PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.

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Published in Nat Commun on April 27, 2017

Authors

Tovah A Day1, Jacob V Layer1, J Patrick Cleary1, Srijoy Guha1, Kristen E Stevenson2, Trevor Tivey1, Sunhee Kim1, Anna C Schinzel3, Francesca Izzo1,3, John Doench3, David E Root3, William C Hahn1,3, Brendan D Price4, David M Weinstock1,3

Author Affiliations

1: Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
2: Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
3: Genetic Perturbation Platform, Broad Institute of MIT and Harvard University, 415 Main Street, Cambridge, Massachusetts 02142, USA.
4: Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.

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