Published in J Cell Biol on August 01, 1993
Evidence for budding of human immunodeficiency virus type 1 selectively from glycolipid-enriched membrane lipid rafts. J Virol (2000) 6.47
Regulated internalization of caveolae. J Cell Biol (1994) 5.77
Interactions between saturated acyl chains confer detergent resistance on lipids and glycosylphosphatidylinositol (GPI)-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behavior. Proc Natl Acad Sci U S A (1994) 5.61
Properties of lipid microdomains in a muscle cell membrane visualized by single molecule microscopy. EMBO J (2000) 5.54
Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease. J Cell Biol (1994) 5.29
Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains. J Cell Biol (1998) 4.94
Caveolins, liquid-ordered domains, and signal transduction. Mol Cell Biol (1999) 4.70
Distribution of a glycosylphosphatidylinositol-anchored protein at the apical surface of MDCK cells examined at a resolution of <100 A using imaging fluorescence resonance energy transfer. J Cell Biol (1998) 3.92
A detergent-free method for purifying caveolae membrane from tissue culture cells. Proc Natl Acad Sci U S A (1995) 3.84
Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling. Proc Natl Acad Sci U S A (1996) 3.83
Caveolae: where incoming and outgoing messengers meet. Proc Natl Acad Sci U S A (1993) 3.53
Lipid rafts: heterogeneity on the high seas. Biochem J (2004) 3.46
High-resolution FRET microscopy of cholera toxin B-subunit and GPI-anchored proteins in cell plasma membranes. Mol Biol Cell (2000) 3.37
GPI-anchored influenza hemagglutinin induces hemifusion to both red blood cell and planar bilayer membranes. J Cell Biol (1995) 3.34
Bound simian virus 40 translocates to caveolin-enriched membrane domains, and its entry is inhibited by drugs that selectively disrupt caveolae. Mol Biol Cell (1996) 3.23
Purification and characterization of smooth muscle cell caveolae. J Cell Biol (1994) 3.18
Oligomeric structure of caveolin: implications for caveolae membrane organization. Proc Natl Acad Sci U S A (1995) 3.13
Cysteine3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae. J Cell Biol (1994) 3.12
VIP21-caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro. Mol Biol Cell (1995) 3.05
Reduction of caveolin and caveolae in oncogenically transformed cells. Proc Natl Acad Sci U S A (1995) 3.03
Caveolin moves from caveolae to the Golgi apparatus in response to cholesterol oxidation. J Cell Biol (1994) 3.03
Compartmentalized IgE receptor-mediated signal transduction in living cells. J Cell Biol (1997) 2.91
Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains. EMBO J (1998) 2.83
Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains. Proc Natl Acad Sci U S A (1996) 2.79
Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment. Mol Biol Cell (1995) 2.74
Vascular endothelial growth factor induces endothelial fenestrations in vitro. J Cell Biol (1998) 2.71
Signals determining protein tyrosine kinase and glycosyl-phosphatidylinositol-anchored protein targeting to a glycolipid-enriched membrane fraction. Mol Cell Biol (1994) 2.70
Induction of caveolin during adipogenesis and association of GLUT4 with caveolin-rich vesicles. J Cell Biol (1994) 2.69
Identification, sequence, and expression of caveolin-2 defines a caveolin gene family. Proc Natl Acad Sci U S A (1996) 2.68
Decay-accelerating factor (CD55), a glycosylphosphatidylinositol-anchored complement regulatory protein, is a receptor for several echoviruses. Proc Natl Acad Sci U S A (1994) 2.57
Glycolipid-anchored proteins in neuroblastoma cells form detergent-resistant complexes without caveolin. J Cell Biol (1995) 2.46
The glycosynapse. Proc Natl Acad Sci U S A (2002) 2.46
Hierarchy of mechanisms involved in generating Na/K-ATPase polarity in MDCK epithelial cells. J Cell Biol (1995) 2.45
Caveolin-1 and -2 in the exocytic pathway of MDCK cells. J Cell Biol (1998) 2.36
Fc epsilon RI-mediated recruitment of p53/56lyn to detergent-resistant membrane domains accompanies cellular signaling. Proc Natl Acad Sci U S A (1995) 2.30
