Published in Cell on May 05, 1989
Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors. EMBO J (1992) 4.69
The leucine-responsive regulatory protein, a global regulator of metabolism in Escherichia coli. Microbiol Rev (1994) 4.37
MyoD binds cooperatively to two sites in a target enhancer sequence: occupancy of two sites is required for activation. Proc Natl Acad Sci U S A (1990) 3.14
Binding of disparate transcriptional activators to nucleosomal DNA is inherently cooperative. Mol Cell Biol (1995) 2.73
Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene. Mol Cell Biol (1990) 2.12
Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells. Proc Natl Acad Sci U S A (2000) 1.94
A common motif within the negative regulatory regions of multiple factors inhibits their transcriptional synergy. Mol Cell Biol (2000) 1.90
Cooperative binding of estrogen receptor to imperfect estrogen-responsive DNA elements correlates with their synergistic hormone-dependent enhancer activity. EMBO J (1989) 1.82
Steroid hormone receptors and their regulation by phosphorylation. Biochem J (1996) 1.75
Two auxin-responsive domains interact positively to induce expression of the early indoleacetic acid-inducible gene PS-IAA4/5. Proc Natl Acad Sci U S A (1995) 1.66
The Oct-1 POU domain mediates interactions between Oct-1 and other POU proteins. Mol Cell Biol (1992) 1.59
Cooperative interactions between transcription factors Sp1 and OTF-1. Proc Natl Acad Sci U S A (1990) 1.57
Transcriptional synergy by the Epstein-Barr virus transactivator ZEBRA. J Virol (1992) 1.55
A synergistic increase in potency of a multimerized VP16 transcriptional activation domain. EMBO J (1992) 1.51
The ability of C/EBP beta but not C/EBP alpha to synergize with an Sp1 protein is specified by the leucine zipper and activation domain. Mol Cell Biol (1997) 1.47
In vivo transcription of a progesterone-responsive gene is specifically inhibited by a triplex-forming oligonucleotide. Nucleic Acids Res (1993) 1.46
Positive autoregulation of the yeast transcription factor Pdr3p, which is involved in control of drug resistance. Mol Cell Biol (1995) 1.45
Molecular mechanisms underlying origin and diversification of the angiosperm flower. Ann Bot (2007) 1.45
Properties of the DNA-binding domain of the Saccharomyces cerevisiae STE12 protein. Mol Cell Biol (1991) 1.44
Synergistic transcriptional enhancement does not depend on the number of acidic activation domains bound to the promoter. Proc Natl Acad Sci U S A (1991) 1.44
Phosphorylation stimulates the cooperative DNA-binding properties of the transcription factor OmpR. Proc Natl Acad Sci U S A (1997) 1.42
Cooperative binding of an Ultrabithorax homeodomain protein to nearby and distant DNA sites. Mol Cell Biol (1993) 1.38
Synergistic activation of a human promoter in vivo by transcription factor Sp1. Mol Cell Biol (1991) 1.34
Cooperative binding of the E2 protein of bovine papillomavirus to adjacent E2-responsive sequences. J Virol (1991) 1.32
Modulating the potency of an activator in a yeast in vitro transcription system. Mol Cell Biol (1994) 1.27
The class E floral homeotic protein SEPALLATA3 is sufficient to loop DNA in 'floral quartet'-like complexes in vitro. Nucleic Acids Res (2008) 1.23
Two types of antiprogestins identified by their differential action in transcriptionally active extracts from T47D cells. Nucleic Acids Res (1991) 1.20
A POU-A related region dictates DNA binding specificity of LFB1/HNF1 by orienting the two XL-homeodomains in the dimer. EMBO J (1992) 1.19
Transcriptional activation of a retrovirus enhancer by CBF (AML1) requires a second factor: evidence for cooperativity with c-Myb. J Virol (1996) 1.19
Synergistic transcriptional activation by CTF/NF-I and the estrogen receptor involves stabilized interactions with a limiting target factor. Mol Cell Biol (1991) 1.18
Interaction of DNA-binding proteins with a milk protein gene promoter in vitro: identification of a mammary gland-specific factor. Nucleic Acids Res (1991) 1.11
A novel retinoid X receptor-independent thyroid hormone response element is present in the human type 1 deiodinase gene. Mol Cell Biol (1995) 1.09
Cyclin E as a coactivator of the androgen receptor. J Cell Biol (2000) 1.08
