Binding of disparate transcriptional activators to nucleosomal DNA is inherently cooperative.

PubWeight™: 2.73‹?› | Rank: Top 1%

🔗 View Article (PMC 230365)

Published in Mol Cell Biol on March 01, 1995

Authors

C C Adams1, J L Workman

Author Affiliations

1: Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park 16802-4500.

Articles citing this

Nucleosome positioning and gene regulation: advances through genomics. Nat Rev Genet (2009) 6.50

Pioneer transcription factors: establishing competence for gene expression. Genes Dev (2011) 6.01

Global nucleosome occupancy in yeast. Genome Biol (2004) 5.49

Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome. Cell (2012) 3.80

Modification of enhancer chromatin: what, how, and why? Mol Cell (2013) 3.62

Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro. EMBO J (1996) 3.25

What controls nucleosome positions? Trends Genet (2009) 3.15

Collaborative competition mechanism for gene activation in vivo. Mol Cell Biol (2003) 3.10

Quantification of DNaseI-sensitivity by real-time PCR: quantitative analysis of DNaseI-hypersensitivity of the mouse beta-globin LCR. J Mol Biol (2001) 2.97

Binding of the winged-helix transcription factor HNF3 to a linker histone site on the nucleosome. EMBO J (1998) 2.81

The role of chromatin accessibility in directing the widespread, overlapping patterns of Drosophila transcription factor binding. Genome Biol (2011) 2.68

Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early Drosophila development. PLoS Genet (2011) 2.65

Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2F. Mol Cell Biol (1996) 2.46

Nucleosome-mediated cooperativity between transcription factors. Proc Natl Acad Sci U S A (2010) 2.30

Activation domain-specific and general transcription stimulation by native histone acetyltransferase complexes. Mol Cell Biol (1999) 2.11

Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming. Cell (2015) 2.06

The selection and function of cell type-specific enhancers. Nat Rev Mol Cell Biol (2015) 1.93

Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver. Genome Res (2010) 1.90

Chromatin opening and transactivator potentiation by RAP1 in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.87

Linking stochastic fluctuations in chromatin structure and gene expression. PLoS Biol (2013) 1.81

Chromatin remodeling during Saccharomyces cerevisiae ADH2 gene activation. Mol Cell Biol (1996) 1.81

Epigenetics of reprogramming to induced pluripotency. Cell (2013) 1.73

Incorporating nucleosomes into thermodynamic models of transcription regulation. Genome Res (2009) 1.72

Pioneer transcription factors in cell reprogramming. Genes Dev (2014) 1.71

Predicting transcription factor synergism. Nucleic Acids Res (2002) 1.66

Nucleosome positioning by the winged helix transcription factor HNF3. Genes Dev (1998) 1.65

Reactivation of developmentally silenced globin genes by forced chromatin looping. Cell (2014) 1.64

RBPJ, the major transcriptional effector of Notch signaling, remains associated with chromatin throughout mitosis, suggesting a role in mitotic bookmarking. PLoS Genet (2014) 1.61

Stimulation of transcription factor binding and histone displacement by nucleosome assembly protein 1 and nucleoplasmin requires disruption of the histone octamer. Mol Cell Biol (1995) 1.55

Stable co-occupancy of transcription factors and histones at the HIV-1 enhancer. EMBO J (1997) 1.51

Modulation of promoter occupancy by cooperative DNA binding and activation-domain function is a major determinant of transcriptional regulation by activators in vivo. Proc Natl Acad Sci U S A (1996) 1.48

A dynamic assembly of diverse transcription factors integrates activation and cell-type information for interleukin 2 gene regulation. Proc Natl Acad Sci U S A (1996) 1.42

Transcription Factors Encoded on Core and Accessory Chromosomes of Fusarium oxysporum Induce Expression of Effector Genes. PLoS Genet (2016) 1.39

Fast, long-range, reversible conformational fluctuations in nucleosomes revealed by single-pair fluorescence resonance energy transfer. Proc Natl Acad Sci U S A (2005) 1.38

