PubRank

John P Lydon

Author PubWeight™ 110.10‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform. Proc Natl Acad Sci U S A 2003 3.30
2 Cre-mediated recombination in cell lineages that express the progesterone receptor. Genesis 2005 2.67
3 The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2. Science 2011 2.46
4 Conditional loss of uterine Pten unfailingly and rapidly induces endometrial cancer in mice. Cancer Res 2008 2.15
5 Foxa2 is essential for mouse endometrial gland development and fertility. Biol Reprod 2010 2.12
6 Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus. Nat Genet 2006 2.11
7 Bmp2 is critical for the murine uterine decidual response. Mol Cell Biol 2007 2.09
8 Reproductive functions of progesterone receptors. Recent Prog Horm Res 2002 1.82
9 WNT4 is a key regulator of normal postnatal uterine development and progesterone signaling during embryo implantation and decidualization in the mouse. FASEB J 2010 1.79
10 COUP-TFII mediates progesterone regulation of uterine implantation by controlling ER activity. PLoS Genet 2007 1.79
11 BMPR2 is required for postimplantation uterine function and pregnancy maintenance. J Clin Invest 2013 1.70
12 The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse. Dev Biol 2009 1.67
13 A novel LacZ reporter mouse reveals complex regulation of the progesterone receptor promoter during mammary gland development. Mol Endocrinol 2002 1.61
14 Identification of murine uterine genes regulated in a ligand-dependent manner by the progesterone receptor. Endocrinology 2005 1.59
15 Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. PLoS Genet 2013 1.56
16 NODAL in the uterus is necessary for proper placental development and maintenance of pregnancy. Biol Reprod 2012 1.52
17 Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. Mol Cell Biol 2006 1.52
18 A repressive role for prohibitin in estrogen signaling. Mol Endocrinol 2007 1.40
19 Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development. Mol Endocrinol 2002 1.37
20 Progesterone receptors in mammary gland development and tumorigenesis. J Mammary Gland Biol Neoplasia 2003 1.34
21 In vivo analysis of progesterone receptor action in the uterus during embryo implantation. Semin Cell Dev Biol 2008 1.34
22 Progesterone-dependent regulation of female reproductive activity by two distinct progesterone receptor isoforms. Steroids 2003 1.34
23 Transcriptional response of the murine mammary gland to acute progesterone exposure. Endocrinology 2008 1.33
24 Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease. Proc Natl Acad Sci U S A 2009 1.28
25 Peroxisome proliferator-activated receptor gamma is a target of progesterone regulation in the preovulatory follicles and controls ovulation in mice. Mol Cell Biol 2008 1.24
26 Research resource: Genome-wide profiling of progesterone receptor binding in the mouse uterus. Mol Endocrinol 2012 1.22
27 Gap junction communication between uterine stromal cells plays a critical role in pregnancy-associated neovascularization and embryo survival. Development 2008 1.22
28 Mouse models of implantation. Trends Endocrinol Metab 2007 1.20
29 A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis. Nat Med 2012 1.20
30 Epithelial progesterone receptor exhibits pleiotropic roles in uterine development and function. FASEB J 2011 1.19
31 Cell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cells. Cancer Res 2009 1.19
32 Progesterone involvement in breast development and tumorigenesis--as revealed by progesterone receptor "knockout" and "knockin" mouse models. Steroids 2003 1.19
33 Targeting RANKL to a specific subset of murine mammary epithelial cells induces ordered branching morphogenesis and alveologenesis in the absence of progesterone receptor expression. FASEB J 2010 1.17
34 The p160 steroid receptor coactivator 2, SRC-2, regulates murine endometrial function and regulates progesterone-independent and -dependent gene expression. Endocrinology 2007 1.15
35 Maternal heparin-binding-EGF deficiency limits pregnancy success in mice. Proc Natl Acad Sci U S A 2007 1.15
