Published in Sci Rep on May 13, 2016
Comparative Proteomics of Purified Pathogen Vacuoles Correlates Intracellular Replication of Legionella pneumophila with the Small GTPase Ras-related protein 1 (Rap1). Mol Cell Proteomics (2017) 0.75
Dual TORCs driven and B56 orchestrated Signaling Network guides eukaryotic cell migration. BMB Rep (2017) 0.75
Auxin Signaling in Regulation of Plant Translation Reinitiation. Front Plant Sci (2017) 0.75
mTOR signaling in growth control and disease. Cell (2012) 29.21
Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer (2004) 14.55
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat Cell Biol (2004) 12.12
A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res (2004) 7.56
Rheb binds and regulates the mTOR kinase. Curr Biol (2005) 6.09
Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop. Cancer Res (2005) 4.33
Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement. J Cell Biol (2004) 3.44
Activation of mTORC2 by association with the ribosome. Cell (2011) 3.38
PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis. Curr Biol (2008) 3.06
TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium. Mol Biol Cell (2005) 2.76
mTOR complex 2 signaling and functions. Cell Cycle (2011) 2.66
Wound repair at a glance. J Cell Sci (2009) 2.53
mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide. EMBO J (2010) 2.35
Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size. Mol Cell (2011) 2.32
Mechanisms of collective cell migration at a glance. J Cell Sci (2009) 2.15
Molecular organization of target of rapamycin complex 2. J Biol Chem (2005) 2.15
A novel cytosolic regulator, Pianissimo, is required for chemoattractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase in Dictyostelium. Genes Dev (1997) 1.82
Recognizing and defining true Ras binding domains I: biochemical analysis. J Mol Biol (2005) 1.76
A Ras signaling complex controls the RasC-TORC2 pathway and directed cell migration. Dev Cell (2010) 1.74
A novel Ras-interacting protein required for chemotaxis and cyclic adenosine monophosphate signal relay in Dictyostelium. Mol Biol Cell (1999) 1.72
Ras-mediated activation of the TORC2-PKB pathway is critical for chemotaxis. J Cell Biol (2010) 1.64
Chemoattractant-induced Ras activation during Dictyostelium aggregation. EMBO Rep (2004) 1.63
Spatiotemporal regulation of Ras activity provides directional sensing. Curr Biol (2008) 1.60
A new set of small, extrachromosomal expression vectors for Dictyostelium discoideum. Plasmid (2008) 1.60
A novel Akt/PKB-related kinase is essential for morphogenesis in Dictyostelium. Curr Biol (2000) 1.58
Rap1 controls cell adhesion and cell motility through the regulation of myosin II. J Cell Biol (2007) 1.45
Delineation of the roles played by RasG and RasC in cAMP-dependent signal transduction during the early development of Dictyostelium discoideum. Mol Biol Cell (2006) 1.36
Dictyostelium Ric8 is a nonreceptor guanine exchange factor for heterotrimeric G proteins and is important for development and chemotaxis. Proc Natl Acad Sci U S A (2013) 1.34
Human Sin1 contains Ras-binding and pleckstrin homology domains and suppresses Ras signalling. Cell Signal (2007) 1.29
Review series: TOR kinase complexes and cell migration. J Cell Biol (2011) 1.19
Rab-family GTPase regulates TOR complex 2 signaling in fission yeast. Curr Biol (2010) 1.15
Characterization of the GbpD-activated Rap1 pathway regulating adhesion and cell polarity in Dictyostelium discoideum. J Biol Chem (2006) 1.14
Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells. J Cell Biol (2007) 1.04
Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs. EMBO Rep (2007) 1.01
Oscillatory signaling and network responses during the development of Dictyostelium discoideum. Ageing Res Rev (2008) 1.01
Chemotactic activation of Dictyostelium AGC-family kinases AKT and PKBR1 requires separate but coordinated functions of PDK1 and TORC2. J Cell Sci (2010) 0.99
Signal relay during chemotaxis. J Microsc (2008) 0.98
A Rap/phosphatidylinositol 3-kinase pathway controls pseudopod formation [corrected]. Mol Biol Cell (2010) 0.96
Rap1 activation in response to cAMP occurs downstream of ras activation during Dictyostelium aggregation. J Biol Chem (2008) 0.95
Regulation of actin cytoskeleton by Rap1 binding to RacGEF1. Mol Cells (2012) 0.85
Daydreamer, a Ras effector and GSK-3 substrate, is important for directional sensing and cell motility. Mol Biol Cell (2012) 0.85
GxcC connects Rap and Rac signaling during Dictyostelium development. BMC Cell Biol (2013) 0.83
Regulation of a LATS-homolog by Ras GTPases is important for the control of cell division. BMC Cell Biol (2014) 0.79
Rap1-dependent pathways coordinate cytokinesis in Dictyostelium. Mol Biol Cell (2014) 0.79
PP2A/B56 and GSK3/Ras suppress PKB activity during Dictyostelium chemotaxis. Mol Biol Cell (2015) 0.76
Determinants of RasC specificity during Dictyostelium aggregation. J Biol Chem (2010) 0.78