Published in Biochemistry on June 21, 2005
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep (2013) 5.38
Structure-activity relationship studies of the two-component lantibiotic haloduracin. Chem Biol (2008) 1.95
Genome mining and genetic analysis of cypemycin biosynthesis reveal an unusual class of posttranslationally modified peptides. Proc Natl Acad Sci U S A (2010) 1.52
Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by C-terminal truncation. Appl Environ Microbiol (2007) 1.46
The importance of the leader sequence for directing lanthionine formation in lacticin 481. Biochemistry (2008) 1.46
Structural Characterization and Bioactivity Analysis of the Two-Component Lantibiotic Flv System from a Ruminant Bacterium. Cell Chem Biol (2016) 1.45
Production of dehydroamino acid-containing peptides by Lactococcus lactis. Appl Environ Microbiol (2007) 1.36
The leader peptide is not required for post-translational modification by lacticin 481 synthetase. J Am Chem Soc (2007) 1.31
Dissecting structural and functional diversity of the lantibiotic mersacidin. Chem Biol (2009) 1.25
Directionality and coordination of dehydration and ring formation during biosynthesis of the lantibiotic nisin. J Biol Chem (2009) 1.21
On the substrate specificity of dehydration by lacticin 481 synthetase. J Am Chem Soc (2007) 1.16
Requirements of the engineered leader peptide of nisin for inducing modification, export, and cleavage. Appl Environ Microbiol (2010) 1.11
Production of a class II two-component lantibiotic of Streptococcus pneumoniae using the class I nisin synthetic machinery and leader sequence. Antimicrob Agents Chemother (2010) 1.08
Investigation of the substrate specificity of lacticin 481 synthetase by using nonproteinogenic amino acids. Chembiochem (2009) 1.02
Sec-mediated transport of posttranslationally dehydrated peptides in Lactococcus lactis. Appl Environ Microbiol (2006) 1.01
Rings, radicals, and regeneration: the early years of a bioorganic laboratory. J Org Chem (2006) 0.98
On the regioselectivity of thioether formation by lacticin 481 synthetase. Org Lett (2007) 0.98
Use of lantibiotic synthetases for the preparation of bioactive constrained peptides. Bioorg Med Chem Lett (2008) 0.98
Substrate recognition and specificity of the NisB protein, the lantibiotic dehydratase involved in nisin biosynthesis. J Biol Chem (2011) 0.96
A general method for fluorescent labeling of the N-termini of lanthipeptides and its application to visualize their cellular localization. J Am Chem Soc (2013) 0.95
Bioengineering of a Nisin A-producing Lactococcus lactis to create isogenic strains producing the natural variants Nisin F, Q and Z. Microb Biotechnol (2010) 0.95
Cerecidins, novel lantibiotics from Bacillus cereus with potent antimicrobial activity. Appl Environ Microbiol (2014) 0.95
Mechanistic dissection of the enzyme complexes involved in biosynthesis of lacticin 3147 and nisin. Appl Environ Microbiol (2008) 0.93
Saturation mutagenesis of lysine 12 leads to the identification of derivatives of nisin A with enhanced antimicrobial activity. PLoS One (2013) 0.92
Lacticin 481 synthetase as a general serine/threonine kinase. ACS Chem Biol (2009) 0.91
Influence of shifting positions of Ser, Thr, and Cys residues in prenisin on the efficiency of modification reactions and on the antimicrobial activities of the modified prepeptides. Appl Environ Microbiol (2008) 0.91
The length of a lantibiotic hinge region has profound influence on antimicrobial activity and host specificity. Front Microbiol (2015) 0.90
Bovicin HJ50-like lantibiotics, a novel subgroup of lantibiotics featured by an indispensable disulfide bridge. PLoS One (2014) 0.90
Distinct contributions of the nisin biosynthesis enzymes NisB and NisC and transporter NisT to prenisin production by Lactococcus lactis. Appl Environ Microbiol (2008) 0.88
In vitro selection of functional lantipeptides. J Am Chem Soc (2012) 0.88
