Published in Science on January 02, 2015
Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans. JAMA (2015) 5.30
Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer. Cell (2015) 3.54
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals. Endocr Rev (2015) 2.51
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. Nature (2016) 2.50
Substantial contribution of extrinsic risk factors to cancer development. Nature (2015) 2.46
Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: treating cancer like an infectious disease. Oncotarget (2015) 2.28
Preventable Incidence and Mortality of Carcinoma Associated With Lifestyle Factors Among White Adults in the United States. JAMA Oncol (2016) 2.22
Is bad luck the main cause of cancer? J Natl Cancer Inst (2015) 2.02
Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer. Cell (2015) 1.89
A Critical Examination of the "Bad Luck" Explanation of Cancer Risk. Cancer Prev Res (Phila) (2015) 1.68
Frequent Somatic Mutation in Adult Intestinal Stem Cells Drives Neoplasia and Genetic Mosaicism during Aging. Cell Stem Cell (2015) 1.42
Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis. Nature (2017) 1.39
Cancer risk: role of chance overstated. Science (2015) 1.36
The most important questions in cancer research and clinical oncology-Question 2-5. Obesity-related cancers: more questions than answers. Chin J Cancer (2017) 1.33
Biomedicine. The bad luck of cancer. Science (2015) 1.32
Multi-organ Mapping of Cancer Risk. Cell (2016) 1.30
Cancer risk: prevention is crucial. Science (2015) 1.29
Tissue-specific mutation accumulation in human adult stem cells during life. Nature (2016) 1.24
Immunity, inflammation, and cancer: an eternal fight between good and evil. J Clin Invest (2015) 1.24
Revised Estimates for the Number of Human and Bacteria Cells in the Body. PLoS Biol (2016) 1.24
Evolutionary determinants of cancer. Cancer Discov (2015) 1.19
Cancer risk: role of environment. Science (2015) 1.19
Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance. Blood (2015) 1.16
Cancer risk: tumors excluded. Science (2015) 1.14
Cancer risk: accuracy of literature. Science (2015) 1.13
Cancer risk: many factors contribute. Science (2015) 1.13
Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer. Cell Stem Cell (2015) 1.11
The H19 Long non-coding RNA in cancer initiation, progression and metastasis - a proposed unifying theory. Mol Cancer (2015) 1.08
An integrative view on sex differences in brain tumors. Cell Mol Life Sci (2015) 1.04
Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study. JAMA Oncol (2017) 1.00
The mathematics of cancer: integrating quantitative models. Nat Rev Cancer (2015) 1.00
Cancer risk: role of environment—response. Science (2015) 0.99
Cancer: Risk factors and random chances. Nature (2015) 0.99
Pancreatic cancer biology and genetics from an evolutionary perspective. Nat Rev Cancer (2016) 0.98
Role of stem-cell divisions in cancer risk. Nature (2017) 0.97
Deoxyribonucleotide metabolism, mutagenesis and cancer. Nat Rev Cancer (2015) 0.96
Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment. J Clin Invest (2015) 0.95
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. Carcinogenesis (2015) 0.95
Mutation and Human Exceptionalism: Our Future Genetic Load. Genetics (2016) 0.95
Peto's paradox and the promise of comparative oncology. Philos Trans R Soc Lond B Biol Sci (2015) 0.94
E-cadherin can limit the transforming properties of activating β-catenin mutations. EMBO J (2015) 0.94
A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells. Nat Commun (2016) 0.93
Interpreting the Dependence of Mutation Rates on Age and Time. PLoS Biol (2016) 0.93
Towards cancer-aware life-history modelling. Philos Trans R Soc Lond B Biol Sci (2015) 0.93
Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution. PLoS Genet (2016) 0.92
Strategies to Prevent "Bad Luck" in Cancer. J Natl Cancer Inst (2015) 0.92
Directed Differentiation of Human Embryonic Stem Cells into Prostate Organoids In Vitro and its Perturbation by Low-Dose Bisphenol A Exposure. PLoS One (2015) 0.91
LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans. Genes Dev (2015) 0.91
Development and validation of risk prediction algorithms to estimate future risk of common cancers in men and women: prospective cohort study. BMJ Open (2015) 0.91
Stem Cells as Hormone Targets That Lead to Increased Cancer Susceptibility. Endocrinology (2015) 0.89
Mutated Fanconi anemia pathway in non-Fanconi anemia cancers. Oncotarget (2015) 0.88
Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells. Cell Rep (2015) 0.88
Age-related somatic mutations in the cancer genome. Oncotarget (2015) 0.87
The causality between smoking and lung cancer among groups and individuals: addressing issues in tobacco litigation in South Korea. Epidemiol Health (2015) 0.87
The multiple facets of Peto's paradox: a life-history model for the evolution of cancer suppression. Philos Trans R Soc Lond B Biol Sci (2015) 0.87
