PubRank

G Riou

Author PubWeight™ 78.66‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proc Natl Acad Sci U S A 1992 3.27
2 Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors. Proc Natl Acad Sci U S A 1995 2.56
3 Characterization of a human ovarian adenocarcinoma line, IGROV1, in tissue culture and in nude mice. Cancer Res 1985 2.06
4 Complete nucleotide sequence of minicircle kinetoplast DNA from Trypanosoma equiperdum. Proc Natl Acad Sci U S A 1981 1.56
5 Electron microscopy of the circular kinetoplastic DNA from Trypanosoma cruzi: occurrence of catenated forms. Proc Natl Acad Sci U S A 1969 1.49
6 Structure and expression of c-erbB-2 and EGF receptor genes in inflammatory and non-inflammatory breast cancer: prognostic significance. Int J Cancer 1989 1.35
7 Preparation and properties of nuclear and satellite deoxyribonucleic acid of Trypanosoma cruzi. J Mol Biol 1967 1.31
8 Replicating, convalently closed, circular DNA from kinetoplasts of Trypanosoma cruzi. Proc Natl Acad Sci U S A 1972 1.23
9 High incidence of p53 alterations (mutation, deletion, overexpression) in head and neck primary tumors and metastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal epithelium and in early non-invasive lesions. Oncogene 1995 1.18
10 ATP-independent type II topoisomerase from trypanosomes. Proc Natl Acad Sci U S A 1986 1.16
11 Overexpression of either c-myc or c-erbB-2/neu proto-oncogenes in human breast carcinomas: correlation with poor prognosis. Oncogene Res 1988 1.16
12 Strong association between c-myb and oestrogen-receptor expression in human breast cancer. Oncogene 1990 1.16
13 Purification and characterization of Plasmodium berghei DNA topoisomerases I and II: drug action, inhibition of decatenation and relaxation, and stimulation of DNA cleavage. Biochemistry 1986 1.11
14 Correlation of MDR1 gene expression with chemotherapy in neuroblastoma. J Natl Cancer Inst 1989 1.08
15 C-myc proto-oncogene expression and prognosis in early carcinoma of the uterine cervix. Lancet 1987 1.08
16 Expression of a human multidrug resistance gene in ovarian carcinomas. Cancer Res 1989 1.06
17 Absence of kinetoplast DNA in a late antigenic variant of Trypanosoma equiperdum. Mol Biochem Parasitol 1980 1.06
18 High incidence of loss of heterozygosity and abnormal imprinting of H19 and IGF2 genes in invasive cervical carcinomas. Uncoupling of H19 and IGF2 expression and biallelic hypomethylation of H19. Oncogene 1996 1.04
19 Abnormal circular DNA molecules induced by ethidium bromide in the kinetoplast of Trypanosoma cruzi. Proc Natl Acad Sci U S A 1969 1.02
20 [Fractionation and characterization of desoxyribonucleic acid (DNA) of trypanosomes (Trypanosoma equiperdum)]. C R Acad Sci Hebd Seances Acad Sci D 1966 1.00
21 Occurrence of a kinetoplast DNA-protein complex in Trypanosoma cruzi. Biochem Biophys Res Commun 1981 0.97
22 Loss of heterozygosity, allele silencing and decreased expression of p73 gene in breast cancers: prevalence of alterations in inflammatory breast cancers. Oncogene 2000 0.96
23 [Induction of a "dyskinetoplast" by ethidium bromide in Trypanosoma cruzi cultivated in vitro]. C R Acad Sci Hebd Seances Acad Sci D 1967 0.94
24 Combined analysis of DNA ploidy index and N-myc genomic content in neuroblastoma. Cancer Res 1991 0.93
25 Coactivation of the MDR1 and MYCN genes in human neuroblastoma cells during the metastatic process in the nude mouse. Cancer Res 1994 0.93
26 Analysis of the c-Ha-ras-1 gene for deletion, mutation, amplification and expression in lymph node metastases of human head and neck carcinomas. Br J Cancer 1990 0.93