Oestrogen facilitates the binding of ubiquitous and liver-enriched nuclear proteins to the apoVLDL II promoter in vivo. Nucleic Acids Res (1991) 1.07
Mechanism of estrogen receptor-dependent transcription in a cell-free system. Mol Cell Biol (1990) 1.07
Mechanism of synergistic transcriptional transactivation by the human glucocorticoid receptor. Proc Natl Acad Sci U S A (1991) 1.04
Hormone-induced progesterone receptor phosphorylation consists of sequential DNA-independent and DNA-dependent stages: analysis with zinc finger mutants and the progesterone antagonist ZK98299. Proc Natl Acad Sci U S A (1992) 1.03
A single amino acid change in CUP2 alters its mode of DNA binding. Mol Cell Biol (1990) 1.02
Ecdysterone receptor is a sequence-specific transcription factor involved in the developmental regulation of heat shock genes. Mol Cell Biol (1991) 1.02
Progesterone enhances target gene transcription by receptor free of heat shock proteins hsp90, hsp56, and hsp70. Mol Cell Biol (1991) 1.00
G protein-coupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17β-estradiol in cancer cells and cancer-associated fibroblasts. J Biol Chem (2012) 0.99
CBF, Myb, and Ets binding sites are important for activity of the core I element of the murine retrovirus SL3-3 in T lymphocytes. J Virol (1998) 0.99
Specificity of a retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoter: consequences of both retinoic acid and thyroid hormone receptor binding. Mol Cell Biol (1991) 0.99
A single GAL4 dimer can maximally activate transcription under physiological conditions. Proc Natl Acad Sci U S A (1995) 0.98
Thermodynamic analysis of progesterone receptor-promoter interactions reveals a molecular model for isoform-specific function. Proc Natl Acad Sci U S A (2007) 0.98
How different DNA sequences are recognized by a DNA-binding protein: effects of partial proteolysis. Nucleic Acids Res (1989) 0.96
Retracted Ligand-selective potentiation of rat mineralocorticoid receptor activation function 1 by a CBP-containing histone acetyltransferase complex. Mol Cell Biol (2002) 0.95
Cooperative DNA binding by the B-isoform of human progesterone receptor: thermodynamic analysis reveals strongly favorable and unfavorable contributions to assembly. Biochemistry (2006) 0.95
A critical role for chromatin in mounting a synergistic transcriptional response to GAL4-VP16. Mol Cell Biol (1994) 0.93
Thermodynamic dissection of progesterone receptor interactions at the mouse mammary tumor virus promoter: monomer binding and strong cooperativity dominate the assembly reaction. J Mol Biol (2008) 0.93
The essential DNA-binding protein sap1 of Schizosaccharomyces pombe contains two independent oligomerization interfaces that dictate the relative orientation of the DNA-binding domain. Mol Cell Biol (1995) 0.92
Purification and characterization of a novel factor which stimulates rat ribosomal gene transcription in vitro by interacting with enhancer and core promoter elements. Mol Cell Biol (1990) 0.90
ALU repeats in promoters are position-dependent co-response elements (coRE) that enhance or repress transcription by dimeric and monomeric progesterone receptors. Mol Endocrinol (2009) 0.88
Functional synergism in the carbohydrate-induced activation of liver-type pyruvate kinase gene expression. Biochem J (1995) 0.88
Regulation of thyroid hormone receptor-mediated transcription by a cytosol protein. Proc Natl Acad Sci U S A (1992) 0.88
Repressor to activator switch by mutations in the first Zn finger of the glucocorticoid receptor: is direct DNA binding necessary? Proc Natl Acad Sci U S A (1991) 0.87
Transcriptional regulation by triiodothyronine requires synergistic action of the thyroid receptor with another trans-acting factor. Mol Cell Biol (1992) 0.87
Fine-structure mutational analysis of a stage- and tissue-specific promoter element of the Drosophila glue gene Sgs-3. Mol Cell Biol (1990) 0.87
Arabidopsis SEPALLATA proteins differ in cooperative DNA-binding during the formation of floral quartet-like complexes. Nucleic Acids Res (2014) 0.86
Cooperative DNA binding and sequence discrimination by the Opaque2 bZIP factor. Plant Cell (1998) 0.85
Cooperative DNA binding of the bovine papillomavirus E2 transcriptional activator is antagonized by truncated E2 polypeptides. J Virol (1993) 0.83
