Published in Cell Chem Biol on January 28, 2016
Diverse Ecological Strategies Are Encoded by Streptococcus pneumoniae Bacteriocin-Like Peptides. Genome Biol Evol (2016) 0.79
Insights into the biosynthesis of duramycin. Appl Environ Microbiol (2016) 0.78
The Enterococcal Cytolysin Synthetase Coevolves with Substrate for Stereoselective Lanthionine Synthesis. ACS Chem Biol (2016) 0.78
Towards Biocontained Cell Factories: An Evolutionarily Adapted Escherichia coli Strain Produces a New-to-nature Bioactive Lantibiotic Containing Thienopyrrole-Alanine. Sci Rep (2016) 0.76
Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes. Chem Rev (2017) 0.75
Combinatorial Lanthipeptides from a Ruminant Bacterium. Cell Chem Biol (2016) 0.75
Ribosomally synthesized and post-translationally modified peptide natural product discovery in the genomic era. Curr Opin Chem Biol (2017) 0.75
Basic local alignment search tool. J Mol Biol (1990) 659.07
Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega. Mol Syst Biol (2011) 28.61
Host-bacterial mutualism in the human intestine. Science (2005) 26.39
Evolution of mammals and their gut microbes. Science (2008) 21.40
An ecological and evolutionary perspective on human-microbe mutualism and disease. Nature (2007) 10.92
Interactions between the microbiota and the immune system. Science (2012) 10.45
Functional interactions between the gut microbiota and host metabolism. Nature (2012) 7.91
Gut microorganisms, mammalian metabolism and personalized health care. Nat Rev Microbiol (2005) 5.35
Reciprocal interactions of the intestinal microbiota and immune system. Nature (2012) 4.42
A family of bacteriocin ABC transporters carry out proteolytic processing of their substrates concomitant with export. Mol Microbiol (1995) 4.07
Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity. Science (2004) 2.83
The mode of action of the lantibiotic lacticin 3147--a complex mechanism involving specific interaction of two peptides and the cell wall precursor lipid II. Mol Microbiol (2006) 2.53
Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic. Proc Natl Acad Sci U S A (2006) 2.19
Biosynthesis, immunity, regulation, mode of action and engineering of the model lantibiotic nisin. Cell Mol Life Sci (2008) 2.18
Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria. Proc Natl Acad Sci U S A (2010) 2.18
Siderophores from neighboring organisms promote the growth of uncultured bacteria. Chem Biol (2010) 2.04
Discovery, biosynthesis, and engineering of lantipeptides. Annu Rev Biochem (2012) 2.01
Cancer and the microbiota. Science (2015) 1.97
Structure-activity relationship studies of the two-component lantibiotic haloduracin. Chem Biol (2008) 1.95
Status of the phylogenetic diversity census of ruminal microbiomes. FEMS Microbiol Ecol (2011) 1.94
Comparison of lantibiotic gene clusters and encoded proteins. Antonie Van Leeuwenhoek (1996) 1.88
Lantibiotic structures as guidelines for the design of peptides that can be modified by lantibiotic enzymes. Biochemistry (2005) 1.84
Spontaneous alpha-N-6-phosphogluconoylation of a "His tag" in Escherichia coli: the cause of extra mass of 258 or 178 Da in fusion proteins. Anal Biochem (1999) 1.80
The impact of bacterial genomics on natural product research. Angew Chem Int Ed Engl (2005) 1.70
Ruminococcin A, a new lantibiotic produced by a Ruminococcus gnavus strain isolated from human feces. Appl Environ Microbiol (2001) 1.69
Identification of a novel two-peptide lantibiotic, lichenicidin, following rational genome mining for LanM proteins. Appl Environ Microbiol (2009) 1.68
Genomics-inspired discovery of natural products. Curr Opin Chem Biol (2010) 1.62
Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity. Biochemistry (2004) 1.61
Lacticin 3147, a broad-spectrum bacteriocin which selectively dissipates the membrane potential. Appl Environ Microbiol (1998) 1.58
Production of lantipeptides in Escherichia coli. J Am Chem Soc (2010) 1.56
