Published in J Biol Chem on January 05, 2001
Requirement of the MRN complex for ATM activation by DNA damage. EMBO J (2003) 6.23
ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. Mol Cell Biol (2005) 3.25
Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin. J Cell Biol (2008) 2.18
Chk2 activation dependence on Nbs1 after DNA damage. Mol Cell Biol (2001) 1.85
MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks. Proc Natl Acad Sci U S A (2008) 1.63
Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites. J Cell Biol (2009) 1.55
The fission yeast Rad32 (Mre11)-Rad50-Nbs1 complex is required for the S-phase DNA damage checkpoint. Mol Cell Biol (2003) 1.45
Distinct domains in Nbs1 regulate irradiation-induced checkpoints and apoptosis. J Exp Med (2007) 1.32
The multiple roles of the Mre11 complex for meiotic recombination. Chromosome Res (2007) 1.31
Active role for nibrin in the kinetics of atm activation. Mol Cell Biol (2006) 1.27
Functional analysis of FHA and BRCT domains of NBS1 in chromatin association and DNA damage responses. Nucleic Acids Res (2002) 1.27
Mutations of the Yku80 C terminus and Xrs2 FHA domain specifically block yeast nonhomologous end joining. Mol Cell Biol (2005) 1.18
MRE11 complex links RECQ5 helicase to sites of DNA damage. Nucleic Acids Res (2009) 1.11
Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenance. Mol Cell Biol (2003) 1.09
Isolation and characterization of novel xrs2 mutations in Saccharomyces cerevisiae. Genetics (2005) 1.08
MRN and the race to the break. Chromosoma (2009) 1.04
Xrs2p regulates Mre11p translocation to the nucleus and plays a role in telomere elongation and meiotic recombination. Mol Biol Cell (2004) 0.99
Repair of gaps opposite lesions by homologous recombination in mammalian cells. Nucleic Acids Res (2009) 0.95
Nbs1-dependent binding of Mre11 to adenovirus E4 mutant viral DNA is important for inhibiting DNA replication. Virology (2008) 0.93
A point mutation in the Aspergillus nidulans sonBNup98 nuclear pore complex gene causes conditional DNA damage sensitivity. Genetics (2006) 0.91
ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance. Cancer Res (2008) 0.91
The Nijmegen breakage syndrome gene and its role in genome stability. Chromosoma (2004) 0.89
The role of NBS1 in the modulation of PIKK family proteins ATM and ATR in the cellular response to DNA damage. Cancer Lett (2006) 0.89
WRN participates in translesion synthesis pathway through interaction with NBS1. Mech Ageing Dev (2010) 0.89
Analysis of DNA double-strand break response and chromatin structure in mitosis using laser microirradiation. Nucleic Acids Res (2010) 0.88
Coprinus cinereus rad50 mutants reveal an essential structural role for Rad50 in axial element and synaptonemal complex formation, homolog pairing and meiotic recombination. Genetics (2008) 0.88
Translesion DNA synthesis-assisted non-homologous end-joining of complex double-strand breaks prevents loss of DNA sequences in mammalian cells. Nucleic Acids Res (2009) 0.87
A mutation in the FHA domain of Coprinus cinereus Nbs1 Leads to Spo11-independent meiotic recombination and chromosome segregation. G3 (Bethesda) (2013) 0.79
Functional Role of NBS1 in Radiation Damage Response and Translesion DNA Synthesis. Biomolecules (2015) 0.79
Structural studies of DNA end detection and resection in homologous recombination. Cold Spring Harb Perspect Biol (2014) 0.78
MUC1-C Oncoprotein Interacts Directly with ATM and Promotes the DNA Damage Response to Ionizing Radiation. Genes Cancer (2010) 0.78
The MRX Complex Ensures NHEJ Fidelity through Multiple Pathways Including Xrs2-FHA-Dependent Tel1 Activation. PLoS Genet (2016) 0.77
A multistep genomic screen identifies new genes required for repair of DNA double-strand breaks in Saccharomyces cerevisiae. BMC Genomics (2013) 0.77
p16 Gene transfer increases cell killing with abnormal nucleation after ionising radiation in glioma cells. Br J Cancer (2003) 0.77
Mutations in the FHA-domain of ectopically expressed NBS1 lead to radiosensitization and to no increase in somatic mutation rates via a partial suppression of homologous recombination. J Radiat Res (2014) 0.75
