Published in Sci Rep on November 04, 2015
Role of Aromatic Amino Acids in Lipopolysaccharide and Membrane Interactions of Antimicrobial Peptides for Use in Plant Disease Control. J Biol Chem (2016) 0.78
Mode of Action of a Designed Antimicrobial Peptide: High Potency against Cryptococcus neoformans. Biophys J (2016) 0.75
Plant flavones enhance antimicrobial activity of respiratory epithelial cell secretions against Pseudomonas aeruginosa. PLoS One (2017) 0.75
Phosphorus assay in column chromatography. J Biol Chem (1959) 60.56
Antimicrobial peptides of multicellular organisms. Nature (2002) 23.50
Use of helical wheels to represent the structures of proteins and to identify segments with helical potential. Biophys J (1967) 8.10
Mechanisms of antimicrobial peptide action and resistance. Pharmacol Rev (2003) 6.57
APD2: the updated antimicrobial peptide database and its application in peptide design. Nucleic Acids Res (2008) 4.23
Statistical analysis of amino acid patterns in transmembrane helices: the GxxxG motif occurs frequently and in association with beta-branched residues at neighboring positions. J Mol Biol (2000) 3.95
Mechanism of interaction of different classes of cationic antimicrobial peptides with planar bilayers and with the cytoplasmic membrane of Escherichia coli. Biochemistry (1999) 3.88
Action of antimicrobial peptides: two-state model. Biochemistry (2000) 3.49
Compound helical configurations of polypeptide chains: structure of proteins of the alpha-keratin type. Nature (1953) 2.36
Rational design of alpha-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index. J Biol Chem (2005) 2.28
Arming the enemy: the evolution of resistance to self-proteins. Microbiology (2003) 1.95
Amphipathic alpha helical antimicrobial peptides. Eur J Biochem (2001) 1.90
Peptide-membrane interactions and mechanisms of membrane destruction by amphipathic alpha-helical antimicrobial peptides. Biochim Biophys Acta (2006) 1.62
Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides. Biopolymers (2008) 1.51
The role of position a in determining the stability and oligomerization state of alpha-helical coiled coils: 20 amino acid stability coefficients in the hydrophobic core of proteins. Protein Sci (1999) 1.45
Role of lipids in the interaction of antimicrobial peptides with membranes. Prog Lipid Res (2012) 1.39
The role of interhelical ionic interactions in controlling protein folding and stability. De novo designed synthetic two-stranded alpha-helical coiled-coils. J Mol Biol (1994) 1.38
Alpha-helical antimicrobial peptides--using a sequence template to guide structure-activity relationship studies. Biochim Biophys Acta (2006) 1.37
Overview on the recent study of antimicrobial peptides: origins, functions, relative mechanisms and application. Peptides (2012) 1.34
Design of synthetic antimicrobial peptides based on sequence analogy and amphipathicity. Eur J Biochem (1997) 1.28
Length effects in antimicrobial peptides of the (RW)n series. Antimicrob Agents Chemother (2006) 1.16
Roles of hydrophobicity and charge distribution of cationic antimicrobial peptides in peptide-membrane interactions. J Biol Chem (2012) 1.14
Multifunctional host defense peptides: antimicrobial peptides, the small yet big players in innate and adaptive immunity. FEBS J (2009) 1.08
Lactoferricin B inhibits bacterial macromolecular synthesis in Escherichia coli and Bacillus subtilis. FEMS Microbiol Lett (2004) 1.06
Antimicrobial and membrane disrupting activities of a peptide derived from the human cathelicidin antimicrobial peptide LL37. Biophys J (2010) 1.06
Controlled alteration of the shape and conformational stability of alpha-helical cell-lytic peptides: effect on mode of action and cell specificity. Biochem J (2005) 1.05
Tethering antimicrobial peptides: current status and potential challenges. Biotechnol Adv (2010) 1.01
Amphiphilic alpha-helical antimicrobial peptides and their structure/function relationships. Protein Pept Lett (2005) 1.01
Synthetic cationic amphiphilic α-helical peptides as antimicrobial agents. Biomaterials (2010) 0.99
Antimicrobial properties and membrane-active mechanism of a potential α-helical antimicrobial derived from cathelicidin PMAP-36. PLoS One (2014) 0.97
