta 2 in toxic shock syndrome. J Exp Med (1990) 2.71
Molecular basis of different forms of metachromatic leukodystrophy. N Engl J Med (1991) 2.69
Phenotypic suppression of nonsense mutants in yeast by aminoglycoside antibiotics. Nature (1979) 2.66
The major histocompatibility complex-restricted antigen receptor on T cells: distribution on thymus and peripheral T cells. Cell (1984) 2.64
Transfusion-associated acquired immunodeficiency syndrome. Evidence for persistent infection in blood donors. N Engl J Med (1985) 2.62
Residues of the variable region of the T-cell-receptor beta-chain that interact with S. aureus toxin superantigens. Nature (1990) 2.60
The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas. Cell (1983) 2.58
Widespread divergence between incipient Anopheles gambiae species revealed by whole genome sequences. Science (2010) 2.58
Structures of an MHC class II molecule with covalently bound single peptides. Science (1996) 2.58
An endogenous retrovirus mediating deletion of alpha beta T cells? Nature (1991) 2.57
Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med (1983) 2.56
Mls--a retrovirus exploits the immune system. Immunol Today (1991) 2.54