Published in Nature on December 02, 1982
Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin. J Exp Med (1983) 3.52
Organization of the transcriptional unit of a human class II histocompatibility antigen: HLA-DR heavy chain. Nucleic Acids Res (1983) 1.65
Delineation of an immunoregulatory amplifier population recognizing autologous Ia molecules. Analysis with human T cell clones. J Exp Med (1984) 1.49
Interleukin-2 can prevent and reverse antigen-induced unresponsiveness in cloned human T lymphocytes. Immunology (1988) 1.48
Immunoregulatory T cell circuits in man. Alloantigen-primed inducer T cells activate alloantigen-specific suppressor T cells in the absence of the initial antigenic stimulus. J Exp Med (1983) 1.30
Generation of antigen receptor-specific suppressor T cell clones in man. J Exp Med (1986) 0.92
Comprehensive analysis of MHC-II expression in healthy human skin. Immunol Cell Biol (2007) 0.92
Characterization of human T8+ suppressor and contrasuppressor cells, separated by the lectin Vicia villosa. Immunology (1988) 0.89
Analysis of T-cell cultures and clones from a patient with classic rheumatoid arthritis--evidence for the existence of autoreactive T-cell clones in blood and synovial fluid. Rheumatol Int (1984) 0.87
A circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment. Ann Rheum Dis (2014) 0.86
MHC-restricted minimal regulatory circuit initiated by a class II-autoreactive T cell clone. J Exp Med (1987) 0.85
Functional characterization of a regulatory human T-cell subpopulation increasing during autologous MLR. Immunology (1986) 0.84
A cellular deficiency in the rheumatoid one-way mixed lymphocyte reaction. Clin Exp Immunol (1988) 0.83
Normal Lyt-1+2- T cells have the unique capacity to respond to syngeneic autoreactive T cells. Demonstration of a T cell network. J Exp Med (1985) 0.80
Autoreactive CD4- CD8- alpha beta T cells to vaccinate adjuvant arthritis. Immunology (1998) 0.79
Prospective study of lymphocyte subsets in subjects genetically susceptible to type 1 (insulin-dependent) diabetes. Diabetologia (1984) 0.79
Suppressor T cell growth and differentiation. Identification of a cofactor required for suppressor T cell function and distinct from interleukin 2. J Exp Med (1984) 0.78
Immunoglobulin production in the autologous MLR: target of the suppressor-amplifier circuit. Clin Exp Immunol (1986) 0.78
T cell blast stimulation of MLR: role of interleukin 1 and interleukin 2. Clin Exp Immunol (1988) 0.77
CD4+ CD45R- suppressor-inducer T-cell clones: requirements for cellular interaction, proliferation and lymphokines for the induction of suppression in peripheral blood mononuclear cells. Immunology (1990) 0.75
In vitro induction of HBsAg-specific CD8 CD11 human suppressor T cells. Immunology (1987) 0.75
Human T-cell hybrids with HLA-restricted proliferative response to Epstein-Barr virus-infected B cells. Immunology (1984) 0.75
Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints. EMBO J (1998) 5.25
Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin. J Exp Med (1983) 3.52
Epithelial cells expressing aberrant MHC class II determinants can present antigen to cloned human T cells. Nature (1985) 3.11
PIB is a non-specific imaging marker of amyloid-beta (Abeta) peptide-related cerebral amyloidosis. Brain (2007) 2.88
Human T-cell clones recognize chemically synthesized peptides of influenza haemagglutinin. Nature (1982) 2.84
T lymphocytes respond to solid-phase antigen: a novel approach to the molecular analysis of cellular immunity. Immunology (1986) 2.45
Structural model of HLA-DR1 restricted T cell antigen recognition. Cell (1988) 2.41
Antigen-specific human T lymphocyte clones: induction, antigen specificity, and MHC restriction of influenza virus-immune clones. J Immunol (1982) 2.30
Tolerance of T-cell clones is associated with membrane antigen changes. Nature (1983) 2.10
Mapping of T cell epitopes using recombinant antigens and synthetic peptides. EMBO J (1987) 2.09
