Published in Oncogene on July 11, 2011
The transcriptional landscape and mutational profile of lung adenocarcinoma. Genome Res (2012) 3.80
ISOexpresso: a web-based platform for isoform-level expression analysis in human cancer. BMC Genomics (2016) 1.39
Detection of recurrent alternative splicing switches in tumor samples reveals novel signatures of cancer. Nucleic Acids Res (2015) 1.06
The interplay of host genetic factors and Epstein-Barr virus in the development of nasopharyngeal carcinoma. Chin J Cancer (2014) 1.04
Identification of recurrent regulated alternative splicing events across human solid tumors. Nucleic Acids Res (2015) 1.03
An excess of deleterious variants in VEGF-A pathway genes in Down-syndrome-associated atrioventricular septal defects. Am J Hum Genet (2012) 1.01
Integrative DNA methylation and gene expression analysis in high-grade soft tissue sarcomas. Genome Biol (2013) 0.97
Overexpression of EFEMP1 correlates with tumor progression and poor prognosis in human ovarian carcinoma. PLoS One (2013) 0.94
Integrated mRNA and microRNA transcriptome sequencing characterizes sequence variants and mRNA-microRNA regulatory network in nasopharyngeal carcinoma model systems. FEBS Open Bio (2014) 0.93
Fibulin-2 is a driver of malignant progression in lung adenocarcinoma. PLoS One (2013) 0.89
Th-MYCN mice with caspase-8 deficiency develop advanced neuroblastoma with bone marrow metastasis. Cancer Res (2013) 0.88
Interaction between the ADAMTS-12 metalloprotease and fibulin-2 induces tumor-suppressive effects in breast cancer cells. Oncotarget (2014) 0.85
Novel paracrine modulation of Notch-DLL4 signaling by fibulin-3 promotes angiogenesis in high-grade gliomas. Cancer Res (2014) 0.85
Tumor suppressor genes on frequently deleted chromosome 3p in nasopharyngeal carcinoma. Chin J Cancer (2012) 0.85
Alterations of the WNT7A gene in clear cell renal cell carcinomas. PLoS One (2012) 0.82
NotI microarrays: novel epigenetic markers for early detection and prognosis of high grade serous ovarian cancer. Int J Mol Sci (2012) 0.82
Fibulin 2, a tyrosine O-sulfated protein, is up-regulated following retinal detachment. J Biol Chem (2014) 0.80
Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinoma. Proc Natl Acad Sci U S A (2016) 0.79
Regulation of fibulin-2 gene expression by integrin α3β1 contributes to the invasive phenotype of transformed keratinocytes. J Invest Dermatol (2014) 0.79
A C-terminal fragment of fibulin-7 interacts with endothelial cells and inhibits their tube formation in culture. Arch Biochem Biophys (2014) 0.78
Fibulin-4 is associated with tumor progression and a poor prognosis in ovarian carcinomas. BMC Cancer (2015) 0.77
Anti-angiogenic pathway associations of the 3p21.3 mapped BLU gene in nasopharyngeal carcinoma. Oncogene (2014) 0.77
A network biology approach to discover the molecular biomarker associated with hepatocellular carcinoma. Biomed Res Int (2014) 0.77
Integrin α9 gene promoter is hypermethylated and downregulated in nasopharyngeal carcinoma. Oncotarget (2015) 0.76
Novel lentiviral-inducible transgene expression systems and versatile single-plasmid reporters for in vitro and in vivo cancer biology studies. Cancer Gene Ther (2015) 0.76
Differential proteomics analysis of low- and high-grade of astrocytoma using iTRAQ quantification. Onco Targets Ther (2016) 0.75
Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells. Oncotarget (2017) 0.75
Fibulin-4 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition via the PI3K/Akt/mTOR pathway. Int J Oncol (2017) 0.75
Metastasis-suppressing NID2, an epigenetically-silenced gene, in the pathogenesis of nasopharyngeal carcinoma and esophageal squamous cell carcinoma. Oncotarget (2016) 0.75
Fibulin-4 is associated with prognosis of endometrial cancer patients and inhibits cancer cell invasion and metastasis via Wnt/β-catenin signaling pathway. Oncotarget (2017) 0.75
Identification of novel methylated targets in colorectal cancer by microarray analysis and construction of co-expression network. Oncol Lett (2017) 0.75
Loss of fibulin-2 expression is involved in the inhibition of breast cancer invasion and forms a new barrier in addition to the basement membrane. Oncol Lett (2017) 0.75
Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem Pharmacol (1973) 47.81
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell (1998) 13.98
A physical map of the human genome. Nature (2001) 12.39
The DNA sequence of human chromosome 21. Nature (2000) 10.66
Small GTP-binding proteins. Physiol Rev (2001) 9.52
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes Dev (1999) 6.93
Hd1, a major photoperiod sensitivity quantitative trait locus in rice, is closely related to the Arabidopsis flowering time gene CONSTANS. Plant Cell (2000) 6.93
A high-density rice genetic linkage map with 2275 markers using a single F2 population. Genetics (1998) 6.82
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice. Curr Biol (1998) 6.38
Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease. N Engl J Med (1999) 5.61
Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature (2001) 5.07
Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP. Nature (1998) 4.95
Oligonucleotide probes complementary to variable regions of ribosomal RNA discriminate between Mycoplasma species. J Gen Microbiol (1987) 4.74
T cell-specific loss of Pten leads to defects in central and peripheral tolerance. Immunity (2001) 4.62
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Nat Genet (2001) 4.54
The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development. Cell (2000) 4.53
Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells. Respir Res (2005) 4.41
Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells. Proc Natl Acad Sci U S A (1990) 4.40
Osteoblastic cells are involved in osteoclast formation. Endocrinology (1988) 4.37
Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells. J Cell Biol (1997) 4.27
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b. Nature (2000) 4.08
Development of a syngeneic mouse model for events related to ovarian cancer. Carcinogenesis (2000) 4.06
Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway. J Cell Biol (1996) 4.06
Is physical activity or physical fitness more important in defining health benefits? Med Sci Sports Exerc (2001) 3.90
Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI). J Cell Biol (1993) 3.87
Tropism of avian influenza A (H5N1) in the upper and lower respiratory tract. Nat Med (2007) 3.75
Incorporation of 3H-uridine and 3H-uracil into RNA: a simple technique for the detection of mycoplasma contamination of cultured cells. Exp Cell Res (1974) 3.73
Angiogenic and HIV-inhibitory functions of KSHV-encoded chemokines. Science (1997) 3.70
Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes. EMBO J (2000) 3.32
Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein. J Biol Chem (1997) 3.08
Rice gibberellin-insensitive dwarf mutant gene Dwarf 1 encodes the alpha-subunit of GTP-binding protein. Proc Natl Acad Sci U S A (1999) 2.97
Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction. J Biol Chem (1992) 2.90
Cerebral vasospasm following aneurysmal subarachnoid hemorrhage. Stroke (1985) 2.89
Nucleotide sequence of the 3' end of MCF 247 murine leukemia virus. J Virol (1983) 2.87
Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer. Am J Pathol (2001) 2.86
The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells. Endocrinology (1989) 2.83
Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae. EMBO J (1997) 2.80
Large-scale EST sequencing in rice. Plant Mol Biol (1997) 2.80
Synthetic oligonucleotide probes complementary to rRNA for group- and species-specific detection of mycoplasmas. Isr J Med Sci (1987) 2.76
Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility. Mol Cell Biol (1993) 2.71
Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins. J Biol Chem (1993) 2.62
Seed plant phylogeny inferred from all three plant genomes: monophyly of extant gymnosperms and origin of Gnetales from conifers. Proc Natl Acad Sci U S A (2000) 2.61
Rapid reorganization of resistance gene homologues in cereal genomes. Proc Natl Acad Sci U S A (1998) 2.53
Characteristics of macrolide-resistant Mycoplasma pneumoniae strains isolated from patients and induced with erythromycin in vitro. Microbiol Immunol (2001) 2.52
Introduction of a normal human chromosome 11 into a Wilms' tumor cell line controls its tumorigenic expression. Science (1987) 2.52
Rho as a regulator of the cytoskeleton. Trends Biochem Sci (1995) 2.52
Expression of Xa1, a bacterial blight-resistance gene in rice, is induced by bacterial inoculation. Proc Natl Acad Sci U S A (1998) 2.49
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling. Nature (2001) 2.47
An improved technique for the efficient construction of gene libraries by partial filling-in of cohesive ends. Gene (1986) 2.47
Rituximab-associated hepatitis B virus (HBV) reactivation in lymphoproliferative diseases: meta-analysis and examination of FDA safety reports. Ann Oncol (2010) 2.46
Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment. Oncogene (1994) 2.45
Helicobacter pylori arginase inhibits nitric oxide production by eukaryotic cells: a strategy for bacterial survival. Proc Natl Acad Sci U S A (2001) 2.43
Human MN/CA9 gene, a novel member of the carbonic anhydrase family: structure and exon to protein domain relationships. Genomics (1996) 2.34
Analysis of the genomes of mink cell focus-inducing murine type-C viruses: a progress report. Cold Spring Harb Symp Quant Biol (1980) 2.34
Translocation of activated Rho from the cytoplasm to membrane ruffling area, cell-cell adhesion sites and cleavage furrows. Oncogene (1995) 2.32
SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival. Genes Dev (1999) 2.31
Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding. EMBO J (1999) 2.28
Isolation and characterization of a novel actin filament-binding protein from Saccharomyces cerevisiae. Oncogene (1998) 2.27
Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor. Curr Biol (1998) 2.26
Cloning and characterization of cell adhesion kinase beta, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily. J Biol Chem (1995) 2.26
Evidence of three-dimensional scroll waves with ribbon-shaped filament as a mechanism of ventricular tachycardia in the isolated rabbit heart. J Cardiovasc Electrophysiol (1999) 2.24
CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus. Neuron (2001) 2.22
Hd6, a rice quantitative trait locus involved in photoperiod sensitivity, encodes the alpha subunit of protein kinase CK2. Proc Natl Acad Sci U S A (2001) 2.22
Risk factors for primary dysfunction after liver transplantation--a multivariate analysis. Transplantation (1993) 2.20
Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes. Proc Natl Acad Sci U S A (1998) 2.20
The Pib gene for rice blast resistance belongs to the nucleotide binding and leucine-rich repeat class of plant disease resistance genes. Plant J (1999) 2.18
Human cell hybrids: analysis of transformation and tumorigenicity. Science (1982) 2.16
Suppression of the heterotrimeric G protein causes abnormal morphology, including dwarfism, in rice. Proc Natl Acad Sci U S A (1999) 2.15
Virtual electrode-induced phase singularity: a basic mechanism of defibrillation failure. Circ Res (1998) 2.15
rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells. Mol Cell Biol (1994) 2.12
Introduction of human chromosome 11 via microcell transfer controls tumorigenic expression of HeLa cells. EMBO J (1986) 2.11
Identification of a new variable sequence in the P1 cytadhesin gene of Mycoplasma pneumoniae: evidence for the generation of antigenic variation by DNA recombination between repetitive sequences. Infect Immun (1999) 2.11
Prospective reliability of the STRokE DOC wireless/site independent telemedicine system. Neurology (2005) 2.08
Characterization of the DNA polymerases induced by a group of herpes simplex virus type I variants selected for growth in the presence of phosphonoformic acid. J Biol Chem (1982) 2.08
VHL gene inactivation in an endolymphatic sac tumor associated with von Hippel-Lindau disease. Neurology (1999) 2.08
Tumorigenicity in human melanoma cell lines controlled by introduction of human chromosome 6. Science (1990) 2.07
A vital role for glycosphingolipid synthesis during development and differentiation. Proc Natl Acad Sci U S A (1999) 2.05
An informative linkage map of soybean reveals QTLs for flowering time, leaflet morphology and regions of segregation distortion. DNA Res (2001) 2.03
Role of vascular endothelial growth factor C expression in the development of lymph node metastasis in gastric cancer. Clin Cancer Res (1999) 2.03
INE: a rice genome database with an integrated map view. Nucleic Acids Res (2000) 2.00
A putative Ca2+-binding protein: structure of the light subunit of porcine calpain elucidated by molecular cloning and protein sequence analysis. Proc Natl Acad Sci U S A (1985) 1.99
The evaluation of the JEWEL project: an innovative economic enhancement and HIV prevention intervention study targeting drug using women involved in prostitution. AIDS Care (2006) 1.98
Kinetics of defibrillation shock-induced response: design implications for the optimal defibrillation waveform. Europace (2002) 1.97
The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin. J Biol Chem (1999) 1.97
Identification of the MN/CA9 protein as a reliable diagnostic biomarker of clear cell carcinoma of the kidney. Cancer Res (1997) 1.96
Arabidopsis-rice: will colinearity allow gene prediction across the eudicot-monocot divide? Genome Res (1999) 1.92
Cloned mycoplasma ribosomal RNA genes for the detection of mycoplasma contamination in tissue cultures. Science (1984) 1.92
Evaluation of immunoreactivity for erbB-2 protein as a marker of poor short term prognosis in gastric cancer. Cancer Res (1991) 1.92
The lipid phosphatase SHIP2 controls insulin sensitivity. Nature (2001) 1.90
Involvement of Rho p21 small GTP-binding protein and its regulator in the HGF-induced cell motility. Oncogene (1994) 1.89
Mutation of K-ras protooncogene in human ovarian epithelial tumors of borderline malignancy. Cancer Res (1993) 1.89
Purification and partial characterization of the principal deoxyribonucleic acid polymerase from Mycoplasmatales. J Bacteriol (1977) 1.88
Bifidobacterium longum as a delivery system for gene therapy of chemically induced rat mammary tumors. Breast Cancer Res Treat (2001) 1.88
Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity. Biochem Pharmacol (2000) 1.87
Structure of the Sec23p/24p and Sec13p/31p complexes of COPII. Proc Natl Acad Sci U S A (2001) 1.84
Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation. Oncogene (2006) 1.82
Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training. J Clin Invest (2000) 1.81
The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis. Proc Natl Acad Sci U S A (2001) 1.81