Post-translational Modifications of Natural Antimicrobial Peptides and Strategies for Peptide Engineering. Curr Biotechnol (2012) 0.86
Intensive mutagenesis of the nisin hinge leads to the rational design of enhanced derivatives. PLoS One (2013) 0.85
Identification of distinct nisin leader peptide regions that determine interactions with the modification enzymes NisB and NisC. FEBS Open Bio (2013) 0.84
Identification of essential amino acid residues in the nisin dehydratase NisB. Front Microbiol (2015) 0.79
The C-terminus of nisin is important for the ABC transporter NisFEG to confer immunity in Lactococcus lactis. Microbiologyopen (2014) 0.79
The presence of modifiable residues in the core peptide part of precursor nisin is not crucial for precursor nisin interactions with NisB- and NisC. PLoS One (2013) 0.79
Thiostrepton Variants Containing a Contracted Quinaldic Acid Macrocycle Result from Mutagenesis of the Second Residue. ACS Chem Biol (2015) 0.78
Lantibiotic Reductase LtnJ Substrate Selectivity Assessed with a Collection of Nisin Derivatives as Substrates. Appl Environ Microbiol (2015) 0.78
Saturation mutagenesis of TsrA Ala4 unveils a highly mutable residue of thiostrepton A. ACS Chem Biol (2015) 0.78
Translocation of a thioether-bridged azurin peptide fragment via the sec pathway in Lactococcus lactis. Appl Environ Microbiol (2009) 0.77
Incorporation of tryptophan analogues into the lantibiotic nisin. Amino Acids (2016) 0.76
Prospects of In vivo Incorporation of Non-canonical Amino Acids for the Chemical Diversification of Antimicrobial Peptides. Front Microbiol (2017) 0.75
Stoichiometry and structure of a lantibiotic maturation complex. Sci Rep (2017) 0.75
Bacterial display and screening of posttranslationally thioether-stabilized peptides. Appl Environ Microbiol (2011) 0.75
Potentiating the Activity of Nisin against Escherichia coli. Front Cell Dev Biol (2016) 0.75
Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes. Chem Rev (2017) 0.75
Complete genome sequence of Lactobacillus plantarum WCFS1. Proc Natl Acad Sci U S A (2003) 8.40
Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88. Nat Biotechnol (2007) 6.21
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep (2013) 5.38
Bistability, epigenetics, and bet-hedging in bacteria. Annu Rev Microbiol (2008) 4.74
Phenotypic variation in bacteria: the role of feedback regulation. Nat Rev Microbiol (2006) 3.73
Complete genome sequence of the prototype lactic acid bacterium Lactococcus lactis subsp. cremoris MG1363. J Bacteriol (2007) 3.43
Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis. Science (2006) 3.29
BAGEL3: Automated identification of genes encoding bacteriocins and (non-)bactericidal posttranslationally modified peptides. Nucleic Acids Res (2013) 3.23
Projector 2: contig mapping for efficient gap-closure of prokaryotic genome sequence assemblies. Nucleic Acids Res (2005) 3.22
Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum. Nat Biotechnol (2008) 3.16
An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II. Science (2006) 3.05
LysM, a widely distributed protein motif for binding to (peptido)glycans. Mol Microbiol (2008) 2.98
Bet-hedging and epigenetic inheritance in bacterial cell development. Proc Natl Acad Sci U S A (2008) 2.88
Proteomics of protein secretion by Bacillus subtilis: separating the "secrets" of the secretome. Microbiol Mol Biol Rev (2004) 2.67
Subcellular sites for bacterial protein export. Mol Microbiol (2004) 2.50
Stripping Bacillus: ComK auto-stimulation is responsible for the bistable response in competence development. Mol Microbiol (2005) 2.35
Controlling competence in Bacillus subtilis: shared use of regulators. Microbiology (2003) 2.30
Phosphatases modulate the bistable sporulation gene expression pattern in Bacillus subtilis. Mol Microbiol (2005) 2.29
Cell wall attachment of a widely distributed peptidoglycan binding domain is hindered by cell wall constituents. J Biol Chem (2003) 2.28
The Lactococcus lactis CodY regulon: identification of a conserved cis-regulatory element. J Biol Chem (2005) 2.11