Biological activity of protein antigens isolated from Mycobacterium tuberculosis culture filtrate. Infect Immun (1988) 2.01
Analysis of the antigen specificity of influenza haemagglutinin-immune human T lymphocyte clones: identification of an immunodominant region for T cells. Immunology (1983) 1.88
Binary and ternary complexes between T-cell receptor, class II MHC and superantigen in vitro. Nature (1994) 1.79
Intranasal exposure to protein antigen induces immunological tolerance mediated by functionally disabled CD4+ T cells. J Immunol (1999) 1.77
Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice. J Exp Med (1993) 1.71
Which guesstimate is the best guesstimate? Predicting chemotherapeutic outcomes. Nat Med (1997) 1.66
A novel approach to the identification of T-cell epitopes in Mycobacterium tuberculosis using human T-lymphocyte clones. Immunology (1987) 1.63
Antigen-specific human T lymphocyte clones: viral antigen specificity of influenza virus-immune clones. J Immunol (1982) 1.49
Interleukin-2 can prevent and reverse antigen-induced unresponsiveness in cloned human T lymphocytes. Immunology (1988) 1.48
Investigation of early T cell activation: analysis of the effect of specific antigen, interleukin 2 and monoclonal antibodies on intracellular free calcium concentration. Eur J Immunol (1985) 1.41
Induction of a type 1 immune response to a recombinant antigen from Mycobacterium tuberculosis expressed in Mycobacterium vaccae. Infect Immun (1997) 1.41
Major histocompatibility complex independent clonal T cell anergy by direct interaction of Staphylococcus aureus enterotoxin B with the T cell antigen receptor. J Exp Med (1992) 1.37
Evidence for a superantigen mediated process in Kawasaki disease. Arch Dis Child (1995) 1.34
The identification of T cell epitopes in Mycobacterium tuberculosis using human T lymphocyte clones. Lepr Rev (1986) 1.32
Induction of specific clonal anergy in human T lymphocytes by Staphylococcus aureus enterotoxins. Proc Natl Acad Sci U S A (1990) 1.30
In vitro influenza virus-specific antibody production in man: antigen-specific and HLA-restricted induction of helper activity mediated by cloned human T lymphocytes. J Immunol (1982) 1.29
Association between HLA-DR antigens and helper cell activity in the control of dental caries. Nature (1981) 1.27
Regulation of house dust mite responses by intranasally administered peptide: transient activation of CD4+ T cells precedes the development of tolerance in vivo. Int Immunol (1996) 1.26
Clonal analysis of differential lymphokine production in peptide and superantigen induced T cell anergy. Int Immunol (1991) 1.24
Effect of natural polymorphism at residue 86 of the HLA-DR beta chain on peptide binding. J Immunol (1991) 1.22
A comparative investigation of the generation of specific T cell-helper function induced by Streptococcus mutans in monkeys and mice. J Immunol (1980) 1.21
Differential pattern of T cell recognition of the 65-kDa mycobacterial antigen following immunization with the whole protein or peptides. Eur J Immunol (1989) 1.20
Human CD4+ T-cell repertoire of responses to influenza A virus hemagglutinin after recent natural infection. J Virol (1995) 1.19
Orientation of epitopes influences the immunogenicity of synthetic peptide dimers. Eur J Immunol (1988) 1.18
Structural analysis of a peptide--HLA class II complex: identification of critical interactions for its formation and recognition by T cell receptor. Int Immunol (1989) 1.18
Serrate1-induced notch signalling regulates the decision between immunity and tolerance made by peripheral CD4(+) T cells. Int Immunol (2000) 1.17
Generation of specfic T-cell suppressor function induced by Streptococcus mutans in monkeys and mice. Infect Immun (1979) 1.15
Cloned human T lymphocytes reactive with Dermatophagoides farinae (house dust mite): a comparison of T- and B-cell antigen recognition. Immunology (1987) 1.15
Functional evidence for a monoclonal antibody that binds to the human IL-4 receptor. Immunology (1988) 1.12
