Published in Nucleic Acids Res on November 19, 2013
ClinVar: public archive of relationships among sequence variation and human phenotype. Nucleic Acids Res (2013) 9.31
A draft map of the human proteome. Nature (2014) 6.58
The UCSC Genome Browser database: 2015 update. Nucleic Acids Res (2014) 4.87
Ensembl 2016. Nucleic Acids Res (2015) 3.61
The landscape of long noncoding RNAs in the human transcriptome. Nat Genet (2015) 3.58
FlyBase: introduction of the Drosophila melanogaster Release 6 reference genome assembly and large-scale migration of genome annotations. Nucleic Acids Res (2014) 3.12
PHASTER: a better, faster version of the PHAST phage search tool. Nucleic Acids Res (2016) 2.75
PhosphoSitePlus, 2014: mutations, PTMs and recalibrations. Nucleic Acids Res (2014) 2.66
The UCSC Genome Browser database: 2016 update. Nucleic Acids Res (2015) 2.18
Gene: a gene-centered information resource at NCBI. Nucleic Acids Res (2014) 2.00
Expert curation in UniProtKB: a case study on dealing with conflicting and erroneous data. Database (Oxford) (2014) 1.94
The Ensembl Variant Effect Predictor. Genome Biol (2016) 1.80
The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases. Nucleic Acids Res (2015) 1.62
Genome-wide nucleosome specificity and function of chromatin remodellers in ES cells. Nature (2016) 1.58
Long non-coding RNAs as a source of new peptides. Elife (2014) 1.56
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. Nat Genet (2015) 1.55
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Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer. Nat Genet (2016) 1.48
The Diguanylate Cyclase HsbD Intersects with the HptB Regulatory Cascade to Control Pseudomonas aeruginosa Biofilm and Motility. PLoS Genet (2016) 1.40
Translation of 5' leaders is pervasive in genes resistant to eIF2 repression. Elife (2015) 1.40
Decreased Expression of CoREST1 and CoREST2 Together with LSD1 and HDAC1/2 during Neuronal Differentiation. PLoS One (2015) 1.39
A whole-genome shotgun approach for assembling and anchoring the hexaploid bread wheat genome. Genome Biol (2015) 1.38
An update on LNCipedia: a database for annotated human lncRNA sequences. Nucleic Acids Res (2014) 1.34
RNAcentral: an international database of ncRNA sequences. Nucleic Acids Res (2014) 1.32
Comparison of Exome and Genome Sequencing Technologies for the Complete Capture of Protein-Coding Regions. Hum Mutat (2015) 1.32
The Ensembl gene annotation system. Database (Oxford) (2016) 1.31
Transcriptome sequencing reveals altered long intergenic non-coding RNAs in lung cancer. Genome Biol (2014) 1.25
Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets. Diabetes (2015) 1.21
NONCODE 2016: an informative and valuable data source of long non-coding RNAs. Nucleic Acids Res (2015) 1.21
BiGG Models: A platform for integrating, standardizing and sharing genome-scale models. Nucleic Acids Res (2015) 1.18
COXPRESdb in 2015: coexpression database for animal species by DNA-microarray and RNAseq-based expression data with multiple quality assessment systems. Nucleic Acids Res (2014) 1.14
The SUPERFAMILY 1.75 database in 2014: a doubling of data. Nucleic Acids Res (2014) 1.13
Comparison of RNA-seq and microarray-based models for clinical endpoint prediction. Genome Biol (2015) 1.10
Bipartite structure of the inactive mouse X chromosome. Genome Biol (2015) 1.10
The Eukaryotic Promoter Database: expansion of EPDnew and new promoter analysis tools. Nucleic Acids Res (2014) 1.09
MOPED 2.5--an integrated multi-omics resource: multi-omics profiling expression database now includes transcriptomics data. OMICS (2014) 1.09
In silico prediction of splice-altering single nucleotide variants in the human genome. Nucleic Acids Res (2014) 1.08
Prediction of Causal Candidate Genes in Coronary Artery Disease Loci. Arterioscler Thromb Vasc Biol (2015) 1.08
Transcriptional consequences of 16p11.2 deletion and duplication in mouse cortex and multiplex autism families. Am J Hum Genet (2014) 1.08
Folding simulations for proteins with diverse topologies are accessible in days with a physics-based force field and implicit solvent. J Am Chem Soc (2014) 1.07
miRBase Tracker: keeping track of microRNA annotation changes. Database (Oxford) (2014) 1.06
Tissue-specific transcriptome sequencing analysis expands the non-human primate reference transcriptome resource (NHPRTR). Nucleic Acids Res (2014) 1.03
dbSUPER: a database of super-enhancers in mouse and human genome. Nucleic Acids Res (2015) 1.02
Redox regulation of FoxO transcription factors. Redox Biol (2015) 1.01
Functional classification of memory CD8(+) T cells by CX3CR1 expression. Nat Commun (2015) 1.00