36 Stromal progesterone receptors mediate induction of Indian Hedgehog (IHH) in uterine epithelium and its downstream targets in uterine stroma. Endocrinology 2009 1.14
37 Signal transducer and activator of transcription-3 (Stat3) plays a critical role in implantation via progesterone receptor in uterus. FASEB J 2013 1.14
38 WNTs in the neonatal mouse uterus: potential regulation of endometrial gland development. Biol Reprod 2010 1.12
39 Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells. Development 2013 1.11
40 Revealing progesterone's role in uterine and mammary gland biology: insights from the mouse. Semin Reprod Med 2005 1.07
41 Steroid receptor coactivator 2 is required for female fertility and mammary morphogenesis: insights from the mouse, relevance to the human. Nucl Recept Signal 2007 1.06
42 Enhanced sexual behaviors and androgen receptor immunoreactivity in the male progesterone receptor knockout mouse. Endocrinology 2005 1.05
43 A mouse model to dissect progesterone signaling in the female reproductive tract and mammary gland. Genesis 2010 1.05
44 CDH1 is essential for endometrial differentiation, gland development, and adult function in the mouse uterus. Biol Reprod 2012 1.04
45 Ablation of Indian hedgehog in the murine uterus results in decreased cell cycle progression, aberrant epidermal growth factor signaling, and increased estrogen signaling. Biol Reprod 2010 1.03
46 Activin-like kinase 2 functions in peri-implantation uterine signaling in mice and humans. PLoS Genet 2013 1.02
47 Epithelial-stromal interaction and progesterone receptors in the mouse uterus. Semin Reprod Med 2010 1.01
48 VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy. EMBO Mol Med 2013 1.00
49 Progesterone receptor and Stat5 signaling cross talk through RANKL in mammary epithelial cells. Mol Endocrinol 2013 1.00
50 Intact progesterone receptors are essential to counteract the proliferative effect of estradiol in a genetically engineered mouse model of endometriosis. Fertil Steril 2004 0.99
51 Progesterone receptors: a key for neuroprotection in experimental stroke. Endocrinology 2012 0.99
52 Constitutive activation of smoothened leads to female infertility and altered uterine differentiation in the mouse. Biol Reprod 2010 0.98
53 Progesterone suppresses the mTOR pathway and promotes generation of induced regulatory T cells with increased stability. Eur J Immunol 2012 0.98
54 Suppression of ERalpha activity by COUP-TFII is essential for successful implantation and decidualization. Mol Endocrinol 2010 0.97
55 The differences in neuroprotective efficacy of progesterone and medroxyprogesterone acetate correlate with their effects on brain-derived neurotrophic factor expression. Endocrinology 2009 0.96
56 Connective tissue growth factor is required for normal follicle development and ovulation. Mol Endocrinol 2011 0.96
57 Liver receptor homolog-1 is essential for pregnancy. Nat Med 2013 0.95
58 From the ranks of mammary progesterone mediators, RANKL takes the spotlight. Mol Cell Endocrinol 2011 0.94
59 Bone growth and turnover in progesterone receptor knockout mice. Endocrinology 2008 0.93
60 The Synergistic Effect of Conditional Pten Loss and Oncogenic K-ras Mutation on Endometrial Cancer Development Occurs via Decreased Progesterone Receptor Action. J Oncol 2009 0.91
61 Nuclear receptor coactivator-6 attenuates uterine estrogen sensitivity to permit embryo implantation. Dev Cell 2012 0.91
62 Progesterone's role in mammary gland development and tumorigenesis as disclosed by experimental mouse genetics. Breast Cancer Res 2002 0.90
63 Uterine-specific loss of Tsc2 leads to myometrial tumors in both the uterus and lungs. Mol Endocrinol 2013 0.90
64 Progesterone signaling inhibits cervical carcinogenesis in mice. Am J Pathol 2013 0.90
65 Estrogen-regulated prohibitin is required for mouse uterine development and adult function. Endocrinology 2011 0.89
66 Progesterone and HMOX-1 promote fetal growth by CD8+ T cell modulation. J Clin Invest 2015 0.86
67 Critical tumor suppressor function mediated by epithelial Mig-6 in endometrial cancer. Cancer Res 2013 0.86
68 Targeting reverse tetracycline-dependent transactivator to murine mammary epithelial cells that express the progesterone receptor. Genesis 2007 0.86
