Published in Genome Biol on July 31, 2014
Global SUMOylation on active chromatin is an acute heat stress response restricting transcription. Genome Biol (2015) 0.84
SUMO, a small, but powerful, regulator of double-strand break repair. Philos Trans R Soc Lond B Biol Sci (2017) 0.78
Mapping the SUMOylated landscape. FEBS J (2015) 0.77
Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo. J Biol Chem (2016) 0.76
In Vitro Studies Reveal a Sequential Mode of Chain Processing by the Yeast SUMO (Small Ubiquitin-related Modifier)-specific Protease Ulp2. J Biol Chem (2015) 0.76
Flightless-I governs cell fate by recruiting the SUMO isopeptidase SENP3 to distinct HOX genes. Epigenetics Chromatin (2017) 0.75
Redox regulation of SUMO enzymes is required for ATM activity and survival in oxidative stress. EMBO J (2016) 0.75
SUMO-specific protease 3 is a key regulator for hepatic lipid metabolism in non-alcoholic fatty liver disease. Sci Rep (2016) 0.75
DeSUMOylation of Gli1 by SENP1 Attenuates Sonic Hedgehog Signaling. Mol Cell Biol (2017) 0.75
Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast. Mol Cell (2000) 6.39
A new protease required for cell-cycle progression in yeast. Nature (1999) 5.44
The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition. Nat Rev Mol Cell Biol (2010) 4.72
Ubiquitin-like proteins: new wines in new bottles. Gene (2000) 3.46
The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein. Mol Cell Biol (2000) 3.24
Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex. Mol Cell Biol (2002) 2.85
Sumoylation: a regulatory protein modification in health and disease. Annu Rev Biochem (2013) 2.66
Function and regulation of SUMO proteases. Nat Rev Mol Cell Biol (2012) 2.55
SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development. Mol Cell (2010) 2.52
Association of the human SUMO-1 protease SENP2 with the nuclear pore. J Biol Chem (2002) 2.33
Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3. J Biol Chem (2006) 2.15
A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex. Structure (2004) 2.15
The SUMO protease SENP5 is required to maintain mitochondrial morphology and function. J Cell Sci (2007) 2.12
Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates. Nat Struct Mol Biol (2006) 2.07
SUMO protease SENP1 induces isomerization of the scissile peptide bond. Nat Struct Mol Biol (2006) 1.89
A novel mammalian Smt3-specific isopeptidase 1 (SMT3IP1) localized in the nucleolus at interphase. Eur J Biochem (2000) 1.75
NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins. J Biol Chem (2003) 1.64
Identification and characterization of DEN1, a deneddylase of the ULP family. J Biol Chem (2003) 1.62
Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs. J Biol Chem (2007) 1.61
Mutation of SENP1/SuPr-2 reveals an essential role for desumoylation in mouse development. Mol Cell Biol (2005) 1.52
Characterization of SENP7, a SUMO-2/3-specific isopeptidase. Biochem J (2009) 1.51
Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex. Mol Cell (2010) 1.50
The structure of SENP1-SUMO-2 complex suggests a structural basis for discrimination between SUMO paralogues during processing. Biochem J (2006) 1.49
The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing. EMBO Rep (2008) 1.47
SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia. EMBO J (2013) 1.47
Structure of the human SENP7 catalytic domain and poly-SUMO deconjugation activities for SENP6 and SENP7. J Biol Chem (2008) 1.47
SUMO Losing Balance: SUMO Proteases Disrupt SUMO Homeostasis to Facilitate Cancer Development and Progression. Genes Cancer (2010) 1.42
SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation. EMBO J (2009) 1.41
Translocation of SenP5 from the nucleoli to the mitochondria modulates DRP1-dependent fission during mitosis. J Biol Chem (2009) 1.37
Distribution and paralogue specificity of mammalian deSUMOylating enzymes. Biochem J (2010) 1.33
Nucleocytoplasmic shuttling modulates activity and ubiquitination-dependent turnover of SUMO-specific protease 2. Mol Cell Biol (2006) 1.29
SENP1 induces prostatic intraepithelial neoplasia through multiple mechanisms. J Biol Chem (2010) 1.29