NBS1 and multiple regulations of DNA damage response. J Radiat Res (2016) 0.75
Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling. Sci Rep (2017) 0.75
Molecular nature of the drug-resistance factors of the Enterobacteriaceae. J Mol Biol (1966) 6.11
Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin. Proc Natl Acad Sci U S A (1981) 4.50
Expression of the CD34 gene in vascular endothelial cells. Blood (1990) 4.41
Transcriptional sequencing: A method for DNA sequencing using RNA polymerase. Proc Natl Acad Sci U S A (1998) 3.78
Array-based genomic resequencing of human leukemia. Oncogene (2010) 3.77
P53 expression in breast cancer. Int J Cancer (1988) 3.51
An international outbreak of Salmonella infections caused by alfalfa sprouts grown from contaminated seeds. J Infect Dis (1997) 3.39
virG, a plasmid-coded virulence gene of Shigella flexneri: identification of the virG protein and determination of the complete coding sequence. J Bacteriol (1989) 3.31
Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation. EMBO J (1999) 3.22
Cinemicrographic study of tissue cell cultures infected with Shigella flexneri. Jpn J Med Sci Biol (1968) 3.12
Results of routine restaurant inspections can predict outbreaks of foodborne illness: the Seattle-King County experience. Am J Public Health (1989) 3.09
Eight genes in region 5 that form an operon are essential for invasion of epithelial cells by Shigella flexneri 2a. J Bacteriol (1993) 2.82
A dual transcriptional activation system for the 230 kb plasmid genes coding for virulence-associated antigens of Shigella flexneri. Mol Microbiol (1989) 2.81
Definitive chemoradiotherapy for T4 and/or M1 lymph node squamous cell carcinoma of the esophagus. J Clin Oncol (1999) 2.77
Functional organization and nucleotide sequence of virulence Region-2 on the large virulence plasmid in Shigella flexneri 2a. Mol Microbiol (1989) 2.68
Moxalactam (6059-S), a novel 1-oxa-beta-lactam with an expanded antibacterial spectrum: laboratory evaluation. Antimicrob Agents Chemother (1980) 2.59
An outbreak of Escherichia coli O157:H7 infection from unpasteurized commercial apple juice. Ann Intern Med (1999) 2.56
bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia. Blood (1993) 2.45
Occurrence of N-nonsubstituted glucosamine residues in peptidoglycan of lysozyme-resistant cell walls from Bacillus cereus. J Biol Chem (1972) 2.45
vasa is required for GURKEN accumulation in the oocyte, and is involved in oocyte differentiation and germline cyst development. Development (1998) 2.44
Quantitative measurements of proton motive force and motility in Bacillus subtilis. J Bacteriol (1980) 2.38
Maternal Pumilio acts together with Nanos in germline development in Drosophila embryos. Nat Cell Biol (1999) 2.35
The human amygdala plays an important role in gaze monitoring. A PET study. Brain (1999) 2.33
Identification of Shigella sonnei form I plasmid genes necessary for cell invasion and their conservation among Shigella species and enteroinvasive Escherichia coli. Infect Immun (1986) 2.14
Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3. J Biol Chem (1999) 2.09
Hospitalization in an urban homeless population: the Honolulu Urban Homeless Project. Ann Intern Med (1992) 2.04
Regio- and enantiofacial selectivity of epoxyeicosatrienoic acid hydration by cytosolic epoxide hydrolase. J Biol Chem (1993) 2.03
Occlusive thromboaortopathy (Takayasu's disease) and pregnancy. Clinical course and management of 33 pregnancies and deliveries. Am J Cardiol (1982) 2.00
Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98. Cell Death Dis (2010) 1.98
Calcitonin gene-related peptide receptor antagonist human CGRP-(8-37). Am J Physiol (1989) 1.97
Culture of human leukemia cells. Cancer (1966) 1.94
Elastofibroma in Okinawa. A clinicopathologic study of 170 cases. Cancer (1982) 1.94
Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells. Development (1994) 1.87
Efficacy of stool examination for detection of Strongyloides infection. Am J Trop Med Hyg (1995) 1.86