69 GATA2 is expressed at critical times in the mouse uterus during pregnancy. Gene Expr Patterns 2012 0.86
70 ERBB receptor feedback inhibitor 1 regulation of estrogen receptor activity is critical for uterine implantation in mice. Biol Reprod 2009 0.85
71 The pattern of beta-catenin responsiveness within the mammary gland is regulated by progesterone receptor. Development 2007 0.85
72 Alterations in Wnt-β-catenin and Pten signalling play distinct roles in endometrial cancer initiation and progression. J Pathol 2013 0.85
73 Steroid receptor coactivator 2 is essential for progesterone-dependent uterine function and mammary morphogenesis: insights from the mouse--implications for the human. J Steroid Biochem Mol Biol 2006 0.85
74 Dysregulation of uterine signaling pathways in progesterone receptor-Cre knockout of dicer. Mol Endocrinol 2012 0.84
75 Integrated chromatin immunoprecipitation sequencing and microarray analysis identifies FOXA2 target genes in the glands of the mouse uterus. FASEB J 2013 0.84
76 Generation of a mouse for conditional excision of progesterone receptor. Genesis 2006 0.84
77 β-Catenin activation contributes to the pathogenesis of adenomyosis through epithelial-mesenchymal transition. J Pathol 2013 0.84
78 Stem cells: Cues from steroid hormones. Nature 2010 0.83
79 Uterine development and fertility are dependent on gene dosage of the nuclear receptor coregulator REA. Endocrinology 2012 0.83
80 Role of the progesterone receptor (PR) in susceptibility of mouse mammary gland to 7,12-dimethylbenz[a]anthracene-induced hormone-independent preneoplastic lesions in vitro. Cancer Lett 2002 0.82
81 Hormonal defect in maspin heterozygous mice reveals a role of progesterone in pubertal ductal development. Mol Endocrinol 2004 0.82
82 Targeting iCre expression to murine progesterone receptor cell-lineages using bacterial artificial chromosome transgenesis. Genesis 2006 0.81
83 Functional role of progestin and the progesterone receptor in the suppression of spermatogenesis in rodents. Andrology 2013 0.81
84 A mouse model for endometrioid ovarian cancer arising from the distal oviduct. Int J Cancer 2014 0.81
85 Loss of APC function in mesenchymal cells surrounding the Müllerian duct leads to myometrial defects in adult mice. Mol Cell Endocrinol 2011 0.80
86 Fibroblast growth factor receptor two (FGFR2) regulates uterine epithelial integrity and fertility in mice. Biol Reprod 2014 0.80
87 Progesterone-action in the murine uterus and mammary gland requires steroid receptor coactivator 2: relevance to the human. Front Biosci 2007 0.80
88 Activated AKT pathway promotes establishment of endometriosis. Endocrinology 2014 0.80
89 A mouse transgenic approach to induce β-catenin signaling in a temporally controlled manner. Transgenic Res 2010 0.80
90 A murine uterine transcriptome, responsive to steroid receptor coactivator-2, reveals transcription factor 23 as essential for decidualization of human endometrial stromal cells. Biol Reprod 2014 0.78
91 Loss of CDH1 and Pten accelerates cellular invasiveness and angiogenesis in the mouse uterus. Biol Reprod 2013 0.78
92 Paracrine-rescued lobulogenesis in chimeric outgrowths comprising progesterone-receptor-null mammary epithelium and redirected wild-type testicular cells. J Cell Sci 2013 0.78
93 A role for site-specific phosphorylation of mouse progesterone receptor at serine 191 in vivo. Mol Endocrinol 2014 0.75
94 Correction: Acceleration of the Glycolytic Flux by Steroid Receptor Coactivator-2 Is Essential for Endometrial Decidualization. PLoS Genet 2015 0.75
95 Correction: Perturbing the Cellular Levels of Steroid Receptor Coactivator-2 Impairs Murine Endometrial Function. PLoS One 2015 0.75
96 Application of 13C isotope labeling using liquid chromatography mass spectrometry (LC-MS) to determining phosphate-containing metabolic incorporation. J Mass Spectrom 2013 0.75
97 Application of (13) C isotope labeling using liquid chromatography mass spectrometry (LC-MS) to determining phosphate-containing metabolic incorporation. J Mass Spectrom 2015 0.75