The caveolin proteins. Genome Biol (2004) 2.23
Coxsackieviruses B1, B3, and B5 use decay accelerating factor as a receptor for cell attachment. J Virol (1995) 2.20
Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains. J Cell Biol (1996) 2.19
Assembly and trafficking of caveolar domains in the cell: caveolae as stable, cargo-triggered, vesicular transporters. J Cell Biol (2005) 2.19
Caveolin forms a hetero-oligomeric protein complex that interacts with an apical GPI-linked protein: implications for the biogenesis of caveolae. J Cell Biol (1993) 2.17
Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrP(Sc)) into contiguous membranes. EMBO J (2002) 2.16
Yes-associated protein 65 localizes p62(c-Yes) to the apical compartment of airway epithelia by association with EBP50. J Cell Biol (1999) 2.11
Protein kinase C activators inhibit receptor-mediated potocytosis by preventing internalization of caveolae. J Cell Biol (1994) 2.04
Segregation of heterotrimeric G proteins in cell surface microdomains. G(q) binds caveolin to concentrate in caveolae, whereas G(i) and G(s) target lipid rafts by default. Mol Biol Cell (2001) 2.02
Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolae. Mol Cell Biol (1995) 2.02
Different routes of bone morphogenic protein (BMP) receptor endocytosis influence BMP signaling. Mol Cell Biol (2006) 1.99
Assembly and trafficking of heterotrimeric G proteins. Biochemistry (2007) 1.98
Receptor regulation of G-protein palmitoylation. Proc Natl Acad Sci U S A (1994) 1.93
Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae. Mol Cell Biol (2002) 1.93
Specific association of glycoprotein B with lipid rafts during herpes simplex virus entry. J Virol (2003) 1.92
Identification of filamin as a novel ligand for caveolin-1: evidence for the organization of caveolin-1-associated membrane domains by the actin cytoskeleton. Mol Biol Cell (2000) 1.90
COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform. Proc Natl Acad Sci U S A (1997) 1.89
CR3 (Mac-1, alpha M beta 2, CD11b/CD18) and Fc gamma RIII cooperate in generation of a neutrophil respiratory burst: requirement for Fc gamma RIII and tyrosine phosphorylation. J Cell Biol (1994) 1.89
Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes. J Exp Med (1995) 1.89
Signal transduction of a G protein-coupled receptor in caveolae: colocalization of endothelin and its receptor with caveolin. Proc Natl Acad Sci U S A (1994) 1.88
Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins. Infect Immun (2001) 1.85
Specific release of membrane-bound annexin II and cortical cytoskeletal elements by sequestration of membrane cholesterol. Mol Biol Cell (1997) 1.84
A glycolipid-anchored prion protein is endocytosed via clathrin-coated pits. J Cell Biol (1994) 1.74
The MAL proteolipid is necessary for normal apical transport and accurate sorting of the influenza virus hemagglutinin in Madin-Darby canine kidney cells. J Cell Biol (1999) 1.68
Caveolin cycles between plasma membrane caveolae and the Golgi complex by microtubule-dependent and microtubule-independent steps. J Cell Biol (1995) 1.67
VIP36, a novel component of glycolipid rafts and exocytic carrier vesicles in epithelial cells. EMBO J (1994) 1.67
Annexins in cell membrane dynamics. Ca(2+)-regulated association of lipid microdomains. J Cell Biol (2000) 1.67
Annexin II tetramer: structure and function. Mol Cell Biochem (1996) 1.67
Caveolae from luminal plasmalemma of rat lung endothelium: microdomains enriched in caveolin, Ca(2+)-ATPase, and inositol trisphosphate receptor. Proc Natl Acad Sci U S A (1995) 1.66
Annexin XIIIb associates with lipid microdomains to function in apical delivery. J Cell Biol (1998) 1.65
Induction of caveolae in the apical plasma membrane of Madin-Darby canine kidney cells. J Cell Biol (2000) 1.63
Endocytosis of GPI-anchored proteins in human lymphocytes: role of glycolipid-based domains, actin cytoskeleton, and protein kinases. J Cell Biol (1996) 1.63