Dynamics of nucleosome invasion by DNA binding proteins. J Mol Biol (2011) 1.35

High-throughput sequencing reveals a simple model of nucleosome energetics. Proc Natl Acad Sci U S A (2010) 1.34

Preparation of fully synthetic histone H3 reveals that acetyl-lysine 56 facilitates protein binding within nucleosomes. J Mol Biol (2011) 1.31

Dynamics and function of compact nucleosome arrays. Nat Struct Mol Biol (2009) 1.30

NF-E2 disrupts chromatin structure at human beta-globin locus control region hypersensitive site 2 in vitro. Mol Cell Biol (1996) 1.28

Granulocyte-macrophage colony-stimulating factor enhancer activation requires cooperation between NFAT and AP-1 elements and is associated with extensive nucleosome reorganization. Mol Cell Biol (2004) 1.21

Regulation of the nucleosome unwrapping rate controls DNA accessibility. Nucleic Acids Res (2012) 1.18

Role of chromatin and Xenopus laevis heat shock transcription factor in regulation of transcription from the X. laevis hsp70 promoter in vivo. Mol Cell Biol (1995) 1.16

The HNF1/HNF4-dependent We2 element of woodchuck hepatitis virus controls viral replication and can activate the N-myc2 promoter. J Virol (1996) 1.10

Nucleosome-mediated synergism between transcription factors on the mouse mammary tumor virus promoter. Proc Natl Acad Sci U S A (1997) 1.09

Linker histone protects linker DNA on only one side of the core particle and in a sequence-dependent manner. Proc Natl Acad Sci U S A (1998) 1.09

Nucleosomes accelerate transcription factor dissociation. Nucleic Acids Res (2013) 1.07

Nucleosome positioning in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (2011) 1.07

Mapping yeast transcriptional networks. Genetics (2013) 1.06

The binding of a Fos/Jun heterodimer can completely disrupt the structure of a nucleosome. EMBO J (1997) 1.05

Binding of HMG-I(Y) imparts architectural specificity to a positioned nucleosome on the promoter of the human interleukin-2 receptor alpha gene. Mol Cell Biol (2000) 1.04

Structural constraints in collaborative competition of transcription factors against the nucleosome. J Mol Biol (2011) 1.03

On the spontaneous stochastic dynamics of a single gene: complexity of the molecular interplay at the promoter. BMC Syst Biol (2010) 1.03

Synergism between hypersensitive sites confers long-range gene activation by the beta-globin locus control region. Proc Natl Acad Sci U S A (1997) 1.01

Occlusion of regulatory sequences by promoter nucleosomes in vivo. PLoS One (2011) 1.01

Post-translational modifications of histones that influence nucleosome dynamics. Chem Rev (2014) 0.99

Properties of ets-1 binding to chromatin and its effect on platelet factor 4 gene expression. Mol Cell Biol (2004) 0.99

Comprehensive prediction in 78 human cell lines reveals rigidity and compactness of transcription factor dimers. Genome Res (2013) 0.97

Peroxisome proliferator-activated receptor γ and C/EBPα synergistically activate key metabolic adipocyte genes by assisted loading. Mol Cell Biol (2013) 0.94

C/EBPbeta induces chromatin opening at a cell-type-specific enhancer. Mol Cell Biol (2008) 0.94

Differential nuclease sensitivity profiling of chromatin reveals biochemical footprints coupled to gene expression and functional DNA elements in maize. Plant Cell (2014) 0.91

Interaction of the 1alpha,25-dihydroxyvitamin D3 receptor at the distal promoter region of the bone-specific osteocalcin gene requires nucleosomal remodelling. Biochem J (2002) 0.91

Zelda overcomes the high intrinsic nucleosome barrier at enhancers during Drosophila zygotic genome activation. Genome Res (2015) 0.91

A SUMO-regulated activation function controls synergy of c-Myb through a repressor-activator switch leading to differential p300 recruitment. Nucleic Acids Res (2010) 0.90

New molecular bridge between RelA/p65 and NF-κB target genes via histone acetyltransferase TIP60 cofactor. J Biol Chem (2012) 0.90

