CrisprGE: a central hub of CRISPR/Cas-based genome editing.

PubWeight™: 0.84‹?›

🔗 View Article (PMC 4483309)

Published in Database (Oxford) on June 27, 2015

Authors

Karambir Kaur1, Himani Tandon1, Amit Kumar Gupta1, Manoj Kumar2

Author Affiliations

1: Bioinformatics Centre, Institute of Microbial Technology, Council of Scientific and Industrial Research, Sector 39A, Chandigarh 160036, India.
2: Bioinformatics Centre, Institute of Microbial Technology, Council of Scientific and Industrial Research, Sector 39A, Chandigarh 160036, India manojk@imtech.res.in.

Articles cited by this

Multiplex genome engineering using CRISPR/Cas systems. Science (2013) 55.53

RNA-guided human genome engineering via Cas9. Science (2013) 48.29

A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science (2012) 48.17

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell (2013) 24.00

Breaking the code of DNA binding specificity of TAL-type III effectors. Science (2009) 22.33

Efficient genome editing in zebrafish using a CRISPR-Cas system. Nat Biotechnol (2013) 21.32

CRISPR/Cas, the immune system of bacteria and archaea. Science (2010) 18.72

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain. Proc Natl Acad Sci U S A (1996) 12.25

A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes. PLoS Comput Biol (2005) 11.82

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol (2013) 11.58

Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases. Nat Biotechnol (2008) 10.29

Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin. Microbiology (2005) 10.20

CRISPR-Cas systems for editing, regulating and targeting genomes. Nat Biotechnol (2014) 9.18

Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases. Genetics (2002) 9.09

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases. Nat Biotechnol (2007) 8.88

Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV. N Engl J Med (2014) 7.64

Cas9 as a versatile tool for engineering biology. Nat Methods (2013) 6.87

TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain. Nucleic Acids Res (2010) 6.65

Heritable genome editing in C. elegans via a CRISPR-Cas9 system. Nat Methods (2013) 5.93

Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product. J Bacteriol (1987) 5.28

Genome engineering with zinc-finger nucleases. Genetics (2011) 4.66

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity. Nucleic Acids Res (2013) 4.11

Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9. Nat Biotechnol (2013) 3.84

CRISPR-mediated direct mutation of cancer genes in the mouse liver. Nature (2014) 3.28

Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila. Proc Natl Acad Sci U S A (2014) 2.97

Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA. Science (2014) 2.93

Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA. Sci Rep (2013) 2.41

RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection. Proc Natl Acad Sci U S A (2014) 2.32

Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9. Proc Natl Acad Sci U S A (2013) 2.13

Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platform. Nat Commun (2014) 1.88

Gene-editing nucleases. Nat Methods (2012) 1.66

Application of the CRISPR-Cas system for efficient genome engineering in plants. Mol Plant (2013) 1.63

Seamless gene correction of β-thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and piggyBac. Genome Res (2014) 1.63

Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice. Nucleic Acids Res (2014) 1.58

CRISPR/Cas9 nuclease-mediated gene knock-in in bovine-induced pluripotent cells. Stem Cells Dev (2014) 1.47

The CRISPR/Cas9 System Facilitates Clearance of the Intrahepatic HBV Templates In Vivo. Mol Ther Nucleic Acids (2014) 1.46

Conditional knockouts generated by engineered CRISPR-Cas9 endonuclease reveal the roles of coronin in C. elegans neural development. Dev Cell (2014) 1.29

A PCR based protocol for detecting indel mutations induced by TALENs and CRISPR/Cas9 in zebrafish. PLoS One (2014) 1.23

Efficient in vivo deletion of a large imprinted lncRNA by CRISPR/Cas9. RNA Biol (2014) 1.16

Heritable multiplex genetic engineering in rats using CRISPR/Cas9. PLoS One (2014) 1.14

Precise gene deletion and replacement using the CRISPR/Cas9 system in human cells. Biotechniques (2014) 1.07

Efficient, complete deletion of synaptic proteins using CRISPR. Neuron (2014) 1.06

Genome engineering of mammalian haploid embryonic stem cells using the Cas9/RNA system. PeerJ (2013) 1.00

CRISPR-Cas: an efficient tool for genome engineering of virulent bacteriophages. Nucleic Acids Res (2014) 0.96

One-step generation of phenotype-expressing triple-knockout mice with heritable mutated alleles by the CRISPR/Cas9 system. J Reprod Dev (2014) 0.92

CRISPR/Cas9-mediated gene knockout in the ascidian Ciona intestinalis. Dev Growth Differ (2014) 0.91

Tissue-specific genome editing in Ciona embryos by CRISPR/Cas9. Development (2014) 0.90

EENdb: a database and knowledge base of ZFNs and TALENs for endonuclease engineering. Nucleic Acids Res (2012) 0.90

Disruption of HPV16-E7 by CRISPR/Cas system induces apoptosis and growth inhibition in HPV16 positive human cervical cancer cells. Biomed Res Int (2014) 0.87

A CRISPR-based approach for proteomic analysis of a single genomic locus. Epigenetics (2014) 0.81