Control of Caenorhabditis elegans germ-line stem-cell cycling speed meets requirements of design to minimize mutation accumulation. BMC Biol (2015) 0.86
Peto's paradox and human cancers. Philos Trans R Soc Lond B Biol Sci (2015) 0.86
The migration ability of stem cells can explain the existence of cancer of unknown primary site. Rethinking metastasis. Oncoscience (2015) 0.86
Cancer prevention as part of precision medicine: 'plenty to be done'. Carcinogenesis (2015) 0.86
A Heritable Missense Polymorphism in CDKN2A Confers Strong Risk of Childhood Acute Lymphoblastic Leukemia and Is Preferentially Selected during Clonal Evolution. Cancer Res (2015) 0.86
The EGFR-HER2 module: a stem cell approach to understanding a prime target and driver of solid tumors. Oncogene (2015) 0.85
DNA replication stress: from molecular mechanisms to human disease. Chromosoma (2016) 0.84
Rs488087 single nucleotide polymorphism as predictive risk factor for pancreatic cancers. Oncotarget (2015) 0.84
Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3 null mice. Nat Cell Biol (2015) 0.84
Gut bacteria and cancer. Biochim Biophys Acta (2015) 0.84
Should tissue structure suppress or amplify selection to minimize cancer risk? Biol Direct (2016) 0.84
Somatic mosaicism: on the road to cancer. Nat Rev Cancer (2015) 0.83
Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells. Genes Nutr (2015) 0.83
Why does obesity promote cancer? Epidemiology, biology, and open questions. Ecancermedicalscience (2015) 0.83
High-throughput data integration of RNA-miRNA-circRNA reveals novel insights into mechanisms of benzo[a]pyrene-induced carcinogenicity. Nucleic Acids Res (2015) 0.83
Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage. Stem Cell Reports (2015) 0.82
How does HTLV-1 cause adult T-cell leukaemia/lymphoma (ATL)? Curr Opin Virol (2015) 0.82
Are Most Cancers Caused by Specific Risk Factors Acting on Tissues With High Underlying Stem Cell Divisions? J Natl Cancer Inst (2015) 0.82
Peto's paradox and the hallmarks of cancer: constructing an evolutionary framework for understanding the incidence of cancer. Philos Trans R Soc Lond B Biol Sci (2015) 0.82
Regulation of MYC gene expression by aberrant Wnt/β-catenin signaling in colorectal cancer. World J Biol Chem (2015) 0.82
Correlation of an epigenetic mitotic clock with cancer risk. Genome Biol (2016) 0.82
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Cancer Prevention: Obstacles, Challenges and the Road Ahead. J Natl Cancer Inst (2015) 0.82
Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing. Proc Natl Acad Sci U S A (2016) 0.81
Cell Fusion in the War on Cancer: A Perspective on the Inception of Malignancy. Int J Mol Sci (2016) 0.81
Cancer Microenvironment: What Can We Learn from the Stem Cell Niche. Int J Mol Sci (2015) 0.81
The Proliferative Activity of Mammary Epithelial Cells in Normal Tissue Predicts Breast Cancer Risk in Premenopausal Women. Cancer Res (2016) 0.81
Squamous Cell Cancers: A Unified Perspective on Biology and Genetics. Cancer Cell (2016) 0.81
The Fanconi anemia pathway is required for efficient repair of stress-induced DNA damage in haematopoietic stem cells. Cell Cycle (2015) 0.81
Update on Lynch syndrome genomics. Fam Cancer (2016) 0.81
Genetic Factors Are Not the Major Causes of Chronic Diseases. PLoS One (2016) 0.81
CRISPR/Cas9 and cancer targets: future possibilities and present challenges. Oncotarget (2016) 0.81
Cancer as a mitochondrial metabolic disease. Front Cell Dev Biol (2015) 0.81
A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics. Dis Model Mech (2015) 0.81
Targeting prion protein interactions in cancer. Prion (2015) 0.81
The role of dose rate in radiation cancer risk: evaluating the effect of dose rate at the molecular, cellular and tissue levels using key events in critical pathways following exposure to low LET radiation. Int J Radiat Biol (2016) 0.80
When stem cells grow old: phenotypes and mechanisms of stem cell aging. Development (2016) 0.80
Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers. Carcinogenesis (2016) 0.80
Fractionation of a tumor-initiating UV dose introduces DNA damage-retaining cells in hairless mouse skin and renders subsequent TPA-promoted tumors non-regressing. Oncotarget (2016) 0.80
Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma. Nat Commun (2015) 0.80
Preventing clonal evolutionary processes in cancer: Insights from mathematical models. Proc Natl Acad Sci U S A (2015) 0.80
Reduced Ovarian Cancer Incidence in Women Exposed to Low Dose Ionizing Background Radiation or Radiation to the Ovaries after Treatment for Breast Cancer or Rectosigmoid Cancer. Asian Pac J Cancer Prev (2016) 0.80
Using Nonlinear Stochastic Evolutionary Game Strategy to Model an Evolutionary Biological Network of Organ Carcinogenesis Under a Natural Selection Scheme. Evol Bioinform Online (2015) 0.80
On the apparent rarity of epithelial cancers in captive chimpanzees. Philos Trans R Soc Lond B Biol Sci (2015) 0.80
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