Published in FEBS J on June 22, 2016
Patterns of CRISPR/Cas9 activity in plants, animals and microbes. Plant Biotechnol J (2016) 0.85
FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2017 update. Nucleic Acids Res (2016) 0.76
Efficient Screening of CRISPR/Cas9-Induced Events in Drosophila Using a co-CRISPR Strategy. G3 (Bethesda) (2016) 0.75
microTaboo: a general and practical solution to the k-disjoint problem. BMC Bioinformatics (2017) 0.75
Progress and Prospects of CRISPR/Cas Systems in Insects and Other Arthropods. Front Physiol (2017) 0.75
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science (2012) 48.17
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell (2013) 13.43
Genome-scale CRISPR-Cas9 knockout screening in human cells. Science (2013) 12.36
Genetic screens in human cells using the CRISPR-Cas9 system. Science (2013) 10.75
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes. Cell (2013) 9.55
CRISPR-Cas systems for editing, regulating and targeting genomes. Nat Biotechnol (2014) 9.18
RefSeq: an update on mammalian reference sequences. Nucleic Acids Res (2013) 7.29
TALENs: a widely applicable technology for targeted genome editing. Nat Rev Mol Cell Biol (2012) 7.01
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System. Cell (2015) 5.97
Zinc-finger nucleases: the next generation emerges. Mol Ther (2008) 5.69
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases. Nat Biotechnol (2014) 5.69
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Cell (2014) 5.43
In vivo genome editing using Staphylococcus aureus Cas9. Nature (2015) 5.26
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. Nature (2014) 5.19
E-CRISP: fast CRISPR target site identification. Nat Methods (2014) 2.73
CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences. Nucleic Acids Res (2014) 2.59
CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing. Nucleic Acids Res (2014) 2.36
The UCSC Genome Browser database: 2016 update. Nucleic Acids Res (2015) 2.18
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9. Nat Biotechnol (2016) 2.05
Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors. Nat Biotechnol (2015) 2.03
Biology and Applications of CRISPR Systems: Harnessing Nature's Toolbox for Genome Engineering. Cell (2016) 2.02
Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains. Nat Biotechnol (2015) 1.83
Microhomology-based choice of Cas9 nuclease target sites. Nat Methods (2014) 1.82
Highly efficient Cas9-mediated transcriptional programming. Nat Methods (2015) 1.81
High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities. Cell (2015) 1.76
CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites. Bioinformatics (2014) 1.57
Dramatic enhancement of genome editing by CRISPR/Cas9 through improved guide RNA design. Genetics (2015) 1.52
Target specificity of the CRISPR-Cas9 system. Quant Biol (2014) 1.23
Nucleosomes impede Cas9 access to DNA in vivo and in vitro. Elife (2016) 1.20
Quantifying on- and off-target genome editing. Trends Biotechnol (2015) 1.15
Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference. Nucleic Acids Res (2015) 1.10
CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. Cell Stem Cell (2016) 1.08
Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq. Genome Res (2016) 1.01
Potential pitfalls of CRISPR/Cas9-mediated genome editing. FEBS J (2015) 0.98
Genetic screens and functional genomics using CRISPR/Cas9 technology. FEBS J (2015) 0.94
CRISPR-ERA: a comprehensive design tool for CRISPR-mediated gene editing, repression and activation. Bioinformatics (2015) 0.93
Ensembl comparative genomics resources. Database (Oxford) (2016) 0.87
Keeping CRISPR/Cas on-Target. Curr Issues Mol Biol (2015) 0.82
Effective knockdown of Drosophila long non-coding RNAs by CRISPR interference. Nucleic Acids Res (2016) 0.80
CRISPR Technology for Genome Activation and Repression in Mammalian Cells. Cold Spring Harb Protoc (2016) 0.79