Integrative genomic deconvolution of rheumatoid arthritis GWAS loci into gene and cell type associations. Genome Biol (2016) 1.00
Characterization of Greater Middle Eastern genetic variation for enhanced disease gene discovery. Nat Genet (2016) 0.97
Comparison of GENCODE and RefSeq gene annotation and the impact of reference geneset on variant effect prediction. BMC Genomics (2015) 0.96
Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells. Proc Natl Acad Sci U S A (2016) 0.96
Biological databases for human research. Genomics Proteomics Bioinformatics (2015) 0.96
TOLLIP, MUC5B, and the Response to N-Acetylcysteine among Individuals with Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med (2015) 0.95
Intron retention is a widespread mechanism of tumor-suppressor inactivation. Nat Genet (2015) 0.95
BGMUT Database of Allelic Variants of Genes Encoding Human Blood Group Antigens. Transfus Med Hemother (2014) 0.95
Utility of whole-genome sequencing for detection of newborn screening disorders in a population cohort of 1,696 neonates. Genet Med (2015) 0.95
Enhanced virome sequencing using targeted sequence capture. Genome Res (2015) 0.94
A widespread role of the motif environment in transcription factor binding across diverse protein families. Genome Res (2015) 0.94
DIANA-LncBase v2: indexing microRNA targets on non-coding transcripts. Nucleic Acids Res (2015) 0.93
Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation. EMBO Rep (2015) 0.93
Topological analysis of Hedgehog acyltransferase, a multipalmitoylated transmembrane protein. J Biol Chem (2014) 0.92
The promise and peril of genomic screening in the general population. Genet Med (2015) 0.92
The UniProtKB guide to the human proteome. Database (Oxford) (2016) 0.92
Uncovering the novel characteristics of Asian honey bee, Apis cerana, by whole genome sequencing. BMC Genomics (2015) 0.92
NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol (2016) 0.91
Benchmark analysis of algorithms for determining and quantifying full-length mRNA splice forms from RNA-seq data. Bioinformatics (2015) 0.91
Creating reference gene annotation for the mouse C57BL6/J genome assembly. Mamm Genome (2015) 0.91
The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog). Nucleic Acids Res (2016) 0.91
Distinct isoform of FABP7 revealed by screening for retroelement-activated genes in diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A (2014) 0.91
Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer. Cancer Discov (2015) 0.90
PlanMine - a mineable resource of planarian biology and biodiversity. Nucleic Acids Res (2015) 0.90
Metagenome-assembled genomes uncover a global brackish microbiome. Genome Biol (2015) 0.90
Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs. Genome Biol (2016) 0.90
Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus. Hum Mol Genet (2015) 0.90
Pan-cancer transcriptome analysis reveals long noncoding RNAs with conserved function. RNA Biol (2015) 0.90
Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies. Genome Biol (2017) 0.90
Control of steroid receptor dynamics and function by genomic actions of the cochaperones p23 and Bag-1L. Nucl Recept Signal (2014) 0.89
Using ClinVar as a Resource to Support Variant Interpretation. Curr Protoc Hum Genet (2016) 0.89
Translational control by lysine-encoding A-rich sequences. Sci Adv (2015) 0.88
Key challenges for the creation and maintenance of specialist protein resources. Proteins (2015) 0.88
microRNAs regulate cell-to-cell variability of endogenous target gene expression in developing mouse thymocytes. PLoS Genet (2015) 0.88
Design and application of a target capture sequencing of exons and conserved non-coding sequences for the rat. BMC Genomics (2016) 0.88
Long non-coding RNA Databases in Cardiovascular Research. Genomics Proteomics Bioinformatics (2016) 0.87
Medical genomics: The intricate path from genetic variant identification to clinical interpretation. Appl Transl Genom (2014) 0.87
Leveraging transcript quantification for fast computation of alternative splicing profiles. RNA (2015) 0.87
High-performance web services for querying gene and variant annotation. Genome Biol (2016) 0.87
NCG 5.0: updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings. Nucleic Acids Res (2015) 0.86
An interactive environment for agile analysis and visualization of ChIP-sequencing data. Nat Struct Mol Biol (2016) 0.86
NPInter v3.0: an upgraded database of noncoding RNA-associated interactions. Database (Oxford) (2016) 0.86
Mutational Landscape of Aggressive Prostate Tumors in African American Men. Cancer Res (2016) 0.85
