Published in PLoS Genet on October 16, 2014
Aurora B prevents chromosome arm separation defects by promoting telomere dispersion and disjunction. J Cell Biol (2015) 0.84
The proper connection between shelterin components is required for telomeric heterochromatin assembly. Genes Dev (2016) 0.78
Ccq1-Tpz1TPP1 interaction facilitates telomerase and SHREC association with telomeres in fission yeast. Mol Biol Cell (2015) 0.76
Minishelterins separate telomere length regulation and end protection in fission yeast. Genes Dev (2015) 0.76
Sequential and counter-selectable cassettes for fission yeast. BMC Biotechnol (2016) 0.75
TeloPCR-seq: a high-throughput sequencing approach for telomeres. FEBS Lett (2016) 0.75
Spatial organization and molecular interactions of the Schizosaccharomyces pombe Ccq1-Tpz1-Poz1 shelterin complex. J Mol Biol (2017) 0.75
Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe. Yeast (1998) 18.47
Telomerase catalytic subunit homologs from fission yeast and human. Science (1997) 12.35
How shelterin protects mammalian telomeres. Annu Rev Genet (2008) 11.20
The RNA component of human telomerase. Science (1995) 9.86
Pot1, the putative telomere end-binding protein in fission yeast and humans. Science (2001) 6.95
An alternative pathway for yeast telomere maintenance rescues est1- senescence. Cell (1993) 6.89
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. Nature (2007) 6.82
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT. Nat Genet (1997) 6.69
Comparative functional genomics of the fission yeasts. Science (2011) 6.00
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication. Cell (2009) 5.74
Regulation of telomerase by telomeric proteins. Annu Rev Biochem (2004) 5.69
Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature (1997) 4.49
TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase. Nature (2007) 4.23
The telomere syndromes. Nat Rev Genet (2012) 4.01
Replication and protection of telomeres. Nature (2007) 3.98
Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae. Mol Cell Biol (1999) 3.79
The telomerase reverse transcriptase: components and regulation. Genes Dev (1998) 3.63
The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres. Cell (2006) 3.45
PTOP interacts with POT1 and regulates its localization to telomeres. Nat Cell Biol (2004) 3.33
How telomeres are replicated. Nat Rev Mol Cell Biol (2007) 3.27
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex. Genes Dev (2004) 3.25
Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity. Proc Natl Acad Sci U S A (1997) 3.11
Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length. Science (2008) 2.97
SHREC, an effector complex for heterochromatic transcriptional silencing. Cell (2007) 2.90
Functional human telomeres are recognized as DNA damage in G2 of the cell cycle. Mol Cell (2005) 2.89
Removal of shelterin reveals the telomere end-protection problem. Science (2012) 2.87
Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe. Nature (1998) 2.84
Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells. Cell (2009) 2.76
TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends. Cell (2012) 2.74
spRap1 and spRif1, recruited to telomeres by Taz1, are essential for telomere function in fission yeast. Curr Biol (2001) 2.64
Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis. EMBO J (2007) 2.61
Semi-conservative DNA replication through telomeres requires Taz1. Nature (2006) 2.53
A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2. Curr Biol (2004) 2.45
TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo. Mol Cell Biol (2010) 2.39
TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres. J Biol Chem (2004) 2.36
The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature (2012) 2.33
TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice. Dev Cell (2010) 2.24
In vivo stoichiometry of shelterin components. J Biol Chem (2009) 2.12
A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly. Proc Natl Acad Sci U S A (2006) 2.04
Telomere binding protein Taz1 establishes Swi6 heterochromatin independently of RNAi at telomeres. Curr Biol (2005) 2.02
TER1, the RNA subunit of fission yeast telomerase. Nat Struct Mol Biol (2007) 1.92
Identification and characterization of the Schizosaccharomyces pombe TER1 telomerase RNA. Nat Struct Mol Biol (2007) 1.90
Telomere binding of the Rap1 protein is required for meiosis in fission yeast. Curr Biol (2001) 1.89
Accelerated telomere shortening in ataxia telangiectasia. Nat Genet (1996) 1.82
Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres. Genetics (2002) 1.78
Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST. Cell (2012) 1.77
Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast. Proc Natl Acad Sci U S A (2001) 1.73
Telomere protection by TPP1/POT1 requires tethering to TIN2. Mol Cell (2011) 1.62
Differential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres. EMBO J (2009) 1.54
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres. PLoS Genet (2008) 1.52
Fission yeast Ccq1 is telomerase recruiter and local checkpoint controller. Genes Dev (2008) 1.47
Telomeres and disease. EMBO J (2009) 1.41
Tel1ATM and Rad3ATR kinases promote Ccq1-Est1 interaction to maintain telomeres in fission yeast. Nat Struct Mol Biol (2011) 1.31
Telomere maintenance in fission yeast requires an Est1 ortholog. Curr Biol (2003) 1.30
Human CST has independent functions during telomere duplex replication and C-strand fill-in. Cell Rep (2012) 1.29
Fission yeast Tel1(ATM) and Rad3(ATR) promote telomere protection and telomerase recruitment. PLoS Genet (2009) 1.20
ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase. J Cell Biol (2010) 1.17
Tel1(ATM) and Rad3(ATR) phosphorylate the telomere protein Ccq1 to recruit telomerase and elongate telomeres in fission yeast. Genes Dev (2012) 1.15
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes. J Cell Biol (2008) 1.14
Extra-chromosomal telomeric DNA in cells from Atm(-/-) mice and patients with ataxia-telangiectasia. Hum Mol Genet (2001) 1.11
Protection and replication of telomeres in fission yeast. Biochem Cell Biol (2009) 1.10
Recombination-based telomere maintenance is dependent on Tel1-MRN and Rap1 and inhibited by telomerase, Taz1, and Ku in fission yeast. Mol Cell Biol (2007) 1.04
Fission yeast shelterin regulates DNA polymerases and Rad3(ATR) kinase to limit telomere extension. PLoS Genet (2013) 0.99
Tpz1 controls a telomerase-nonextendible telomeric state and coordinates switching to an extendible state via Ccq1. Genes Dev (2013) 0.99
HAATI survivors replace canonical telomeres with blocks of generic heterochromatin. Nature (2010) 0.98
Pot1 inactivation leads to rampant telomere resection and loss in one cell cycle. Nucleic Acids Res (2010) 0.93
Roles of heterochromatin and telomere proteins in regulation of fission yeast telomere recombination and telomerase recruitment. J Biol Chem (2009) 0.92
Identification of the functional domains of the telomere protein Rap1 in Schizosaccharomyces pombe. PLoS One (2012) 0.90
Telomere regulation during the cell cycle in fission yeast. Methods Mol Biol (2014) 0.79
Fission yeast shelterin regulates DNA polymerases and Rad3(ATR) kinase to limit telomere extension. PLoS Genet (2013) 0.99
Swi1Timeless Prevents Repeat Instability at Fission Yeast Telomeres. PLoS Genet (2016) 0.79