Inhibitory effects and mechanisms of physiological conditions on the activity of enantiomeric forms of an α-helical antibacterial peptide against bacteria. Peptides (2011) 0.94
De novo generation of short antimicrobial peptides with enhanced stability and cell specificity. J Antimicrob Chemother (2013) 0.94
Antimicrobial potency and selectivity of simplified symmetric-end peptides. Biomaterials (2014) 0.93
Computational design of highly selective antimicrobial peptides. J Chem Inf Model (2009) 0.93
Tuning the biological properties of amphipathic alpha-helical antimicrobial peptides: rational use of minimal amino acid substitutions. Peptides (2005) 0.93
Design of imperfectly amphipathic α-helical antimicrobial peptides with enhanced cell selectivity. Acta Biomater (2013) 0.93
Structural contributions to the intracellular targeting strategies of antimicrobial peptides. Biochim Biophys Acta (2010) 0.92
Molecular mechanisms of antibacterial and antitumor actions of designed surfactant-like peptides. Biomaterials (2011) 0.90
Effect of repetitive lysine-tryptophan motifs on the bactericidal activity of antimicrobial peptides. Amino Acids (2012) 0.88
Fluorinated interfaces drive self-association of transmembrane alpha helices in lipid bilayers. Angew Chem Int Ed Engl (2006) 0.88
Anti-mycobacterial activities of synthetic cationic α-helical peptides and their synergism with rifampicin. Biomaterials (2013) 0.86
Hydrophobic moments of tertiary protein structures. Proteins (2003) 0.85
Strand length-dependent antimicrobial activity and membrane-active mechanism of arginine- and valine-rich β-hairpin-like antimicrobial peptides. Antimicrob Agents Chemother (2012) 0.84
Flexibility is a mechanical determinant of antimicrobial activity for amphipathic cationic α-helical antimicrobial peptides. Biochim Biophys Acta (2013) 0.83
Design of hybrid β-hairpin peptides with enhanced cell specificity and potent anti-inflammatory activity. Biomaterials (2012) 0.83
In vitro activities of tachyplesin III against Pseudomonas aeruginosa. Peptides (2007) 0.80
Design of perfectly symmetric Trp-rich peptides with potent and broad-spectrum antimicrobial activities. Int J Antimicrob Agents (2006) 0.80
Characterization of antimicrobial activity and mechanisms of low amphipathic peptides with different α-helical propensity. Acta Biomater (2015) 0.79
Cell specificity, anti-inflammatory activity, and plausible bactericidal mechanism of designed Trp-rich model antimicrobial peptides. Biochim Biophys Acta (2009) 0.79
Bactericidal efficiency and modes of action of the novel antimicrobial peptide T9W against Pseudomonas aeruginosa. Antimicrob Agents Chemother (2015) 0.78
Rapid method for detection of minimal bactericidal concentration of antibiotics. J Microbiol Methods (2009) 0.78
Biochemical property and membrane-peptide interactions of de novo antimicrobial peptides designed by helix-forming units. Amino Acids (2012) 0.78
Engineering antimicrobial peptides with improved antimicrobial and hemolytic activities. J Chem Inf Model (2013) 0.78
Divalent cations modulate membrane binding and pore formation of a potent antibiotic peptide analog of alamethicin. Cell Calcium (2012) 0.77
Dicynthaurin (ala) monomer interaction with phospholipid bilayers studied by fluorescence leakage and isothermal titration calorimetry. J Phys Chem B (2007) 0.77
Structure-activity relationship of the antimicrobial peptide gomesin: the role of peptide hydrophobicity in its interaction with model membranes. Langmuir (2014) 0.77
Design of short membrane selective antimicrobial peptides containing tryptophan and arginine residues for improved activity, salt-resistance, and biocompatibility. Biotechnol Bioeng (2013) 0.77
Structure-function relationship of Val/Arg-rich peptides: effects of net charge and pro on activity. Chem Biol Drug Des (2014) 0.77
The helical propensity of KLA amphipathic peptides enhances their binding to gel-state lipid membranes. Biophys Chem (2013) 0.76
Interaction mode of a symmetric Trp-rich undeca peptide PST11-RK with lipid bilayers. FEBS Lett (2006) 0.76