Published in EMBO J on April 23, 2015
RNAseq analysis for the diagnosis of muscular dystrophy. Ann Clin Transl Neurol (2015) 0.90
Stem and Progenitor Cell-Derived Astroglia Therapies for Neurological Diseases. Trends Mol Med (2015) 0.81
Development of stem cell-based therapy for Parkinson's disease. Transl Neurodegener (2015) 0.80
Probing disorders of the nervous system using reprogramming approaches. EMBO J (2015) 0.79
Computational methods for direct cell conversion. Cell Cycle (2016) 0.75
Development of regional specificity of spinal and medullary dorsal horn neurons. World J Biol Chem (2016) 0.75
Replacing reprogramming factors with antibodies selected from combinatorial antibody libraries. Nat Biotechnol (2017) 0.75
Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell (2007) 101.42
Induced pluripotent stem cell lines derived from human somatic cells. Science (2007) 71.50
Direct conversion of fibroblasts to functional neurons by defined factors. Nature (2010) 18.76
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell (2010) 14.18
Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature (2008) 12.21
Direct cell reprogramming is a stochastic process amenable to acceleration. Nature (2009) 8.71
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nat Neurosci (2007) 7.77
A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell (2010) 7.51
Modelling schizophrenia using human induced pluripotent stem cells. Nature (2011) 7.41
The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature (2009) 7.39
Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase. Cell (2012) 7.17
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature (2009) 7.04
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature (2009) 6.85
Induction of human neuronal cells by defined transcription factors. Nature (2011) 6.84
Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature (2011) 6.51
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. Nature (2011) 6.21
Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model. Nat Neurosci (2007) 6.08
MicroRNA-mediated conversion of human fibroblasts to neurons. Nature (2011) 5.59
The promise of induced pluripotent stem cells in research and therapy. Nature (2012) 5.05
Direct conversion of human fibroblasts to dopaminergic neurons. Proc Natl Acad Sci U S A (2011) 4.81
Anatomic demarcation by positional variation in fibroblast gene expression programs. PLoS Genet (2006) 4.75
Conversion of mouse and human fibroblasts into functional spinal motor neurons. Cell Stem Cell (2011) 4.65
Direct reprogramming of mouse fibroblasts to neural progenitors. Proc Natl Acad Sci U S A (2011) 3.93
Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions. Cell Stem Cell (2011) 3.62
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. Proc Natl Acad Sci U S A (2012) 3.52
Glial cells generate neurons: the role of the transcription factor Pax6. Nat Neurosci (2002) 3.37
Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells. Cell Stem Cell (2011) 3.31
Small molecules enable highly efficient neuronal conversion of human fibroblasts. Nat Methods (2012) 2.64
Generation of oligodendroglial cells by direct lineage conversion. Nat Biotechnol (2013) 2.64
Directing astroglia from the cerebral cortex into subtype specific functional neurons. PLoS Biol (2010) 2.60
In vivo reprogramming of astrocytes to neuroblasts in the adult brain. Nat Cell Biol (2013) 2.56
Generation of induced neurons via direct conversion in vivo. Proc Natl Acad Sci U S A (2013) 2.51
Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron (2013) 2.51
Direct lineage conversion of terminally differentiated hepatocytes to functional neurons. Cell Stem Cell (2011) 2.49
Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits. Cell (2013) 2.43
Functional properties of neurons derived from in vitro reprogrammed postnatal astroglia. J Neurosci (2007) 2.27
Functional integration of dopaminergic neurons directly converted from mouse fibroblasts. Cell Stem Cell (2011) 1.95
Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Cell (2013) 1.92
Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells. Cell Stem Cell (2012) 1.76
Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons. Nat Commun (2013) 1.69
The Ink4a/Arf locus is a barrier to direct neuronal transdifferentiation. J Neurosci (2014) 1.48
Generation of induced neuronal cells by the single reprogramming factor ASCL1. Stem Cell Reports (2014) 1.45
Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity. Nat Neurosci (2013) 1.36
Direct reprogramming of human astrocytes into neural stem cells and neurons. Exp Cell Res (2012) 1.26
Remote control of induced dopaminergic neurons in parkinsonian rats. J Clin Invest (2014) 1.23
Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector. PLoS One (2011) 1.21
Nonviral direct conversion of primary mouse embryonic fibroblasts to neuronal cells. Mol Ther Nucleic Acids (2012) 1.20
Generation of human striatal neurons by microRNA-dependent direct conversion of fibroblasts. Neuron (2014) 1.11
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation. Proc Natl Acad Sci U S A (2013) 1.09
Ectopic expression of neurogenin 2 alone is sufficient to induce differentiation of embryonic stem cells into mature neurons. PLoS One (2012) 1.05
Cellular therapy and induced neuronal replacement for Huntington's disease. Neurotherapeutics (2011) 0.97
Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts. Nat Neurosci (2014) 0.96
MicroRNA-based promotion of human neuronal differentiation and subtype specification. PLoS One (2013) 0.95
Cell transplantation and gene therapy in Parkinson's disease. Mt Sinai J Med (2011) 0.91
Selective conversion of fibroblasts into peripheral sensory neurons. Nat Neurosci (2014) 0.89
Effect of NeuroD2 expression on neuronal differentiation in mouse embryonic stem cells. Cell Biol Int (2008) 0.87
Regenerative medicine: transdifferentiation in vivo. Cell Res (2013) 0.86
Reprogramming of postnatal astroglia of the mouse neocortex into functional, synapse-forming neurons. Methods Mol Biol (2012) 0.84