Beyond protein expression, MOPED goes multi-omics. Nucleic Acids Res (2014) 0.85
Under-detection of endospore-forming Firmicutes in metagenomic data. Comput Struct Biotechnol J (2015) 0.85
The Role of MicroRNAs as Predictors of Response to Tamoxifen Treatment in Breast Cancer Patients. Int J Mol Sci (2015) 0.85
Integrating 400 million variants from 80,000 human samples with extensive annotations: towards a knowledge base to analyze disease cohorts. BMC Bioinformatics (2016) 0.84
Current strategies for mutation detection in phenotype-driven screens utilising next generation sequencing. Mamm Genome (2015) 0.84
What's that gene (or protein)? Online resources for exploring functions of genes, transcripts, and proteins. Mol Biol Cell (2014) 0.84
HistoneDB 2.0: a histone database with variants-an integrated resource to explore histones and their variants. Database (Oxford) (2016) 0.84
Bovine Genome Database: new tools for gleaning function from the Bos taurus genome. Nucleic Acids Res (2015) 0.84
The novel homozygous KCNJ10 c.986T>C (p.(Leu329Pro)) variant is pathogenic for the SeSAME/EAST homologue in Malinois dogs. Eur J Hum Genet (2016) 0.84
Gene Expression Variation Resolves Species and Individual Strains among Coral-Associated Dinoflagellates within the Genus Symbiodinium. Genome Biol Evol (2016) 0.84
Panel-based NGS Reveals Novel Pathogenic Mutations in Autosomal Recessive Retinitis Pigmentosa. Sci Rep (2016) 0.83
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors. Nat Chem Biol (2016) 0.83
dbSNP: the NCBI database of genetic variation. Nucleic Acids Res (2001) 76.97
Prediction of complete gene structures in human genomic DNA. J Mol Biol (1997) 58.76
miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res (2010) 25.85
Introducing RefSeq and LocusLink: curated human genome resources at the NCBI. Trends Genet (2000) 19.33
The consensus coding sequence (CCDS) project: Identifying a common protein-coding gene set for the human and mouse genomes. Genome Res (2009) 14.90
A mitochondrial protein compendium elucidates complex I disease biology. Cell (2008) 13.51
McKusick's Online Mendelian Inheritance in Man (OMIM). Nucleic Acids Res (2008) 12.83
Update on activities at the Universal Protein Resource (UniProt) in 2013. Nucleic Acids Res (2012) 9.65
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2012) 8.41
Modernizing reference genome assemblies. PLoS Biol (2011) 5.23
Splign: algorithms for computing spliced alignments with identification of paralogs. Biol Direct (2008) 5.03
The International Nucleotide Sequence Database Collaboration. Nucleic Acids Res (2012) 4.91
Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans. Proc Natl Acad Sci U S A (2009) 4.58
Locus Reference Genomic sequences: an improved basis for describing human DNA variants. Genome Med (2010) 4.19
The Rat Genome Database 2009: variation, ontologies and pathways. Nucleic Acids Res (2008) 3.92
Genenames.org: the HGNC resources in 2013. Nucleic Acids Res (2012) 3.69
NMD: a multifaceted response to premature translational termination. Nat Rev Mol Cell Biol (2012) 3.64
Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation. Nucleic Acids Res (2006) 3.62
The IMGT/HLA database. Nucleic Acids Res (2012) 3.61
The NIH genetic testing registry: a new, centralized database of genetic tests to enable access to comprehensive information and improve transparency. Nucleic Acids Res (2012) 2.35
Locus Reference Genomic: reference sequences for the reporting of clinically relevant sequence variants. Nucleic Acids Res (2013) 2.18
The mouse genome database: genotypes, phenotypes, and models of human disease. Nucleic Acids Res (2012) 1.98
A perspective on mammalian upstream open reading frame function. Int J Biochem Cell Biol (2013) 1.59
Genome-wide annotation and quantitation of translation by ribosome profiling. Curr Protoc Mol Biol (2013) 1.30
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins. Nucleic Acids Res (2006) 48.10
NCBI Reference Sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins. Nucleic Acids Res (2005) 37.39
NCBI Reference Sequences: current status, policy and new initiatives. Nucleic Acids Res (2008) 26.04
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2005) 22.98
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2007) 22.53
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2008) 21.36
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2006) 18.85
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2006) 18.84
HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer (2007) 16.96
The consensus coding sequence (CCDS) project: Identifying a common protein-coding gene set for the human and mouse genomes. Genome Res (2009) 14.90
