Published in Pain on April 01, 2015
Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice. Haematologica (2015) 0.93
Spinal glial activation and oxidative stress are alleviated by treatment with curcumin or coenzyme Q in sickle mice. Haematologica (2015) 0.87
Cannabinoid receptor-specific mechanisms to alleviate pain in sickle cell anemia via inhibition of mast cell activation and neurogenic inflammation. Haematologica (2015) 0.86
Frequency of Hospitalizations for Pain and Association With Altered Brain Network Connectivity in Sickle Cell Disease. J Pain (2015) 0.80
Comparative Analysis of Pain Behaviours in Humanized Mouse Models of Sickle Cell Anemia. PLoS One (2016) 0.79
An Evaluation of Central Sensitization in Patients With Sickle Cell Disease. J Pain (2016) 0.78
New insights into sickle cell disease: mechanisms and investigational therapies. Curr Opin Hematol (2016) 0.77
Endogenous BDNF augments NMDA receptor phosphorylation in the spinal cord via PLCγ, PKC, and PI3K/Akt pathways during colitis. J Neuroinflammation (2015) 0.77
Characterization of functional brain activity and connectivity using EEG and fMRI in patients with sickle cell disease. Neuroimage Clin (2016) 0.76
Updated Mechanisms of Sickle Cell Disease-Associated Chronic pain. Transl Perioper Pain Med (2015) 0.76
Cognitive and behavior deficits in sickle cell mice are associated with profound neuropathologic changes in hippocampus and cerebellum. Neurobiol Dis (2015) 0.75
CaMKIIα underlies spontaneous and evoked pain behaviors in Berkeley sickle cell transgenic mice. Pain (2016) 0.75
Chronic Opioid Therapy and Central Sensitization in Sickle Cell Disease. Am J Prev Med (2016) 0.75
Sickle cell disease: a natural model of acute and chronic pain. Pain (2017) 0.75
Electroacupuncture in conscious free-moving mice reduces pain by ameliorating peripheral and central nociceptive mechanisms. Sci Rep (2016) 0.75
Sensitization of C-fiber nociceptors in mice with sickle cell disease is decreased by local inhibition of anandamide hydrolysis. Pain (2017) 0.75
Mortality in sickle cell disease. Life expectancy and risk factors for early death. N Engl J Med (1994) 15.82
Neuronal plasticity: increasing the gain in pain. Science (2000) 8.85
Function and regulation of CREB family transcription factors in the nervous system. Neuron (2002) 7.99
Central sensitization: a generator of pain hypersensitivity by central neural plasticity. J Pain (2009) 7.11
Central sensitization: implications for the diagnosis and treatment of pain. Pain (2010) 6.88
Transgenic knockout mice with exclusively human sickle hemoglobin and sickle cell disease. Science (1997) 4.25
MAP kinase and pain. Brain Res Rev (2008) 3.75
The endothelial biology of sickle cell disease: inflammation and a chronic vasculopathy. Microcirculation (2004) 2.88
p38 MAPK, microglial signaling, and neuropathic pain. Mol Pain (2007) 2.72
Neuronal plasticity and signal transduction in nociceptive neurons: implications for the initiation and maintenance of pathological pain. Neurobiol Dis (2001) 2.49
Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids. Blood (2010) 2.45
Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing. J Neurochem (2003) 2.42
Pathology of Berkeley sickle cell mice: similarities and differences with human sickle cell disease. Blood (2005) 2.37
Sensory innervation of the viscera: peripheral basis of visceral pain. Physiol Rev (1994) 2.13
Mast cell activation contributes to sickle cell pathobiology and pain in mice. Blood (2013) 1.94
The kv4.2 potassium channel subunit is required for pain plasticity. Neuron (2006) 1.85
Dynamic receptive field plasticity in rat spinal cord dorsal horn following C-primary afferent input. Nature (1987) 1.82