Cooperative interaction of human HSF1 heat shock transcription factor with promoter DNA. Nucleic Acids Res (1994) 0.83
Transcriptional regulation of the apoAI gene by hepatic nuclear factor 4 in yeast. Nucleic Acids Res (1994) 0.83
A functional glucocorticoid-responsive unit composed of two overlapping inactive receptor-binding sites: evidence for formation of a receptor tetramer. Mol Cell Biol (1994) 0.82
Cooperative interaction of oestrogen receptor 'zinc finger' domain polypeptides on DNA binding. Biochem J (1995) 0.82
Na(+) and K(+) allosterically regulate cooperative DNA binding by the human progesterone receptor. Biochemistry (2010) 0.81
Selective photochemical treatment of oestrogen receptor in a Xenopus liver extract destroys hormone binding and transcriptional activation but not DNA binding. EMBO J (1990) 0.80
A view through a chromatin loop: insights into the ecdysone activation of early genes in Drosophila. Nucleic Acids Res (2014) 0.80
Synergistic transcriptional activation of the thyrotropin receptor promoter by cyclic AMP-responsive-element-binding protein and thyroid transcription factor 1. Biochem J (1995) 0.79
In silico modelling of hormone response elements. BMC Bioinformatics (2006) 0.79
Androgen receptor drives transcription of rat PACAP in gonadotrope cells. Mol Endocrinol (2013) 0.77
Stimulation of transcription in vitro from a liver-specific promoter by human glucocorticoid receptor (hGRalpha). Biochem J (1997) 0.77
Synergistic induction of promoters containing metal- and glucocorticoid-responsive elements. Nucleic Acids Res (1992) 0.75
Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem (1994) 10.75
Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science (1995) 10.42
Nuclear receptor coregulators: cellular and molecular biology. Endocr Rev (1999) 7.42
Specific 5' flanking sequences are required for faithful initiation of in vitro transcription of the ovalbumin gene. Proc Natl Acad Sci U S A (1981) 7.40
Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev (1995) 7.16
Sequence of chicken ovalbumin mRNA. Nature (1978) 6.73
Steroid receptor coactivator-1 is a histone acetyltransferase. Nature (1997) 6.15
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Dev (1997) 5.66
A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell (1999) 4.65
Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor. Genes Dev (1995) 4.07
Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. Science (1998) 3.85
The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development. Proc Natl Acad Sci U S A (2000) 3.55
Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proc Natl Acad Sci U S A (1988) 3.53
Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation. Cell (1988) 3.46
Nucleotide sequence homology at 12 intron--exon junctions in the chick ovalbumin gene. Nature (1978) 3.30
The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation. Mol Cell (2000) 3.23
A paracrine role for the epithelial progesterone receptor in mammary gland development. Proc Natl Acad Sci U S A (1998) 3.23
COUP transcription factor is a member of the steroid receptor superfamily. Nature (1989) 3.21
Temperature extremes and mortality from coronary heart disease and cerebral infarction in elderly Chinese. Lancet (1995) 3.18
The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development. Genes Dev (1999) 3.14
Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone. Proc Natl Acad Sci U S A (1993) 3.09
Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II). J Biol Chem (1992) 3.09
Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. Mol Endocrinol (1993) 2.89
Female steroid hormones and target cell nuclei. Science (1974) 2.87
Transcription of structural and intervening sequences in the ovalbumin gene and identification of potential ovalbumin mRNA precursors. Cell (1978) 2.87
Tissue-specific expression of a chicken calmodulin pseudogene lacking intervening sequences. Proc Natl Acad Sci U S A (1983) 2.86
Proteasome-dependent degradation of the human estrogen receptor. Proc Natl Acad Sci U S A (1999) 2.81
FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent. Nat Cell Biol (2001) 2.76
Molecular cloning of complementary DNA encoding the avian receptor for vitamin D. Science (1987) 2.71
