Current progress in immunotherapy for pancreatic cancer.

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🔗 View Article (PMID 26723878)

Published in Cancer Lett on December 23, 2015

Authors

Kelly Foley1, Victoria Kim2, Elizabeth Jaffee3, Lei Zheng4

Author Affiliations

1: Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States; The Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
2: Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States; The Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
3: Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States; The Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States; The Skip Viragh Center for Pancreatic Cancer Research and Clinical Care, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
4: Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States; The Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States; The Skip Viragh Center for Pancreatic Cancer Research and Clinical Care, Johns Hopkins University School of Medicine, Baltimore, MD, United States. Electronic address: lzheng6@jhmi.edu.

Associated clinical trials:

A Phase 1 Study of Atezolizumab (an Engineered Anti-PDL1 Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors | NCT01375842

Study of BMS-936558 (Nivolumab) Compared to Docetaxel in Previously Treated Metastatic Non-squamous NSCLC (CheckMate057) | NCT01673867

A Phase 1/2 Study to Evaluate MEDI4736 | NCT01693562

A Study of Nivolumab by Itself or Nivolumab Combined With Ipilimumab in Patients With Advanced or Metastatic Solid Tumors | NCT01928394

Phase 2 Study of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors | NCT01876511

Immunotherapy Study for Surgically Resected Pancreatic Cancer | NCT01072981

GVAX Pancreas Vaccine (With CY) and CRS-207 With or Without Nivolumab | NCT02243371

A Global Study to Assess the Effects of MEDI4736, Given as Monotherapy or in Combination With Tremelimumab Determined by PD-L1 Expression Versus Standard of Care in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer (ARCTIC) | NCT02352948

Neoadjuvant/Adjuvant GVAX Pancreas Vaccine (With CY) With or Without Nivolumab Trial for Surgically Resectable Pancreatic Cancer | NCT02451982

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