Published in Breast Cancer Res on January 07, 2016
EWSR1/ELF5 induces acute myeloid leukemia by inhibiting p53/p21 pathway. Cancer Sci (2016) 0.75
Comprehensive landscape of subtype-specific coding and non-coding RNA transcripts in breast cancer. Oncotarget (2016) 0.75
The human genome browser at UCSC. Genome Res (2002) 168.23
Molecular portraits of human breast tumours. Nature (2000) 94.14
Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature (2008) 75.40
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics (2009) 67.17
Integrated genomic analyses of ovarian carcinoma. Nature (2011) 47.72
Comprehensive molecular portraits of human breast tumours. Nature (2012) 47.39
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science (2005) 39.06
SMART, a simple modular architecture research tool: identification of signaling domains. Proc Natl Acad Sci U S A (1998) 36.83
Comprehensive molecular characterization of human colon and rectal cancer. Nature (2012) 34.13
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics (2011) 25.76
Moderated statistical tests for assessing differences in tag abundance. Bioinformatics (2007) 22.87
Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol (2009) 22.22
A scaling normalization method for differential expression analysis of RNA-seq data. Genome Biol (2010) 22.10
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med (2013) 19.87
GENCODE: the reference human genome annotation for The ENCODE Project. Genome Res (2012) 19.19
Comprehensive genomic characterization of squamous cell lung cancers. Nature (2012) 18.90
Small-sample estimation of negative binomial dispersion, with applications to SAGE data. Biostatistics (2007) 18.19
qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data. Genome Biol (2007) 16.15
Integrated genomic characterization of endometrial carcinoma. Nature (2013) 14.29
Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature (2013) 13.60
The somatic genomic landscape of glioblastoma. Cell (2013) 11.73
Comprehensive molecular profiling of lung adenocarcinoma. Nature (2014) 11.02
MapSplice: accurate mapping of RNA-seq reads for splice junction discovery. Nucleic Acids Res (2010) 9.80
Comprehensive molecular characterization of urothelial bladder carcinoma. Nature (2014) 8.48
voom: Precision weights unlock linear model analysis tools for RNA-seq read counts. Genome Biol (2014) 8.13
Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation. Nucleic Acids Res (2012) 7.52
Integrated genomic characterization of papillary thyroid carcinoma. Cell (2014) 6.05
Comprehensive genomic characterization of head and neck squamous cell carcinomas. Nature (2015) 5.50
FOXA1 is a key determinant of estrogen receptor function and endocrine response. Nat Genet (2010) 5.22
Molecular biology of the Ets family of transcription factors. Gene (2003) 4.41
Genomic Classification of Cutaneous Melanoma. Cell (2015) 3.91
The 5-methylcytosine content of DNA from human tumors. Nucleic Acids Res (1983) 3.51
Cancer-associated regulation of alternative splicing. Nat Struct Mol Biol (2009) 3.35
VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma. Cancer Res (2002) 3.19
Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5. Nat Cell Biol (2008) 2.77
Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2. Nat Cell Biol (2012) 2.46
Specificity within the ets family of transcription factors. Adv Cancer Res (1998) 2.21
The somatic genomic landscape of chromophobe renal cell carcinoma. Cancer Cell (2014) 2.21
The Ets transcription factor Elf5 specifies mammary alveolar cell fate. Genes Dev (2008) 2.13
Robustly detecting differential expression in RNA sequencing data using observation weights. Nucleic Acids Res (2014) 2.10
Polymerization of the SAM domain of TEL in leukemogenesis and transcriptional repression. EMBO J (2001) 2.03
Regulation of Ets function by protein - protein interactions. Oncogene (2000) 1.93
Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning. Development (2005) 1.75
An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors. Genes Dev (2002) 1.73
Changes in the expression of many Ets family transcription factors and of potential target genes in normal mammary tissue and tumors. J Biol Chem (2003) 1.72
Profile of Ets gene expression in human breast carcinoma. Cancer Biol Ther (2007) 1.65
Microarray analysis reveals distinct gene expression profiles among different histologic types of endometrial cancer. Cancer Res (2003) 1.54
Elf5 inhibits TGF-β-driven epithelial-mesenchymal transition in prostate cancer by repressing SMAD3 activation. Prostate (2015) 1.47
Characterization of ESE-2, a novel ESE-1-related Ets transcription factor that is restricted to glandular epithelium and differentiated keratinocytes. J Biol Chem (1999) 1.28
pHUSH: a single vector system for conditional gene expression. BMC Biotechnol (2007) 1.27
A novel transcription factor, ELF5, belongs to the ELF subfamily of ETS genes and maps to human chromosome 11p13-15, a region subject to LOH and rearrangement in human carcinoma cell lines. Oncogene (1998) 1.27
Alternative transcription and alternative splicing in cancer. Pharmacol Ther (2012) 1.22
RNA recognition via the SAM domain of Smaug. Mol Cell (2003) 1.22
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. PLoS Biol (2012) 1.16
Molecular mechanisms of ETS transcription factor-mediated tumorigenesis. Crit Rev Biochem Mol Biol (2013) 1.08
Detection of recurrent alternative splicing switches in tumor samples reveals novel signatures of cancer. Nucleic Acids Res (2015) 1.06
The ETS transcription factor ESE-1 transforms MCF-12A human mammary epithelial cells via a novel cytoplasmic mechanism. Mol Cell Biol (2004) 1.02
PDEF promotes luminal differentiation and acts as a survival factor for ER-positive breast cancer cells. Cancer Cell (2013) 1.01
A major site of expression of the ets transcription factor Elf5 is epithelia of exocrine glands. Histochem Cell Biol (2004) 0.97
Lineage specific methylation of the Elf5 promoter in mammary epithelial cells. Stem Cells (2011) 0.97
Determination of the consensus DNA-binding sequence and a transcriptional activation domain for ESE-2. Biochem J (2006) 0.95
Transducin-like enhancer protein 1 mediates estrogen receptor binding and transcriptional activity in breast cancer cells. Proc Natl Acad Sci U S A (2011) 0.93
Binding of the C-terminal sterile alpha motif (SAM) domain of human p73 to lipid membranes. J Biol Chem (2003) 0.93
Misexpression of ELF5 disrupts lung branching and inhibits epithelial differentiation. Dev Biol (2008) 0.90
Transcriptome instability as a molecular pan-cancer characteristic of carcinomas. BMC Genomics (2014) 0.89
Analysis of differentially expressed genes in LNCaP prostate cancer progression model. J Androl (2010) 0.86
Novel TNS3-MAP3K3 and ZFPM2-ELF5 fusion genes identified by RNA sequencing in multicystic mesothelioma with t(7;17)(p12;q23) and t(8;11)(q23;p13). Cancer Lett (2014) 0.86
Ets-1 p27: a novel Ets-1 isoform with dominant-negative effects on the transcriptional properties and the subcellular localization of Ets-1 p51. Oncogene (2009) 0.83
Epigenetic regulation of Elf5 is associated with epithelial-mesenchymal transition in urothelial cancer. PLoS One (2015) 0.82
Mapping of ESE-1 subdomains required to initiate mammary epithelial cell transformation via a cytoplasmic mechanism. Mol Cancer (2011) 0.80
The Ets transcription factor ELF5 functions as a tumor suppressor in the kidney. Twin Res Hum Genet (2011) 0.79
ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells. PLoS Biol (2015) 0.78