BAGEL2: mining for bacteriocins in genomic data. Nucleic Acids Res (2010) 2.08
The Sec translocase. Biochim Biophys Acta (2010) 2.04
Sec- and Tat-mediated protein secretion across the bacterial cytoplasmic membrane--distinct translocases and mechanisms. Biochim Biophys Acta (2007) 2.03
A generally applicable validation scheme for the assessment of factors involved in reproducibility and quality of DNA-microarray data. BMC Genomics (2005) 1.96
Genome2D: a visualization tool for the rapid analysis of bacterial transcriptome data. Genome Biol (2004) 1.93
MicroPreP: a cDNA microarray data pre-processing framework. Appl Bioinformatics (2003) 1.86
Improving the predictive value of the competence transcription factor (ComK) binding site in Bacillus subtilis using a genomic approach. Nucleic Acids Res (2002) 1.84
The relative value of operon predictions. Brief Bioinform (2008) 1.81
The protein-conducting channel SecYEG. Biochim Biophys Acta (2004) 1.72
UV-inducible DNA exchange in hyperthermophilic archaea mediated by type IV pili. Mol Microbiol (2011) 1.71
Time-resolved determination of the CcpA regulon of Lactococcus lactis subsp. cremoris MG1363. J Bacteriol (2006) 1.69
Post-translational modification of therapeutic peptides by NisB, the dehydratase of the lantibiotic nisin. Biochemistry (2005) 1.68
FIVA: Functional Information Viewer and Analyzer extracting biological knowledge from transcriptome data of prokaryotes. Bioinformatics (2007) 1.65
SecDFyajC forms a heterotetrameric complex with YidC. Mol Microbiol (2002) 1.64
CodY of Streptococcus pneumoniae: link between nutritional gene regulation and colonization. J Bacteriol (2007) 1.64
BAGEL: a web-based bacteriocin genome mining tool. Nucleic Acids Res (2006) 1.64
The iturin and fengycin families of lipopeptides are key factors in antagonism of Bacillus subtilis toward Podosphaera fusca. Mol Plant Microbe Interact (2007) 1.61
Elucidating the native architecture of the YidC: ribosome complex. J Mol Biol (2013) 1.61
Transient heterogeneity in extracellular protease production by Bacillus subtilis. Mol Syst Biol (2008) 1.60
Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus: nucleotide-free and nucleotide-bound conformations. J Mol Biol (2003) 1.59
F1F0 ATP synthase subunit c is a substrate of the novel YidC pathway for membrane protein biogenesis. J Cell Biol (2004) 1.58
Archaeal homolog of bacterial type IV prepilin signal peptidases with broad substrate specificity. J Bacteriol (2003) 1.56
The 2008 update of the Aspergillus nidulans genome annotation: a community effort. Fungal Genet Biol (2008) 1.56
Effects of phosphorelay perturbations on architecture, sporulation, and spore resistance in biofilms of Bacillus subtilis. J Bacteriol (2006) 1.56
UniFrag and GenomePrimer: selection of primers for genome-wide production of unique amplicons. Bioinformatics (2003) 1.55
Genome engineering reveals large dispensable regions in Bacillus subtilis. Mol Biol Evol (2003) 1.55
Novel surface display system for proteins on non-genetically modified gram-positive bacteria. Appl Environ Microbiol (2006) 1.53
Identification of diverse archaeal proteins with class III signal peptides cleaved by distinct archaeal prepilin peptidases. J Bacteriol (2006) 1.52
SpxB regulates O-acetylation-dependent resistance of Lactococcus lactis peptidoglycan to hydrolysis. J Biol Chem (2007) 1.51
Regulation of archaella expression by the FHA and von Willebrand domain-containing proteins ArnA and ArnB in Sulfolobus acidocaldarius. Mol Microbiol (2012) 1.51
Regulation of glutamine and glutamate metabolism by GlnR and GlnA in Streptococcus pneumoniae. J Biol Chem (2006) 1.50
Autolysis of Lactococcus lactis is increased upon D-alanine depletion of peptidoglycan and lipoteichoic acids. J Bacteriol (2005) 1.49
The novel transcriptional regulator SczA mediates protection against Zn2+ stress by activation of the Zn2+-resistance gene czcD in Streptococcus pneumoniae. Mol Microbiol (2007) 1.49
