B Cells, Antibodies, and More.

Belatacept Does Not Inhibit Follicular T Cell-Dependent B-Cell Differentiation in Kidney Transplantation. Front Immunol (2017) 1.39

A Randomized, Controlled Trial of Rituximab in IgA Nephropathy with Proteinuria and Renal Dysfunction. J Am Soc Nephrol (2016) 0.81

Heterogeneity of B Cell Functions in Stroke-Related Risk, Prevention, Injury, and Repair. Neurotherapeutics (2016) 0.75

Antigen-specific immunotherapies in rheumatic diseases. Nat Rev Rheumatol (2017) 0.75

High Levels of (Un)Switched Memory B Cells Are Associated With Better Outcome in Patients With Advanced Atherosclerotic Disease. J Am Heart Assoc (2017) 0.75

Continuing the paradigm shift in the treatment of idiopathic membranous nephropathy. Nat Rev Nephrol (2017) 0.75

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell (2000) 20.83

Predominant autoantibody production by early human B cell precursors. Science (2003) 13.14

M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. N Engl J Med (2009) 11.81

Innate IL-17-producing cells: the sentinels of the immune system. Nat Rev Immunol (2010) 6.88

Complement-binding anti-HLA antibodies and kidney-allograft survival. N Engl J Med (2013) 6.31

Germinal centers. Annu Rev Immunol (2012) 6.26

Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression. J Clin Invest (2008) 5.85

Efficacy of remission-induction regimens for ANCA-associated vasculitis. N Engl J Med (2013) 5.67

Hyperacute rejection of kidney allografts, associated with pre-existing humoral antibodies against donor cells. Lancet (1966) 5.54

Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice. J Clin Invest (2002) 5.42

CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients. Immunity (2010) 5.13

Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs. Annu Rev Immunol (2005) 5.10

Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment. Annu Rev Immunol (1999) 4.97

Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection. N Engl J Med (2005) 4.84

Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: the Lupus Nephritis Assessment with Rituximab study. Arthritis Rheum (2012) 4.80

Reciprocal regulation of polarized cytokine production by effector B and T cells. Nat Immunol (2000) 4.73

BCMA is essential for the survival of long-lived bone marrow plasma cells. J Exp Med (2004) 4.41

Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling. N Engl J Med (2003) 4.35

Intravenous immunoglobulin therapy: how does IgG modulate the immune system? Nat Rev Immunol (2013) 4.33

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells. Blood (2010) 4.28

The double life of a B-1 cell: self-reactivity selects for protective effector functions. Nat Rev Immunol (2010) 4.26

Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5. Nat Immunol (2004) 4.22

Defective B cell tolerance checkpoints in systemic lupus erythematosus. J Exp Med (2005) 4.16

Class-switch recombination: interplay of transcription, DNA deamination and DNA repair. Nat Rev Immunol (2004) 4.04

Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+ CD27+ CD43+ CD70-. J Exp Med (2011) 3.89

Rituximab in idiopathic membranous nephropathy. J Am Soc Nephrol (2012) 3.79

A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J Exp Med (1999) 3.74

Regulatory B cells as inhibitors of immune responses and inflammation. Immunol Rev (2008) 3.67

Human immunoglobulin M memory B cells controlling Streptococcus pneumoniae infections are generated in the spleen. J Exp Med (2003) 3.64

Different B cell populations mediate early and late memory during an endogenous immune response. Science (2011) 3.63

Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest (2010) 3.59

Effector and regulatory B cells: modulators of CD4+ T cell immunity. Nat Rev Immunol (2010) 3.56

Identification of a receptor required for the anti-inflammatory activity of IVIG. Proc Natl Acad Sci U S A (2008) 3.55

Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans. J Clin Invest (2010) 3.41

Multiple layers of B cell memory with different effector functions. Nat Immunol (2009) 3.33

Pax5: the guardian of B cell identity and function. Nat Immunol (2007) 3.15

Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus. J Immunol (2000) 3.05

BAFF selectively enhances the survival of plasmablasts generated from human memory B cells. J Clin Invest (2003) 2.87

Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone. Immunity (2011) 2.81

The follicular versus marginal zone B lymphocyte cell fate decision. Nat Rev Immunol (2009) 2.80

Rituximab-induced depletion of anti-PLA2R autoantibodies predicts response in membranous nephropathy. J Am Soc Nephrol (2011) 2.72

Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo. J Immunol (2000) 2.67

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases. Nature (2014) 2.58

B-cell-depleting induction therapy and acute cellular rejection. N Engl J Med (2009) 2.56

Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus. J Clin Invest (2005) 2.55

Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes. Nat Rev Immunol (2013) 2.49

Cytokine-producing effector B cells regulate type 2 immunity to H. polygyrus. Immunity (2009) 2.45

FcgammaRIIB in autoimmunity and infection: evolutionary and therapeutic implications. Nat Rev Immunol (2010) 2.44

Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice. J Clin Invest (2011) 2.40

Primary T cell expansion and differentiation in vivo requires antigen presentation by B cells. J Immunol (2006) 2.40

Outcome of ANCA-associated renal vasculitis: a 5-year retrospective study. Am J Kidney Dis (2003) 2.40