Control of nuclear activities by substrate-selective and protein-group SUMOylation. Annu Rev Genet (2013) 1.25
The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex. EMBO J (2011) 1.24
The SUMO protease SENP6 is essential for inner kinetochore assembly. J Cell Biol (2010) 1.21
RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin. Mol Biol Cell (2008) 1.19
Activity profiling of human deSUMOylating enzymes (SENPs) with synthetic substrates suggests an unexpected specificity of two newly characterized members of the family. Biochem J (2008) 1.18
Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. J Cell Biol (2008) 1.18
DeSUMOylating isopeptidase: a second class of SUMO protease. EMBO Rep (2012) 1.18
SUMO-specific protease 1 promotes prostate cancer progression and metastasis. Oncogene (2012) 1.16
Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions. EMBO Rep (2012) 1.15
Arf-induced turnover of the nucleolar nucleophosmin-associated SUMO-2/3 protease Senp3. Cell Cycle (2008) 1.13
SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation. Mol Cell (2012) 1.11
Redox regulation of the stability of the SUMO protease SENP3 via interactions with CHIP and Hsp90. EMBO J (2010) 1.11
The dynamics and mechanism of SUMO chain deconjugation by SUMO-specific proteases. J Biol Chem (2011) 1.06
Differential expression of SUMO-specific protease 7 variants regulates epithelial-mesenchymal transition. Proc Natl Acad Sci U S A (2012) 1.05
LAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesis. Mol Biol Cell (2011) 1.03
Yeast Ulp1, an Smt3-specific protease, associates with nucleoporins. J Biochem (2000) 1.02
Conjugation of Smt3 to dorsal may potentiate the Drosophila immune response. Mol Cell Biol (2002) 0.98
SENP1 and SENP2 affect spatial and temporal control of sumoylation in mitosis. Mol Biol Cell (2013) 0.93
Senp1 is essential for desumoylating Sumo1-modified proteins but dispensable for Sumo2 and Sumo3 deconjugation in the mouse embryo. Cell Rep (2013) 0.93
The SUMO-specific isopeptidase SENP2 associates dynamically with nuclear pore complexes through interactions with karyopherins and the Nup107-160 nucleoporin subcomplex. Mol Biol Cell (2011) 0.93
Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6. PLoS Pathog (2013) 0.92
The SUMO protease SENP6 is a direct regulator of PML nuclear bodies. Mol Biol Cell (2010) 0.91
The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair. EMBO Rep (2013) 0.91
The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activation. J Immunol (2012) 0.90
The SUMO system: a master organizer of nuclear protein assemblies. Chromosoma (2013) 0.88
SUMO routes ribosome maturation. Nucleus (2011) 0.87
Coordinated regulation of transcription factor Bcl11b activity in thymocytes by the mitogen-activated protein kinase (MAPK) pathways and protein sumoylation. J Biol Chem (2012) 0.87
The fate of metaphase kinetochores is weighed in the balance of SUMOylation during S phase. Cell Cycle (2010) 0.84
The biphasic redox sensing of SENP3 accounts for the HIF-1 transcriptional activity shift by oxidative stress. Acta Pharmacol Sin (2012) 0.83
A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II. J Cell Sci (2014) 0.82
The SUMO protease Verloren regulates dendrite and axon targeting in olfactory projection neurons. J Neurosci (2012) 0.82
The SUMO-specific isopeptidase SENP3 regulates MLL1/MLL2 methyltransferase complexes and controls osteogenic differentiation. Mol Cell (2014) 0.81
Crystal structure of DeSI-1, a novel deSUMOylase belonging to a putative isopeptidase superfamily. Proteins (2012) 0.81
Overexpression of SENP3 in oral squamous cell carcinoma and its association with differentiation. Oncol Rep (2013) 0.79
Inhibition of SENP1 induces radiosensitization in lung cancer cells. Exp Ther Med (2013) 0.78
Down-regulation of SENP1 expression increases apoptosis of Burkitt lymphoma cells. Asian Pac J Cancer Prev (2012) 0.78
Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes. PLoS Biol (2005) 4.33
Chromosome territories--a functional nuclear landscape. Curr Opin Cell Biol (2006) 3.82
Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity. Proc Natl Acad Sci U S A (2002) 2.85
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53. Proc Natl Acad Sci U S A (2003) 2.73
