NBS1 and multiple regulations of DNA damage response.

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature (2005) 7.45

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response. Cell (1998) 6.58

The ATM protein kinase: regulating the cellular response to genotoxic stress, and more. Nat Rev Mol Cell Biol (2013) 5.33

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome. Cell (1998) 4.72

The many interfaces of Mre11. Cell (1998) 4.14

Primary microcephaly: do all roads lead to Rome? Trends Genet (2009) 3.60

Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway. Genes Dev (2012) 3.42

A new chromosomal instability disorder: the Nijmegen breakage syndrome. Acta Paediatr Scand (1981) 2.16

Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Mol Cell (2011) 2.16

Regulation of homologous recombination by RNF20-dependent H2B ubiquitination. Mol Cell (2011) 2.00

Interaction of FANCD2 and NBS1 in the DNA damage response. Nat Cell Biol (2002) 1.96

Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells. Nature (2002) 1.89

Chk2 activation dependence on Nbs1 after DNA damage. Mol Cell Biol (2001) 1.85

Autosomal Recessive Primary Microcephaly (MCPH): clinical manifestations, genetic heterogeneity and mutation continuum. Orphanet J Rare Dis (2011) 1.78

KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response. Nat Struct Mol Biol (2011) 1.77

Nijmegen breakage syndrome gene, NBS1, and molecular links to factors for genome stability. Oncogene (2002) 1.77

Positional cloning of the gene for Nijmegen breakage syndrome. Nat Genet (1998) 1.73

The forkhead-associated domain of NBS1 is essential for nuclear foci formation after irradiation but not essential for hRAD50[middle dot]hMRE11[middle dot]NBS1 complex DNA repair activity. J Biol Chem (2001) 1.43

NBS1 and its functional role in the DNA damage response. DNA Repair (Amst) (2004) 1.30

Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1. Cell Rep (2013) 1.19

Human Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass. Proc Natl Acad Sci U S A (2014) 1.18

CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination. EMBO Rep (2012) 1.07

Genetic mapping using microcell-mediated chromosome transfer suggests a locus for Nijmegen breakage syndrome at chromosome 8q21-24. Am J Hum Genet (1997) 1.04

Homologous recombination repair is regulated by domains at the N- and C-terminus of NBS1 and is dissociated with ATM functions. Oncogene (2007) 1.04

TopBP1 associates with NBS1 and is involved in homologous recombination repair. Biochem Biophys Res Commun (2007) 1.03

A review of forty-five years study of Hiroshima and Nagasaki atomic bomb survivors. Brain damage among the prenatally exposed. J Radiat Res (1991) 1.01

NBS1 recruits RAD18 via a RAD6-like domain and regulates Pol η-dependent translesion DNA synthesis. Mol Cell (2011) 0.98

The gene for Nijmegen breakage syndrome (V2) is not located on chromosome 11. Am J Hum Genet (1996) 0.98

Histone chaperone FACT regulates homologous recombination by chromatin remodeling through interaction with RNF20. J Cell Sci (2013) 0.93

First case of aplastic anemia in a Japanese child with a homozygous missense mutation in the NBS1 gene (I171V) associated with genomic instability. Hum Genet (2004) 0.92

Lack of correlation between radiosensitivity and inhibition of DNA synthesis in hybrids (A-T x HeLa). Int J Radiat Biol (1989) 0.90

Opposing ISWI- and CHD-class chromatin remodeling activities orchestrate heterochromatic DNA repair. J Cell Biol (2014) 0.90

Symmetry and asymmetry of the RING-RING dimer of Rad18. J Mol Biol (2011) 0.89

Nijmegen breakage syndrome and functions of the responsible protein, NBS1. Genome Dyn (2006) 0.88

Mild Nijmegen breakage syndrome phenotype due to alternative splicing. Hum Mol Genet (2006) 0.86

Inactivation of the Nijmegen breakage syndrome gene leads to excess centrosome duplication via the ATR/BRCA1 pathway. Cancer Res (2009) 0.82

Differential role of repair proteins, BRCA1/NBS1 and Ku70/DNA-PKcs, in radiation-induced centrosome overduplication. Cancer Sci (2010) 0.81

High LET radiation amplifies centrosome overduplication through a pathway of γ-tubulin monoubiquitination. Int J Radiat Oncol Biol Phys (2013) 0.80

Impaired removal of DNA interstrand cross-link in Nijmegen breakage syndrome and Fanconi anemia, but not in BRCA-defective group. Cancer Sci (2008) 0.79

Functional Role of NBS1 in Radiation Damage Response and Translesion DNA Synthesis. Biomolecules (2015) 0.79

Fertility defects revealing germline biallelic nonsense NBN mutations. Hum Mutat (2009) 0.78

Sequence analysis of an 800-kb genomic DNA region on chromosome 8q21 that contains the Nijmegen breakage syndrome gene, NBS1. Genomics (1999) 0.78

CBP-93872 inhibits NBS1-mediated ATR activation, abrogating maintenance of the DNA double-strand break-specific G2 checkpoint. Cancer Res (2014) 0.78

RNF20-SNF2H Pathway of Chromatin Relaxation in DNA Double-Strand Break Repair. Genes (Basel) (2015) 0.77

Directed Alternative Splicing in Nijmegen Breakage Syndrome: Proof of Principle Concerning Its Therapeutical Application. Mol Ther (2015) 0.77