Association between cisplatin resistance and mutation of p53 gene and reduced bax expression in ovarian carcinoma cell systems. Cancer Res (1996) 1.85
Chk2 activation dependence on Nbs1 after DNA damage. Mol Cell Biol (2001) 1.85
Nucleotide-induced stable complex formation by HIV-1 reverse transcriptase. Biochemistry (1997) 1.82
Leptin facilitates learning and memory performance and enhances hippocampal CA1 long-term potentiation and CaMK II phosphorylation in rats. Peptides (2006) 1.80
The absence of a surface protease, OmpT, determines the intercellular spreading ability of Shigella: the relationship between the ompT and kcpA loci. Mol Microbiol (1993) 1.79
Effect of penicillin on cell wall mucopeptide synthesis in a Escherichia coli particulate system. Biochem Biophys Res Commun (1966) 1.79
The number of lymph node metastases influences survival in esophageal cancer. J Surg Oncol (1998) 1.78
A cDNA clone closely associated with non-A, non-B hepatitis. Nucleic Acids Res (1990) 1.76
The role of video-assisted thoracic surgery for the treatment of lung cancer: lung lobectomy by thoracoscopy versus the standard thoracotomy approach. Int Surg (2000) 1.76
Effect of fluoride concentration and pH on corrosion behavior of titanium for dental use. J Dent Res (1999) 1.75
Elasticity mapping of living fibroblasts by AFM and immunofluorescence observation of the cytoskeleton. Ultramicroscopy (2000) 1.74
Positional cloning of the gene for Nijmegen breakage syndrome. Nat Genet (1998) 1.73
Large plasmids associated with virulence in Shigella species have a common function necessary for epithelial cell penetration. Infect Immun (1985) 1.73
VASA mediates translation through interaction with a Drosophila yIF2 homolog. Mol Cell (2000) 1.72
Gestational thyrotoxicosis and hyperemesis gravidarum: possible role of hCG with higher stimulating activity. Clin Endocrinol (Oxf) (1993) 1.71
Occurrence of glucosamine residues with free amino groups in cell wall peptidoglycan from bacilli as a factor responsible for resistance to lysozyme. J Bacteriol (1973) 1.71
Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax. J Biol Chem (2001) 1.70
Genes encoding pseudo-response regulators: insight into His-to-Asp phosphorelay and circadian rhythm in Arabidopsis thaliana. Plant Cell Physiol (2000) 1.69
Positional cloning of the rice Rf-1 gene, a restorer of BT-type cytoplasmic male sterility that encodes a mitochondria-targeting PPR protein. Theor Appl Genet (2004) 1.68
Adaptive rundown of excitatory post-synaptic potentials at synapses between hair cells and eight nerve fibres in the goldfish. J Physiol (1978) 1.66
Compilation and characterization of Arabidopsis thaliana response regulators implicated in His-Asp phosphorelay signal transduction. Plant Cell Physiol (1999) 1.65
Response regulators implicated in His-to-Asp phosphotransfer signaling in Arabidopsis. Proc Natl Acad Sci U S A (1998) 1.65
Aging reactions in a low gold, white dental alloy. J Dent Res (1982) 1.64
Inhibition by simvastatin, but not pravastatin, of glucose-induced cytosolic Ca2+ signalling and insulin secretion due to blockade of L-type Ca2+ channels in rat islet beta-cells. Br J Pharmacol (1999) 1.64
Enzymatic synthesis of cell wall mucopeptide in a particulate preparation of Escherichia coli. Biochem Biophys Res Commun (1966) 1.62
Pathogenic properties of "enteropathogenic" Escherichia coli from diarrheal children and adults. Jpn J Med Sci Biol (1968) 1.62
Development of a digital image database for chest radiographs with and without a lung nodule: receiver operating characteristic analysis of radiologists' detection of pulmonary nodules. AJR Am J Roentgenol (2000) 1.61
Isolation of human haematopoietic progenitor cells using monoclonal antibodies. Nature (1980) 1.57
Cloning, sequencing, and expression of thermophilic Bacillus sp. strain TB-90 urease gene complex in Escherichia coli. J Bacteriol (1994) 1.57
Churg-Strauss syndrome after corticosteroid withdrawal in an asthmatic patient treated with pranlukast. J Allergy Clin Immunol (1999) 1.57
Left ventricular ejection performance, wall stress, and contractile state in aortic regurgitation before and after aortic valve replacement. Circulation (1990) 1.56