Interspecies interactions stimulate diversification of the Streptomyces coelicolor secreted metabolome. MBio (2013) 1.56
Lantibiotics from Geobacillus thermodenitrificans. Proc Natl Acad Sci U S A (2012) 1.53
Substrate control in stereoselective lanthionine biosynthesis. Nat Chem (2014) 1.51
Plantazolicin, a novel microcin B17/streptolysin S-like natural product from Bacillus amyloliquefaciens FZB42. J Bacteriol (2010) 1.47
Complete alanine scanning of the two-component lantibiotic lacticin 3147: generating a blueprint for rational drug design. Mol Microbiol (2006) 1.45
Sublancin is not a lantibiotic but an S-linked glycopeptide. Nat Chem Biol (2011) 1.44
The biology of lantibiotics from the lacticin 481 group is coming of age. FEMS Microbiol Rev (2006) 1.38
Diversity and strain specificity of plant cell wall degrading enzymes revealed by the draft genome of Ruminococcus flavefaciens FD-1. PLoS One (2009) 1.37
Insights into the mode of action of the two-peptide lantibiotic haloduracin. ACS Chem Biol (2009) 1.32
NMR study of mersacidin and lipid II interaction in dodecylphosphocholine micelles. Conformational changes are a key to antimicrobial activity. J Biol Chem (2003) 1.25
Heterologous expression, biosynthesis, and mutagenesis of type II lantibiotics from Bacillus licheniformis in Escherichia coli. Chem Biol (2011) 1.20
Construction of an expression system for site-directed mutagenesis of the lantibiotic mersacidin. Appl Environ Microbiol (2003) 1.20
Structural characterization of four prochlorosins: a novel class of lantipeptides produced by planktonic marine cyanobacteria. Biochemistry (2012) 1.18
Nine post-translational modifications during the biosynthesis of cinnamycin. J Am Chem Soc (2011) 1.15
Ribosomally synthesized and post-translationally modified peptide natural products: new insights into the role of leader and core peptides during biosynthesis. Chemistry (2013) 1.15
Production of the novel two-peptide lantibiotic lichenicidin by Bacillus licheniformis DSM 13. PLoS One (2009) 1.14
Chapter 21. In vitro studies of lantibiotic biosynthesis. Methods Enzymol (2009) 1.13
Isolation and characterization of a bacteriocin (Butyrivibriocin AR10) from the ruminal anaerobe Butyrivibrio fibrisolvens AR10: evidence in support of the widespread occurrence of bacteriocin-like activity among ruminal isolates of B. fibrisolvens. Appl Environ Microbiol (1997) 1.11
Requirements of the engineered leader peptide of nisin for inducing modification, export, and cleavage. Appl Environ Microbiol (2010) 1.11
An integrative view of microbiome-host interactions in inflammatory bowel diseases. Cell Host Microbe (2015) 1.11
Utilization of individual cellodextrins by three predominant ruminal cellulolytic bacteria. Appl Environ Microbiol (1996) 1.10
Biosynthesis of the antimicrobial peptide epilancin 15X and its N-terminal lactate. Chem Biol (2011) 1.10
The sequence of the enterococcal cytolysin imparts unusual lanthionine stereochemistry. Nat Chem Biol (2013) 1.09
Production of a class II two-component lantibiotic of Streptococcus pneumoniae using the class I nisin synthetic machinery and leader sequence. Antimicrob Agents Chemother (2010) 1.08
Each peptide of the two-component lantibiotic lacticin 3147 requires a separate modification enzyme for activity. Microbiology (2000) 1.08
Connecting chemotypes and phenotypes of cultured marine microbial assemblages by imaging mass spectrometry. Angew Chem Int Ed Engl (2011) 1.07
Isolation, structure elucidation, and synergistic antibacterial activity of a novel two-component lantibiotic lichenicidin from Bacillus licheniformis VK21. Biochemistry (2010) 1.07
Distribution of genes encoding the trypsin-dependent lantibiotic ruminococcin A among bacteria isolated from human fecal microbiota. Appl Environ Microbiol (2002) 1.06
The use of 16S rRNA-targeted oligonucleotide probes to study competition between ruminal fibrolytic bacteria: pure-culture studies with cellulose and alkaline peroxide-treated wheat straw. Appl Environ Microbiol (1994) 1.06
