Published in PLoS Genet on March 15, 2016
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Enhanced expression of asparagine synthetase under glucose-deprived conditions protects pancreatic cancer cells from apoptosis induced by glucose deprivation and cisplatin. Cancer Res (2007) 1.23
Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death. Mol Syst Biol (2012) 1.20
Intestinal epithelial cancer cell anoikis resistance: EGFR-mediated sustained activation of Src overrides Fak-dependent signaling to MEK/Erk and/or PI3-K/Akt-1. J Cell Biochem (2009) 1.13
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Protein kinase A activation confers resistance to trastuzumab in human breast cancer cell lines. Clin Cancer Res (2009) 1.10
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Glucose starvation induces cell death in K-ras-transformed cells by interfering with the hexosamine biosynthesis pathway and activating the unfolded protein response. Cell Death Dis (2013) 1.05
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Beyond Warburg effect--dual metabolic nature of cancer cells. Sci Rep (2014) 1.02
STAT3 induces anoikis resistance, promotes cell invasion and metastatic potential in pancreatic cancer cells. Carcinogenesis (2014) 1.01
Oncogenic K-ras expression is associated with derangement of the cAMP/PKA pathway and forskolin-reversible alterations of mitochondrial dynamics and respiration. Oncogene (2012) 1.01
The regulation of cancer cell death and metabolism by extracellular matrix attachment. Semin Cell Dev Biol (2012) 1.01
p58(IPK)-mediated attenuation of the proapoptotic PERK-CHOP pathway allows malignant progression upon low glucose. Mol Cell (2013) 1.00
PKA signaling drives mammary tumorigenesis through Src. Oncogene (2014) 0.99
An mTORC1-Mdm2-Drosha axis for miRNA biogenesis in response to glucose- and amino acid-deprivation. Mol Cell (2015) 0.97
Isotope cluster-based compound matching in gas chromatography/mass spectrometry for non-targeted metabolomics. Anal Chem (2013) 0.97
Role of cAMP in the regulation of hepatocytic autophagy. Eur J Biochem (1996) 0.96
Antioxidant enzymes mediate survival of breast cancer cells deprived of extracellular matrix. Cancer Res (2013) 0.95
Glucose-starved cells do not engage in prosurvival autophagy. J Biol Chem (2013) 0.94
Tissue specificity of mitochondrial glutamate pathways and the control of metabolic homeostasis. Biochim Biophys Acta (2008) 0.94
A dominant negative RAS-specific guanine nucleotide exchange factor reverses neoplastic phenotype in K-ras transformed mouse fibroblasts. Oncogene (2000) 0.94
Biochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window". Sci Rep (2015) 0.94
Ras and autophagy in cancer development and therapy. Oncotarget (2014) 0.93
High expression of cAMP-responsive element-binding protein 1 (CREB1) is associated with metastasis, tumor stage and poor outcome in gastric cancer. Oncotarget (2015) 0.93
MicroRNA-200b targets CREB1 and suppresses cell growth in human malignant glioma. Mol Cell Biochem (2013) 0.92
Modulation of the metastatic capability in B16 melanoma by cell shape. Science (1983) 0.91
MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer. Mol Cancer (2014) 0.91
HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth. Cell Rep (2015) 0.90
Mitochondrial complex I inhibitors and forced oxidative phosphorylation synergize in inducing cancer cell death. Int J Cell Biol (2013) 0.90
The multifaceted activities of AMPK in tumor progression--why the "one size fits all" definition does not fit at all? IUBMB Life (2013) 0.90
Glucose deprivation induces G2/M transition-arrest and cell death in N-GlcNAc2-modified protein-producing renal carcinoma cells. PLoS One (2014) 0.89
PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling. Oncogene (2014) 0.89
Glucose deprivation induces reticulum stress by the PERK pathway and caspase-7- and calpain-mediated caspase-12 activation. Apoptosis (2014) 0.88