Complete nucleotide sequence of the chicken chromosomal ovalbumin gene and its biological significance. Biochemistry (1981) 2.67
Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors. Mol Cell Biol (1992) 2.59
Ovomucoid intervening sequences specify functional domains and generate protein polymorphism. Cell (1980) 2.57
The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily. Mol Cell Biol (1999) 2.57
The ovalbumin gene: alleles created by mutations in the intervening sequences of the natural gene. Cell (1979) 2.56
Structure and expression of a chicken gene coding for U1 RNA. Cell (1981) 2.51
Steroid receptor family: structure and functions. Endocr Rev (1990) 2.49
Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): coming of age. Endocr Rev (1997) 2.43
Preparation and preliminary characterization of purified ovalbumin messenger RNA from the hen oviduct. Biochemistry (1975) 2.42
Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen. Mol Endocrinol (1997) 2.42
Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action. Recent Prog Horm Res (1997) 2.41
CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription. Proc Natl Acad Sci U S A (1996) 2.41
The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing. Mol Cell Biol (1995) 2.39
The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor. Cell (1992) 2.37
Actively transcribed genes are associated with the nuclear matrix. Nature (1984) 2.36
Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3. Mol Cell Biol (2000) 2.34
Dopaminergic and ligand-independent activation of steroid hormone receptors. Science (1991) 2.33
Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy. Proc Natl Acad Sci U S A (2000) 2.32
Studies on the mechanism of steroid hormone regulation of synthesis of specific proteins. Recent Prog Horm Res (1969) 2.31
A regulatory system for use in gene transfer. Proc Natl Acad Sci U S A (1994) 2.22
Definition of 5' and 3' structural boundaries of the chromatin domain containing the ovalbumin multigene family. J Biol Chem (1982) 2.22
Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells. Science (1988) 2.22
Point mutations in the human vitamin D receptor gene associated with hypocalcemic rickets. Science (1988) 2.15
Identification of a new brain-specific transcription factor, NURR1. Mol Endocrinol (1992) 2.11
The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors. J Biol Chem (1998) 2.08
The synthesis and properties of the complete complementary DNA transcript of ovalbumin mRNA. Biochemistry (1976) 2.08
The chick ovomucoid gene contains at least six intervening sequences. Nature (1979) 2.01
Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions. J Steroid Biochem Mol Biol (1999) 2.00
Transcription factors from oviduct and HeLa cells are similar. J Biol Chem (1981) 1.98
Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases. Proc Natl Acad Sci U S A (2000) 1.98
Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones. Mol Endocrinol (1996) 1.96
Identification of two factors required for transcription of the ovalbumin gene. Mol Cell Biol (1986) 1.96
Interactions between a DNA-binding transcription factor (COUP) and a non-DNA binding factor (S300-II). Cell (1987) 1.95
Variant human breast tumor estrogen receptor with constitutive transcriptional activity. Cancer Res (1991) 1.92
The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex. Cell (1990) 1.91
Neuronal basic helix-loop-helix proteins (NEX and BETA2/Neuro D) regulate terminal granule cell differentiation in the hippocampus. J Neurosci (2000) 1.91
Multiple mechanisms of chicken ovalbumin upstream promoter transcription factor-dependent repression of transactivation by the vitamin D, thyroid hormone, and retinoic acid receptors. J Biol Chem (1993) 1.89
The ovalbumin gene. In vitro enzymatic synthesis and characterization. J Biol Chem (1976) 1.89
Null mutation of mCOUP-TFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization. Genes Dev (1997) 1.88
Ligand-inducible and liver-specific target gene expression in transgenic mice. Nat Biotechnol (1997) 1.88
Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development. Proc Natl Acad Sci U S A (1997) 1.88
Ribonucleic acid precursors are associated with the chick oviduct nuclear matrix. Biochemistry (1982) 1.88