Published in J Exp Med on February 01, 1978
Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors. J Exp Med (1984) 3.36
Ia antigen-bearing B cell tumor lines can present protein antigen and alloantigen in a major histocompatibility complex-restricted fashion to antigen-reactive T cells. J Exp Med (1982) 3.01
Mapping of antigenic and functional epitopes on the alpha- and beta-subunits of two related mouse glycoproteins involved in cell interactions, LFA-1 and Mac-1. J Exp Med (1983) 2.78
Cellular and genetic control of antibody responses. V. Helper T-cell recognition of H-2 determinants on accessory cells but not B cells. J Exp Med (1979) 2.75
Antigen presentation by resting B cells. Radiosensitivity of the antigen-presentation function and two distinct pathways of T cell activation. J Exp Med (1984) 2.71
Biochemical characterization of a second family of human Ia molecules, HLA-DS, equivalent to murine I-A subregion molecules. J Exp Med (1982) 2.15
The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression. J Exp Med (1978) 2.00
The specific direct interaction of helper T cells and antigen-presenting B cells. Proc Natl Acad Sci U S A (1986) 1.98
Purification of functional, determinant-specific, idiotype-bearing murine T cells. J Exp Med (1978) 1.70
Role of interleukin 1 in anti-immunoglobulin-induced B cell proliferation. J Exp Med (1983) 1.69
Major histocompatibility complex-restricted antigen presentation to antigen-reactive T cells by B lymphocyte tumor cells. J Exp Med (1981) 1.60
Effects of blocking helper T cell induction in vivo with anti-Ia antibodies. Possible role of I-A/E hybrid molecules as restriction elements. J Exp Med (1980) 1.59
Functional analysis of T cells expressing Ia antigens. I. Demonstration of helper T-cell heterogeneity. J Exp Med (1979) 1.53
TAP, a novel T cell-activating protein involved in the stimulation of MHC-restricted T lymphocytes. J Exp Med (1986) 1.49
The role of H-2-linked genes in helper T-cell function. VI. Expression of Ir genes by helper T cells. J Exp Med (1979) 1.33
The histocompatibility restrictions on macrophage T-helper cell interaction determine the histocompatibility restrictions on T-helper cell B-cell interaction. J Exp Med (1978) 1.32
Isotype specificity of helper T cell clones. Peyer's patch Th cells preferentially collaborate with mature IgA B cells for IgA responses. J Exp Med (1984) 1.31
Functional role of HLA class I cell-surface molecules in human T-lymphocyte activation and proliferation. Proc Natl Acad Sci U S A (1986) 1.19
Role of the major histocompatibility gene products in regulating the antibody response to dinitrophenylated poly(L-Glu55,L-Ala35,L-Phe9)n. J Exp Med (1980) 1.16
Genetic control of the immune response to collagen. II. Antibody responses produced in fetal liver restored radiation chimeras and thymus reconstituted F1 hybrid nude mice. J Exp Med (1979) 1.15
Analysis of histocompatibility requirements for proliferative and helper T cell activity. T cell populations depleted of alloreactive cells by negative selection. J Exp Med (1980) 1.14
Antigen presentation by a B-cell line transfected with cloned immunoglobulin heavy- and light-chain genes specific for a defined hapten. Proc Natl Acad Sci U S A (1986) 1.02
Phospholipase treatment of accessory cells that have been exposed to antigen selectively inhibits antigen-specific Ia-restricted, but not allospecific, stimulation of T lymphocytes. Proc Natl Acad Sci U S A (1986) 0.96
Functional helper activity of monoclonal T cell populations: antigen-specific and H-2 restricted cloned T cells provide help for in vitro antibody responses to trinitrophenyl-poly(LTyr,Glu)-poly(DLAla)--poly(LLys). Proc Natl Acad Sci U S A (1981) 0.96
Immune response genes controlling responsiveness to major transplantation antigens. Specific major histocompatibility complex-linked defect for antibody responses to class I alloantigens. J Exp Med (1982) 0.94
Suppressor T-cell activity in responder X nonresponder (C57BL/10 X DBA/1)F1 spleen cells responsive to L-glutamic acid60-L-alanine30-L-tyrosine10. J Exp Med (1978) 0.90
Two genetically identical antigen-presenting cell clones display heterogeneity in antigen processing. Proc Natl Acad Sci U S A (1989) 0.89
Macrophages: modulators of immunity. Parke-Davis Award Lecture. Am J Pathol (1980) 0.88
