Published in Mol Metab on February 13, 2015
A high definition look at the NF-Y regulome reveals genome-wide associations with selected transcription factors. Nucleic Acids Res (2016) 0.78
NF-Y (CBF) regulation in specific cell types and mouse models. Biochim Biophys Acta (2016) 0.75
Transcription factor NF‑YA promotes a malignant phenotype by upregulating fatty acid synthase expression. Mol Med Rep (2016) 0.75
Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner. Mol Metab (2017) 0.75
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science (2004) 19.08
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature (2003) 16.48
Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med (1995) 8.51
A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood. Proc Natl Acad Sci U S A (1999) 7.48
SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis. Cell (1994) 7.10
Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nat Med (1995) 5.45
Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin. Nat Genet (2001) 4.74
The molecular biology of the CCAAT-binding factor NF-Y. Gene (1999) 4.36
Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration. Cell Metab (2008) 4.36
Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease. J Lipid Res (2007) 3.96
Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fos. Cell (1987) 3.89
Tracking adipogenesis during white adipose tissue development, expansion and regeneration. Nat Med (2013) 3.86
The hormonal control of food intake. Cell (2007) 3.61
Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes. Cell (2000) 2.98
Transcriptional control of adipose lipid handling by IRF4. Cell Metab (2011) 2.95
Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy. Nat Med (2005) 2.78
Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones. J Clin Endocrinol Metab (2002) 2.76
Characterization of the adipocyte cellular lineage in vivo. Nat Cell Biol (2013) 2.66
Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance. Proc Natl Acad Sci U S A (2005) 2.60
Leptin signaling, adiposity, and energy balance. Ann N Y Acad Sci (2002) 2.54
Effects of gender, body composition, and menopause on plasma concentrations of leptin. J Clin Endocrinol Metab (1996) 2.40
Genome-wide occupancy of SREBP1 and its partners NFY and SP1 reveals novel functional roles and combinatorial regulation of distinct classes of genes. PLoS Genet (2008) 2.34
Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (1995) 2.17
Transcriptional control of adipogenesis. Annu Rev Nutr (2000) 2.14
Lessons on conditional gene targeting in mouse adipose tissue. Diabetes (2013) 2.04
Transcriptional activation of the mouse obese (ob) gene by CCAAT/enhancer binding protein alpha. Proc Natl Acad Sci U S A (1996) 1.92
Identification and characterization of a promoter cassette conferring adipocyte-specific gene expression. Endocrinology (2010) 1.71
The B subunit of the CCAAT box binding transcription factor complex (CBF/NF-Y) is essential for early mouse development and cell proliferation. Cancer Res (2003) 1.63
Transplantation of adipose tissue and stem cells: role in metabolism and disease. Nat Rev Endocrinol (2010) 1.56
Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes. Proc Natl Acad Sci U S A (1997) 1.55
NF-Ya activates multiple hematopoietic stem cell (HSC) regulatory genes and promotes HSC self-renewal. Proc Natl Acad Sci U S A (2005) 1.44
Protocol for effective differentiation of 3T3-L1 cells to adipocytes. Anal Biochem (2012) 1.37
Analysis of gene networks in white adipose tissue development reveals a role for ETS2 in adipogenesis. Development (2011) 1.36
Down-regulation of cyclin B1 gene transcription in terminally differentiated skeletal muscle cells is associated with loss of functional CCAAT-binding NF-Y complex. Oncogene (1999) 1.35
Fatty acid binding protein 4 expression marks a population of adipocyte progenitors in white and brown adipose tissues. FASEB J (2012) 1.34
Sequence-specific transcription factor NF-Y displays histone-like DNA binding and H2B-like ubiquitination. Cell (2013) 1.33
Lipin proteins and metabolic homeostasis. J Lipid Res (2008) 1.32
A balance between NF-Y and p53 governs the pro- and anti-apoptotic transcriptional response. Nucleic Acids Res (2008) 1.32
A chromatin-modifying function of JNK during stem cell differentiation. Nat Genet (2011) 1.31
Hyperleptinemia is more closely associated with adipose cell hypertrophy than with adipose tissue hyperplasia. Int J Obes Relat Metab Disord (2000) 1.19
Requirement for down-regulation of the CCAAT-binding activity of the NF-Y transcription factor during skeletal muscle differentiation. Mol Biol Cell (2003) 1.19
NF-Y coassociates with FOS at promoters, enhancers, repetitive elements, and inactive chromatin regions, and is stereo-positioned with growth-controlling transcription factors. Genome Res (2013) 1.15
Fat cell turnover in humans. Biochem Biophys Res Commun (2010) 1.15
CCAAT/enhancer binding protein and nuclear factor-Y regulate adiponectin gene expression in adipose tissue. Diabetes (2004) 1.14
Functional STAT 1 and 3 signaling by the leptin receptor (OB-R); reduced expression of the rat fatty leptin receptor in transfected cells. Endocrinology (1996) 1.13
Cellular program controlling the recovery of adipose tissue mass: An in vivo imaging approach. Proc Natl Acad Sci U S A (2008) 1.09
NF-Y dependent epigenetic modifications discriminate between proliferating and postmitotic tissue. PLoS One (2008) 1.05
NF-Y is necessary for hematopoietic stem cell proliferation and survival. Blood (2011) 1.01
Histone-fold domain protein NF-Y promotes chromatin accessibility for cell type-specific master transcription factors. Mol Cell (2014) 0.99
FOSL2 promotes leptin gene expression in human and mouse adipocytes. J Clin Invest (2012) 0.97
NF-Y recruits both transcription activator and repressor to modulate tissue- and developmental stage-specific expression of human γ-globin gene. PLoS One (2012) 0.90
Dyslipemia in familial partial lipodystrophy caused by an R482W mutation in the LMNA gene. J Clin Endocrinol Metab (2001) 0.89
The short isoform of NF-YA belongs to the embryonic stem cell transcription factor circuitry. Stem Cells (2012) 0.88
Acquired and inherited lipodystrophies. N Engl J Med (2004) 0.88
NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization. Nat Commun (2014) 0.88
The role of LMNA in adipose: a novel mouse model of lipodystrophy based on the Dunnigan-type familial partial lipodystrophy mutation. J Lipid Res (2009) 0.87
Molecular imaging of nuclear factor-Y transcriptional activity maps proliferation sites in live animals. Mol Biol Cell (2012) 0.86
A mutation in the c-fos gene associated with congenital generalized lipodystrophy. Orphanet J Rare Dis (2013) 0.86
Understanding leptin-dependent regulation of skeletal homeostasis. Biochimie (2012) 0.86
Transcriptional activation of PRMT5 by NF-Y is required for cell growth and negatively regulated by the PKC/c-Fos signaling in prostate cancer cells. Biochim Biophys Acta (2014) 0.84
Nuclear transcription factor Y and its roles in cellular processes related to human disease. Am J Cancer Res (2013) 0.80
Activation of arcuate nucleus neurons by systemic administration of leptin and growth hormone-releasing peptide-6 in normal and fasted rats. Neuroendocrinology (1999) 0.80
Appearance of leptin in wound fluid as a response to injury. Wound Repair Regen (2002) 0.80
Analysis of a 762-bp proximal leptin promoter to drive and control regulation of transgene expression of growth hormone receptor in mice. Biochem Biophys Res Commun (1999) 0.79
Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy. Hum Mol Genet (2014) 0.78
A rapid, quantitative functional assay for measuring leptin. Mol Cell Endocrinol (1998) 0.77
Serum leptin activity in obese and lean patients. Regul Pept (2003) 0.76