Radioembolization with yttrium-90 glass microspheres in hepatocellular carcinoma: European experience on safety and long-term survival. Hepatology (2010) 2.60
The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase. EMBO J (2002) 2.56
Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates. Proc Natl Acad Sci U S A (2002) 2.53
Plastin 3 is a protective modifier of autosomal recessive spinal muscular atrophy. Science (2008) 2.51
Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome. Diabetes (2011) 2.29
Strumpellin is a novel valosin-containing protein binding partner linking hereditary spastic paraplegia to protein aggregation diseases. Brain (2010) 1.93
Cellular targets of gefitinib. Cancer Res (2005) 1.87
The Arabidopsis elch mutant reveals functions of an ESCRT component in cytokinesis. Development (2006) 1.74
The SBML ODE Solver Library: a native API for symbolic and fast numerical analysis of reaction networks. Bioinformatics (2006) 1.61
Characterization of peptides released from mitochondria: evidence for constant proteolysis and peptide efflux. J Biol Chem (2004) 1.53
Multicolor 3D fluorescence in situ hybridization for imaging interphase chromosomes. Methods Mol Biol (2008) 1.52
Subinhibitory concentrations of linezolid reduce Staphylococcus aureus virulence factor expression. Antimicrob Agents Chemother (2004) 1.43
Implantation of artificial penile nodules--a review of literature. J Sex Med (2010) 1.41
Are molecular cytogenetics and bioinformatics suggesting diverging models of ancestral mammalian genomes? Genome Res (2006) 1.38
Structural characterization of TSC-36/Flik: analysis of two charge isoforms. J Biol Chem (2003) 1.33
Synergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5. Nat Cell Biol (2006) 1.31
Chemical proteomic analysis reveals alternative modes of action for pyrido[2,3-d]pyrimidine kinase inhibitors. Mol Cell Proteomics (2004) 1.28
Flow-structure-acoustic interaction in a human voice model. J Acoust Soc Am (2009) 1.27
Acquisition protocol considerations for combined PET/CT imaging. J Nucl Med (2004) 1.27
Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways. Proc Natl Acad Sci U S A (2002) 1.27
Induction of Bim and Bid gene expression during accelerated apoptosis in severe sepsis. Crit Care (2008) 1.21
Proteomic characterization of the angiogenesis inhibitor SU6668 reveals multiple impacts on cellular kinase signaling. Cancer Res (2005) 1.21
Viral oncoproteins E1A and E7 and cellular LxCxE proteins repress SUMO modification of the retinoblastoma tumor suppressor. Oncogene (2005) 1.21
Molecular characterization of the pericentric inversion that causes differences between chimpanzee chromosome 19 and human chromosome 17. Am J Hum Genet (2002) 1.19
Segmental duplications and evolutionary plasticity at tumor chromosome break-prone regions. Genome Res (2008) 1.16
Sumoylation of poly(ADP-ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function. FASEB J (2009) 1.15
Evolutionarily conserved, cell type and species-specific higher order chromatin arrangements in interphase nuclei of primates. Chromosoma (2007) 1.13
Nuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in {beta}-cells. J Cell Biol (2004) 1.12
Substrates related to chromatin and to RNA-dependent processes are modified by Arabidopsis SUMO isoforms that differ in a conserved residue with influence on desumoylation. Plant Physiol (2009) 1.10
Breakpoint analysis of the pericentric inversion distinguishing human chromosome 4 from the homologous chromosome in the chimpanzee (Pan troglodytes). Hum Mutat (2005) 1.10
Identification and validation of novel adipokines released from primary human adipocytes. Mol Cell Proteomics (2011) 1.10
Chromosome reshuffling in birds of prey: the karyotype of the world's largest eagle (Harpy eagle, Harpia harpyja) compared to that of the chicken (Gallus gallus). Chromosoma (2005) 1.09
A serial lectin approach to the mucin-type O-glycoproteome of Drosophila melanogaster S2 cells. Proteomics (2007) 1.09
Role of the novel metallopeptidase Mop112 and saccharolysin for the complete degradation of proteins residing in different subcompartments of mitochondria. J Biol Chem (2005) 1.08