27 c-myc, p53 and bcl-2, apoptosis-related genes in infiltrating breast carcinomas: evidence of a link between bcl-2 protein over-expression and a lower risk of metastasis and death in operable patients. Int J Cancer 1999 0.92
28 [Study of kinetoplast DNA of Trypansoma cruzi using restriction endonucleases]. C R Acad Sci Hebd Seances Acad Sci D 1975 0.90
29 c-erbB2 gene amplification and protein expression in ovarian epithelial tumors: evaluation of their respective prognostic significance by multivariate analysis. Int J Cancer 1995 0.90
30 Ultrastructural alterations of Trypanosoma cruzi kinetoplast induced by the interaction of a trypanocidal drug (hydroxystilbamidine) with the kinetoplast DNA. J Ultrastruct Res 1971 0.89
31 ATP-independent DNA topoisomerase II as potential drug target in trypanosomes. Biol Cell 1988 0.89
32 In vivo stimulation by antitumor drugs of the topoisomerase II induced cleavage sites in c-myc protooncogene. Biochem Biophys Res Commun 1986 0.89
33 Molecular organization of the kinetoplast DNA of Trypanosoma cruzi treated with berenil, a DNA interacting drug. J Ultrastruct Res 1972 0.89
34 [Presence of papillomavirus genomes and amplification of the c-myc and C-Ha-ras oncogenes in invasive cancers of the uterine cervix]. C R Acad Sci III 1984 0.88
35 [DNA ultrastructure of the kinetoplast of Trypanosoma cruzi cultivated in vitro]. C R Acad Sci Hebd Seances Acad Sci D 1969 0.88
36 Circular oligomers in mitochondrial DNA of human and beef nonmalignant thyroid glands. Proc Natl Acad Sci U S A 1972 0.88
37 Sequential modifications of topoisomerase I activity in a camptothecin-resistant cell line established by progressive adaptation. Biochem Pharmacol 1993 0.87
38 Structure and expression of c-myc and c-fos proto-oncogenes in thyroid carcinomas. Br J Cancer 1988 0.86
39 Prognostic value of c-myc proto-oncogene overexpression in early invasive carcinoma of the cervix. J Clin Oncol 1990 0.86
40 Association of c-erbB2-gene amplification with poor prognosis in non-inflammatory breast carcinomas but not in carcinomas of the inflammatory type. Int J Cancer 1994 0.85
41 N-myc genomic content and DNA ploidy in stage IVS neuroblastoma. J Clin Oncol 1991 0.85
42 Nuclear and kinetoplastic DNA from trypanosomes. J Protozool 1969 0.84
43 Study of molecular markers of resistance to m-AMSA in a human breast cancer cell line. Decrease of topoisomerase II and increase of both topoisomerase I and acidic glutathione S transferase. Biochem Pharmacol 1991 0.84
44 Restriction cleavage map of kinetoplast DNA minicircles from Trypanosoma equiperdum. Biochem Biophys Res Commun 1979 0.84
45 Expression of MDR1 and GST pi genes in 35 advanced neuroblastomas. Prog Clin Biol Res 1991 0.84
46 [Mitochondrial DNA of malignant cells]. Bull Cancer 1971 0.84
47 Analysis of topoisomerase II-mediated DNA cleavage of the c-myc gene during HL60 differentiation. FEBS Lett 1993 0.84
48 [Ultrastructure of DNA alterations of Trypanosoma cruzi kinetoplasts treated with ethidium bromide]. C R Acad Sci Hebd Seances Acad Sci D 1969 0.84
49 Inhibitors of trypanosome topoisomerases. Biochem Soc Trans 1986 0.83
50 Topoisomerase II-mediated DNA cleavage activity induced by ellipticines on the human tumor cell line N417. Biochem Pharmacol 1989 0.83
51 Stimulation of the topoisomerase II induced DNA cleavage sites in the c-myc protooncogene by antitumor drugs is associated with gene expression. Biochemistry 1989 0.83
52 Berenil induces the complete loss of kinetoblast DNA sequences in Trypanosoma equiperdum. Biochem Biophys Res Commun 1980 0.83