A lattice model for transcription factor access to nucleosomal DNA. Biophys J (2010) 0.88

Regions of GAL4 critical for binding to a promoter in vivo revealed by a visual DNA-binding analysis. EMBO J (2003) 0.88

Chromatin-mediated restriction of nuclear factor 1/CTF binding in a repressed and hormone-activated promoter in vivo. Mol Cell Biol (2004) 0.87

Inducible nucleosome depletion at OREBP-binding-sites by hypertonic stress. PLoS One (2009) 0.86

Binding of PHF1 Tudor to H3K36me3 enhances nucleosome accessibility. Nat Commun (2013) 0.85

Binding of NF-κB to nucleosomes: effect of translational positioning, nucleosome remodeling and linker histone H1. PLoS Genet (2013) 0.85

A unified model for yeast transcript definition. Genome Res (2013) 0.84

Genome-wide profiling of nucleosome sensitivity and chromatin accessibility in Drosophila melanogaster. Nucleic Acids Res (2015) 0.84

Nucleosome Dancing at the Tempo of Histone Tail Acetylation. Genes (Basel) (2015) 0.83

GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler. Genome Biol (2016) 0.83

Ubiquitous nucleosome crowding in the yeast genome. Proc Natl Acad Sci U S A (2014) 0.82

Contribution of nucleosome binding preferences and co-occurring DNA sequences to transcription factor binding. BMC Genomics (2013) 0.82

Gammaretroviral vector integration occurs overwhelmingly within and near DNase hypersensitive sites. Hum Gene Ther (2011) 0.82

Transcriptional activators and activation mechanisms. Protein Cell (2011) 0.81

Functional roles of nucleosome stability and dynamics. Brief Funct Genomics (2014) 0.81

PPARG binding landscapes in macrophages suggest a genome-wide contribution of PU.1 to divergent PPARG binding in human and mouse. PLoS One (2012) 0.81

Paired hormone response elements predict caveolin-1 as a glucocorticoid target gene. PLoS One (2010) 0.81

Minireview: applications of next-generation sequencing on studies of nuclear receptor regulation and function. Mol Endocrinol (2012) 0.80

Identification of a novel distal control region upstream of the human steroidogenic acute regulatory protein (StAR) gene that participates in SF-1-dependent chromatin architecture. J Biol Chem (2010) 0.80

Beyond the histone tail: acetylation at the nucleosome dyad commands transcription. Nucleus (2013) 0.80

NF-κB and matrix-dependent regulation of osteopontin promoter activity in allylamine-activated vascular smooth muscle cells. Oxid Med Cell Longev (2012) 0.80

Chromatin-specific regulation of mammalian rDNA transcription by clustered TTF-I binding sites. PLoS Genet (2013) 0.79

Transcription factor oscillations induce differential gene expressions. Biophys J (2012) 0.79

Binding of the wheat basic leucine zipper protein EmBP-1 to nucleosomal binding sites is modulated by nucleosome positioning. Plant Cell (1996) 0.79

Nucleosome fragility is associated with future transcriptional response to developmental cues and stress in C. elegans. Genome Res (2016) 0.76

Mi2beta shows chromatin enzyme specificity by erasing a DNase I-hypersensitive site established by ACF. J Biol Chem (2009) 0.76

Understanding nucleosome dynamics and their links to gene expression and DNA replication. Nat Rev Mol Cell Biol (2017) 0.76

Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes. Elife (2017) 0.75

The proto-chromatosome: A fundamental subunit of chromatin? Nucleus (2016) 0.75

Receptor Signaling Directs Global Recruitment of Pre-existing Transcription Factors to Inducible Elements. Yale J Biol Med (2016) 0.75

Capitalizing on disaster: Establishing chromatin specificity behind the replication fork. Bioessays (2017) 0.75

Articles cited by this

Nuclease hypersensitive sites in chromatin. Annu Rev Biochem (1988) 13.48

The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product. Cell (1990) 9.37