Distinct ligand binding sites in integrin alpha3beta1 regulate matrix adhesion and cell-cell contact. J Cell Biol (2003) 1.62
Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia. Am J Pathol (2002) 1.62
Phosphoinositides and phosphoinositide-utilizing enzymes in detergent-insoluble lipid domains. Mol Biol Cell (1996) 1.60
Sphingomyelin-enriched microdomains at the Golgi complex. Mol Biol Cell (2001) 1.55
Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion. Genes Dev (1999) 1.52
Caveolin transfection results in caveolae formation but not apical sorting of glycosylphosphatidylinositol (GPI)-anchored proteins in epithelial cells. J Cell Biol (1998) 1.51
Trafficking of prion proteins through a caveolae-mediated endosomal pathway. J Cell Biol (2003) 1.51
The human E48 antigen, highly homologous to the murine Ly-6 antigen ThB, is a GPI-anchored molecule apparently involved in keratinocyte cell-cell adhesion. J Cell Biol (1995) 1.51
Signal transduction in macrophages by glycosylphosphatidylinositols of Plasmodium, Trypanosoma, and Leishmania: activation of protein tyrosine kinases and protein kinase C by inositolglycan and diacylglycerol moieties. Proc Natl Acad Sci U S A (1997) 1.48
Plasma membrane microdomains: organization, function and trafficking. Mol Membr Biol (2004) 1.48
The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae. J Cell Biol (1995) 1.47
Caveolin-1 contributes to assembly of store-operated Ca2+ influx channels by regulating plasma membrane localization of TRPC1. J Biol Chem (2003) 1.46
Molecular genetics of the caveolin gene family: implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy. Am J Hum Genet (1998) 1.46
Epidermal growth factor receptor activation is localized within low-buoyant density, non-caveolar membrane domains. Biochem J (1999) 1.42
Ligand-induced protease receptor translocation into caveolae: a mechanism for regulating cell surface proteolysis of the tissue factor-dependent coagulation pathway. J Cell Biol (1996) 1.41
The Src family kinase c-Yes is required for maturation of West Nile virus particles. J Virol (2005) 1.39
Traffic, polarity, and detergent solubility of a glycosylphosphatidylinositol-anchored protein after LDL-deprivation of MDCK cells. J Cell Biol (1996) 1.39
Different sphingolipids show differential partitioning into sphingolipid/cholesterol-rich domains in lipid bilayers. Biophys J (2000) 1.37
Organization of G proteins and adenylyl cyclase at the plasma membrane. Mol Biol Cell (1997) 1.37
Agonist-selective signaling is determined by the receptor location within the membrane domains. Proc Natl Acad Sci U S A (2008) 1.36
The sorbin homology domain: a motif for the targeting of proteins to lipid rafts. Proc Natl Acad Sci U S A (2001) 1.35
Insulin stimulates the tyrosine phosphorylation of caveolin. J Cell Biol (1995) 1.35
Dual pathways of internalization of the cholecystokinin receptor. J Cell Biol (1995) 1.33
Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells. Mol Biol Cell (2002) 1.32
Endocytosis of GPI-linked membrane folate receptor-alpha. J Cell Biol (1996) 1.31
Transgenic overexpression of caveolin-3 in skeletal muscle fibers induces a Duchenne-like muscular dystrophy phenotype. Proc Natl Acad Sci U S A (2000) 1.31
Localization of autocrine motility factor receptor to caveolae and clathrin-independent internalization of its ligand to smooth endoplasmic reticulum. Mol Biol Cell (1998) 1.29
Caveolae structure and function. J Cell Mol Med (2008) 1.26
Caveolae participate in tumor necrosis factor receptor 1 signaling and internalization in a human endothelial cell line. Am J Pathol (2005) 1.26
Role of cholesterol in formation and function of a signaling complex involving alphavbeta3, integrin-associated protein (CD47), and heterotrimeric G proteins. J Cell Biol (1999) 1.26
Fluorescence-based evaluation of the partitioning of lipids and lipidated peptides into liquid-ordered lipid microdomains: a model for molecular partitioning into "lipid rafts". Biophys J (2000) 1.25