Bridging channel dendritic cells induce immunity to transfused red blood cells. J Exp Med (2016) 0.85
Clonal analysis of F1 hybrid helper T cells restricted to parental or F1 hybrid major histocompatibility determinants. J Exp Med (1980) 0.85
T-helper function of parent leads to F1 chimeras. Presence of a separate T-cell subgroup able to stimulate allogeneic B cells but not syngeneic B cells. J Exp Med (1979) 0.85
The role of accessory cells and T cell-growth factor in induction of cytotoxic T lymphocytes against herpes simplex virus antigens. Immunology (1981) 0.84
Eicosapentaenoic acid inhibits antigen-presenting cell function of murine splenocytes. Immunology (1992) 0.82
Positive selection of major histocompatibility complex-restricted suppressor T cells bearing the predominant idiotype in the immune response to lysozyme. Proc Natl Acad Sci U S A (1981) 0.78
Adaptive differentiation of murine lymphocytes. IV (Responder x nonresponder) F1 T cells can be taught to preferentially help nonresponder, rather than responder, B cells. J Exp Med (1979) 0.77
Lymphocytes. 1. Function. Genetic restrictions in the immune response. J Clin Pathol Suppl (R Coll Pathol) (1979) 0.76
Immunization of dissociated spleen cell cultures from normal mice. J Exp Med (1967) 30.93
Antitrinitrophenyl (TNP) plaque assay. Primary response of Balb/c mice to soluble and particulate immunogen. Proc Soc Exp Biol Med (1969) 18.89
Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytes. J Exp Med (1973) 11.59
Separation of mouse spleen cells by passage through columns of sephadex G-10. J Immunol Methods (1974) 7.19
Function of macrophages in antigen recognition by guinea pig T lymphocytes. II. Role of the macrophage in the regulation of genetic control of the immune response. J Exp Med (1973) 7.14
The role of macrophages in the generation of T-helper cells. II. The genetic control of the macrophage-T-cell interaction for helper cell induction with soluble antigens. J Exp Med (1975) 5.48
Antigen-specific T-cell factor in cell cooperation. Mapping within the I region of the H-2 complex and ability to cooperate across allogeneic barriers. J Exp Med (1975) 4.64
Functional specificity of thymus- dependent lymphocytes. Science (1977) 4.31
Cell interactions between histoincompatible T and B lymphocytes. The H-2 gene complex determines successful physiologic lymphocyte interactions. Proc Natl Acad Sci U S A (1973) 4.12
Role of major histocompatibility complex gene products in delayed-type hypersensitivity. Proc Natl Acad Sci U S A (1976) 3.69
An in vitro primary immune response to 2,4,6-trinitrophenyl substituted erythrocytes: response against carrier and hapten. J Immunol (1970) 3.63
Regulation by the H-2 gene complex of macrophage-lymphoid cell interactions in secondary antibody responses in vitro. J Exp Med (1976) 3.10
Determinant selection is a macrophage dependent immune response gene function. Nature (1977) 2.85
The modulation of lymphocyte functions by molecules secreted by macrophages. I. Description and partial biochemical analysis. J Exp Med (1975) 2.54
Macrophage-lymphocyte interaction. II. Antigen-mediated physical interactions between immune guinea pig lymph node lymphocytes and syngeneic macrophages. J Exp Med (1975) 2.44
Enhancement of antibody synthesis in vitro by mercaptoethanol. Cell Immunol (1972) 2.37
Helper T cells recognise antigen and macrophage surface components simultaneously. Nature (1976) 2.18
Regulatory mechanisms in cell-mediated immune responses. II. A genetically restricted suppressor of mixed lymphocyte reactions released by alloantigen-activated spleen cells. J Exp Med (1975) 2.18
Genetic control of the antibody response to poly-L(Tyr,Glu)-poly-D,L-Ala--poly-L-Lys in C3H--CWB tetraparental mice. J Exp Med (1974) 2.14
Macrophage-lymphocyte interaction. I. Characteristics of the antigen-independent-binding of guinea pig thymocytes and lymphocytes to syngeneic macrophages. J Exp Med (1973) 2.00
Cell components in the immune response. II. Cell attachment separation of immune cells. Cell Immunol (1970) 1.94
Independent populations of primed F1 guinea pig T lymphocytes respond to antigen-pulsed parental peritoneal exudate cells. J Exp Med (1977) 1.88
The lymphocyte surface. II. Separation of Fc receptor, C'3 receptor and surface immunoglobulin-bearing lymphocytes. Proc R Soc Lond B Biol Sci (1974) 1.76