Cloning of the p50 DNA binding subunit of NF-kappa B: homology to rel and dorsal. Cell (1990) 9.24

Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex. Science (1994) 7.17

Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection. Trends Genet (1992) 6.97

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex. Nature (1994) 6.55

A positive role for histone acetylation in transcription factor access to nucleosomal DNA. Cell (1993) 6.13

Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene. Cell (1987) 6.12

Facilitated binding of TATA-binding protein to nucleosomal DNA. Nature (1994) 5.95

Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators. Cell (1993) 5.91

ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor. Nature (1994) 5.75

DNA recognition by GAL4: structure of a protein-DNA complex. Nature (1992) 5.60

Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones. Cell (1987) 5.00

Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors. Cell (1987) 4.91

Sequence-specific positioning of nucleosomes over the steroid-inducible MMTV promoter. EMBO J (1987) 4.60

A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives. Nature (1990) 4.57

Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism. Genes Dev (1991) 4.54

Synergistic activation by the glutamine-rich domains of human transcription factor Sp1. Cell (1989) 4.49

Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element. Cell (1984) 4.42

Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase II. Cell (1987) 4.37

Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements. Cell (1993) 4.01

Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation. EMBO J (1993) 3.95

Nucleosome positioning modulates accessibility of regulatory proteins to the mouse mammary tumor virus promoter. Cell (1990) 3.75

A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation. EMBO J (1993) 3.74

Structure and function of the b/HLH/Z domain of USF. EMBO J (1994) 3.70

Nucleosome positioning can affect the function of a cis-acting DNA element in vivo. Nature (1990) 3.67

GAL4 derivatives function alone and synergistically with mammalian activators in vitro. Cell (1988) 3.67

Many transcription factors interact synergistically with steroid receptors. Science (1988) 3.49

Modularity in promoters and enhancers. Cell (1989) 3.47

Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription. Cell (1991) 3.46

Synergistic action of the glucocorticoid receptor with transcription factors. EMBO J (1988) 3.34

Facilitated binding of GAL4 and heat shock factor to nucleosomal templates: differential function of DNA-binding domains. Genes Dev (1991) 3.14

Transcription factor loading on the MMTV promoter: a bimodal mechanism for promoter activation. Science (1992) 3.13

Fos-Jun heterodimers and Jun homodimers bend DNA in opposite orientations: implications for transcription factor cooperativity. Cell (1991) 3.09

In vivo footprinting of rat TAT gene: dynamic interplay between the glucocorticoid receptor and a liver-specific factor. Cell (1991) 3.06

Decoding the nucleosome. Cell (1993) 2.99

How different eukaryotic transcriptional activators can cooperate promiscuously. Nature (1990) 2.91

The presence of nucleosomes on a DNA template prevents initiation by RNA polymerase II in vitro. Cell (1986) 2.88

Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements. Cell (1989) 2.69

Specific glucocorticoid receptor binding to DNA reconstituted in a nucleosome. EMBO J (1988) 2.66

Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter. Mol Cell Biol (1991) 2.56

Nucleosome core displacement in vitro via a metastable transcription factor-nucleosome complex. Science (1992) 2.40

Transcriptional regulation by the immediate early protein of pseudorabies virus during in vitro nucleosome assembly. Cell (1988) 2.23

Studies of the DNA binding properties of histone H4 amino terminus. Thermal denaturation studies reveal that acetylation markedly reduces the binding constant of the H4 "tail" to DNA. J Biol Chem (1993) 2.16

The transcriptionally-active MMTV promoter is depleted of histone H1. Nucleic Acids Res (1992) 2.16

Glucocorticoids are required for establishment and maintenance of an alteration in chromatin structure: induction leads to a reversible disruption of nucleosomes over an enhancer. EMBO J (1991) 2.14

The transactivation domain of Pho4 is required for nucleosome disruption at the PHO5 promoter. EMBO J (1994) 2.13

Transcriptional regulation of the HIV-1 promoter by NF-kappa B in vitro. Genes Dev (1992) 2.12

