Safety, Immunogenicity, and Protective Efficacy of Intradermal Immunization with Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites in Volunteers Under Chloroquine Prophylaxis: A Randomized Controlled Trial.

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🔗 View Article (PMID 26711509)

Published in Am J Trop Med Hyg on December 28, 2015

Authors

Guido J H Bastiaens1, Maurits P A van Meer1, Anja Scholzen1, Joshua M Obiero1, Mansoureh Vatanshenassan1, Tim van Grinsven1, B Kim Lee Sim1, Peter F Billingsley1, Eric R James1, Anusha Gunasekera1, Else M Bijker1, Geert-Jan van Gemert1, Marga van de Vegte-Bolmer1, Wouter Graumans1, Cornelus C Hermsen1, Quirijn de Mast1, André J A M van der Ven1, Stephen L Hoffman1, Robert W Sauerwein2

Author Affiliations

1: Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands; Sanaria Inc., Rockville, Maryland; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
2: Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands; Sanaria Inc., Rockville, Maryland; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands robert.sauerwein@radboudumc.nl.

Associated clinical trials:

Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis | NCT01728701

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