53 Cisplatin-induced apoptosis and p53 gene status in a cisplatin-resistant human ovarian carcinoma cell line. Int J Cancer 1996 0.82
54 p53 mediated tumor cell response to chemotherapeutic DNA damage: a preliminary study in matched pairs of breast cancer biopsies. Hum Pathol 1995 0.82
55 [Inhibition by ellipticine derivatives of the reactions catalysed by the topoisomerases: preferential inhibition of topoisomerase II]. C R Seances Acad Sci III 1983 0.82
56 Mitochondrial DNA from cells transformed by Avian myeloblastosis virus. Biochimie 1971 0.82
57 Mutation and abnormal expression of the p53 gene in the viral skin carcinogenesis of epidermodysplasia verruciformis. J Invest Dermatol 2001 0.82
58 Over-expression of MDR1 gene with no DNA amplification in a multiple-drug-resistant human ovarian carcinoma cell line. Int J Cancer 1989 0.81
59 Isolation and characterization of circular DNA molecules heterogeneous in size from a dyskinetoplastic strain of Trypanosoma equiperdum. Biochem Biophys Res Commun 1977 0.81
60 c-Ha-ras-1 polymorphism in human breast carcinomas: evidence for a normal distribution of alleles. Oncogene Res 1988 0.80
61 Specific inhibition by ethidium bromide of the incorporation of 3 H thymidine into the kinetoplastic DNA of Trypanosoma cruzi. Biochem Pharmacol 1970 0.80
62 Expression of the human fetal bac h19 gene in invasive cancers. Int J Oncol 1993 0.80
63 [Buschke-Löwenstein tumor. 3 vulvar localizations. Association with HPV-6 in one case]. Ann Dermatol Venereol 1985 0.79
64 [Disappearance of DNA from the kinetoplast of Trypanosoma Cruzi cultivated in the presence of ethidium bromide]. C R Acad Sci Hebd Seances Acad Sci D 1968 0.79
65 [Trypanocidal activity of some ellipticine derivatives against Trypanosoma cruzi cultured in vitro]. C R Acad Sci Hebd Seances Acad Sci D 1975 0.79
66 Clinical significance of multiple drug resistance in human cancers. Anticancer Res 1990 0.78
67 Tumorigenicity of cerebellar primitive neuro-ectodermal tumors in athymic mice correlates with poor prognosis in children. Int J Cancer 1996 0.78
68 [Partial purification and characterization of nuclear DNA-topoisomerases from trypanosomes (author's transl)]. C R Seances Acad Sci III 1982 0.78
69 A specific inhibitor of type I DNA-topoisomerase of Trypanosoma cruzi: dimethyl-hydroxy-ellipticinium. Biochem Biophys Res Commun 1983 0.78
70 [Oncocytes and oncocytomas. Histoenzymology, ultrastructure and description of the mitochondrial DNA]. Arch Anat Pathol (Paris) 1975 0.78
71 Characterization of the topoisomerase II-induced cleavage sites in the c-myc proto-oncogene. In vitro stimulation by the antitumoral intercalating drug mAMSA. Biochem Pharmacol 1986 0.78
72 [Importance of the extraction method in the isolation of DNA from Trypanosoma kinetoplast]. C R Acad Sci Hebd Seances Acad Sci D 1971 0.78
73 Characterization by sedimentation analysis of kinetoplast DNA from Trypanosoma cruzi at different stages of culture. Nucleic Acids Res 1979 0.78
74 [A DNA topoisomerase from trypanosomes able to catenate, decatenate and unknot DNA without ATP]. C R Acad Sci III 1986 0.77
75 [Mechanism of action of trypanocide diamidines. Importance of base composition in the berenil-polynucleotides association]. C R Acad Sci Hebd Seances Acad Sci D 1970 0.77
76 [Analysis of the expression of the oncogene c-myc in human breast adenocarcinoma]. C R Acad Sci III 1985 0.77
77 In vitro chemical eradication of small cell lung cancer: application in autologous bone marrow transplantation. Eur J Cancer Clin Oncol 1988 0.77
