Published in J Immunol on March 05, 2010
The double life of a B-1 cell: self-reactivity selects for protective effector functions. Nat Rev Immunol (2010) 4.26
Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice. J Clin Invest (2011) 2.40
B cells and antibodies in multiple sclerosis pathogenesis and therapy. Nat Rev Neurol (2012) 1.80
Clinical targeting of the TNF and TNFR superfamilies. Nat Rev Drug Discov (2013) 1.53
Regulatory B cells in autoimmune diseases. Cell Mol Immunol (2013) 1.36
Regulatory functions of innate-like B cells. Cell Mol Immunol (2013) 1.10
Identification of IFN-γ-producing innate B cells. Cell Res (2013) 1.10
Multiple mechanisms of immune suppression by B lymphocytes. Mol Med (2012) 1.08
Targeting BAFF in autoimmunity. Curr Opin Immunol (2010) 1.08
B cells in MS and NMO: pathogenesis and therapy. Semin Immunopathol (2014) 1.01
Revisiting the B-cell compartment in mouse and humans: more than one B-cell subset exists in the marginal zone and beyond. BMC Immunol (2012) 1.01
T follicular helper cells mediate expansion of regulatory B cells via IL-21 in Lupus-prone MRL/lpr mice. PLoS One (2013) 1.00
A case for regulatory B cells in controlling the severity of autoimmune-mediated inflammation in experimental autoimmune encephalomyelitis and multiple sclerosis. J Neuroimmunol (2010) 0.99
Oestrogen-mediated protection of experimental autoimmune encephalomyelitis in the absence of Foxp3+ regulatory T cells implicates compensatory pathways including regulatory B cells. Immunology (2010) 0.95
BAFF inhibition: a new class of drugs for the treatment of autoimmunity. Exp Cell Res (2011) 0.91
Unraveling effector functions of B cells during infection: the hidden world beyond antibody production. Infect Disord Drug Targets (2012) 0.89
The dual effects of B cell depletion on antigen-specific T cells in BDC2.5NOD mice. J Immunol (2012) 0.89
n-3 PUFAs enhance the frequency of murine B-cell subsets and restore the impairment of antibody production to a T-independent antigen in obesity. J Lipid Res (2013) 0.89
B1 cells promote pancreas infiltration by autoreactive T cells. J Immunol (2010) 0.89
Human invariant NKT cell subsets differentially promote differentiation, antibody production, and T cell stimulation by B cells in vitro. J Immunol (2013) 0.89
Janus-like effects of type I interferon in autoimmune diseases. Immunol Rev (2012) 0.86
CD43-, but not CD43+, IL-10-producing CD1dhiCD5+ B cells suppress type 1 immune responses during Chlamydia muridarum genital tract infection. Mucosal Immunol (2014) 0.85
B Cells, Antibodies, and More. Clin J Am Soc Nephrol (2015) 0.85
Dendritic cell status modulates the outcome of HIV-related B cell disease progression. PLoS Pathog (2011) 0.85
Treatment with IL-10 producing B cells in combination with E2 ameliorates EAE severity and decreases CNS inflammation in B cell-deficient mice. Metab Brain Dis (2015) 0.85
Influence of dendritic cells on B-cell responses during HIV infection. Clin Dev Immunol (2012) 0.84
The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells. Leukemia (2015) 0.84
B Cells and Autoantibodies in Multiple Sclerosis. Int J Mol Sci (2015) 0.83
Understanding the role of B cells in atherosclerosis: potential clinical implications. Expert Rev Clin Immunol (2013) 0.82
Activated peritoneal cavity B-1a cells possess regulatory B cell properties. PLoS One (2014) 0.82
B Cells Are Multifunctional Players in Multiple Sclerosis Pathogenesis: Insights from Therapeutic Interventions. Front Immunol (2015) 0.81
Reprogramming of B cells into regulatory cells with engineered fusokines. Infect Disord Drug Targets (2012) 0.81
CD1d(hi)CD5+ B cells expanded by GM-CSF in vivo suppress experimental autoimmune myasthenia gravis. J Immunol (2014) 0.81
A potential role for B cells in suppressed immune responses in cord blood transplant recipients. Bone Marrow Transplant (2012) 0.81
Role of B cells in tolerance induction. Curr Opin Organ Transplant (2015) 0.81
Aberrant frequency of IL-10-producing B cells and its association with Treg/Th17 in adult primary immune thrombocytopenia patients. Biomed Res Int (2014) 0.81