MAPK activation in nociceptive neurons and pain hypersensitivity. Life Sci (2004) 1.81
Pathological pain and the neuroimmune interface. Nat Rev Immunol (2014) 1.73
Sickle cell pain: a critical reappraisal. Blood (2012) 1.69
Emerging role of Toll-like receptors in the control of pain and itch. Neurosci Bull (2012) 1.60
ERK integrates PKA and PKC signaling in superficial dorsal horn neurons. II. Modulation of neuronal excitability. J Neurophysiol (2003) 1.49
Fast synaptic inhibition in spinal sensory processing and pain control. Physiol Rev (2012) 1.45
Intracellular signaling in primary sensory neurons and persistent pain. Neurochem Res (2008) 1.44
The pharmacology of excitatory and inhibitory amino acid-mediated events in the transmission and modulation of pain in the spinal cord. Gen Pharmacol (1997) 1.44
Transient receptor potential vanilloid 1 mediates pain in mice with severe sickle cell disease. Blood (2011) 1.42
Patients with sickle cell disease have increased sensitivity to cold and heat. Am J Hematol (2012) 1.38
Inhibition of p38 mitogen-activated protein kinase attenuates interleukin-1beta-induced thermal hyperalgesia and inducible nitric oxide synthase expression in the spinal cord. J Neurochem (2005) 1.34
JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats. Brain (2011) 1.34
Windup leads to characteristics of central sensitization. Pain (1999) 1.29
The ERK/MAPK pathway, as a target for the treatment of neuropathic pain. Expert Opin Ther Targets (2005) 1.20
ERK integrates PKA and PKC signaling in superficial dorsal horn neurons. I. Modulation of A-type K+ currents. J Neurophysiol (2003) 1.20
Brain-derived neurotrophic factor induces NMDA receptor subunit one phosphorylation via ERK and PKC in the rat spinal cord. Eur J Neurosci (2004) 1.10
Climate and painful crisis of sickle-cell disease in Jamaica. Br Med J (1976) 1.10
Mouse models for studying pain in sickle disease: effects of strain, age, and acuteness. Br J Haematol (2011) 1.09
Windy weather and low humidity are associated with an increased number of hospital admissions for acute pain and sickle cell disease in an urban environment with a maritime temperate climate. Br J Haematol (2005) 1.05
Association between wind speed and the occurrence of sickle cell acute painful episodes: results of a case-crossover study. Br J Haematol (2008) 1.00
Cold hypersensitivity increases with age in mice with sickle cell disease. Pain (2014) 0.98
Letter: Sickling pain and season. Br Med J (1974) 0.96
Sensitization of cat dorsal horn neurons to innocuous mechanical stimulation after intradermal injection of capsaicin. Brain Res (1989) 0.95
Sickle cell mice exhibit mechanical allodynia and enhanced responsiveness in light touch cutaneous mechanoreceptors. Mol Pain (2012) 0.94
Sickle cell disease, vasculopathy, and therapeutics. Annu Rev Med (2012) 0.93
Tumor-evoked hyperalgesia and sensitization of nociceptive dorsal horn neurons in a murine model of cancer pain. Brain Res (2007) 0.93
Pre- and postsynaptic inhibitory control in the spinal cord dorsal horn. Ann N Y Acad Sci (2013) 0.92
Comparison of the immediate effects of surgical incision on dorsal horn neuronal receptive field size and responses during postnatal development. Anesthesiology (2008) 0.92
Relationship between meteorological changes and occurrence of painful sickle cell crises in Kuwait. Trans R Soc Trop Med Hyg (1980) 0.90
Thinking beyond sickling to better understand pain in sickle cell disease. Eur J Haematol (2014) 0.88
Biochemical and pharmacological assessment of MAP-kinase signaling along pain pathways in experimental rodent models: a potential tool for the discovery of novel antinociceptive therapeutics. Biochem Pharmacol (2013) 0.86
