DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration.

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Published in Proc Natl Acad Sci U S A on October 27, 2014

Authors

Younghee Kim1, Valeria Tarallo2, Nagaraj Kerur1, Tetsuhiro Yasuma1, Bradley D Gelfand3, Ana Bastos-Carvalho1, Yoshio Hirano1, Reo Yasuma1, Takeshi Mizutani1, Benjamin J Fowler4, Shengjian Li1, Hiroki Kaneko1, Sasha Bogdanovich1, Balamurali K Ambati5, David R Hinton6, William W Hauswirth7, Razqallah Hakem8, Charles Wright1, Jayakrishna Ambati9

Author Affiliations

1: Department of Ophthalmology and Visual Sciences.
2: Department of Ophthalmology and Visual Sciences, Angiogenesis Lab, Institute of Genetics and Biophysics, Consiglio Nazionale delle Ricerche, 80131 Naples, Italy;
3: Department of Ophthalmology and Visual Sciences, Department of Biomedical Engineering, Department of Microbiology, Immunology, and Human Genetics, and.
4: Department of Ophthalmology and Visual Sciences, Department of Physiology, University of Kentucky, Lexington, KY 40536;
5: Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah School of Medicine, Salt Lake City, UT 84132; Department of Ophthalmology, Veterans Affairs Salt Lake City Healthcare System, Salt Lake City, UT 84148;
6: Departments of Pathology and Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033;
7: Department of Ophthalmology, University of Florida, Gainesville, FL 32610; and.
8: Ontario Cancer Institute, University Health Network, and Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada M5G 2M9.
9: Department of Ophthalmology and Visual Sciences, Department of Physiology, University of Kentucky, Lexington, KY 40536; jamba2@email.uky.edu.

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