Multiple functions of nucleosomes and regulatory factors in transcription. Trends Biochem Sci (1993) 2.05

Nucleosome disruption at the yeast PHO5 promoter upon PHO5 induction occurs in the absence of DNA replication. Cell (1992) 2.02

An upstream transcription factor, USF (MLTF), facilitates the formation of preinitiation complexes during in vitro chromatin assembly. EMBO J (1990) 1.99

Nucleosome displacement in transcription. Cell (1993) 1.89

Ubiquitous transcription factor OTF-1 mediates induction of the MMTV promoter through synergistic interaction with hormone receptors. Cell (1991) 1.81

Irresistible force meets immovable object: transcription and the nucleosome. Cell (1991) 1.78

GAL4 disrupts a repressing nucleosome during activation of GAL1 transcription in vivo. Genes Dev (1993) 1.76

A histone-binding protein, nucleoplasmin, stimulates transcription factor binding to nucleosomes and factor-induced nucleosome disassembly. EMBO J (1994) 1.67

Role of the histone amino termini in facilitated binding of a transcription factor, GAL4-AH, to nucleosome cores. Mol Cell Biol (1994) 1.61

Cooperative interactions between transcription factors Sp1 and OTF-1. Proc Natl Acad Sci U S A (1990) 1.57

Synergistic activation of the HTLV1 LTR Ets-responsive region by transcription factors Ets1 and Sp1. EMBO J (1993) 1.57

Histones, nucleosomes and transcription. Curr Opin Genet Dev (1993) 1.56

Nucleosome-mediated disruption of transcription factor-chromatin initiation complexes at the mouse mammary tumor virus long terminal repeat in vivo. Mol Cell Biol (1994) 1.55

Synergism of closely adjacent estrogen-responsive elements increases their regulatory potential. J Mol Biol (1988) 1.45

Synergistic transcriptional enhancement does not depend on the number of acidic activation domains bound to the promoter. Proc Natl Acad Sci U S A (1991) 1.44

Differential repression of transcription factor binding by histone H1 is regulated by the core histone amino termini. EMBO J (1994) 1.43

Translational positioning of a nucleosomal glucocorticoid response element modulates glucocorticoid receptor affinity. Genes Dev (1993) 1.43

Nucleosome disruption by transcription factor binding in yeast. Science (1993) 1.38

A quick procedure for purification of functional recombinant proteins over-expressed in E.coli. Nucleic Acids Res (1991) 1.33

A critical role for heat shock transcription factor in establishing a nucleosome-free region over the TATA-initiation site of the yeast HSP82 heat shock gene. EMBO J (1993) 1.33

The role of activators in assembly of RNA polymerase II transcription complexes. Curr Opin Genet Dev (1994) 1.25

Assembly of RNA polymerase II preinitiation complexes before assembly of nucleosomes allows efficient initiation of transcription on nucleosomal templates. Mol Cell Biol (1988) 1.23

Nucleosome binding by the constitutive transcription factor Sp1. J Biol Chem (1994) 1.23

Differential binding of c-Myc and Max to nucleosomal DNA. Mol Cell Biol (1994) 1.19

Assembly of nucleosomes and chromatin in vitro. Methods Enzymol (1989) 1.12

Synergistic activation of transcription by multiple binding sites for NF-kappa B even in absence of co-operative factor binding to DNA. J Mol Biol (1990) 1.08

Glucocorticoid receptor DNA-binding specificity is increased by the organization of DNA in nucleosomes. Proc Natl Acad Sci U S A (1992) 1.00

Co-operative binding of the glucocorticoid receptor DNA binding domain is one of at least two mechanisms for synergism. J Mol Biol (1991) 0.94

Estrogen and progesterone receptor-binding sites on the chicken vitellogenin II gene: synergism of steroid hormone action. Mol Cell Biol (1988) 0.94

A critical role for chromatin in mounting a synergistic transcriptional response to GAL4-VP16. Mol Cell Biol (1994) 0.93

Analysis of the competition between nucleosome formation and transcription factor binding. J Biol Chem (1994) 0.85