The antigen specificity of thymus-derived helper cells. J Immunol (1972) 1.70
Antigen-specific and nonspecific mediators of T cell/B cell cooperation. III. Characterization of the nonspecific mediator(s) from different sources. J Immunol (1976) 1.69
Nature of the antigenic complex recognized by T lymphocytes. I. Analysis with an in vitro primary response to soluble protein antigens. J Exp Med (1976) 1.68
Regulation of the immune response. II. Qualitative and quantitative differences between thymus- and bone marrow-derived lymphocytes in the recognition of antigen. J Exp Med (1973) 1.57
The role of H-2-linked genes in helper T-cell function. I. In vitro expression in B cells of immune response genes controlling helper T-cell activity. J Exp Med (1977) 1.49
In vitro selection and extended culture of antigen-specific T lymphocytes. II. Mechanisms of selection. J Immunol (1975) 1.16
Genetic restriction of macrophage-lymphocyte interactions in secondary antibody responses in vitro. Cold Spring Harb Symp Quant Biol (1977) 1.09
In vitro selection and extended culture of antigen-specific T lymphocytes. I. Description of selection culture procedure and initial characterization of selected cells. J Exp Med (1975) 1.01
Polyclonal stimulation of lymphocytes by macrophages. Eur J Immunol (1976) 0.94
Nature of the antigenic complex recognized by T lymphocytes II. T-cell activation by direct modification of macrophage histocompatibility antigens. J Exp Med (1977) 0.88
T cell tolerance by clonal elimination in the thymus. Cell (1987) 13.83
Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition. J Exp Med (1981) 12.03
Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors. J Immunol (1989) 8.19
Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. Science (1990) 8.17
The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J Exp Med (1983) 7.55
Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci U S A (1989) 7.48
The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice. Cell (1989) 7.02
Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing. J Exp Med (1983) 6.97
Control of homeostasis of CD8+ memory T cells by opposing cytokines. Science (2000) 6.22
Superantigens: mechanism of T-cell stimulation and role in immune responses. Annu Rev Immunol (1991) 5.71
V beta-specific stimulation of human T cells by staphylococcal toxins. Science (1989) 5.34
The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens. Nature (1988) 4.43
The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J Exp Med (1984) 4.29
T cells compete for access to antigen-bearing antigen-presenting cells. J Exp Med (2000) 4.16
Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes. Immunity (1998) 4.15
Interleukin-induced increase in Ia expression by normal mouse B cells. J Exp Med (1984) 4.14
A T cell receptor V beta segment that imparts reactivity to a class II major histocompatibility complex product. Cell (1987) 4.09
Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo. Cell Immunol (2001) 3.91
Superantigens and their potential role in human disease. Adv Immunol (1993) 3.88
Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen. J Immunol (1984) 3.72
Evidence for the effects of a superantigen in rheumatoid arthritis. Science (1991) 3.71
The role of the T cell receptor in positive and negative selection of developing T cells. Science (1990) 3.64
The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product. J Exp Med (1983) 3.54
A superantigen encoded in the open reading frame of the 3' long terminal repeat of mouse mammary tumour virus. Nature (1991) 3.47
Antigen presentation by Ia+ B cell hybridomas to H-2-restricted T cell hybridomas. Proc Natl Acad Sci U S A (1982) 3.41
B cell helper factors. I. Requirement for both interleukin 2 and another 40,000 mol wt factor. J Exp Med (1981) 3.40
Superantigens interact with MHC class II molecules outside of the antigen groove. Cell (1990) 3.20
An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proc Natl Acad Sci U S A (1999) 3.15
The repertoire of T cells shaped by a single MHC/peptide ligand. Cell (1996) 3.04
Concanavalin A-inducible, interleukin-2-producing T cell hybridoma. J Exp Med (1980) 3.02
Production of soluble MHC class II proteins with covalently bound single peptides. Nature (1994) 2.98
