Published in J Cell Biochem on August 01, 2015
Genes and Pathways Involved in Adult Onset Disorders Featuring Muscle Mitochondrial DNA Instability. Int J Mol Sci (2015) 0.78
DNA polymerase beta participates in mitochondrial DNA repair. Mol Cell Biol (2017) 0.76
The little big genome: the organization of mitochondrial DNA. Front Biosci (Landmark Ed) (2017) 0.75
Deep sequencing of mitochondrial genomes reveals increased mutation load in Friedreich's ataxia. Ann Clin Transl Neurol (2016) 0.75
Global deformation facilitates flipping of damaged 8-oxo-guanine and guanine in DNA. Nucleic Acids Res (2016) 0.75
Differential expression profile analysis of DNA damage repair genes in CD133(+)/CD133(-) colorectal cancer cells. Oncol Lett (2017) 0.75
Sequence and organization of the human mitochondrial genome. Nature (1981) 57.39
Predicting subcellular localization of proteins based on their N-terminal amino acid sequence. J Mol Biol (2000) 22.77
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet (2005) 16.79
PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization. Trends Biochem Sci (1999) 14.36
Computational method to predict mitochondrially imported proteins and their targeting sequences. Eur J Biochem (1996) 10.23
Protein import into mitochondria. Annu Rev Biochem (1997) 6.82
Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med (2000) 6.25
Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc Natl Acad Sci U S A (1988) 5.52
Mitochondria and cancer. Nat Rev Cancer (2012) 4.81
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. Nature (2000) 4.62
A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA. Nature (1996) 4.46
An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues. Proc Natl Acad Sci U S A (1974) 4.40
AP endonuclease-independent DNA base excision repair in human cells. Mol Cell (2004) 3.37
Endogenous DNA damage in humans: a review of quantitative data. Mutagenesis (2004) 3.02
Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision. Cell (1998) 2.41
Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs. Mol Biol Cell (1999) 2.26
The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase. Proc Natl Acad Sci U S A (2006) 2.17
The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis. Arch Biochem Biophys (2000) 2.16
Isolation and characterization of endonuclease VIII from Escherichia coli. Biochemistry (1994) 2.09
Base excision repair. Cold Spring Harb Perspect Biol (2013) 1.91
Functional human mitochondrial DNA polymerase gamma forms a heterotrimer. J Biol Chem (2005) 1.85
Mitochondrial targeting of human DNA glycosylases for repair of oxidative DNA damage. Nucleic Acids Res (1998) 1.83
Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair. Nature (2011) 1.80
Nuclear and mitochondrial DNA repair: similar pathways? Mitochondrion (2005) 1.73
Molecular and biological roles of Ape1 protein in mammalian base excision repair. DNA Repair (Amst) (2005) 1.72
Structure of a trapped endonuclease III-DNA covalent intermediate. EMBO J (2003) 1.72
Base excision repair. Adv Protein Chem (2004) 1.65
Interaction of the human DNA glycosylase NEIL1 with proliferating cell nuclear antigen. The potential for replication-associated repair of oxidized bases in mammalian genomes. J Biol Chem (2007) 1.63
The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity. Proc Natl Acad Sci U S A (2004) 1.52
NH2-terminal proline acts as a nucleophile in the glycosylase/AP-lyase reaction catalyzed by Escherichia coli formamidopyrimidine-DNA glycosylase (Fpg) protein. J Biol Chem (1997) 1.51
NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells. DNA Repair (Amst) (2006) 1.45
DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair. Nature (2011) 1.45
DNA repair in mammalian mitochondria: Much more than we thought? Environ Mol Mutagen (2010) 1.45
Mitochondrial DNA repair in aging and disease. Mech Ageing Dev (2008) 1.43
A role for iron-sulfur clusters in DNA repair. Curr Opin Chem Biol (2005) 1.34
Minimizing the damage: repair pathways keep mitochondrial DNA intact. Nat Rev Mol Cell Biol (2012) 1.30
Recent advances in the structural mechanisms of DNA glycosylases. Biochim Biophys Acta (2012) 1.30
DNA glycosylases: in DNA repair and beyond. Chromosoma (2011) 1.29
The Fpg/Nei family of DNA glycosylases: substrates, structures, and search for damage. Prog Mol Biol Transl Sci (2012) 1.22
Mitochondrial DNA nucleoid structure. Biochim Biophys Acta (2011) 1.21
Mitochondrial DNA damage and its consequences for mitochondrial gene expression. Biochim Biophys Acta (2012) 1.12
The role of endogenous and exogenous DNA damage and mutagenesis. Curr Opin Genet Dev (2004) 1.10
Uracil-DNA glycosylase: Structural, thermodynamic and kinetic aspects of lesion search and recognition. Mutat Res (2009) 1.09
DNA polymerase beta and mammalian base excision repair. Cold Spring Harb Symp Quant Biol (2000) 1.05
XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage. Environ Mol Mutagen (2011) 1.05
Mitochondria, energetics, epigenetics, and cellular responses to stress. Environ Health Perspect (2014) 1.03
MBD4 and TDG: multifaceted DNA glycosylases with ever expanding biological roles. Mutat Res (2012) 1.02
Structural characterization of a viral NEIL1 ortholog unliganded and bound to abasic site-containing DNA. J Biol Chem (2009) 1.01
DNA glycosylase encoded by MUTYH functions as a molecular switch for programmed cell death under oxidative stress to suppress tumorigenesis. Cancer Sci (2011) 0.99
Role of human DNA glycosylase Nei-like 2 (NEIL2) and single strand break repair protein polynucleotide kinase 3'-phosphatase in maintenance of mitochondrial genome. J Biol Chem (2011) 0.98
Structural studies of human alkyladenine glycosylase and E. coli 3-methyladenine glycosylase. Mutat Res (2000) 0.98
Functions of disordered regions in mammalian early base excision repair proteins. Cell Mol Life Sci (2010) 0.98
Neil3, the final frontier for the DNA glycosylases that recognize oxidative damage. Mutat Res (2012) 0.96
Uracil-DNA glycosylases-structural and functional perspectives on an essential family of DNA repair enzymes. Protein Sci (2014) 0.95
MUTYH DNA glycosylase: the rationale for removing undamaged bases from the DNA. Front Genet (2013) 0.92
MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides. DNA Repair (Amst) (2006) 0.91
DNA-mediated signaling by proteins with 4Fe-4S clusters is necessary for genomic integrity. J Am Chem Soc (2014) 0.91
Biochemical mapping of human NEIL1 DNA glycosylase and AP lyase activities. DNA Repair (Amst) (2012) 0.85
Oxidative DNA damage in disease--insights gained from base excision repair glycosylase-deficient mouse models. Environ Mol Mutagen (2014) 0.80
Alkyladenine DNA glycosylase (AAG) localizes to mitochondria and interacts with mitochondrial single-stranded binding protein (mtSSB). DNA Repair (Amst) (2013) 0.80
8-oxoguanine DNA glycosylases: one lesion, three subfamilies. Int J Mol Sci (2012) 0.78