Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity.

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Published in Mol Metab on March 05, 2015

Authors

Rafael Mayoral1, Olivia Osborn2, Joanne McNelis2, Andrew M Johnson2, Da Young Oh2, Cristina Llorente Izquierdo3, Heekyung Chung2, Pingping Li2, Paqui G Traves4, Gautam Bandyopadhyay2, Ariane R Pessentheiner5, Jachelle M Ofrecio2, Joshua R Cook6, Li Qiang6, Domenico Accili6, Jerrold M Olefsky2

Author Affiliations

1: Division of Endocrinology and Metabolism, Department of Medicine, University of California San Diego (UCSD), La Jolla, CA 92093, USA ; Networked Biomedical Research Center, Hepatic and Digestive Diseases (CIBERehd), Monforte de Lemos 3-5, ISC-III, 28029 Madrid, Spain.
2: Division of Endocrinology and Metabolism, Department of Medicine, University of California San Diego (UCSD), La Jolla, CA 92093, USA.
3: Division of Gastroenterology, Department of Medicine, University of California San Diego (UCSD), La Jolla, CA 92093, USA.
4: Molecular Neurobiology Laboratory, The Salk Institute, La Jolla, CA 92037, USA.
5: Institute of Biochemistry, Humboldtstrasse 46/3, 8010 Graz, Austria.
6: Naomi Berrie Diabetes Center, Department of Medicine, Columbia University, New York, NY 10032, USA.

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