Published in Circulation on November 01, 1989
Brain natriuretic peptide as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide. J Clin Invest (1991) 3.70
Increased angiotensin-I converting enzyme gene expression in the failing human heart. Quantification by competitive RNA polymerase chain reaction. J Clin Invest (1994) 0.97
An approach to endomyocardial biopsy interpretation. J Clin Pathol (2006) 0.95
Ventricular expression of atrial and brain natriuretic peptides in dilated cardiomyopathy. An immunohistocytochemical study of the endomyocardial biopsy specimens using specific monoclonal antibodies. Am J Pathol (1993) 0.82
Effect of phorbol ester on the release of atrial natriuretic peptide from the hypertrophied rat myocardium. Br J Pharmacol (1991) 0.77
Atrophic cardiomyocyte signaling in hypertensive heart disease. J Cardiovasc Pharmacol (2013) 0.76
Contribution of the ventricles and the atrial appendages to the elevation of plasma atrial natriuretic factor (ANF) during pacing-induced heart failure in conscious dogs. Basic Res Cardiol (1997) 0.75
ANP expression in the hypertensive heart. Exp Clin Cardiol (2002) 0.75
Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction. Immunity (2000) 10.34
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol (2000) 9.85
Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors. Nature (2000) 7.15
The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. Immunity (1994) 6.18
A family of cAMP-binding proteins that directly activate Rap1. Science (1998) 6.12
Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. Proc Natl Acad Sci U S A (1996) 6.04
Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. Mol Cell (2000) 5.92
Convenient test for screening metallo-beta-lactamase-producing gram-negative bacteria by using thiol compounds. J Clin Microbiol (2000) 5.69
PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes (2001) 5.18
The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase. EMBO J (1996) 5.09
p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin. EMBO J (1997) 5.03
Spatio-temporal images of growth-factor-induced activation of Ras and Rap1. Nature (2001) 4.83
STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J (1999) 4.55
Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1. EMBO J (1994) 4.37
A missense mutation of the endothelin-B receptor gene in multigenic Hirschsprung's disease. Cell (1994) 4.35
Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages. Cell (1995) 4.34
p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions. FEBS Lett (1997) 4.31
Trends in healthy life expectancy in the United States, 1970-1990: gender, racial, and educational differences. Soc Sci Med (2001) 4.30
SCE-963, a new broad-spectrum cephalosporin: in vitro and in vivo antibacterial activities. Antimicrob Agents Chemother (1978) 4.06
A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system. Neuron (2000) 3.93
Brain natriuretic peptide as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide. J Clin Invest (1991) 3.70
Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice. Genes Cells (1999) 3.69
Localization and mechanism of secretion of B-type natriuretic peptide in comparison with those of A-type natriuretic peptide in normal subjects and patients with heart failure. Circulation (1994) 3.63
Circulating microRNAs in plasma of patients with gastric cancers. Br J Cancer (2010) 3.59
A new endoscopic mucosal resection procedure using an insulation-tipped electrosurgical knife for rectal flat lesions: report of two cases. Gastrointest Endosc (1999) 3.55
Routine coagulation of visible vessels may prevent delayed bleeding after endoscopic submucosal dissection--an analysis of risk factors. Endoscopy (2008) 3.50
The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas. Cancer (1999) 3.47
ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice. FEBS Lett (1996) 3.46
T-786-->C mutation in the 5'-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm. Circulation (1999) 3.41
Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas. Nat Genet (1998) 3.38
Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans. Nat Med (1997) 3.35
Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans. J Clin Endocrinol Metab (2001) 3.16
Cefmenoxime (SCE-1365), a novel broad-spectrum cephalosporin: in vitro and in vivo antibacterial activities. Antimicrob Agents Chemother (1981) 3.03
Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho. Science (1996) 2.99
Specificity of DNase I. Estimation of nucleosides present at the 5'-phosphate terminus of a limit digest of DNA by DNase I. J Biochem (1966) 2.96
Neutrophil gelatinase-associated lipocalin as the real-time indicator of active kidney damage. Kidney Int (2007) 2.93
ACE inhibitors and symptomless dysphagia. Lancet (1998) 2.92
Phospholipase C assay using p-nitrophenylphosphoryl-choline together with sorbitol and its application to studying the metal and detergent requirement of the enzyme. Anal Biochem (1976) 2.87
Activation of Rac1 by a Crk SH3-binding protein, DOCK180. Genes Dev (1998) 2.82
Type II collagen-induced murine arthritis. I. Induction and perpetuation of arthritis require synergy between humoral and cell-mediated immunity. J Immunol (1988) 2.80
Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study. Diabetologia (2003) 2.80
Significance of myocytes with positive DNA in situ nick end-labeling (TUNEL) in hearts with dilated cardiomyopathy: not apoptosis but DNA repair. Circulation (1999) 2.80