78 Prognostic value of MDR1 gene expression in neuroblastoma: results of a multivariate analysis. Prog Clin Biol Res 1994 0.76
79 Combined analysis of DNA ploidy index and N-myc genomic content in neuroblastoma. Prog Clin Biol Res 1991 0.76
80 Subunit organization of chromatin from trypanosoma cruzi sensitive and resistant to ethidium bromide. Mol Biochem Parasitol 1981 0.76
81 The early HPV16 proteins can regulate mRNA levels of cell cycle genes in human cervical carcinoma cells by p53-independent mechanisms. Virology 1998 0.76
82 [Expression of P-glycoprotein 170 (GP 170) and drug resistance in human cancers]. Bull Cancer 1990 0.75
83 [In vitro culture of clonogenic cells from various human tumors: chemosensitivity tests]. Bull Cancer 1984 0.75
84 Characterization of a new p53-mutated and hpv-negative human squamous-cell cervical carcinoma-derived cell-line. Int J Oncol 1995 0.75
85 [Chromosome anomalies in 2 cases of human ovarian cancer]. C R Acad Sci III 1986 0.75
86 [The expression of c-myb is strongly associated with the presence of estrogen and progesterone receptors in breast cancer]. C R Acad Sci III 1988 0.75
87 Nuclear and mitochondrial origin of rat liver double-stranded RNA. Biochimie 1975 0.75
88 [Fractionation and characterization of 2 satellite bands of DNA in Trypanosoma gambiense]. C R Acad Sci Hebd Seances Acad Sci D 1967 0.75
89 [High incidence of p53 mutations in primary and metastatic head and neck tumors. Frequent protein overexpression in normal epithelium]. Bull Cancer 1996 0.75
90 Effects of 9-hydroxy ellipticine on in vitro transcription of Trypanosoma cruzi DNAs. Biochem Biophys Res Commun 1977 0.75
91 Ultrastructural alterations of the nucleus and the kinetoplast of Trypanosoma cruzi exposed to ethidium bromide. Biochem Pharmacol 1970 0.75
92 The kinetoplast of DNA of Trypanosoma gambiense: comparison with the kDNA of Trypanosoma equiperdum. Biochimie 1981 0.75
93 [Study, at the gene level, of the activation of topoisomerase II by antitumor agents]. Pathol Biol (Paris) 1987 0.75
94 [Activation of N-myc oncogene and associated genes to chemoresistance, prognostic value for neuroblastoma]. Bull Cancer 1991 0.75
95 [Mode of action of trypanocide diamidines. Association of berenil with nucleic acids in vitro]. C R Acad Sci Hebd Seances Acad Sci D 1970 0.75
96 Decatenation of the kinetoplast DNA network of trypanosomes by a bacterial DNA-gyrase. Biochimie 1982 0.75
97 [Culture of clone-forming cells from human tumours and its practical applications (author's transl)]. Nouv Presse Med 1981 0.75
98 Mitochondrial DNA from cells transformed by adenoviruses and SV 40. Biochimie 1971 0.75
99 [Attempted demonstration of sequences common to kinetoplastic and nuclear DNA in Trypanosoma]. C R Acad Sci Hebd Seances Acad Sci D 1973 0.75
100 Culture of clonogenic cells from various human tumors: drug sensitivity assay. Eur J Cancer Clin Oncol 1983 0.75
101 [Amplification of the expression of the c-myc oncogene in bronchial epidermoid carcinoma in man]. C R Acad Sci III 1985 0.75
102 Interaction of DNA intercalator 3-nitrobenzothiazolo (3,2-a)quinolinium with DNA topoisomerases: a possible-mechanism for its biological activity. Mol Pharmacol 1990 0.75
103 Relapse from a stage IV-S neuroblastoma and N-myc amplification. Eur J Cancer Clin Oncol 1989 0.75
104 A human small cell lung carcinoma cell line, resistant to 4'-(9-acridinylamino)-methanesulfon-m-anisidide and cross-resistant to camptothecin with a high level of topoisomerase I. Biochem Pharmacol 1994 0.75
105 Soft agar clonogenic assay in human breast cancer. Neoplasma 1983 0.75