Allogeneic dendritic cells fused with tumor cells: preclinical results and outcome of a clinical phase I/II trial in patients with metastatic renal cell carcinoma. Hum Gene Ther (2003) 1.04
A canonical stability-elasticity relationship verified for one million face-centred-cubic structures. Nature (2012) 1.03
Steady state migratory RelB+ langerin+ dermal dendritic cells mediate peripheral induction of antigen-specific CD4+ CD25+ Foxp3+ regulatory T cells. Eur J Immunol (2011) 1.03
Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics (2012) 1.00
Chromosomal phylogeny of four Akodontini species (Rodentia, Cricetidae) from southern Brazil established by Zoo-FISH using Mus musculus (Muridae) painting probes. Chromosome Res (2008) 1.00
Identification of large-scale human-specific copy number differences by inter-species array comparative genomic hybridization. Hum Genet (2006) 0.99
Replication-timing-correlated spatial chromatin arrangements in cancer and in primate interphase nuclei. J Cell Sci (2008) 0.99
In vivo Polycomb kinetics and mitotic chromatin binding distinguish stem cells from differentiated cells. Genes Dev (2012) 0.97
Chromosomal instability, tolerance of mitotic errors and multidrug resistance are promoted by tetraploidization in human cells. Cell Cycle (2015) 0.96
Positron emission tomography guided therapy of aggressive non-Hodgkin lymphomas--the PETAL trial. Leuk Lymphoma (2009) 0.96
The phylogeny of howler monkeys (Alouatta, Platyrrhini): reconstruction by multicolor cross-species chromosome painting. Chromosome Res (2002) 0.96
[Subjective perception of radioactivity - no change post successful treatment with radioiodine]. Nuklearmedizin (2009) 0.94
Human intestinal TFF3 forms disulfide-linked heteromers with the mucus-associated FCGBP protein and is released by hydrogen sulfide. J Proteome Res (2010) 0.93
Structural variability of BM-40/SPARC/osteonectin glycosylation: implications for collagen affinity. Glycobiology (2004) 0.93
Fast adaptive coevolution of nuclear and mitochondrial subunits of ATP synthetase in orangutan. Mol Biol Evol (2004) 0.93
Metalloproteases meprin α and meprin β are C- and N-procollagen proteinases important for collagen assembly and tensile strength. Proc Natl Acad Sci U S A (2013) 0.92
Differential expression proteomics of human colorectal cancer based on a syngeneic cellular model for the progression of adenoma to carcinoma. Proteomics (2010) 0.92
Comparison of FDG-PET/CT and bone scintigraphy for detection of bone metastases in breast cancer. Acta Radiol (2011) 0.92
Physical properties of organic particulate UV absorbers used in sunscreens II. UV-attenuating efficiency as function of particle size. J Colloid Interface Sci (2004) 0.91
Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells. Proteomics (2011) 0.91
Therapeutic vaccination against metastatic renal cell carcinoma by autologous dendritic cells: preclinical results and outcome of a first clinical phase I/II trial. Cancer Immunol Immunother (2002) 0.91
Sesquiterpene lactones as inhibitors of IL-8 expression in HeLa cells. Bioorg Med Chem (2005) 0.90
Standardized qualitative evaluation of scar tissue properties in an animal wound healing model. Wound Repair Regen (2003) 0.89
Coupling of order parameters, chirality, and interfacial structures in multiferroic materials. J Phys Condens Matter (2011) 0.89
RICK activates a NF-kappaB-dependent anti-human cytomegalovirus response. J Biol Chem (2003) 0.89
Chemical de-O-glycosylation of glycoproteins for application in LC-based proteomics. Proteomics (2009) 0.88
The SUMO system: a master organizer of nuclear protein assemblies. Chromosoma (2013) 0.88
Microsclerodermins from terrestrial myxobacteria: an intriguing biosynthesis likely connected to a sponge symbiont. J Am Chem Soc (2013) 0.87
Transmembrane and secreted MUC1 probes show trafficking-dependent changes in O-glycan core profiles. Glycobiology (2005) 0.87
Enhanced activity of meprin-α, a pro-migratory and pro-angiogenic protease, in colorectal cancer. PLoS One (2011) 0.87
Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli. PLoS One (2011) 0.86
Evolutionary genomic remodelling of the human 4q subtelomere (4q35.2). BMC Evol Biol (2007) 0.86