The dual nature of interleukin-10 in pemphigus vulgaris. Cytokine (2014) 0.81
Retroviral and lentiviral vectors for the induction of immunological tolerance. Scientifica (Cairo) (2012) 0.80
Spleen supports a pool of innate-like B cells in white adipose tissue that protects against obesity-associated insulin resistance. Proc Natl Acad Sci U S A (2014) 0.80
Exacerbated experimental arthritis in Wiskott-Aldrich syndrome protein deficiency: modulatory role of regulatory B cells. Eur J Immunol (2014) 0.80
Regulatory B cells are inversely associated with disease activity in rheumatoid arthritis. Yonsei Med J (2014) 0.80
Inducible IL10(+) suppressor B cells inhibit CNS inflammation and T helper 17 polarization. Mol Ther (2012) 0.79
Autocrine stimulation of IL-10 is critical to the enrichment of IL-10-producing CD40(hi)CD5(+) regulatory B cells in vitro and in vivo. BMB Rep (2015) 0.79
B cells with regulatory properties in transplantation tolerance. World J Transplant (2015) 0.78
Tumor-derived autophagosomes (DRibbles) induce B cell activation in a TLR2-MyD88 dependent manner. PLoS One (2013) 0.78
Autoregulatory function of interleukin-10-producing pre-naïve B cells is defective in systemic lupus erythematosus. Arthritis Res Ther (2015) 0.78
Relationship between circulating BAFF serum levels with proliferating markers in patients with multiple myeloma. Biomed Res Int (2013) 0.78
No evidence that soluble TACI induces signalling via membrane-expressed BAFF and APRIL in myeloid cells. PLoS One (2013) 0.77
The Expansion of CD25 high IL-10 high FoxP3 high B Regulatory Cells Is in Association with SLE Disease Activity. J Immunol Res (2015) 0.77
B-cell-mediated strategies to fight chronic allograft rejection. Front Immunol (2013) 0.77
Meningeal Infiltration of the Spinal Cord by Non-Classically Activated B Cells is Associated with Chronic Disease Course in a Spontaneous B Cell-Dependent Model of CNS Autoimmune Disease. Front Immunol (2015) 0.76
Interferon-β therapy specifically reduces pathogenic memory B cells in multiple sclerosis patients by inducing a FAS-mediated apoptosis. Immunol Cell Biol (2016) 0.76
Serum elevation of B lymphocyte stimulator does not increase regulatory B cells in glioblastoma patients undergoing immunotherapy. Cancer Immunol Immunother (2016) 0.75
Angiotensin II synergizes with BAFF to promote atheroprotective regulatory B cells. Sci Rep (2017) 0.75
Biomarkers in kidney transplantation: From bench to bedside. World J Nephrol (2015) 0.75
NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells. Nat Commun (2016) 0.75
Human regulatory B cells in health and disease: therapeutic potential. J Clin Invest (2017) 0.75
Monoclonal antibodies in the treatment of multiple sclerosis: emergence of B-cell-targeted therapies. Br J Pharmacol (2017) 0.75
Subversion of the B-cell compartment during parasitic, bacterial, and viral infections. BMC Immunol (2015) 0.75
Significant decrease in peripheral regulatory B cells is an immunopathogenic feature of dermatomyositis. Sci Rep (2016) 0.75
The Role of BAFF System Molecules in Host Response to Pathogens. Clin Microbiol Rev (2017) 0.75
Schistosome egg antigens, including the glycoprotein IPSE/alpha-1, trigger the development of regulatory B cells. PLoS Pathog (2017) 0.75
Identification and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology (2007) 5.75
Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma. Cancer Cell (2011) 4.54
Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. Nat Rev Neurol (2013) 4.16
The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ. Nat Immunol (2011) 3.77
MicroRNA-146a feedback inhibits RIG-I-dependent Type I IFN production in macrophages by targeting TRAF6, IRAK1, and IRAK2. J Immunol (2009) 3.72
Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1. J Immunol (2009) 3.27
Splenic stroma drives mature dendritic cells to differentiate into regulatory dendritic cells. Nat Immunol (2004) 3.25
Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology. Am J Pathol (2002) 3.23
Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk. Nat Immunol (2011) 3.12