Articles by these authors

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Genes Dev (1997) 8.35

Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex. Science (1994) 7.17

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. EMBO J (1996) 6.36

ATP-dependent chromatin-remodeling complexes. Mol Cell Biol (2000) 5.07

Transcriptional activators direct histone acetyltransferase complexes to nucleosomes. Nature (1998) 4.68

A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation. Cell (1998) 4.66

NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p. EMBO J (1999) 4.14

Promoter targeting and chromatin remodeling by the SWI/SNF complex. Curr Opin Genet Dev (2000) 4.11

Functional organization of the yeast SAGA complex: distinct components involved in structural integrity, nucleosome acetylation, and TATA-binding protein interaction. Mol Cell Biol (1999) 3.90

Histone acetyltransferase complexes stabilize swi/snf binding to promoter nucleosomes. Cell (2001) 3.54

Nucleosome mobilization catalysed by the yeast SWI/SNF complex. Nature (1999) 3.28

Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro. EMBO J (1996) 3.25

Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit. Science (2001) 3.17

Facilitated binding of GAL4 and heat shock factor to nucleosomal templates: differential function of DNA-binding domains. Genes Dev (1991) 3.14

The many HATs of transcription coactivators. Trends Biochem Sci (2000) 3.07

Expanded lysine acetylation specificity of Gcn5 in native complexes. J Biol Chem (1999) 2.91

The something about silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex. Genes Dev (2000) 2.77

Activation domain-mediated targeting of the SWI/SNF complex to promoters stimulates transcription from nucleosome arrays. Mol Cell (1999) 2.63

Persistent site-specific remodeling of a nucleosome array by transient action of the SWI/SNF complex. Science (1996) 2.63

The pseudorabies immediate early protein stimulates in vitro transcription by facilitating TFIID: promoter interactions. Genes Dev (1988) 2.60

Histone H3 specific acetyltransferases are essential for cell cycle progression. Genes Dev (2001) 2.55

The SAGA unfolds: convergence of transcription regulators in chromatin-modifying complexes. Trends Cell Biol (1998) 2.28

The ATM-related cofactor Tra1 is a component of the purified SAGA complex. Mol Cell (1998) 2.18

Experimental analysis of chromatin function in transcription control. Crit Rev Eukaryot Gene Expr (1994) 2.11

Activation domain-specific and general transcription stimulation by native histone acetyltransferase complexes. Mol Cell Biol (1999) 2.11

Perturbation of nucleosome core structure by the SWI/SNF complex persists after its detachment, enhancing subsequent transcription factor binding. Proc Natl Acad Sci U S A (1998) 2.09

Promoter targeting of chromatin-modifying complexes. Front Biosci (2001) 2.03

The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae. Mol Cell Biol (1999) 2.00

Distribution of acetylated histones resulting from Gal4-VP16 recruitment of SAGA and NuA4 complexes. EMBO J (2000) 1.92

Nucleosome displacement in transcription. Cell (1993) 1.89

Purified histone acetyltransferase complexes stimulate HIV-1 transcription from preassembled nucleosomal arrays. Proc Natl Acad Sci U S A (1998) 1.86

Identification and analysis of yeast nucleosomal histone acetyltransferase complexes. Methods (1998) 1.82

A histone-binding protein, nucleoplasmin, stimulates transcription factor binding to nucleosomes and factor-induced nucleosome disassembly. EMBO J (1994) 1.67

Analysis of nucleosome disruption by ATP-driven chromatin remodeling complexes. Methods Mol Biol (1999) 1.65

Regulation of DNA replication in vitro by the transcriptional activation domain of GAL4-VP16. Proc Natl Acad Sci U S A (1992) 1.64

The SWI/SNF complex creates loop domains in DNA and polynucleosome arrays and can disrupt DNA-histone contacts within these domains. Mol Cell Biol (1999) 1.61

Role of the histone amino termini in facilitated binding of a transcription factor, GAL4-AH, to nucleosome cores. Mol Cell Biol (1994) 1.61