Casein kinase 2 phosphorylation of protein kinase C and casein kinase 2 substrate in neurons (PACSIN) 1 protein regulates neuronal spine formation. J Biol Chem (2013) 0.86
Cell Preparation and Multicolor FISH in 3D Preserved Cultured Mammalian Cells. CSH Protoc (2007) 0.85
Proteomic characterization of aggregate components in an intrafamilial variable FHL1-associated myopathy. Neuromuscul Disord (2013) 0.85
Selective internal radiation therapy of hepatocellular carcinoma: potential hepatopulmonary shunt reduction after sorafenib administration. J Vasc Interv Radiol (2012) 0.84
Ten-year trends in intoxications and requests for emergency ambulance service. Prehosp Emerg Care (2012) 0.83
O-glucosylation and O-fucosylation occur together in close proximity on the first epidermal growth factor repeat of AMACO (VWA2 protein). J Biol Chem (2008) 0.83
Parameter identification for chemical reaction systems using sparsity enforcing regularization: a case study for the chlorite-iodide reaction. J Phys Chem A (2009) 0.83
Proteolytic processing causes extensive heterogeneity of tissue matrilin forms. J Biol Chem (2009) 0.82
Blimp-1Deltaexon7: a naturally occurring Blimp-1 deletion mutant with auto-regulatory potential. Exp Cell Res (2008) 0.82
Therapy Operating Characteristic (TOC) Curves and their Application to the Evaluation of Segmentation Algorithms. Proc SPIE Int Soc Opt Eng (2010) 0.81
Interaction of the developmental regulator SALL1 with UBE2I and SUMO-1. Biochem Biophys Res Commun (2002) 0.81
Selective internal radiotherapy (SIRT) of hepatic tumors: how to deal with the cystic artery. Cardiovasc Intervent Radiol (2012) 0.81
Incidence and predictors of ventricular arrhythmias after ST-segment elevation myocardial infarction. Am J Emerg Med (2011) 0.81
Management of humeral head fractures with a trauma shoulder prosthesis: correlation between joint function and healing of the tuberosities. Acta Orthop Belg (2007) 0.81
Risk factors for prolonged intensive care treatment following atrial septal defect closure in adults. Int J Cardiol (2007) 0.81
Porcine gastric TFF2 is a mucus constituent and differs from pancreatic TFF2. Cell Physiol Biochem (2014) 0.80
Analysis of methylated O-glycan alditols by reversed-phase NanoLC coupled CAD-ESI mass spectrometry. Methods Mol Biol (2009) 0.80
Patient-specific protein aggregates in myofibrillar myopathies: laser microdissection and differential proteomics for identification of plaque components. Proteomics (2012) 0.80
Purification of the CaaX-modified, dynamin-related large GTPase hGBP1 by coexpression with farnesyltransferase. J Lipid Res (2010) 0.80
Pitfalls of interim positron emission tomography scanning in diffuse large B-cell lymphoma. J Clin Oncol (2010) 0.80
Shared and unique properties of ubiquitin and SUMO interaction networks in DNA repair. Genes Dev (2011) 0.80
Variant alleles of the mannose binding lectin 2 gene (MBL2) confer heterozygote advantage within Crohn's families. Scand J Gastroenterol (2010) 0.80
Association of deficiency for mannan-binding lectin with anti-mannan antibodies in Crohn's disease: a family study. Inflamm Bowel Dis (2007) 0.79
Comparison of locking and nonlocking plates in the treatment of mandibular condyle fractures. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 0.79
High-resolution chromosome painting reveals the first genetic signature for the chiropteran suborder Pteropodiformes (Mammalia: Chiroptera). Chromosome Res (2011) 0.79
Anti-Saccharomyces cerevisiae mannan antibodies (ASCA) of Crohn's patients crossreact with mannan from other yeast strains, and murine ASCA IgM can be experimentally induced with Candida albicans. Inflamm Bowel Dis (2007) 0.79
Regulatory Functions of Ubiquitin and SUMO in DNA Repair Pathways. Subcell Biochem (2010) 0.79
Identification of a gene in Leishmania infantum encoding a protein that contains a SP-RING/MIZ zinc finger domain. Biochim Biophys Acta (2003) 0.78
A minimal and self-consistent in silico cell model based on macromolecular interactions. Philos Trans R Soc Lond B Biol Sci (2007) 0.78
Characterization of recombinant and natural forms of the human LIM domain-containing protein FHL2. Protein Expr Purif (2003) 0.78