Beta-lactamase stability and antibacterial activity of cefmenoxime (SCE-1365), a novel cephalosporin. Antimicrob Agents Chemother (1981) 2.72
Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor. Genes Cells (1997) 2.72
Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders. Proc Natl Acad Sci U S A (1996) 2.70
Human immunodeficiency virus vpr gene encodes a virion-associated protein. AIDS Res Hum Retroviruses (1990) 2.67
Rac1 is required for the formation of three germ layers during gastrulation. Oncogene (1998) 2.61
Open reading frame vpr of simian immunodeficiency virus encodes a virion-associated protein. J Virol (1990) 2.60
Cardiac fibrosis in mice lacking brain natriuretic peptide. Proc Natl Acad Sci U S A (2000) 2.58
K-ras is essential for the development of the mouse embryo. Oncogene (1997) 2.57
Evolutionary pattern of the hemagglutinin gene of influenza B viruses isolated in Japan: cocirculating lineages in the same epidemic season. J Virol (1990) 2.54
Expression of the Fas ligand in cells of T cell lineage. J Immunol (1995) 2.54
Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice. J Clin Invest (1999) 2.50
Association studies of 33 single nucleotide polymorphisms (SNPs) in 29 candidate genes for bronchial asthma: positive association a T924C polymorphism in the thromboxane A2 receptor gene. Hum Genet (2000) 2.50
A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia. Proc Natl Acad Sci U S A (1998) 2.47
DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane. Mol Cell Biol (1996) 2.44
"Apoptotic" myocytes in infarct area in rabbit hearts may be oncotic myocytes with DNA fragmentation: analysis by immunogold electron microscopy combined with In situ nick end-labeling. Circulation (1998) 2.43
Ghrelin strongly stimulates growth hormone release in humans. J Clin Endocrinol Metab (2000) 2.43
Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development. Development (2001) 2.42
Considerable time from the onset of plaque rupture and/or thrombi until the onset of acute myocardial infarction in humans: coronary angiographic findings within 1 week before the onset of infarction. Circulation (2000) 2.42
Takayasu's arteritis. Clinical report of eighty-four cases and immunological studies of seven cases. Circulation (1967) 2.42
Preoperative identification of meningiomas that are highly likely to recur. J Neurosurg (1999) 2.38
Immunological properties of Rickettsia tsutsugamushi, Kawasaki strain, isolated from a patient in Kyushu. Microbiol Immunol (1986) 2.38
Superiority of brain natriuretic peptide as a hormonal marker of ventricular systolic and diastolic dysfunction and ventricular hypertrophy. Hypertension (1996) 2.37
Production of human alpha-interferon in silkworm using a baculovirus vector. Nature (1985) 2.37
Tumor necrosis factor-alpha (TNF-alpha) plays a protective role in acute viralmyocarditis in mice: A study using mice lacking TNF-alpha. Circulation (2001) 2.36
Helicobacter pylori CagA interacts with E-cadherin and deregulates the beta-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells. Oncogene (2007) 2.34
Vectors carrying two separate T-DNAs for co-transformation of higher plants mediated by Agrobacterium tumefaciens and segregation of transformants free from selection markers. Plant J (1996) 2.32
T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6. J Exp Med (1994) 2.31
Chromoscopy during colonoscopy. Endoscopy (2001) 2.30
Further evidence on recent trends in the prevalence and incidence of disability among older Americans from two sources: the LSOA and the NHIS. J Gerontol B Psychol Sci Soc Sci (1997) 2.28
Molecular cloning and functional characterization of the receptor for Clostridium perfringens enterotoxin. J Cell Biol (1997) 2.25
Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i) Nature (1999) 2.23
Overexpression of connective tissue growth factor in podocytes worsens diabetic nephropathy in mice. Kidney Int (2007) 2.21
Human immunodeficiency virus type 1 has an additional coding sequence in the central region of the genome. Proc Natl Acad Sci U S A (1988) 2.20
Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an "emergency" cardiac hormone against ventricular overload. J Clin Invest (1995) 2.15
Endoscopic indications for endoscopic mucosal resection of laterally spreading tumours in the colorectum. Gut (2006) 2.14
Pathology of the heart in Kawasaki disease. Pediatrics (1978) 2.10
mGluR1 in cerebellar Purkinje cells essential for long-term depression, synapse elimination, and motor coordination. Science (2000) 2.09
The addition of phenylephrine contributes to the development of transient neurologic symptoms after spinal anesthesia with 0.5% tetracaine. Anesthesiology (1997) 2.06
Nitric oxide activity is deficient in spasm arteries of patients with coronary spastic angina. Circulation (1996) 2.06
Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide. Endocrinology (1992) 2.06
Direct stimulation of monocyte release of interleukin 1 by mycobacterial protein antigens. J Immunol (1986) 2.05
The long-term effects of polymethylmethacrylate contact lens wear on the corneal endothelium. Ophthalmology (1994) 2.05
Different secretion patterns of atrial natriuretic peptide and brain natriuretic peptide in patients with congestive heart failure. Circulation (1993) 2.04
Serotype-specific amplification of Rickettsia tsutsugamushi DNA by nested polymerase chain reaction. J Clin Microbiol (1993) 2.03
The relationships of proteinuria, serum creatinine, glomerular filtration rate with cardiovascular disease mortality in Japanese general population. Kidney Int (2006) 2.02