Comparative analysis of twelve genomes of three novel group 2c and group 2d coronaviruses reveals unique group and subgroup features. J Virol (2006) 3.07
The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway. Nat Immunol (2010) 2.95
Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1. Nat Immunol (2008) 2.89
Mesenchymal-stem-cell-induced immunoregulation involves FAS-ligand-/FAS-mediated T cell apoptosis. Cell Stem Cell (2012) 2.87
miR-130b Promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1. Cell Stem Cell (2010) 2.87
Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes. J Biol Chem (2004) 2.85
Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations. Mol Cancer Res (2008) 2.82
Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study. Ann Rheum Dis (2010) 2.64
The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation. Science (2014) 2.63
Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b. Nat Immunol (2010) 2.58
Food markets with live birds as source of avian influenza. Emerg Infect Dis (2006) 2.55
Gleevec inhibits beta-amyloid production but not Notch cleavage. Proc Natl Acad Sci U S A (2003) 2.44
Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4. J Gen Virol (2008) 2.41
Chaperones increase association of tau protein with microtubules. Proc Natl Acad Sci U S A (2003) 2.32
Defining the critical hurdles in cancer immunotherapy. J Transl Med (2011) 2.32
Leptin exacerbates collagen-induced arthritis via enhancement of Th17 cell response. Arthritis Rheum (2012) 2.26
Antibodies against H5 and H9 avian influenza among poultry workers in China. N Engl J Med (2009) 2.24
The spike protein of SARS-CoV--a target for vaccine and therapeutic development. Nat Rev Microbiol (2009) 2.23
Inducible microRNA-155 feedback promotes type I IFN signaling in antiviral innate immunity by targeting suppressor of cytokine signaling 1. J Immunol (2010) 2.12
The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon. Nat Immunol (2009) 2.12
APP processing in Alzheimer's disease. Mol Brain (2011) 2.02
Hepatic microenvironment programs hematopoietic progenitor differentiation into regulatory dendritic cells, maintaining liver tolerance. Blood (2008) 2.02
Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus. Arthritis Rheum (2010) 1.98
Altered microRNA expression profile with miR-146a upregulation in CD4+ T cells from patients with rheumatoid arthritis. Arthritis Res Ther (2010) 1.94
Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis. Cancer Res (2003) 1.92
Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation. J Biol Chem (2007) 1.91
Complete genome sequence of bat coronavirus HKU2 from Chinese horseshoe bats revealed a much smaller spike gene with a different evolutionary lineage from the rest of the genome. Virology (2007) 1.89
MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma. J Biol Chem (2011) 1.88
Fas signal promotes lung cancer growth by recruiting myeloid-derived suppressor cells via cancer cell-derived PGE2. J Immunol (2009) 1.85
SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production. Immunity (2006) 1.79
PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1. J Biol Chem (2003) 1.77
MicroRNA-148/152 impair innate response and antigen presentation of TLR-triggered dendritic cells by targeting CaMKIIα. J Immunol (2010) 1.77
Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription. Proc Natl Acad Sci U S A (2009) 1.76
MicroRNA-466l upregulates IL-10 expression in TLR-triggered macrophages by antagonizing RNA-binding protein tristetraprolin-mediated IL-10 mRNA degradation. J Immunol (2010) 1.74
TLR4 signaling promotes immune escape of human lung cancer cells by inducing immunosuppressive cytokines and apoptosis resistance. Mol Immunol (2007) 1.72
Identification of influenza A nucleoprotein as an antiviral target. Nat Biotechnol (2010) 1.71
Increased frequency of circulating follicular helper T cells in patients with rheumatoid arthritis. Clin Dev Immunol (2012) 1.70
CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1. J Immunol (2009) 1.70