Essential requirement for major histocompatibility complex recognition in T-cell tolerance induction. Nature (1984) 1.07
Peptide-mediated modulation of T-cell allorecognition. Proc Natl Acad Sci U S A (1988) 1.05
The dissociation of interleukin-2 production and antigen-specific helper activity by clonal analysis. Immunology (1983) 1.04
MHC class II restriction specificity of cloned human T lymphocytes reactive with Dermatophagoides farinae (house dust mite). Immunology (1988) 1.03
A novel T-lymphocyte molecule that may function in the induction of self-tolerance and MHC-restriction within the human thymic microenvironment. Immunology (1988) 1.02
CD28 mRNA rapidly decays when activated T cells are functionally anergized with specific peptide. Int Immunol (1993) 1.02
SB-restricted presentation of influenza and herpes simplex virus antigens to human T-lymphocyte clones. Nature (1983) 1.02
In vivo clonal dominance and limited T-cell receptor usage in human CD4+ T-cell recognition of house dust mite allergens. Proc Natl Acad Sci U S A (1993) 1.02
Functional inactivation of Dermatophagoides spp. (house dust mite) reactive human T-cell clones. Clin Exp Allergy (1991) 1.01
An in vitro model of allergen-dependent IgE synthesis by human B lymphocytes: comparison of the response of an atopic and a non-atopic individual to Dermatophagoides spp. (house dust mite). Immunology (1989) 0.98
The immunology of influenza. Br Med Bull (1985) 0.97
Localization of the immunologic activity in the superantigen Staphylococcal enterotoxin B using truncated recombinant fusion proteins. J Immunol (1992) 0.97
Co-recognition of endogenous antigens with HLA-DR1 by alloreactive human T cell clones. J Immunol (1989) 0.96
Mapping T cell recognition: the identification of a T cell receptor residue critical to the specific interaction with an influenza hemagglutinin peptide. Eur J Immunol (1995) 0.96
Peptide-induced nonresponsiveness of HLA-DP restricted human T cells reactive with Dermatophagoides spp. (house dust mite). J Allergy Clin Immunol (1992) 0.96
The specificity and regulation of T-cell responsiveness to allergens. Annu Rev Immunol (1991) 0.95
Rheumatoid arthritis synovial T cells regulate transcription of several genes associated with antigen-induced anergy. J Clin Invest (2001) 0.94
Antigen-induced neutrophil chemotactic factor from cloned human T lymphocytes. Immunology (1988) 0.93
Uncoupling of cytokine mRNA expression and protein secretion during the induction phase of T cell anergy. J Immunol (1992) 0.93
Immunosuppressant deoxyspergualin inhibits antigen processing in monocytes. J Immunol (1994) 0.93
Analysis of human T cell responses to the group II allergen of Dermatophagoides species: localization of major antigenic sites. J Allergy Clin Immunol (1993) 0.92
T-cell responses to allergens: epitope-specificity and clinical relevance. Immunol Today (1996) 0.91
Overlapping T-cell epitopes in the group I allergen of Dermatophagoides species restricted by HLA-DP and HLA-DR class II molecules. J Allergy Clin Immunol (1994) 0.91
Clonal analysis of the atopic immune response to the group 2 allergen of Dermatophagoides spp.: identification of HLA-DR and -DQ restricted T cell epitopes. Int Immunol (1993) 0.91
A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues. J Pathol (2004) 0.91
Antigen specificity and function of human T lymphocyte clones reactive with mycobacteria. Br Med Bull (1988) 0.91
Effects of platelet-derived growth factor and epidermal growth factor on antigen-induced proliferation of human T-cell lines. Immunology (1985) 0.91
Inhibition of T cell proliferation by antibodies to synthetic peptides. Eur J Immunol (1984) 0.91
Human helper T-cell clones that recognize different influenza hemagglutinin determinants are restricted by different HLA-D region epitopes. Immunogenetics (1984) 0.90
T-cell activation by anti-idiotypic antibody: evidence for the internal image. Immunology (1987) 0.90