A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex. Mol Cell (1999) 1.55

Stimulation of transcription factor binding and histone displacement by nucleosome assembly protein 1 and nucleoplasmin requires disruption of the histone octamer. Mol Cell Biol (1995) 1.55

Remodeling chromatin structures for transcription: what happens to the histones? Bioessays (1996) 1.54

SWI/SNF stimulates the formation of disparate activator-nucleosome complexes but is partially redundant with cooperative binding. J Biol Chem (1997) 1.53

The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1. Genes Dev (2001) 1.52

Stable co-occupancy of transcription factors and histones at the HIV-1 enhancer. EMBO J (1997) 1.51

Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex. Mol Cell Biol (1998) 1.50

Remodeling the chromatin structure of a nucleosome array by transcription factor-targeted trans-displacement of histones. EMBO J (1996) 1.46

In vitro analysis of transcription factor binding to nucleosomes and nucleosome disruption/displacement. Methods Enzymol (1996) 1.43

Differential repression of transcription factor binding by histone H1 is regulated by the core histone amino termini. EMBO J (1994) 1.43

Bookmarking genes for activation in condensed mitotic chromosomes. Bioessays (1998) 1.42

Recruitment of the SWI-SNF chromatin remodeling complex as a mechanism of gene activation by the glucocorticoid receptor tau1 activation domain. Mol Cell Biol (2000) 1.39

Sds3 (suppressor of defective silencing 3) is an integral component of the yeast Sin3[middle dot]Rpd3 histone deacetylase complex and is required for histone deacetylase activity. J Biol Chem (2000) 1.37

A novel H2A/H4 nucleosomal histone acetyltransferase in Tetrahymena thermophila. Mol Cell Biol (1999) 1.27

Nucleosome binding by the constitutive transcription factor Sp1. J Biol Chem (1994) 1.23

Transcriptional analysis of purified histone acetyltransferase complexes. Methods (1999) 1.20

Histone acetyltransferase complexes can mediate transcriptional activation by the major glucocorticoid receptor activation domain. Mol Cell Biol (1999) 1.18

Histone acetyltransferase complexes and their link to transcription. Crit Rev Eukaryot Gene Expr (1999) 1.16

Nucleosome binding by the polymerase I transactivator upstream binding factor displaces linker histone H1. Mol Cell Biol (1997) 1.11

Proteomic analysis of chromatin-modifying complexes in Saccharomyces cerevisiae identifies novel subunits. Biochem Soc Trans (2004) 1.09

Location and function of linker histones. Nat Struct Biol (1998) 1.09

H1-mediated repression of transcription factor binding to a stably positioned nucleosome. J Biol Chem (1997) 1.03

Analysis of transcription factor-mediated remodeling of nucleosomal arrays in a purified system. Methods (1997) 1.01

Transcriptionally active immediate-early protein of pseudorabies virus binds to specific sites on class II gene promoters. J Virol (1989) 1.00

Identification and analysis of native nucleosomal histone acetyltransferase complexes. Methods Mol Biol (1999) 1.00

Nucleoprotein hybridization: a method for isolating specific genes as high molecular weight chromatin. Biochemistry (1985) 0.93

Transcription. A lesson in sharing? Nature (1998) 0.84

Efficient solubilization and partial purification of sea urchin histone genes as chromatin. Biochemistry (1985) 0.83

Regulation of transcription by multisubunit complexes that alter nucleosome structure. Cold Spring Harb Symp Quant Biol (1998) 0.80

Binding of the wheat basic leucine zipper protein EmBP-1 to nucleosomal binding sites is modulated by nucleosome positioning. Plant Cell (1996) 0.79

Nucleosome cores and histone H1 in the binding of GAL4 derivatives and the reactivation of transcription from nucleosome templates in vitro. Cold Spring Harb Symp Quant Biol (1993) 0.78

Just the facts of chromatin transcription. Science (1998) 0.78

Analysis of activity and regulation of hGcn5, a human histone acetyltransferase. Methods Enzymol (1999) 0.75