The 'short' history of regulatory B cells. Trends Immunol (2007) 2.38

Splenic T zone development is B cell dependent. J Exp Med (2001) 2.35

B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin alpha-dependent fashion. J Exp Med (1998) 2.32

Banff 2011 Meeting report: new concepts in antibody-mediated rejection. Am J Transplant (2012) 2.28

Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus. Arthritis Rheum (2004) 2.23

Normal B cell homeostasis requires B cell activation factor production by radiation-resistant cells. J Exp Med (2003) 2.20

Germinal center selection and the development of memory B and plasma cells. Immunol Rev (2012) 2.17

TLR-mediated stimulation of APC: Distinct cytokine responses of B cells and dendritic cells. Eur J Immunol (2007) 2.15

Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell (1996) 2.09

B-cell anergy: from transgenic models to naturally occurring anergic B cells? Nat Rev Immunol (2007) 2.08

Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy. Arthritis Rheum (2007) 2.03

B lymphocytes regulate dendritic cell (DC) function in vivo: increased interleukin 12 production by DCs from B cell-deficient mice results in T helper cell type 1 deviation. J Exp Med (2000) 2.02

ABO-incompatible heart transplantation in infants. N Engl J Med (2001) 2.01

Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: delineation by expression of CD27, IgD, and CD95. Arthritis Rheum (2008) 2.00

B-cell tolerance checkpoints in health and autoimmunity. Curr Opin Immunol (2008) 1.99

Blood group isoantibody stimulation in man by feeding blood group-active bacteria. J Clin Invest (1969) 1.97

A randomized controlled trial of rituximab for the treatment of severe cryoglobulinemic vasculitis. Arthritis Rheum (2012) 1.96

Germinal center B and follicular helper T cells: siblings, cousins or just good friends? Nat Immunol (2011) 1.95

IgG subclasses and allotypes: from structure to effector functions. Front Immunol (2014) 1.95

Donor-specific B-cell tolerance after ABO-incompatible infant heart transplantation. Nat Med (2004) 1.92

Class-switched memory B cells remodel BCRs within secondary germinal centers. Nat Immunol (2015) 1.90

The generation of antibody-secreting plasma cells. Nat Rev Immunol (2015) 1.87

B cell biomarkers of rituximab responses in systemic lupus erythematosus. Arthritis Rheum (2011) 1.86

B cells are required for generation of protective effector and memory CD4 cells in response to Pneumocystis lung infection. J Immunol (2006) 1.86

Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow. J Exp Med (2005) 1.86

Effects of belimumab, a B lymphocyte stimulator-specific inhibitor, on disease activity across multiple organ domains in patients with systemic lupus erythematosus: combined results from two phase III trials. Ann Rheum Dis (2012) 1.85

Selective dysregulation of the FcgammaIIB receptor on memory B cells in SLE. J Exp Med (2006) 1.81

A small CD11b(+) human B1 cell subpopulation stimulates T cells and is expanded in lupus. J Exp Med (2011) 1.78

IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/Ipr mice. J Immunol (1997) 1.78

Marginal zone, but not follicular B cells, are potent activators of naive CD4 T cells. J Immunol (2004) 1.76

Signaling via the MyD88 adaptor protein in B cells suppresses protective immunity during Salmonella typhimurium infection. Immunity (2010) 1.75

B cell deficiency confers protection from renal ischemia reperfusion injury. J Immunol (2003) 1.73

Management of noninfectious mixed cryoglobulinemia vasculitis: data from 242 cases included in the CryoVas survey. Blood (2012) 1.73

Somatic hypermutation of immunoglobulin genes: merging mechanisms for genetic diversity. Cell (2002) 1.73

Chronic humoral rejection: identification of antibody-mediated chronic renal allograft rejection by C4d deposits in peritubular capillaries. J Am Soc Nephrol (2001) 1.72

The impact of donor-specific anti-HLA antibodies on late kidney allograft failure. Nat Rev Nephrol (2012) 1.71

XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development. J Exp Med (2009) 1.71

IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4. J Immunol (2008) 1.68

Belimumab in the treatment of systemic lupus erythematosus: high disease activity predictors of response. Ann Rheum Dis (2012) 1.67

CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance. J Exp Med (2007) 1.61

BAFF and BAFF-R levels are associated with risk of long-term kidney graft dysfunction and development of donor-specific antibodies. Am J Transplant (2012) 1.60

Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity. J Clin Invest (2013) 1.60

A specific role for B cells in the generation of CD8 T cell memory by recombinant Listeria monocytogenes. J Immunol (2003) 1.59

Novel function of B cell-activating factor in the induction of IL-10-producing regulatory B cells. J Immunol (2010) 1.57

B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events. J Clin Invest (1996) 1.56

Comparative transcriptional and phenotypic peripheral blood analysis of kidney recipients under cyclosporin A or sirolimus monotherapy. Am J Transplant (2010) 1.54

In situ B cell-mediated immune responses and tubulointerstitial inflammation in human lupus nephritis. J Immunol (2010) 1.54

Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4. Immunity (2013) 1.52

In situ production of TNF-alpha, IL-1 beta and IL-2R in ANCA-positive glomerulonephritis. Kidney Int (1993) 1.49