Mitochondria are required for pro-ageing features of the senescent phenotype.

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Published in EMBO J on February 04, 2016

Authors

Clara Correia-Melo1, Francisco D M Marques2, Rhys Anderson2, Graeme Hewitt2, Rachael Hewitt3, John Cole3, Bernadette M Carroll2, Satomi Miwa2, Jodie Birch2, Alina Merz2, Michael D Rushton2, Michelle Charles2, Diana Jurk2, Stephen W G Tait3, Rafal Czapiewski2, Laura Greaves4, Glyn Nelson2, Mohammad Bohlooly-Y5, Sergio Rodriguez-Cuenca6, Antonio Vidal-Puig6, Derek Mann7, Gabriele Saretzki2, Giovanni Quarato8, Douglas R Green8, Peter D Adams3, Thomas von Zglinicki2, Viktor I Korolchuk2, João F Passos9

Author Affiliations

1: Institute for Cell and Molecular Biosciences, Campus for Ageing and Vitality, Newcastle University Institute for Ageing, Newcastle University, Newcastle upon Tyne, UK GABBA Program, Abel Salazar Biomedical Sciences Institute University of Porto, Porto, Portugal.
2: Institute for Cell and Molecular Biosciences, Campus for Ageing and Vitality, Newcastle University Institute for Ageing, Newcastle University, Newcastle upon Tyne, UK.
3: Institute of Cancer Sciences, CR-UK Beatson Institute, University of Glasgow, Glasgow, UK.
4: Wellcome Trust Centre for Mitochondrial Research, Newcastle University Centre for Brain Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK.
5: Transgenic RAD, Discovery Sciences, AstraZeneca, Mölndal, Sweden.
6: Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
7: Faculty of Medical Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
8: Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
9: Institute for Cell and Molecular Biosciences, Campus for Ageing and Vitality, Newcastle University Institute for Ageing, Newcastle University, Newcastle upon Tyne, UK joao.passos@ncl.ac.uk.

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