QuadBase2: web server for multiplexed guanine quadruplex mining and visualization.

PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA. Nat Commun (2017) 0.75

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription. Proc Natl Acad Sci U S A (2002) 9.60

Ensembl 2015. Nucleic Acids Res (2014) 8.30

Prevalence of quadruplexes in the human genome. Nucleic Acids Res (2005) 7.79

Helix formation by guanylic acid. Proc Natl Acad Sci U S A (1962) 6.77

Highly prevalent putative quadruplex sequence motifs in human DNA. Nucleic Acids Res (2005) 5.34

Quantitative visualization of DNA G-quadruplex structures in human cells. Nat Chem (2013) 4.61

DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase. Cell (2011) 3.70

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy? Nat Rev Drug Discov (2011) 3.54

Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics. Nucleic Acids Res (2007) 3.49

Loop-length-dependent folding of G-quadruplexes. J Am Chem Soc (2004) 3.16

DNA secondary structures: stability and function of G-quadruplex structures. Nat Rev Genet (2012) 3.15

Gene function correlates with potential for G4 DNA formation in the human genome. Nucleic Acids Res (2006) 3.13

Unraveling cell type-specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs. Nat Struct Mol Biol (2012) 2.65

QGRS Mapper: a web-based server for predicting G-quadruplexes in nucleotide sequences. Nucleic Acids Res (2006) 2.62

An alternative DNA structure is necessary for pilin antigenic variation in Neisseria gonorrhoeae. Science (2009) 2.37

Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix. Nucleic Acids Res (2002) 2.35

PrimPol Is Required for Replicative Tolerance of G Quadruplexes in Vertebrate Cells. Mol Cell (2015) 2.22

CGG repeats associated with DNA instability and chromosome fragility form structures that block DNA synthesis in vitro. Nucleic Acids Res (1995) 2.13

Genome-wide prediction of G4 DNA as regulatory motifs: role in Escherichia coli global regulation. Genome Res (2006) 2.12

Detection of G-quadruplex DNA in mammalian cells. Nucleic Acids Res (2013) 1.53

Physiological relevance of telomeric G-quadruplex formation: a potential drug target. Bioessays (2007) 1.47

The Ensembl REST API: Ensembl Data for Any Language. Bioinformatics (2014) 1.43

QuadBase: genome-wide database of G4 DNA--occurrence and conservation in human, chimpanzee, mouse and rat promoters and 146 microbes. Nucleic Acids Res (2007) 1.35

Metastases suppressor NM23-H2 interaction with G-quadruplex DNA within c-MYC promoter nuclease hypersensitive element induces c-MYC expression. Nucleic Acids Res (2008) 1.34

Bulges in G-quadruplexes: broadening the definition of G-quadruplex-forming sequences. J Am Chem Soc (2013) 1.26

GRSDB2 and GRS_UTRdb: databases of quadruplex forming G-rich sequences in pre-mRNAs and mRNAs. Nucleic Acids Res (2007) 1.24

G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD. Nat Chem Biol (2014) 1.22

Protein hnRNP A1 and its derivative Up1 unfold quadruplex DNA in the human KRAS promoter: implications for transcription. Nucleic Acids Res (2009) 1.16

Discovery of alternative DNA structures: a heroic decade (1979-1989). Front Biosci (2008) 1.16

Genome-wide analyses of recombination prone regions predict role of DNA structural motif in recombination. PLoS One (2009) 1.14

Inosine substitutions demonstrate that intramolecular DNA quadruplexes adopt different conformations in the presence of sodium and potassium. Bioorg Med Chem Lett (2005) 1.08

Stable G-quadruplexes are found outside nucleosome-bound regions. Mol Biosyst (2009) 1.07

Guanine quadruplex DNA structure restricts methylation of CpG dinucleotides genome-wide. Mol Biosyst (2010) 1.06

Genome-wide study predicts promoter-G4 DNA motifs regulate selective functions in bacteria: radioresistance of D. radiodurans involves G4 DNA-mediated regulation. Nucleic Acids Res (2012) 1.06

The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-element. J Biol Chem (2010) 1.03

Genome-wide analysis predicts DNA structural motifs as nucleosome exclusion signals. Mol Biosyst (2009) 1.02

Identifying hydrogen bond alignments in multistranded DNA architectures by NMR. Acc Chem Res (2002) 0.98

QGRS-H Predictor: a web server for predicting homologous quadruplex forming G-rich sequence motifs in nucleotide sequences. Nucleic Acids Res (2012) 0.97

Short loop length and high thermal stability determine genomic instability induced by G-quadruplex-forming minisatellites. EMBO J (2015) 0.94

Re-evaluation of G-quadruplex propensity with G4Hunter. Nucleic Acids Res (2016) 0.89

Existence of G-quadruplex structures in promoter region of oncogenes confirmed by G-quadruplex DNA cross-linking strategy. Sci Rep (2013) 0.88

Probing telomeric G-quadruplex DNA structures in cells with in vitro generated single-chain antibody fragments. Methods Mol Biol (2010) 0.88