Mechanism for increase of gastrin release by secretin in Zollinger-Ellison syndrome. Gastroenterology (1989) 1.56
Cloning of regions required for contact hemolysis and entry into LLC-MK2 cells from Shigella sonnei form I plasmid: virF is a positive regulator gene for these phenotypes. Infect Immun (1989) 1.55
A mutation in the ceruloplasmin gene is associated with systemic hemosiderosis in humans. Nat Genet (1995) 1.54
Active remodeling of the coronary arterial lesions in the late phase of Kawasaki disease: immunohistochemical study. Circulation (2000) 1.54
Virulence-associated chromosomal loci of Shigella flexneri identified by random Tn5 insertion mutagenesis. Mol Microbiol (1991) 1.54
Ursodeoxycholic acid inhibits eosinophil degranulation in patients with primary biliary cirrhosis. Hepatology (1999) 1.54
p53 activity and chemotherapy. Nat Med (1996) 1.53
Claudin-1 contributes to the epithelial barrier function in MDCK cells. Eur J Cell Biol (1999) 1.53
Injection of a recombinant AAV serotype 2 into canine skeletal muscles evokes strong immune responses against transgene products. Gene Ther (2007) 1.52
Functional delineation of the human occipito-temporal areas related to face and scene processing. A PET study. Brain (2000) 1.52
A highly sensitive method for measurement of myosin ATPase activity by reversed-phase high-performance liquid chromatography. Anal Biochem (2001) 1.52
Isolation of a cDNA representing the Fanconi anemia complementation group E gene. Am J Hum Genet (2000) 1.51
Mizoribine oral pulse therapy for patients with disease flare of lupus nephritis. Clin Nephrol (2003) 1.51
Acute lymphoblastic leukaemia associated antigen. IV. Expression on non-leukaemic 'lymphoid' cells. Leuk Res (1980) 1.50
Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif. Oncogene (1997) 1.50
Molecular cloning and heterogeneity of the human hepatitis C virus (HCV) genome. J Hepatol (1993) 1.50
Diagnostic hand anomalies in Smith-Magenis syndrome: four new patients with del (17)(p11.2p11.2) Am J Med Genet (1991) 1.48
Evaluation of right ventricular function by regional wall motion analysis in patients after correction of tetralogy of Fallot. Comparison of transventricular and nontransventricular repairs. J Thorac Cardiovasc Surg (1992) 1.48
Obliterative bronchiolitis after lung and heart-lung transplantation. An analysis of risk factors and management. J Thorac Cardiovasc Surg (1995) 1.48
Geometry of the flagellar motor in the cytoplasmic membrane of Salmonella typhimurium as determined by stereo-photogrammetry of quick-freeze deep-etch replica images. J Mol Biol (1996) 1.47
A collaborative study for the evaluation of lectin-reactive alpha-fetoproteins in early detection of hepatocellular carcinoma. Cancer Res (1993) 1.47
In vitro synthesis and posttranslational uptake of cytochrome c into isolated mitochondria: role of a specific addressing signal in the apocytochrome. Proc Natl Acad Sci U S A (1981) 1.47
The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control. Proc Natl Acad Sci U S A (1999) 1.47
vacC, a virulence-associated chromosomal locus of Shigella flexneri, is homologous to tgt, a gene encoding tRNA-guanine transglycosylase (Tgt) of Escherichia coli K-12. J Bacteriol (1994) 1.45
Tyrosine phosphorylation in human neutrophil. Biochem Biophys Res Commun (1989) 1.45
Identification of a novel virulence gene, virA, on the large plasmid of Shigella, involved in invasion and intercellular spreading. Mol Microbiol (1995) 1.44
Simple procedure of DNA isolation from human serum. Nucleic Acids Res (1991) 1.44
Delayed post-prandial lipid metabolism in subjects with intra-abdominal visceral fat accumulation. Eur J Clin Invest (1999) 1.44
Sea-surface temperature from coral skeletal strontium/calcium ratios. Science (1992) 1.44
Use of lipophilic cation-permeable mutants for measurement of transmembrane electrical potential in metabolizing cells of Escherichia coli. J Bacteriol (1981) 1.43
Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer. Oncogene (1999) 1.43