Intracellular retention of glycosylphosphatidyl inositol-linked proteins in caveolin-deficient cells. Mol Cell Biol (2002) 1.25
Fluorographic detection of radioactivity in polyacrylamide gels with the water-soluble fluor, sodium salicylate. Anal Biochem (1979) 22.03
Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell (1992) 17.81
Identification of a transformation-specific antigen induced by an avian sarcoma virus. Nature (1977) 16.32
Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. Methods Enzymol (1991) 15.04
Caveolin, a protein component of caveolae membrane coats. Cell (1992) 12.50
Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem (1987) 10.61
Morphogenesis of the polarized epithelial cell phenotype. Science (1989) 7.54
GPI-anchored cell-surface molecules complexed to protein tyrosine kinases. Science (1991) 6.06
Selective solubilization of proteins and phospholipids from red blood cell membranes by nonionic detergents. J Supramol Struct (1973) 4.95
Potocytosis: sequestration and transport of small molecules by caveolae. Science (1992) 4.94
VIP21, a 21-kD membrane protein is an integral component of trans-Golgi-network-derived transport vesicles. J Cell Biol (1992) 4.81
Polarized sorting in epithelia. Cell (1990) 4.72
Cholesterol controls the clustering of the glycophospholipid-anchored membrane receptor for 5-methyltetrahydrofolate. J Cell Biol (1990) 4.37
Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins. Nature (1982) 4.22
Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton. J Cell Biol (1989) 4.20
Caveolae and sorting in the trans-Golgi network of epithelial cells. EMBO J (1993) 4.09
Polarity of epithelial and neuronal cells. Annu Rev Cell Biol (1992) 3.99
Glycolipid anchoring of plasma membrane proteins. Annu Rev Cell Biol (1990) 3.88
Mechanism of membrane anchoring affects polarized expression of two proteins in MDCK cells. Science (1989) 3.59
A glycophospholipid membrane anchor acts as an apical targeting signal in polarized epithelial cells. J Cell Biol (1989) 3.56
Permeability of muscle capillaries to small heme-peptides. Evidence for the existence of patent transendothelial channels. J Cell Biol (1975) 3.42
Polarized apical distribution of glycosyl-phosphatidylinositol-anchored proteins in a renal epithelial cell line. Proc Natl Acad Sci U S A (1988) 3.19
Vesicles and cisternae in the trans Golgi apparatus of human fibroblasts are acidic compartments. Cell (1985) 3.11
Distinct transport vesicles mediate the delivery of plasma membrane proteins to the apical and basolateral domains of MDCK cells. J Cell Biol (1990) 3.05
Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets. Proc Natl Acad Sci U S A (1991) 2.93
Tyrosine phosphorylation of a 22-kDa protein is correlated with transformation by Rous sarcoma virus. J Biol Chem (1989) 2.86
Calcium pump of the plasma membrane is localized in caveolae. J Cell Biol (1993) 2.85
Localization of inositol 1,4,5-trisphosphate receptor-like protein in plasmalemmal caveolae. J Cell Biol (1992) 2.72
Integral and peripheral protein composition of the apical and basolateral membrane domains in MDCK cells. J Membr Biol (1989) 2.65
Sequence and expression of caveolin, a protein component of caveolae plasma membrane domains phosphorylated on tyrosine in Rous sarcoma virus-transformed fibroblasts. Proc Natl Acad Sci U S A (1992) 2.62
A heterotrimeric G protein, G alpha i-3, on Golgi membranes regulates the secretion of a heparan sulfate proteoglycan in LLC-PK1 epithelial cells. J Cell Biol (1991) 2.58
Dynamin is a GTPase stimulated to high levels of activity by microtubules. Nature (1992) 2.45
A role for calpactin in calcium-dependent exocytosis in adrenal chromaffin cells. Nature (1989) 2.41
Glycosyl-phosphatidylinositol: a versatile anchor for cell surface proteins. FASEB J (1989) 2.31
Glycophospholipid membrane anchoring provides clues to the mechanism of protein sorting in polarized epithelial cells. Trends Biochem Sci (1990) 2.27
Aggregation of chromaffin granules by calpactin at micromolar levels of calcium. Nature (1988) 2.27
