Published in Placenta on December 24, 2015
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Random-effects models for longitudinal data. Biometrics (1982) 54.17
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet (2007) 14.99
Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet (2007) 13.62
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol (2011) 5.96
An obesity-associated FTO gene variant and increased energy intake in children. N Engl J Med (2008) 5.88
Obesity-associated variants within FTO form long-range functional connections with IRX3. Nature (2014) 5.61
Cohort profile: The Southampton Women's Survey. Int J Epidemiol (2005) 4.11
Obesity associated genetic variation in FTO is associated with diminished satiety. J Clin Endocrinol Metab (2008) 3.80
Life course variations in the associations between FTO and MC4R gene variants and body size. Hum Mol Genet (2009) 2.22
A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. Proc Natl Acad Sci U S A (2010) 2.12
Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations. Am J Hum Genet (2009) 2.09
How does body fat influence bone mass in childhood? A Mendelian randomization approach. J Bone Miner Res (2009) 2.01
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet (2012) 1.90
Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development. PLoS Genet (2011) 1.82
The common obesity variant near MC4R gene is associated with higher intakes of total energy and dietary fat, weight change and diabetes risk in women. Hum Mol Genet (2008) 1.79
Increasing heritability of BMI and stronger associations with the FTO gene over childhood. Obesity (Silver Spring) (2008) 1.77
Calculation of unconditional and conditional reference intervals for foetal size and growth from longitudinal measurements. Stat Med (1995) 1.67
The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice. PLoS One (2010) 1.67
The association between the FTO gene and fat mass in humans develops by the postnatal age of two weeks. J Clin Endocrinol Metab (2008) 1.45
Developmental plasticity and developmental origins of non-communicable disease: theoretical considerations and epigenetic mechanisms. Prog Biophys Mol Biol (2011) 1.40
Impact on weight dynamics and general growth of the common FTO rs9939609: a longitudinal Danish cohort study. Int J Obes (Lond) (2008) 1.34
Placental transport of leucine, phenylalanine, glycine, and proline in intrauterine growth-restricted pregnancies. J Clin Endocrinol Metab (2001) 1.31
Common genetic variation near MC4R is associated with eating behaviour patterns in European populations. Int J Obes (Lond) (2009) 1.30
Role for the obesity-related FTO gene in the cellular sensing of amino acids. Proc Natl Acad Sci U S A (2013) 1.24
Childhood obesity: are genetic differences involved? Am J Clin Nutr (2009) 1.19
Measurement of housekeeping genes in human placenta. Placenta (2009) 1.18
FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. Hum Mol Genet (2014) 1.11
Influence of prenatal nutrition and obesity on tissue specific fat mass and obesity-associated (FTO) gene expression. Reproduction (2010) 0.97
The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men. Neurobiol Aging (2011) 0.95
Irx3 and Pax6 establish differential competence for Shh-mediated induction of GABAergic and glutamatergic neurons of the thalamus. Proc Natl Acad Sci U S A (2013) 0.92
The placental exposome: placental determinants of fetal adiposity and postnatal body composition. Ann Nutr Metab (2013) 0.88
Maternal dietary glycemic index and glycemic load in early pregnancy are associated with offspring adiposity in childhood: the Southampton Women's Survey. Am J Clin Nutr (2014) 0.87
Placental FTO expression relates to fetal growth. Int J Obes (Lond) (2010) 0.83
Association between a common variant near MC4R and change in body mass index develops by two weeks of age. Horm Res Paediatr (2010) 0.83
Early risk determinants and later health outcomes: implications for research prioritization and the food supply. Summary of the workshop. Am J Clin Nutr (2009) 0.82
Defining the genetic architecture of the predisposition to obesity: a challenging but not insurmountable task. Am J Clin Nutr (2009) 0.81
Fat mass and obesity-associated obesity-risk genotype is associated with lower foetal growth: an effect that is reversed in the offspring of smoking mothers. J Dev Orig Health Dis (2012) 0.78
Placental expression of the obesity-associated gene FTO is reduced by fetal growth restriction but not by macrosomia in rats and humans. J Dev Orig Health Dis (2013) 0.77