Primary structure of human T-cell receptor alpha-chain. Nature (1985) 2.93
Antigen presentation by supported planar membranes containing affinity-purified I-Ad. Proc Natl Acad Sci U S A (1984) 2.80
Two better cell lines for making hybridomas expressing specific T cell receptors. J Immunol (1989) 2.78
Immunological adjuvants promote activated T cell survival via induction of Bcl-3. Nat Immunol (2001) 2.76
Cytokine-induced survival of activated T cells in vitro and in vivo. Proc Natl Acad Sci U S A (1998) 2.71
Selective expansion of T cells expressing V beta 2 in toxic shock syndrome. J Exp Med (1990) 2.71
The major histocompatibility complex-restricted antigen receptor on T cells: distribution on thymus and peripheral T cells. Cell (1984) 2.64
Residues of the variable region of the T-cell-receptor beta-chain that interact with S. aureus toxin superantigens. Nature (1990) 2.60
The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas. Cell (1983) 2.58
Structures of an MHC class II molecule with covalently bound single peptides. Science (1996) 2.58
Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med (1983) 2.56
Identification of the region of T cell receptor beta chain that interacts with the self-superantigen MIs-1a. Cell (1990) 2.42
Mutations defining functional regions of the superantigen staphylococcal enterotoxin B. J Exp Med (1992) 2.38
HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells. J Exp Med (1990) 2.30
Lipopolysaccharide interferes with the induction of peripheral T cell death. Immunity (1995) 2.29
Antigen-specific and nonspecific mediators of T cell/B cell cooperation. I. Evidence for their production by different T cells. J Immunol (1975) 2.26
Antigen-specific. I region-restricted interactions in vitro between tumor cell lines and T cell hybridomas. J Immunol (1982) 2.26
Superantigens: bacterial and viral proteins that manipulate the immune system. Annu Rev Cell Biol (1993) 2.26
Use of I region-restricted, antigen-specific T cell hybridomas to produce idiotypically specific anti-receptor antibodies. J Immunol (1983) 2.19
Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4. J Exp Med (1997) 2.15
Rearrangement of T-cell receptor beta-chain genes during T-cell development. Proc Natl Acad Sci U S A (1985) 2.13
The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma. J Exp Med (1984) 2.13
Gene transfer of H-2 class II genes: antigen presentation by mouse fibroblast and hamster B-cell lines. Cell (1984) 2.12
Compartmentalization of MHC class II gene expression in transgenic mice. Cell (1988) 2.08
CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection. J Exp Med (1999) 2.04
The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. Cell (1983) 2.04
The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity. J Exp Med (1983) 2.03
The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression. J Exp Med (1978) 2.00
Unexpected expansions of CD8-bearing cells in old mice. J Immunol (1993) 1.98
The T cell receptor: the alpha and beta chains define idiotype, and antigen and MHC specificity. Cell (1985) 1.96
Functional heterogeneity among the T-derived lymphocytes of the mouse. I. Analysis by adult thymectomy. J Immunol (1974) 1.91
The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR. Cell (1989) 1.91
IL-6 rescues resting mouse T cells from apoptosis. J Immunol (1997) 1.89
Role of gamma-interferon in antibody-producing responses. Nature (1984) 1.87
Two types of functionally distinct, synergizing helper T cells. J Immunol (1980) 1.85
Activation changes the spectrum but not the diversity of genes expressed by T cells. Proc Natl Acad Sci U S A (1999) 1.84
A role for clonal inactivation in T cell tolerance to Mls-1a. Nature (1990) 1.75
The antigen-specific, major histocompatibility complex-restricted receptor on T cells. Adv Immunol (1986) 1.73
Identification of the staphylococcal enterotoxin A superantigen binding site in the beta 1 domain of the human histocompatibility antigen HLA-DR. Proc Natl Acad Sci U S A (1991) 1.71
The antigen specificity of thymus-derived helper cells. J Immunol (1972) 1.70
Antigen-specific and nonspecific mediators of T cell/B cell cooperation. III. Characterization of the nonspecific mediator(s) from different sources. J Immunol (1976) 1.69