Published in Cell Biosci on February 03, 2016
A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. N Engl J Med (1999) 11.62
Introduction to NF-kappaB: players, pathways, perspectives. Oncogene (2006) 7.78
Tumour necrosis factor and cancer. Nat Rev Cancer (2009) 6.27
The TRAIL apoptotic pathway in cancer onset, progression and therapy. Nat Rev Cancer (2008) 4.42
Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis. Nat Med (2006) 3.79
Deubiquitylation and regulation of the immune response. Nat Rev Immunol (2008) 3.59
NF-κB in the liver--linking injury, fibrosis and hepatocellular carcinoma. Nat Rev Gastroenterol Hepatol (2011) 3.28
TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer. Cancer Cell (2010) 3.25
Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice. Gastroenterology (1999) 3.24
Mechanisms of Liver Injury. II. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions. Am J Physiol Gastrointest Liver Physiol (2006) 3.05
From bench to clinic with apoptosis-based therapeutic agents. Nature (2000) 2.96
Hepatocellular carcinoma. J Hepatol (2000) 2.77
Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis. Proc Natl Acad Sci U S A (2009) 2.68
Tumor necrosis factor: an apoptosis JuNKie? Cell (2004) 2.64
Reactive oxygen and mechanisms of inflammatory liver injury: Present concepts. J Gastroenterol Hepatol (2011) 2.19
Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice. Hepatology (2003) 2.00
TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation. J Leukoc Biol (2011) 1.98
Mechanisms of hepatic toxicity. I. TNF-induced liver injury. Am J Physiol (1998) 1.89
Tumor promotion via injury- and death-induced inflammation. Immunity (2011) 1.81
Neutrophil-induced liver cell injury in endotoxin shock is a CD11b/CD18-dependent mechanism. Am J Physiol (1991) 1.59
Tumor necrosis factor alpha in the pathogenesis of human and murine fulminant hepatic failure. Gastroenterology (2000) 1.49
Functional inactivation of neutrophils with a Mac-1 (CD11b/CD18) monoclonal antibody protects against ischemia-reperfusion injury in rat liver. Hepatology (1993) 1.47
Prevention of carbon tetrachloride-induced rat liver injury by soluble tumor necrosis factor receptor. Gastroenterology (1995) 1.36
Review: cytokines and the pathogenesis of multiple sclerosis. J Neurosci Res (1996) 1.30
Neutrophilic infiltration in alcoholic hepatitis. Alcohol (2002) 1.19
Role of neutrophils in a mouse model of halothane-induced liver injury. Hepatology (2006) 1.19
Genome-wide screening reveals that miR-195 targets the TNF-α/NF-κB pathway by down-regulating IκB kinase alpha and TAB3 in hepatocellular carcinoma. Hepatology (2013) 1.16
TNFR1 mediates TNF-α-induced tumour lymphangiogenesis and metastasis by modulating VEGF-C-VEGFR3 signalling. Nat Commun (2014) 1.11
Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ. Nat Immunol (2013) 1.08
miR-15b and miR-16 regulate TNF mediated hepatocyte apoptosis via BCL2 in acute liver failure. Apoptosis (2012) 1.04
Mechanisms of circadian rhythmicity of carbon tetrachloride hepatotoxicity. J Pharmacol Exp Ther (2002) 1.03
TNF-alpha, IL-4, and IFN-gamma regulate differential expression of P- and E-selectin expression by porcine aortic endothelial cells. J Immunol (2000) 0.92
Potential epigenetic mechanism in non-alcoholic Fatty liver disease. Int J Mol Sci (2015) 0.84
Protective effects of allopurinol against acute liver damage and cirrhosis induced by carbon tetrachloride: modulation of NF-κB, cytokine production and oxidative stress. Biochim Biophys Acta (2011) 0.80
Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial-mesenchymal transition in hepatocellular carcinoma. Cancer Lett (2014) 1.35
Autophagy protects against palmitate-induced apoptosis in hepatocytes. Cell Biosci (2014) 1.23
Toll like receptor 4 facilitates invasion and migration as a cancer stem cell marker in hepatocellular carcinoma. Cancer Lett (2014) 0.83
Hepatitis B virus (HBV) receptors: Deficiency in tumor results in scant HBV infection and overexpression in peritumor leads to higher recurrence risk. Oncotarget (2015) 0.81
Lipopolysaccharide supports maintaining the stemness of CD133(+) hepatoma cells through activation of the NF-κB/HIF-1α pathway. Cancer Lett (2016) 0.78
Autophagy-deficient Kupffer cells promote tumorigenesis by enhancing mtROS-NF-κB-IL1α/β-dependent inflammation and fibrosis during the preneoplastic stage of hepatocarcinogenesis. Cancer Lett (2016) 0.76
Kupffer cells-dependent inflammation in the injured liver increases recruitment of mesenchymal stem cells in aging mice. Oncotarget (2016) 0.76
Alcohol Disrupts Human Liver Stem/Progenitor Cell Proliferation and Differentiation. J Stem Cell Res Ther (2014) 0.75
The injured liver induces hyperimmunoglobulinemia by failing to dispose of antigens and endotoxins in the portal system. PLoS One (2015) 0.75
Lipopolysaccharide promotes tumorigenicity of hepatic progenitor cells by promoting proliferation and blocking normal differentiation. Cancer Lett (2016) 0.75