The glycophosphatidylinositol-anchored Thy-1 molecule interacts with the p60fyn protein tyrosine kinase in T cells. J Biol Chem (1992) 2.25
Caveolae: static inpocketings of the plasma membrane, dynamic vesicles or plain artifact? J Cell Sci (1988) 2.16
Biogenetic pathways of plasma membrane proteins in Caco-2, a human intestinal epithelial cell line. J Cell Biol (1990) 2.02
Annexin II is a major component of fusogenic endosomal vesicles. J Cell Biol (1993) 1.99
Endothelial plasmalemmal vesicles have a characteristic striped bipolar surface structure. J Cell Biol (1985) 1.94
The sequence of human caveolin reveals identity with VIP21, a component of transport vesicles. FEBS Lett (1992) 1.85
Ectoenzymes of the kidney microvillar membrane. Differential solubilization by detergents can predict a glycosyl-phosphatidylinositol membrane anchor. Biochem J (1988) 1.85
Role of heterotrimeric G proteins in membrane traffic. Mol Biol Cell (1992) 1.79
Glycosylphosphatidylinositol-anchored proteins are preferentially targeted to the basolateral surface in Fischer rat thyroid epithelial cells. J Cell Biol (1993) 1.78
Regulation of apical transport in epithelial cells by a Gs class of heterotrimeric G protein. Nature (1993) 1.77
Preferred apical distribution of glycosyl-phosphatidylinositol (GPI) anchored proteins: a highly conserved feature of the polarized epithelial cell phenotype. J Membr Biol (1990) 1.76
Microtubular organization and its involvement in the biogenetic pathways of plasma membrane proteins in Caco-2 intestinal epithelial cells. J Cell Biol (1991) 1.74
Selective radiolabeling of cell surface proteins to a high specific activity. Biochemistry (1987) 1.74
The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family. J Biol Chem (1991) 1.73
Transfer of proteins to membranes facilitates both cyanogen bromide cleavage and two-dimensional proteolytic mapping. Oncogene (1990) 1.71
Membrane localization of the pertussis toxin-sensitive G-protein subunits alpha i-2 and alpha i-3 and expression of a metallothionein-alpha i-2 fusion gene in LLC-PK1 cells. Proc Natl Acad Sci U S A (1990) 1.69
IgM antigen receptor complex contains phosphoprotein products of B29 and mb-1 genes. Proc Natl Acad Sci U S A (1991) 1.67
5'nucleotidase is sorted to the apical domain of hepatocytes via an indirect route. J Cell Biol (1992) 1.65
Membrane association of a 36,000-dalton substrate for tyrosine phosphorylation in chicken embryo fibroblasts transformed by avian sarcoma viruses. J Cell Biol (1983) 1.65
Pertussis toxin has eukaryotic-like carbohydrate recognition domains. Proc Natl Acad Sci U S A (1992) 1.56
Vectorial apical delivery and slow endocytosis of a glycolipid-anchored fusion protein in transfected MDCK cells. Proc Natl Acad Sci U S A (1990) 1.56
Association of specific cell-surface glycoproteins with a triton X-100-resistant complex of plasma membrane proteins isolated from T-lymphoma cells (P1798). Exp Cell Res (1985) 1.49
A glycophospholipid anchor is required for Qa-2-mediated T cell activation. Nature (1989) 1.48
Polarized assembly of enveloped viruses from cultured epithelial cells. Methods Enzymol (1983) 1.45
Early lipid intermediates in glycosyl-phosphatidylinositol anchor assembly are synthesized in the ER and located in the cytoplasmic leaflet of the ER membrane bilayer. J Cell Biol (1993) 1.43
Correctly sorted molecules of a GPI-anchored protein are clustered and immobile when they arrive at the apical surface of MDCK cells. J Cell Biol (1993) 1.41
Cellular proteins homologous to the viral yes gene product. Mol Cell Biol (1986) 1.40
Detergent extraction of cholera toxin and gangliosides from cultured cells and isolated membranes. Biochim Biophys Acta (1982) 1.39
GPI-anchored proteins associate to form microdomains during their intracellular transport in Caco-2 cells. J Cell Sci (1993) 1.36
The glycosyl phosphatidylinositol anchor is critical for Ly-6A/E-mediated T cell activation. J Cell Biol (1991) 1.32