Partial characterization of murine and monkey helper factor to a streptococcal antigen. Immunology (1980) 0.89
Induction of anergy in human T helper 0 cells by stimulation with altered T cell antigen receptor ligands. J Immunol (1996) 0.89
Cholinergic neurons of the chicken ciliary ganglion contain somatostatin. Neuroscience (1988) 0.89
Induction of tolerance via the respiratory mucosa. Int Arch Allergy Immunol (1998) 0.89
Identification of two binding sites in staphylococcal enterotoxin B that confer specificity for TCR V beta gene products. Int Immunol (1994) 0.89
T cell activation by anti-idiotypic antibody: mechanism of interaction with antigen-reactive T cells. Eur J Immunol (1987) 0.88
Antigen-specific human T-lymphocyte clones. Genetic restriction of influenza virus-specific responses to HLA-D region genes. Hum Immunol (1982) 0.88
Contribution of T-cell receptor-contacting and peptide-binding residues of the class II molecule HLA-DR4 Dw10 to serologic and antigen-specific T-cell recognition. Hum Immunol (1991) 0.87
Characterization of the specificity and duration of T cell tolerance to intranasally administered peptides in mice: a role for intramolecular epitope suppression. Int Immunol (1997) 0.86
Direct evidence for a functional role of HLA-DRB1 and -DRB3 gene products in the recognition of Dermatophagoides spp. (house dust mite) by helper T lymphocytes. Int Immunol (1990) 0.86
Polyclonal and clonal analysis of human CD4+ T-lymphocyte responses to nut extracts. Immunology (1995) 0.86
Regulation of T cell function in mucosal tolerance. Immunol Cell Biol (1997) 0.86
Prediction of murine MHC class I epitopes in a major house dust mite allergen and induction of T1-type CD8+ T cell responses. Int Immunol (1997) 0.85
Antigen-specific helper factor reacts with antibodies to human beta 2 microglobulin. J Immunol (1981) 0.85
Characterisation of major and minor Dermatophagoides allergens in canine atopic dermatitis. Res Vet Sci (2001) 0.85
Stress proteins and the immune response to mycobacteria--antigens as virulence factors? Antonie Van Leeuwenhoek (1988) 0.85
Notch signalling in the regulation of peripheral immunity. Immunol Rev (2001) 0.85
Human CD4+ T-cell recognition of influenza A virus hemagglutinin after subunit vaccination. J Virol (1996) 0.85
Expression of Th1, Th2 and immunosuppressive cytokine gene transcripts in canine atopic dermatitis. Clin Exp Allergy (2002) 0.85
Generation of monoclonal antibodies against a human T cell receptor beta chain expressed in transgenic mice. Hybridoma (1992) 0.84
Differential induction of the NF-AT complex during restimulation and the induction of T-cell anergy. Hum Immunol (1995) 0.84
Inositol lipid metabolism in human T lymphocytes activated via the T3 complex. Immunology (1987) 0.84
Immunological tolerance to inhaled antigen. Am J Respir Crit Care Med (2000) 0.84
T-cell regulation of peripheral tolerance and immunity: the potential role for Notch signalling. Immunology (2000) 0.84
Altered T cell ligands derived from a major house dust mite allergen enhance IFN-gamma but not IL-4 production by human CD4+ T cells. J Immunol (1996) 0.84
Immunochemical properties of antigen-specific monkey T-cell suppressor factor induced with a Streptococcus mutans antigen. Infect Immun (1980) 0.83
Direct evaluation of antigen binding to human T lymphocyte clones: involvement of major histocompatibility complex products in antigen binding. Eur J Immunol (1984) 0.83
T-helper 1, T-helper 2 and immunosuppressive cytokines in canine atopic dermatitis. Vet Immunol Immunopathol (2002) 0.83
An epitope delivery system for use with recombinant mycobacteria. Infect Immun (1998) 0.83
Detection of in vivo production of tumour necrosis factor-alpha by human thyroid epithelial cells. Immunology (1992) 0.83
UV mutation spectra in cell lines from patients with Cockayne's syndrome and ataxia telangiectasia, using the shuttle vector pZ189. Mutat Res (1991) 0.82