Redundancy, resilience, and host specificity of the ruminal microbiota: implications for engineering improved ruminal fermentations. Front Microbiol (2015) 1.05
The bacteriocins of ruminal bacteria and their potential as an alternative to antibiotics. J Mol Microbiol Biotechnol (2002) 1.02
Synthesis of the lantibiotic lactocin S using peptide cyclizations on solid phase. J Am Chem Soc (2010) 1.01
Maturation by LctT is required for biosynthesis of full-length lantibiotic lacticin 481. Appl Environ Microbiol (2005) 1.01
Biomass utilization by gut microbiomes. Annu Rev Microbiol (2014) 1.00
Dissection of the bridging pattern of bovicin HJ50, a lantibiotic containing a characteristic disulfide bridge. Microbiol Res (2010) 1.00
Evidence for production of a new lantibiotic (butyrivibriocin OR79A) by the ruminal anaerobe Butyrivibrio fibrisolvens OR79: characterization of the structural gene encoding butyrivibriocin OR79A. Appl Environ Microbiol (1999) 0.98
Structure and biosynthesis of carnolysin, a homologue of enterococcal cytolysin with D-amino acids. J Am Chem Soc (2014) 0.96
Ring A of nukacin ISK-1: a lipid II-binding motif for type-A(II) lantibiotic. J Am Chem Soc (2012) 0.96
Lanthionine introduction into nukacin ISK-1 prepeptide by co-expression with modification enzyme NukM in Escherichia coli. Biochem Biophys Res Commun (2005) 0.96
A price to pay for relaxed substrate specificity: a comparative kinetic analysis of the class II lanthipeptide synthetases ProcM and HalM2. J Am Chem Soc (2014) 0.96
A general method for fluorescent labeling of the N-termini of lanthipeptides and its application to visualize their cellular localization. J Am Chem Soc (2013) 0.95
Haloduracin α binds the peptidoglycan precursor lipid II with 2:1 stoichiometry. J Am Chem Soc (2011) 0.94
Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in anaerobic bacteria. BMC Genomics (2014) 0.93
Microbiota and autoimmunity: exploring new avenues. Cell Host Microbe (2015) 0.93
High divergence of the precursor peptides in combinatorial lanthipeptide biosynthesis. ACS Chem Biol (2014) 0.90
Bovicin HJ50-like lantibiotics, a novel subgroup of lantibiotics featured by an indispensable disulfide bridge. PLoS One (2014) 0.90
Heterologous production of the lantibiotic Ala(0)actagardine in Escherichia coli. Chem Commun (Camb) (2012) 0.88
Chemical communication in the gut: Effects of microbiota-generated metabolites on gastrointestinal bacterial pathogens. Anaerobe (2015) 0.86
Albusin B, a bacteriocin from the ruminal bacterium Ruminococcus albus 7 that inhibits growth of Ruminococcus flavefaciens. Appl Environ Microbiol (2004) 0.86
Novel LanT associated lantibiotic clusters identified by genome database mining. PLoS One (2014) 0.85
A unique lantibiotic, thermophilin 1277, containing a disulfide bridge and two thioether bridges. J Appl Microbiol (2009) 0.84
The glycosyltransferase involved in thurandacin biosynthesis catalyzes both O- and S-glycosylation. J Am Chem Soc (2013) 0.82
Type AII lantibiotic bovicin HJ50 with a rare disulfide bond: structure, structure-activity relationships and mode of action. Biochem J (2014) 0.79
Synergistic binding of the leader and core peptides by the lantibiotic synthetase HalM2. ACS Chem Biol (2015) 0.79
Pseudomycoicidin, a Class II Lantibiotic from Bacillus pseudomycoides. Appl Environ Microbiol (2015) 0.79
Characterization of ISRgn1, a novel insertion sequence of the IS3 family isolated from a bacteriocin-negative mutant of Ruminococcus gnavus E1. Appl Environ Microbiol (2002) 0.79
Characterization and distribution of the gene cluster encoding RumC, an anti-Clostridium perfringens bacteriocin produced in the gut. FEMS Microbiol Ecol (2011) 0.79
Ruminococcin C, a new anti-Clostridium perfringens bacteriocin produced in the gut by the commensal bacterium Ruminococcus gnavus E1. Biochimie (2011) 0.79
Distribution and Genetic Diversity of Bacteriocin Gene Clusters in Rumen Microbial Genomes. Appl Environ Microbiol (2015) 0.78