Conformational change and localization of calpactin I complex involved in exocytosis as revealed by quick-freeze, deep-etch electron microscopy and immunocytochemistry. J Cell Biol (1990) 1.31
Mannosamine, a novel inhibitor of glycosylphosphatidylinositol incorporation into proteins. EMBO J (1991) 1.25
Isolation of a homogeneous glucosidase II from pig kidney microsomes. Eur J Biochem (1984) 1.22
The cholera toxin receptor ganglioside GM remains associated with triton X-100 cytoskeletons of BALB/c-3T3 cells. Exp Cell Res (1981) 1.20
Expression of cellular-yes protein in mammalian tissues. Oncogene (1990) 1.10
Changes in intracellular calcium during the development of epithelial polarity and junctions. Proc Natl Acad Sci U S A (1992) 1.08
Intestinal brush border membranes contain regulatory subunits of adenylyl cyclase. Proc Natl Acad Sci U S A (1987) 1.03
Fusion proteins containing a minimal GPI-attachment signal are apically expressed in transfected MDCK cells. J Cell Sci (1991) 1.02
Stimulation of tyrosine kinase activity in anti-phosphotyrosine immune complexes of Swiss 3T3 cell lysates occurs rapidly after addition of bombesin, vasopressin, and endothelin to intact cells. J Biol Chem (1991) 0.95
The T-cell receptor zeta chain contains a GTP/GDP binding site. EMBO J (1992) 0.92
Asymmetrical distribution of G-proteins among the apical and basolateral membranes of rat enterocytes. Biochem J (1991) 0.91
Affinity labeling of GTP-binding proteins in cellular extracts. FEBS Lett (1992) 0.90
Cholera toxin treatment stimulates tumorigenicity of Rous sarcoma virus-transformed cells. Mol Cell Biol (1984) 0.85
Vesicle traffic: G whizz. Curr Biol (1993) 0.84
c-yes protein kinase is associated with a 38 kD protein in cerebellum. Oncogene (1991) 0.83
Microinjection of antibodies to the calpactin I light chain in MDBK cells causes precipition of the cytoskeletal calpactin I complex without affecting the distribution of related proteins. Prog Clin Biol Res (1990) 0.82
Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. J Biol Chem (2001) 7.03
Interannual variability in net primary production and precipitation. Science (2001) 6.82
Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane. J Biol Chem (1998) 6.26
The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains. FASEB J (2000) 6.26
Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease. J Cell Biol (1994) 5.29
Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis. Trends Cell Biol (1994) 4.87
A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. Genes Dev (1998) 4.78
GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo. Genes Dev (1998) 4.72
Caveolins, liquid-ordered domains, and signal transduction. Mol Cell Biol (1999) 4.70
The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules. Proc Natl Acad Sci U S A (1995) 4.52
Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains. Detergent-free purification of caveolae microdomains. J Biol Chem (1996) 4.50
Identification of peptide and protein ligands for the caveolin-scaffolding domain. Implications for the interaction of caveolin with caveolae-associated proteins. J Biol Chem (1997) 4.12
A proline-rich motif within the matrix protein of vesicular stomatitis virus and rabies virus interacts with WW domains of cellular proteins: implications for viral budding. J Virol (1999) 3.92
Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the nos caveolin binding domain in vivo. J Biol Chem (1997) 3.80
Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation. Nat Genet (2000) 3.64
Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases. J Biol Chem (1996) 3.62
Evidence for a regulated interaction between heterotrimeric G proteins and caveolin. J Biol Chem (1995) 3.45
The WW domain: a signalling site in dystrophin? Trends Biochem Sci (1994) 3.18
Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins. J Biol Chem (1997) 3.14
Oligomeric structure of caveolin: implications for caveolae membrane organization. Proc Natl Acad Sci U S A (1995) 3.13
Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide. Nature (1996) 3.11
WW domains and retrovirus budding. Nature (1996) 3.10
Emerging themes in lipid rafts and caveolae. Cell (2001) 3.09
Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins. J Biol Chem (1996) 3.05
Reduction of caveolin and caveolae in oncogenically transformed cells. Proc Natl Acad Sci U S A (1995) 3.03
Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle. J Biol Chem (1996) 2.95
Physical interaction with Yes-associated protein enhances p73 transcriptional activity. J Biol Chem (2001) 2.93
Differential targeting of beta -adrenergic receptor subtypes and adenylyl cyclase to cardiomyocyte caveolae. A mechanism to functionally regulate the cAMP signaling pathway. J Biol Chem (2000) 2.86
Association of the polyomavirus middle-T antigen with c-yes protein. Nature (1987) 2.78
Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo. J Biol Chem (1997) 2.74
Mutations in the caveolin-3 gene cause autosomal dominant limb-girdle muscular dystrophy. Nat Genet (1998) 2.72
Induction of caveolin during adipogenesis and association of GLUT4 with caveolin-rich vesicles. J Cell Biol (1994) 2.69
Identification, sequence, and expression of caveolin-2 defines a caveolin gene family. Proc Natl Acad Sci U S A (1996) 2.68
Gpa2p, a G-protein alpha-subunit, regulates growth and pseudohyphal development in Saccharomyces cerevisiae via a cAMP-dependent mechanism. J Biol Chem (1997) 2.63
Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities. J Biol Chem (2001) 2.62
Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor. J Biol Chem (2000) 2.56
Functional haploinsufficiency of the human homeobox gene MSX2 causes defects in skull ossification. Nat Genet (2000) 2.55
Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities. J Biol Chem (1997) 2.52
Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain. FEBS Lett (1998) 2.40
Negative regulation of the wee1 protein kinase by direct action of the nim1/cdr1 mitotic inducer. Cell (1993) 2.38
Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth. J Biol Chem (1997) 2.34
Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe. J Biol Chem (1995) 2.25
Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade. EMBO J (1998) 2.23
Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity. J Biol Chem (2001) 2.16
Integration of FGF and TWIST in calvarial bone and suture development. Development (2000) 2.15
Yes-associated protein 65 localizes p62(c-Yes) to the apical compartment of airway epithelia by association with EBP50. J Cell Biol (1999) 2.11
Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands. J Biol Chem (1997) 2.08
Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette. Mol Endocrinol (2000) 2.04
Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism. Mol Biol Cell (2001) 2.00
Caveolin-2 localizes to the golgi complex but redistributes to plasma membrane, caveolae, and rafts when co-expressed with caveolin-1. J Biol Chem (1999) 2.00
Phosphorylation of caveolin by src tyrosine kinases. The alpha-isoform of caveolin is selectively phosphorylated by v-Src in vivo. J Biol Chem (1996) 1.93
The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled. J Biol Chem (1997) 1.92
An azoospermic man with a de novo point mutation in the Y-chromosomal gene USP9Y. Nat Genet (1999) 1.91
Structure of a WW domain containing fragment of dystrophin in complex with beta-dystroglycan. Nat Struct Biol (2000) 1.89
Signal transduction of a G protein-coupled receptor in caveolae: colocalization of endothelin and its receptor with caveolin. Proc Natl Acad Sci U S A (1994) 1.88
The lipopolysaccharide-activated toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes. J Biol Chem (2000) 1.87
GATA-5: a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development. Dev Biol (1997) 1.83
Caveolae-deficient endothelial cells show defects in the uptake and transport of albumin in vivo. J Biol Chem (2001) 1.82
Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane. Retention of caveolin-2 at the level of the golgi complex. J Biol Chem (1999) 1.79
