CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity.

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Published in Cell on November 19, 2015

Authors

Chao Wang1, Nir Yosef2, Jellert Gaublomme3, Chuan Wu1, Youjin Lee1, Clary B Clish4, Jim Kaminski5, Sheng Xiao1, Gerd Meyer Zu Horste1, Mathias Pawlak1, Yasuhiro Kishi6, Nicole Joller1, Katarzyna Karwacz1, Chen Zhu1, Maria Ordovas-Montanes1, Asaf Madi7, Ivo Wortman4, Toru Miyazaki8, Raymond A Sobel9, Hongkun Park3, Aviv Regev10, Vijay K Kuchroo11

Author Affiliations

1: Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
2: Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA; Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA 94720, USA; Center for Computational Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
3: Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA; Department of Chemistry and Chemical Biology and Department of Physics, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA.
4: Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA.
5: Center for Computational Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
6: Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA; Mitsubishi Tanabe Pharma Corporation, Kamoshida-cho 1000, Yokohama, 225-0002, Japan.
7: Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA.
8: Laboratory of Molecular Biomedicine for Pathogenesis, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.
9: Palo Alto Veteran's Administration Health Care System and Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
10: Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA; Howard Hughes Medical Institute and David H. Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 20140, USA. Electronic address: aregev@broadinstitute.org.
11: Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA. Electronic address: vkuchroo@evergrande.hms.harvard.edu.

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