Spinal presynaptic inhibition in pain control. Neuroscience (2014) 0.84
Activation of C fibers by metabolic perturbations associated with tourniquet ischemia. Anesthesiology (1992) 0.83
Spike generation from dorsal roots and cutaneous afferents by hypoxia or hypercapnia in the rat in vivo. Exp Physiol (1999) 0.80
Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes. Blood (2003) 3.04
The itch-producing agents histamine and cowhage activate separate populations of primate spinothalamic tract neurons. J Neurosci (2007) 2.63
Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids. Blood (2010) 2.45
Mast cell activation contributes to sickle cell pathobiology and pain in mice. Blood (2013) 1.94
Sickle cell pain: a critical reappraisal. Blood (2012) 1.69
Variation in quantitative sensory testing and epidermal nerve fiber density in repeated measurements. Pain (2010) 1.58
Relief of itch by scratching: state-dependent inhibition of primate spinothalamic tract neurons. Nat Neurosci (2009) 1.51
Hematopoietic colony-stimulating factors mediate tumor-nerve interactions and bone cancer pain. Nat Med (2009) 1.45
Spinal neurons that possess the substance P receptor are required for the development of central sensitization. J Neurosci (2002) 1.42
A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain. Pain (2003) 1.25
Pruriceptive spinothalamic tract neurons: physiological properties and projection targets in the primate. J Neurophysiol (2012) 1.18
Opioids heal ischemic wounds in the rat. Wound Repair Regen (2005) 1.17
The analgesic potential of cannabinoids. J Opioid Manag (2010) 1.16
A decrease in anandamide signaling contributes to the maintenance of cutaneous mechanical hyperalgesia in a model of bone cancer pain. J Neurosci (2008) 1.13
Morphine stimulates vascular endothelial growth factor-like signaling in mouse retinal endothelial cells. Curr Neurovasc Res (2006) 1.10
Mouse models for studying pain in sickle disease: effects of strain, age, and acuteness. Br J Haematol (2011) 1.09
Morphine-induced epidermal growth factor pathway activation in non-small cell lung cancer. Anesth Analg (2011) 1.09
Chemical interactions between fibrosarcoma cancer cells and sensory neurons contribute to cancer pain. J Neurosci (2007) 1.06
Acute and chronic administration of the cannabinoid receptor agonist CP 55,940 attenuates tumor-evoked hyperalgesia. Eur J Pharmacol (2006) 1.06
Mechanism of cancer pain. Mol Interv (2010) 1.00
CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET). J Biol Chem (2011) 1.00
Re-organization of P2X3 receptor localization on epidermal nerve fibers in a murine model of cancer pain. Brain Res (2005) 1.00
Morphine induces mesangial cell proliferation and glomerulopathy via kappa-opioid receptors. Am J Physiol Renal Physiol (2008) 0.98
Influence of morphine on pericyte-endothelial interaction: implications for antiangiogenic therapy. J Oncol (2012) 0.98
NK-1 receptors modulate the excitability of ON cells in the rostral ventromedial medulla. J Neurophysiol (2006) 0.98
Cannabinoid modulation of cutaneous Adelta nociceptors during inflammation. J Neurophysiol (2008) 0.98
Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain. Pharmacol Res (2011) 0.97
Activation of peripheral cannabinoid receptors attenuates cutaneous hyperalgesia produced by a heat injury. Pain (2004) 0.96
Cannabinoid type-1 receptor reduces pain and neurotoxicity produced by chemotherapy. J Neurosci (2012) 0.96
NF-kappaB transcription factor p50 critically regulates tissue factor in deep vein thrombosis. J Biol Chem (2008) 0.95
Naloxone acts as an antagonist of estrogen receptor activity in MCF-7 cells. Mol Cancer Ther (2006) 0.95