Glycosylphosphatidylinositol-anchored proteins are preferentially targeted to the basolateral surface in Fischer rat thyroid epithelial cells. J Cell Biol (1993) 1.78
Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis. J Biol Chem (1998) 1.77
The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways. J Biol Chem (2000) 1.77
Hormonal regulation of plasminogen activator mRNA production in porcine kidney cells. Cell (1983) 1.76
Point-of-care glucose testing: effects of critical care variables, influence of reference instruments, and a modular glucose meter design. Arch Pathol Lab Med (2000) 1.76
WW: An isolated three-stranded antiparallel beta-sheet domain that unfolds and refolds reversibly; evidence for a structured hydrophobic cluster in urea and GdnHCl and a disordered thermal unfolded state. Protein Sci (1999) 1.75
Caveolin-deficient mice: insights into caveolar function human disease. J Clin Invest (2001) 1.71
The GATA-4 transcription factor transactivates the cardiac muscle-specific troponin C promoter-enhancer in nonmuscle cells. Mol Cell Biol (1994) 1.70
Caveolin is an activator of insulin receptor signaling. J Biol Chem (1998) 1.66
GATA-4 activates transcription via two novel domains that are conserved within the GATA-4/5/6 subfamily. J Biol Chem (1997) 1.66
Caveolin interaction with protein kinase C. Isoenzyme-dependent regulation of kinase activity by the caveolin scaffolding domain peptide. J Biol Chem (1997) 1.66
Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer. J Biol Chem (1998) 1.61
Yes-associated protein and p53-binding protein-2 interact through their WW and SH3 domains. J Biol Chem (2001) 1.58
Towards prediction of cognate complexes between the WW domain and proline-rich ligands. FEBS Lett (1996) 1.58
Caveolin-3 in muscular dystrophy. Hum Mol Genet (1998) 1.55
Caveolae purification and glycosylphosphatidylinositol-linked protein sorting in polarized epithelia. Methods Enzymol (1995) 1.54
Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains. J Biol Chem (2000) 1.51
Mutational analysis of the properties of caveolin-1. A novel role for the C-terminal domain in mediating homo-typic caveolin-caveolin interactions. J Biol Chem (1997) 1.51
A molecular dissection of caveolin-1 membrane attachment and oligomerization. Two separate regions of the caveolin-1 C-terminal domain mediate membrane binding and oligomer/oligomer interactions in vivo. J Biol Chem (2000) 1.50
Crowded little caves: structure and function of caveolae. Cell Signal (1998) 1.49
Expression and characterization of recombinant caveolin. Purification by polyhistidine tagging and cholesterol-dependent incorporation into defined lipid membranes. J Biol Chem (1996) 1.47
Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers. FEBS Lett (1998) 1.47
Rsp5 WW domains interact directly with the carboxyl-terminal domain of RNA polymerase II. J Biol Chem (2000) 1.46
Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways. Mol Med (2001) 1.46
Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1. Mol Cell Biol (2001) 1.46
Molecular genetics of the caveolin gene family: implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy. Am J Hum Genet (1998) 1.46
Isolation and preliminary characterization of clathrin-associated proteins. Eur J Biochem (1982) 1.44
Adhesion-dependent tyrosine phosphorylation of (beta)-dystroglycan regulates its interaction with utrophin. J Cell Sci (2000) 1.44
Phenotypic behavior of caveolin-3 mutations that cause autosomal dominant limb girdle muscular dystrophy (LGMD-1C). Retention of LGMD-1C caveolin-3 mutants within the golgi complex. J Biol Chem (1999) 1.43
Regulation of G protein-coupled receptor kinases by caveolin. J Biol Chem (1999) 1.42
Correctly sorted molecules of a GPI-anchored protein are clustered and immobile when they arrive at the apical surface of MDCK cells. J Cell Biol (1993) 1.41
Elevated expression of caveolin-1 in adenocarcinoma of the colon. Am J Clin Pathol (2001) 1.41