Published in Proc Natl Acad Sci U S A on March 07, 2016
Whole-exome sequencing identifies multiple loss-of-function mutations of NF-κB pathway regulators in nasopharyngeal carcinoma. Proc Natl Acad Sci U S A (2016) 0.77
Epigenetic Basis of Cancer Health Disparities: Looking Beyond Genetic Differences. Biochim Biophys Acta (2017) 0.76
Excavation of attractor modules for nasopharyngeal carcinoma via integrating systemic module inference with attract method. Braz J Med Biol Res (2017) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics (2009) 190.94
A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat Genet (2011) 59.36
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res (2010) 43.51
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics (2011) 25.76
Protective and pathogenic functions of macrophage subsets. Nat Rev Immunol (2011) 12.21
The enigmatic epidemiology of nasopharyngeal carcinoma. Cancer Epidemiol Biomarkers Prev (2006) 6.61
Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology. PLoS Genet (2011) 6.20
Second-generation PLINK: rising to the challenge of larger and richer datasets. Gigascience (2015) 5.06
A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. Nat Genet (2010) 2.62
The genomic landscape of nasopharyngeal carcinoma. Nat Genet (2014) 2.39
Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms. J Immunol (2008) 2.26
The UCSC Genome Browser database: 2016 update. Nucleic Acids Res (2015) 2.18
A comprehensive framework for prioritizing variants in exome sequencing studies of Mendelian diseases. Nucleic Acids Res (2012) 2.08
The MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocyte migration. Dev Cell (2003) 1.91
Detecting false-positive signals in exome sequencing. Hum Mutat (2012) 1.87
DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach. Nucleic Acids Res (2014) 1.64
Genome-wide expression profiling reveals EBV-associated inhibition of MHC class I expression in nasopharyngeal carcinoma. Cancer Res (2006) 1.62
Anti-angiogenic and tumor-suppressive roles of candidate tumor-suppressor gene, Fibulin-2, in nasopharyngeal carcinoma. Oncogene (2011) 1.31
Truncated RON tyrosine kinase drives tumor cell progression and abrogates cell-cell adhesion through E-cadherin transcriptional repression. Cancer Res (2004) 1.26
RASSF1A is a target tumor suppressor from 3p21.3 in nasopharyngeal carcinoma. Int J Cancer (2004) 1.23
High frequency of chromosome 3p deletion in histologically normal nasopharyngeal epithelia from southern Chinese. Cancer Res (2000) 1.17
The envelope glycoprotein of friend spleen focus-forming virus covalently interacts with and constitutively activates a truncated form of the receptor tyrosine kinase Stk. J Virol (2001) 1.15
Functional evidence for a nasopharyngeal carcinoma tumor suppressor gene that maps at chromosome 3p21.3. Proc Natl Acad Sci U S A (1998) 1.12
Macrophage-stimulating protein and RON receptor tyrosine kinase: potential regulators of macrophage inflammatory activities. Scand J Immunol (2002) 1.07
Functional analysis of a cell cycle-associated, tumor-suppressive gene, protein tyrosine phosphatase receptor type G, in nasopharyngeal carcinoma. Cancer Res (2008) 1.07
Role of macrophage-stimulating protein and its receptor, RON tyrosine kinase, in ciliary motility. J Clin Invest (1997) 1.07
Innate immune cells in inflammation and cancer. Cancer Immunol Res (2013) 1.06
Identification of a tumor suppressive critical region mapping to 3p14.2 in esophageal squamous cell carcinoma and studies of a candidate tumor suppressor gene, ADAMTS9. Oncogene (2006) 1.05
Family-based association analysis validates chromosome 3p21 as a putative nasopharyngeal carcinoma susceptibility locus. Genet Med (2006) 1.03
p16 gene alterations in nasopharyngeal carcinoma. Cancer Res (1995) 1.02
The RON receptor tyrosine kinase regulates IFN-gamma production and responses in innate immunity. J Immunol (2008) 1.01
Inhibition of TLR4-induced IκB kinase activity by the RON receptor tyrosine kinase and its ligand, macrophage-stimulating protein. J Immunol (2010) 0.97
Frequent chromosome 9p losses in histologically normal nasopharyngeal epithelia from southern Chinese. Int J Cancer (2002) 0.95
Familial and large-scale case-control studies identify genes associated with nasopharyngeal carcinoma. Semin Cancer Biol (2012) 0.93
MEXPRESS: visualizing expression, DNA methylation and clinical TCGA data. BMC Genomics (2015) 0.87
A functional investigation of tumor suppressor gene activities in a nasopharyngeal carcinoma cell line HONE1 using a monochromosome transfer approach. Genes Chromosomes Cancer (2000) 0.87
Comparative methylome analysis in solid tumors reveals aberrant methylation at chromosome 6p in nasopharyngeal carcinoma. Cancer Med (2015) 0.85
PTPRG suppresses tumor growth and invasion via inhibition of Akt signaling in nasopharyngeal carcinoma. Oncotarget (2015) 0.82
Regulation of Macrophage Polarization by RON Receptor Tyrosine Kinase Signaling. Front Immunol (2014) 0.82
RON receptor tyrosine kinase, a negative regulator of inflammation, is decreased during simian immunodeficiency virus-associated central nervous system disease. J Immunol (2013) 0.79
Anti-angiogenic pathway associations of the 3p21.3 mapped BLU gene in nasopharyngeal carcinoma. Oncogene (2014) 0.77