Immunodynamics: a cancer immunotherapy trials network review of immune monitoring in immuno-oncology clinical trials.

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Published in J Immunother Cancer on March 15, 2016

Authors

Holbrook E Kohrt1, Paul C Tumeh2, Don Benson3, Nina Bhardwaj4, Joshua Brody5, Silvia Formenti6, Bernard A Fox7, Jerome Galon8, Carl H June9, Michael Kalos10, Ilan Kirsch11, Thomas Kleen12, Guido Kroemer13, Lewis Lanier14, Ron Levy15, H Kim Lyerly16, Holden Maecker17, Aurelien Marabelle18, Jos Melenhorst19, Jeffrey Miller20, Ignacio Melero21, Kunle Odunsi22, Karolina Palucka23, George Peoples24, Antoni Ribas25, Harlan Robins26, William Robinson27, Tito Serafini28, Paul Sondel29, Eric Vivier30, Jeff Weber31, Jedd Wolchok32, Laurence Zitvogel33, Mary L Disis34, Martin A Cheever35, Cancer Immunotherapy Trials Network (CITN)

Author Affiliations

1: Division of Oncology, Stanford Cancer Institute, Stanford University Medical Center, 269 Campus Drive, CCSR 1105, Stanford, CA 94305-5151 USA.
2: Division of Dermatology, Department of Medicine, University of California Los Angeles, Los Angeles, CA USA.
3: Division of Hematology/Oncology, Ohio State University, Columbus, OH USA.
4: Medicine, Hematology and Medical Oncology, Mount Sinai Hospital, New York, NY USA.
5: Medicine, Hematology and Medical Oncology, Mount Sinai Hospital, Ruttenberg Treatment Center, New York, NY USA.
6: Department of Radiation Oncology, New York Weill Cornell Medical Center, New York, NY USA.
7: SOM-Molecular Microbiology & Immunology Department, Laboratory of Molecular and Tumor Immunology, OHSU Cancer Institute, Portland, OR USA.
8: INSERM, Integrative Cancer Immunology Team, Cordeliers Research Center, Paris, France.
9: Perelman School of Medicine, University of Pennsylvania, Pathology and Laboratory Medicine, Philadelphia, PA USA.
10: Cancer Immunobiology, Eli Lilly & Company, New York, NY USA.
11: Translational Medicine, Adaptive Biotechnologies Corp, Seattle, WA USA.
12: Immune Monitoring, Epiontis GmbH, Berlin, Germany.
13: Faculty of Medicine, University of Paris Descartes, Paris, France.
14: Department of Microbiology and Immunology, University of California, San Francisco, CA USA.
15: Division of Oncology, Stanford School of Medicine, Stanford, CA USA.
16: Duke University School of Medicine, Durham, NC USA.
17: Human Immune Monitoring Center Shared Resource, Stanford Cancer Institute, Stanford, CA USA.
18: Léon Bérard Cancer Center, Lyon, France.
19: Product Development and Correlative Sciences, Smilow Center for Translational Research, Philadelphia, PA USA.
20: Division of Hematology, Experimental Therapeutics, University of Minnesota, Oncology and Transplantation, Minneapolis, MN USA.
21: Centro de Investigacion Medica Aplicada, Universidad de Navarra, Avda. Pamplona, Spain.
22: Center for Immunotherapy, Roswell Park Cancer Institute, Buffalo, NY USA.
23: Baylor Institute for Immunology Research, Dallas, TX USA.
24: Cancer Vaccine Development Program, Brooke Army Medical Center, Houston, TX USA.
25: Tumor Immunology Program Area, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA USA.
26: Adaptive Biotechnologies, Seattle, WA USA.
27: Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA USA.
28: Atreca, Inc, Redwood City, CA USA.
29: Cellular & Molecular Pathology Graduate Program, University of Wisconsin-Madison, Madison, WI USA.
30: Centre d'Immunologie de Marseille-Luminy, Marseille, France.
31: Moffitt Cancer Center, Tampa, FL USA.
32: Immunology Program, Memorial Sloan-Kettering Cancer Center, New York, NY USA.
33: Institut National de la Santé et Recherche Médicale, Institut GrustaveRoussy, Villejuif, France.
34: Tumor Vaccine Group, University of Washington, Seattle, WA USA.
35: Fred Hutchinson Cancer Research Center, 1100 Eastlake Ave N., E3-300, PO Box 19024, Seattle, WA 98109-1023 USA.

Associated clinical trials:

Phase I-II Study of Intratumoral Urelumab Combined With Nivolumab in Patients With Solid Tumors (INTRUST) | NCT03792724

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