Opioid requirement, opioid receptor expression, and clinical outcomes in patients with advanced prostate cancer. Cancer (2013) 0.94
Tumor-evoked hyperalgesia and sensitization of nociceptive dorsal horn neurons in a murine model of cancer pain. Brain Res (2007) 0.93
The cannabinoid receptor agonist, WIN 55, 212-2, attenuates tumor-evoked hyperalgesia through peripheral mechanisms. Brain Res (2008) 0.92
Endothelial nitric oxide synthase is dynamically expressed during bone marrow stem cell differentiation into endothelial cells. Am J Physiol Heart Circ Physiol (2007) 0.92
Tumor-evoked sensitization of C nociceptors: a role for endothelin. J Neurophysiol (2008) 0.90
NK-1 receptors in the rostral ventromedial medulla contribute to hyperalgesia produced by intraplantar injection of capsaicin. Pain (2008) 0.88
Opioids induce renal abnormalities in tumor-bearing mice. Nephron Exp Nephrol (2007) 0.88
Excitation of cutaneous C nociceptors by intraplantar administration of anandamide. Brain Res (2009) 0.87
Characterization of cutaneous primary afferent fibers excited by acetic acid in a model of nociception in frogs. J Neurophysiol (2003) 0.86
Spinal neurons that express NK-1 receptors modulate descending controls that project through the dorsolateral funiculus. J Neurophysiol (2004) 0.85
Subclinical peripheral neuropathy is a common finding in colorectal cancer patients prior to chemotherapy. Clin Cancer Res (2012) 0.85
Morphine induces albuminuria by compromising podocyte integrity. PLoS One (2013) 0.84
Termination zones of functionally characterized spinothalamic tract neurons within the primate posterior thalamus. J Neurophysiol (2008) 0.83
Differential modulation of neurons in the rostral ventromedial medulla by neurokinin-1 receptors. J Neurophysiol (2011) 0.82
CB1 and CB2 receptor agonists promote analgesia through synergy in a murine model of tumor pain. Behav Pharmacol (2011) 0.82
Morphine promotes renal pathology in sickle mice. Int J Nephrol Renovasc Dis (2012) 0.80
Cannabinoid agonist, CP 55,940, prevents capsaicin-induced sensitization of spinal cord dorsal horn neurons. J Neurophysiol (2004) 0.80
Blood outgrowth endothelial cells increase tumor growth rates and modify tumor physiology: relevance for therapeutic targeting. Cancers (Basel) (2013) 0.77
SYM 2081, an agonist that desensitizes kainate receptors, attenuates capsaicin and inflammatory hyperalgesia. Brain Res (2003) 0.77
Tumor angiogenesis 2012. J Oncol (2012) 0.76
Mactinin, a fragment of cytoskeletal alpha-actinin, is a novel inducer of heat shock protein (Hsp)-90 mediated monocyte activation. BMC Cell Biol (2009) 0.76
Carbon-fiber microelectrode amperometry reveals sickle-cell-induced inflammation and chronic morphine effects on single mast cells. ACS Chem Biol (2012) 0.76
Tumor angiogenesis. J Oncol (2010) 0.76
Could Perioperative Opioid Use Increase the Risk of Cancer Progression and Metastases? Int Anesthesiol Clin (2016) 0.75
Antitumor activity of a PPARdelta antagonist. Cancer Biol Ther (2009) 0.75
Sickle cell disease and bartonella spp. Infection. Mediterr J Hematol Infect Dis (2012) 0.75
Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. Cell Chem Biol (2017) 0.75
Self-Assembled 3D Nano-Split Rings for Plasmon-Enhanced Optofluidic Sensing. Nano Lett (2020) 0.75
A role for nk-1 neurons in the rostral ventromedial medulla in the development of chronic post-thoracotomy pain. Pain (2017) 0.75
A role for neurokinin-1 receptor neurons in the rostral ventromedial medulla in the development of chronic postthoracotomy pain. Pain (2017) 0.75
Sensitization of C-fiber nociceptors in mice with sickle cell disease is decreased by local inhibition of anandamide hydrolysis. Pain (2017) 0.75