NCBI Reference Sequences (RefSeq): current status, new features and genome annotation policy. Nucleic Acids Res (2011) 14.04
Consensus statement: chromosomal microarray is a first-tier clinical diagnostic test for individuals with developmental disabilities or congenital anomalies. Am J Hum Genet (2010) 13.70
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2009) 12.51
Prepublication data sharing. Nature (2009) 12.24
NCBI Reference Sequence project: update and current status. Nucleic Acids Res (2003) 11.30
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2010) 10.97
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet (2007) 9.47
ClinVar: public archive of relationships among sequence variation and human phenotype. Nucleic Acids Res (2013) 9.31
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2011) 8.62
The TIGR Rice Genome Annotation Resource: improvements and new features. Nucleic Acids Res (2006) 8.26
The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science (2009) 8.23
The genome of the model beetle and pest Tribolium castaneum. Nature (2008) 6.50
The genome of the sea urchin Strongylocentrotus purpuratus. Science (2006) 6.41
Functional and evolutionary insights from the genomes of three parasitoid Nasonia species. Science (2010) 5.56
Lineage-specific biology revealed by a finished genome assembly of the mouse. PLoS Biol (2009) 5.45
ClinGen--the Clinical Genome Resource. N Engl J Med (2015) 4.45
Locus Reference Genomic sequences: an improved basis for describing human DNA variants. Genome Med (2010) 4.19
The carnegie protein trap library: a versatile tool for Drosophila developmental studies. Genetics (2006) 4.16
Public data archives for genomic structural variation. Nat Genet (2010) 3.92
Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation. PLoS Genet (2006) 3.54
Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation. Blood (2002) 3.54
Human immunodeficiency virus type 1, human protein interaction database at NCBI. Nucleic Acids Res (2008) 3.54
The cancer epigenome--components and functional correlates. Genes Dev (2006) 3.40
IgBLAST: an immunoglobulin variable domain sequence analysis tool. Nucleic Acids Res (2013) 3.33
A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus. Mol Cell Biol (2003) 3.09
Neuregulin-1 enhances depolarization-induced GABA release. Neuron (2007) 2.89
PcG proteins, DNA methylation, and gene repression by chromatin looping. PLoS Biol (2008) 2.85
Genome-wide prediction of conserved and nonconserved enhancers by histone acetylation patterns. Genome Res (2006) 2.67
Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study. Blood (2009) 2.57
Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol. Blood (2011) 2.35
The NIH genetic testing registry: a new, centralized database of genetic tests to enable access to comprehensive information and improve transparency. Nucleic Acids Res (2012) 2.35
De novo mutations in ATP1A3 cause alternating hemiplegia of childhood. Nat Genet (2012) 2.34
Glucose transporter-1 deficiency syndrome: the expanding clinical and genetic spectrum of a treatable disorder. Brain (2010) 2.21
The completion of the Mammalian Gene Collection (MGC). Genome Res (2009) 2.21
Current status and new features of the Consensus Coding Sequence database. Nucleic Acids Res (2013) 2.19
Locus Reference Genomic: reference sequences for the reporting of clinically relevant sequence variants. Nucleic Acids Res (2013) 2.18
A novel 6C assay uncovers Polycomb-mediated higher order chromatin conformations. Genome Res (2008) 2.10
The genome Assembly Archive: a new public resource. PLoS Biol (2004) 2.09
What everybody should know about the rat genome and its online resources. Nat Genet (2008) 1.94
The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation. Genes Dev (2002) 1.89
Tracking and coordinating an international curation effort for the CCDS Project. Database (Oxford) (2012) 1.78
The phenotypic spectrum of rapid-onset dystonia-parkinsonism (RDP) and mutations in the ATP1A3 gene. Brain (2007) 1.73
Adolescents with acute lymphoblastic leukaemia: outcome on UK national paediatric (ALL97) and adult (UKALLXII/E2993) trials. Pediatr Blood Cancer (2007) 1.68
The malaria secretome: from algorithms to essential function in blood stage infection. PLoS Pathog (2008) 1.67
The potential impact and optimal cut-points of using glycated haemoglobin, HbA1c, to detect people with impaired glucose regulation in a UK multi-ethnic cohort. Diabetes Res Clin Pract (2010) 1.65
Haematopoietic stem cell transplantation in haemophagocytic lymphohistiocytosis. Br J Haematol (2005) 1.64