The Rok protein of Bacillus subtilis represses genes for cell surface and extracellular functions. J Bacteriol (2005) 1.49
A novel class of heat and secretion stress-responsive genes is controlled by the autoregulated CssRS two-component system of Bacillus subtilis. J Bacteriol (2002) 1.48
The lateral gate of SecYEG opens during protein translocation. J Biol Chem (2009) 1.48
The cell membrane plays a crucial role in survival of bacteria and archaea in extreme environments. Antonie Van Leeuwenhoek (2002) 1.47
PePPER: a webserver for prediction of prokaryote promoter elements and regulons. BMC Genomics (2012) 1.47
NisT, the transporter of the lantibiotic nisin, can transport fully modified, dehydrated, and unmodified prenisin and fusions of the leader peptide with non-lantibiotic peptides. J Biol Chem (2004) 1.47
Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by C-terminal truncation. Appl Environ Microbiol (2007) 1.46
The cop operon is required for copper homeostasis and contributes to virulence in Streptococcus pneumoniae. Mol Microbiol (2011) 1.46
Distribution and physiology of ABC-type transporters contributing to multidrug resistance in bacteria. Microbiol Mol Biol Rev (2007) 1.46
AcmA of Lactococcus lactis is an N-acetylglucosaminidase with an optimal number of LysM domains for proper functioning. FEBS J (2005) 1.45
To have neighbour's fare: extending the molecular toolbox for Streptococcus pneumoniae. Microbiology (2006) 1.45
Temporal separation of distinct differentiation pathways by a dual specificity Rap-Phr system in Bacillus subtilis. Mol Microbiol (2007) 1.44
Overview on sugar metabolism and its control in Lactococcus lactis - the input from in vivo NMR. FEMS Microbiol Rev (2005) 1.44
Live Cell Imaging of Bacillus subtilis and Streptococcus pneumoniae using Automated Time-lapse Microscopy. J Vis Exp (2011) 1.43
Copper stress affects iron homeostasis by destabilizing iron-sulfur cluster formation in Bacillus subtilis. J Bacteriol (2010) 1.40
GTP hydrolysis of cell division protein FtsZ: evidence that the active site is formed by the association of monomers. Biochemistry (2002) 1.39
Molecular Genetics Information System (MOLGENIS): alternatives in developing local experimental genomics databases. Bioinformatics (2004) 1.38
Projector: automatic contig mapping for gap closure purposes. Nucleic Acids Res (2003) 1.38
Production of dehydroamino acid-containing peptides by Lactococcus lactis. Appl Environ Microbiol (2007) 1.36
UV-inducible cellular aggregation of the hyperthermophilic archaeon Sulfolobus solfataricus is mediated by pili formation. Mol Microbiol (2008) 1.35
Proteomic analysis of secreted membrane vesicles of archaeal Sulfolobus species reveals the presence of endosome sorting complex components. Extremophiles (2008) 1.34
LmrCD is a major multidrug resistance transporter in Lactococcus lactis. Mol Microbiol (2006) 1.34
Expanding and understanding the genetic toolbox of the hyperthermophilic genus Sulfolobus. Biochem Soc Trans (2009) 1.32
Direct observation of chaperone-induced changes in a protein folding pathway. Science (2007) 1.32
Probing direct interactions between CodY and the oppD promoter of Lactococcus lactis. J Bacteriol (2005) 1.29
Cell envelope stress induced by the bacteriocin Lcn972 is sensed by the Lactococcal two-component system CesSR. Mol Microbiol (2007) 1.28
Formation of the productive ATP-Mg2+-bound dimer of GlcV, an ABC-ATPase from Sulfolobus solfataricus. J Mol Biol (2003) 1.28
ArgR and AhrC are both required for regulation of arginine metabolism in Lactococcus lactis. J Bacteriol (2004) 1.27
Identification of a system required for the functional surface localization of sugar binding proteins with class III signal peptides in Sulfolobus solfataricus. Mol Microbiol (2007) 1.27
Angiotensin-(1-7) with thioether bridge: an angiotensin-converting enzyme-resistant, potent angiotensin-(1-7) analog. J Pharmacol Exp Ther (2008) 1.26