Identification and complete genome analysis of three novel paramyxoviruses, Tuhoko virus 1, 2 and 3, in fruit bats from China. Virology (2010) 1.67
Role of leptin in immunity. Cell Mol Immunol (2007) 1.67
Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis. Proc Natl Acad Sci U S A (2008) 1.66
MicroRNA-494 is required for the accumulation and functions of tumor-expanded myeloid-derived suppressor cells via targeting of PTEN. J Immunol (2012) 1.63
Does insulin dysfunction play a role in Alzheimer's disease? Trends Pharmacol Sci (2002) 1.62
Presenilin 1 is required for maturation and cell surface accumulation of nicastrin. J Biol Chem (2002) 1.61
Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression. Proc Natl Acad Sci U S A (2007) 1.61
Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome. Nat Med (2013) 1.61
Epidemiology of hand, foot, and mouth disease and genotype characterization of Enterovirus 71 in Jiangsu, China. J Clin Virol (2010) 1.58
Feline morbillivirus, a previously undescribed paramyxovirus associated with tubulointerstitial nephritis in domestic cats. Proc Natl Acad Sci U S A (2012) 1.55
Interleukin-17 and its expanding biological functions. Cell Mol Immunol (2010) 1.55
Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma. Hepatology (2008) 1.54
Involvement of ERK, p38 and NF-kappaB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cells. Immunology (2002) 1.53
Allogeneic mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus: 4 years of experience. Cell Transplant (2013) 1.53
Coexistence of different genotypes in the same bat and serological characterization of Rousettus bat coronavirus HKU9 belonging to a novel Betacoronavirus subgroup. J Virol (2010) 1.53
Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein. Sci Transl Med (2014) 1.52
Inhibition of amyloid-beta aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761. Proc Natl Acad Sci U S A (2002) 1.51
Increased frequency of follicular helper T cells in patients with autoimmune thyroid disease. J Clin Endocrinol Metab (2011) 1.50
Proteolytic processing of Alzheimer's β-amyloid precursor protein. J Neurochem (2011) 1.50
Tumor-educated CD11bhighIalow regulatory dendritic cells suppress T cell response through arginase I. J Immunol (2009) 1.49
Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory. J Neurochem (2003) 1.47
CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages. Blood (2008) 1.47
Mu-calpain mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus. Brain Res Bull (2008) 1.46
Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Blood (2007) 1.45
Heat shock protein 70, released from heat-stressed tumor cells, initiates antitumor immunity by inducing tumor cell chemokine production and activating dendritic cells via TLR4 pathway. J Immunol (2009) 1.44
Transplantation of human bone marrow mesenchymal stem cell ameliorates the autoimmune pathogenesis in MRL/lpr mice. Cell Mol Immunol (2008) 1.43
Potential roles of insulin and IGF-1 in Alzheimer's disease. Trends Neurosci (2003) 1.43
Phosphorylation of tau antagonizes apoptosis by stabilizing beta-catenin, a mechanism involved in Alzheimer's neurodegeneration. Proc Natl Acad Sci U S A (2007) 1.41
Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation. Proc Natl Acad Sci U S A (2006) 1.41
Isolation and characterization of a novel Betacoronavirus subgroup A coronavirus, rabbit coronavirus HKU14, from domestic rabbits. J Virol (2012) 1.39
Safety of infliximab therapy in rheumatoid arthritis patients with previous exposure to hepatitis B virus. Int J Rheum Dis (2013) 1.39
Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver. Proc Natl Acad Sci U S A (2008) 1.38
Pathological and physiological functions of presenilins. Mol Neurodegener (2006) 1.38
The Th17/Treg imbalance and cytokine environment in peripheral blood of patients with rheumatoid arthritis. Rheumatol Int (2011) 1.37
Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components. J Biol Chem (2005) 1.37
Receptor-binding domain of SARS-CoV spike protein induces long-term protective immunity in an animal model. Vaccine (2006) 1.36